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Clinical trials for Pain.

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    5,490 result(s) found for: Pain.. Displaying page 81 of 275.
    EudraCT Number: 2014-004857-15 Sponsor Protocol Number: SYL1001_III Start Date*: 2015-05-07
    Sponsor Name:Sylentis
    Full Title: DOSE-FINDING STUDY TO ASSESS THE SAFETY AND EFFECT OF SYL1001 IN PATIENTS WITH OCULAR PAIN
    Medical condition: Patients with eye pain associated to dry eye
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000408-16 Sponsor Protocol Number: HS-PM-013 Start Date*: 2005-04-05
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Caffeine-mediated modulation of human experimental pain models
    Medical condition: Healthy human volunteer subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001588-22 Sponsor Protocol Number: BUP-002/04 Start Date*: 2005-06-16
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: PHARMACOKINETIC/PHARMACODINAMIC STUDY OF TRANSDERMAL BUPRENORPHINE FOR TREATMENT OF CHRONIC, MEDIUM-SEVERE, NON-ONCOLOGIC PAIN.
    Medical condition: PATIENTS WITH CHRONIC, MEDIUM-SEVERE, VASCULOPATIC PAIN NON-RESPONDERS TO FANS.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006198-26 Sponsor Protocol Number: SAG-44/DIV Start Date*: 2007-07-23
    Sponsor Name:University of Nottingham
    Full Title: Mechanistic randomised contorlled trial of Mesalazine in symptomatic diverticular disease
    Medical condition: Symptomatic diverticular disease defines as patients with recurrent abdominal pain on more then 3 days per month with proven diverticula.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002638-19 Sponsor Protocol Number: 2012GR03 Start Date*: 2013-10-21
    Sponsor Name:University of Dundee & NHS Tayside
    Full Title: The Effect of Spironolactone on Pain in Older People with Osteoarthris
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005032-29 Sponsor Protocol Number: EPP Start Date*: 2013-09-10
    Sponsor Name:Association Bigorre Douleurs
    Full Title: Transmucosal Effentora® efficacy and safety for pre-emptive procedural pain treatment in opioid tolerant cancer patients.
    Medical condition: Painful procedures requiring analgesia in patients receiving already opioids for their background pain.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001721-13 Sponsor Protocol Number: TAK-013/EC-302 Start Date*: 2005-01-24
    Sponsor Name:Takeda Europe R&D Center Ltd
    Full Title: A Phase III, multi-center, randomized, double-blind study to evaluate the efficacy and safety of 50 mg and 100 mg of sufugolix (TAK-013) tablets administered twice daily versus placebo for 12 weeks...
    Medical condition: Endometriosis
    Disease: Version SOC Term Classification Code Term Level
    7 10014778 LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2005-000654-67 Sponsor Protocol Number: FM1 Start Date*: 2005-04-12
    Sponsor Name:Uppsala University/Uppsala County Council
    Full Title: Can patients with fibromyalgia be improved by subcutaneous injections of sterile water in tenderpoints? A randomised, controlled, tripple masked clinical trial
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001159-20 Sponsor Protocol Number: STH14404 Start Date*: 2008-09-25
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: A Prospective, Multi-centre, Single-Arm, Open Label Study of the Long term Use of a LHRH Agonist (Decapeptyl® SR, 11.25 mg) in Combination with Livial® Add-back Therapy in the Management of Chronic...
    Medical condition: Chronic cyclical pelvic pain
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038604 - Reproductive system and breast disorders 10064189 Chronic pelvic pain syndrome LLT
    13.1 10038604 - Reproductive system and breast disorders 10014778 Endometriosis PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005661-20 Sponsor Protocol Number: SKP-021-01-11 Start Date*: 2012-07-13
    Sponsor Name:PROMO INTERNATIONAL SRL
    Full Title: A double-blind, randomised, parallel group, active controlled, multicentre study to assess the therapeutic non-inferiority of SKP-021, a 0.3% ketoprofen patch, versus diclofenac sodium patch in pat...
    Medical condition: patients with painful and inflammatory conditions (e.g.: back pain, bruise, contusion, sprain, strains)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023754-37 Sponsor Protocol Number: 2010JTW01 Start Date*: 2011-01-28
    Sponsor Name:Ashford and St Peters Hospitals NHS Trust
    Full Title: Local Anaesthetic Infusion for Laparoscopic Hysterectomy: A Randomised controlled trial
    Medical condition: women having a total laparoscopic or vaginally assisted laparoscopic hysterectomy
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-003643-38 Sponsor Protocol Number: 17-HPNCL-01 Start Date*: Information not available in EudraCT
    Sponsor Name:Fondation Lenval - Hôpitaux Pédiatriques de Nice CHU-LENVAL
    Full Title: INTRANASAL KETAMINE IN THE REDUCTION OF THE ISOLATED FRACTURES OF THE HIGHER MEMBER OF THE CHILD TO PEDIATRIC EMERGENCIES
    Medical condition: a fracture isolated from the distal end of the closed upper limb, requiring a reduction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10016997 Forearm fracture PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000821-37 Sponsor Protocol Number: O3NPIQ Start Date*: 2019-12-10
    Sponsor Name:Bernardino Clavo - Hospital Universitario de G. C. Dr. Negrín
    Full Title: Effectiveness and cost-effectiveness of Ozone therapy in patients with pain secondary to chemotherapy-induced peripheral neuropathy. Randomized, triple-blind clinical trial.
    Medical condition: Pain secondary to chemotherapy-induced peripheral neuropathy.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10079545 Chemotherapy induced peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003602-26 Sponsor Protocol Number: CBA106191 Start Date*: 2007-05-04
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A double-blind, two-period, placebo controlled cross-over study of the effects of the CB2 agonist GW842166 on pain and sensitisation in patients with osteoarthritis.
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020475-23 Sponsor Protocol Number: B0041007 Start Date*: 2010-10-05
    Sponsor Name:Pfizer Inc.235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 2 RANDOMIZED, DOUBLE-BLINDED, DOUBLE-DUMMY, PLACEBO AND ACTIVE CONTROLLED TWO COHORT TWO-WAY CROSS-OVER, MULTI-CENTRE CLINICAL TRIAL TO EXAMINE THE PAIN RELIEF PRODUCED BY 2 WEEKS OF DAILY...
    Medical condition: Chronic pain in patients with Osteo-arthritis.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004856-41 Sponsor Protocol Number: CCTU0178 Start Date*: 2020-03-19
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: Regeneration in Cervical Degenerative Myelopathy - a multi-centre, double-blind, randomised, placebo controlled trial assessing the efficacy of Ibudilast as an adjuvant treatment to decompressive s...
    Medical condition: Degenerative Cervical Myelopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-003466-25 Sponsor Protocol Number: 13.024 Start Date*: 2014-12-18
    Sponsor Name:Anders Gadegaard Jensen,Anesthesia and Intensive Care Unit, Odense University Hospital
    Full Title: Randomized, double-blind, prospective, placebo-controlled trial of the effect of intravenous lidocaine infusion for postoperative pain management and bowel function in robot assisted laparoscopic c...
    Medical condition: Postoperative pain after colon rectal cancer surgery are mainly intended to relieve as well resting as activity-induced pain. Secondarily, the choice of pain management should take into considerati...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004864 10018017 Gastrointestinal tract cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-002607-18 Sponsor Protocol Number: 101.04 Start Date*: 2012-08-30
    Sponsor Name:Marius Henriksen
    Full Title: COMBINED INTRA ARTICULAR CORTICOSTEROID AND EXERCISE IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE: A RANDOMISED TRIAL
    Medical condition: Knee Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-005240-93 Sponsor Protocol Number: 1.3_amendment patientantal Start Date*: 2007-03-13
    Sponsor Name:Karolinska University Hospital
    Full Title: The effect of localanastetic when the drainage is removed, including women operated for breast cancer. [Svensk titel: effekt av lokalbedövning vid dränage borttagning].
    Medical condition: Patients undergoin surgery for breast cancer, according to DSMIV.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006264-27 Sponsor Protocol Number: Anapen 1 Start Date*: 2007-03-08
    Sponsor Name:Medeca Pharma AB
    Full Title: Smärtskattning av adrenalinpenna
    Medical condition: Patients with atopic allergy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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