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Clinical trials for Chronic Pain

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,162 result(s) found for: Chronic Pain. Displaying page 9 of 59.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next» Last»»
    EudraCT Number: 2010-021995-27 Sponsor Protocol Number: OXN3506 Start Date*: 2011-07-13
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomised, double-blind, double-dummy, parallel-group multicenter study to demonstrate improvement in symptoms of constipation and non-inferiority in analgesic efficacy in subjects with non-mali...
    Medical condition: The intended indication is: Severe pain, which can be adequately managed only with opioid analgesics. The opioid antagonist naloxone is added to counteract opioid-induced constipation by blocki...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    16.1 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) DE (Completed) FI (Completed) DK (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2006-006678-12 Sponsor Protocol Number: 05ct149fe Start Date*: 2007-06-29
    Sponsor Name:Haupt Pharma Wolfratshausen GmbH
    Full Title: Nasal Transmucosal Fentanyl Citrate (NTFC) versus Oral Morphine Sulphate (OMS): A double-blind, double dummy, randomised, multi-centre, comparative cross-over study for the treatment of breakthroug...
    Medical condition: Cancer-related breakthrough pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064556 Breakthrough pain LLT
    Population Age: Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019998-14 Sponsor Protocol Number: KF5503/58 Start Date*: 2011-02-15
    Sponsor Name:Grünenthal GmbH
    Full Title: Evaluation of the effectiveness, safety, and tolerability of tapentadol PR versus a combination of tapentadol PR and pregabalin in subjects with severe chronic low back pain with a neuropathic pain...
    Medical condition: severe chronic low back pain with a neuropathic pain component
    Disease: Version SOC Term Classification Code Term Level
    12.1 10024891 Low back pain LLT
    12.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) AT (Completed) BE (Completed) ES (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-002398-57 Sponsor Protocol Number: OXN3001 Start Date*: 2005-11-23
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomized, double-blind, parallel-group, multicenter study to demonstrate improvement in symptoms of constipation in subjects with non-malignant pain taking oxycodone equivalent of >= 20 mg/day ...
    Medical condition: Moderate to severe non-malignant pain that requires around the clock opioid therapy and also have constipation secondary to opioid treatment.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) DE (Completed) CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001261-16 Sponsor Protocol Number: Betapred_vid_tonsillektomi Start Date*: 2018-10-02
    Sponsor Name:ÖNH-kliniken Sunderby Sjukhus
    Full Title: Betamethasone (Betapred®) as premedication for reducing postoperative vomiting and pain after tonsillectomy – a randomized, double-blind, placebo-controlled trial
    Medical condition: Postoperative pain, nausea and vomiting following tonsillectomy in patients with chronic or recurrent tonsillitis.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004527-19 Sponsor Protocol Number: LAL1 Start Date*: 2006-01-30
    Sponsor Name:MRC Health Services Research Collaboration
    Full Title: Joint pain personalised treatment assessment to investigate the acceptability of modified release oxycontin for managing chronic pain in patients with osteoarthritis of the hip
    Medical condition: Hip Osteoarthritis
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005124-38 Sponsor Protocol Number: RADISAC Start Date*: 2021-11-18
    Sponsor Name:DARYD
    Full Title: Conditioned Autologous Serum Therapy (Orthokine) on the dorsal root ganglion in patients with chronic radiculalgia (RADISAC)
    Medical condition: lower extremity radicular pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2019-002858-23 Sponsor Protocol Number: PI2019_843_0051 Start Date*: 2019-11-20
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Serratus plain block versus paravertebral block versus serratus plain block and paravertebral block for postoperative pain following thoracoscopic surgery
    Medical condition: postoperative pain following thoracoscopic surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005079-40 Sponsor Protocol Number: IMP 11818 Start Date*: 2005-11-03
    Sponsor Name:Bayer Consumer Care, Research & Development
    Full Title: Placebo and active controlled, double dummy phase II study to prove efficacy of Aspirin (1000 mg solid dose) in treatment of acute low back pain.
    Medical condition: Acute body pain, specifically low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003230-18 Sponsor Protocol Number: Study No.: PRG-BUP-03/01 Start Date*: 2005-08-04
    Sponsor Name:Barts and The London NHS Trust
    Full Title: A prospective double-blind, randomised, cross-over trial to compare the effects of adding buprenorphine or morphine to Transtec for 'breakthrough' pain in patients with severe pain due to osteoarth...
    Medical condition: Patients with severe chronic pain (6 or more on a 11-point NRS) in the hips or knees due to osteoarthritis, failing on their current analgesic therapy. ICD 10: M16.50 & M17.30
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003365-34 Sponsor Protocol Number: Artralgia1 Start Date*: 2013-10-25
    Sponsor Name:Specialisttandvårdskliniken Västmanlands sjukhus Västerås
    Full Title: Pain relief following an intra-articular single dose metylprednisolon vs. placebo on temporomandibular joint artralgia patientens. A randomized controlled blinded multicenter study.
    Medical condition: Artralgia of the jaw joint
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005467-32 Sponsor Protocol Number: n.a. Start Date*: 2016-08-08
    Sponsor Name:Haga Teaching Hospital
    Full Title: A randomised controlled trial on the effect of laxative therapy in children with functional abdominal pain
    Medical condition: Functional abdominal pain
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016065-29 Sponsor Protocol Number: GWCA0962 Start Date*: 2010-03-10
    Sponsor Name:GW Pharma Ltd.
    Full Title: A double blind, randomized, placebo-controlled, parallel group study of Sativex oromucosal spray (Sativex®; Nabiximols) as adjunctive therapy in relieving uncontrolled persistent chronic pain in pa...
    Medical condition: Pain in patients with advanced cancer, who experience inadequate analgesia during optimized chronic opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) DE (Completed) PL (Completed) BG (Completed) HU (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2018-000269-36 Sponsor Protocol Number: HIPAIN Start Date*: 2018-05-23
    Sponsor Name:JORGE ORDUÑA VALLS
    Full Title: Randomized clinical trial to evaluate the efficacy of two techniques against chronic hip pain: cooled radiofrequency over sensitive nerves of the hip, compared to intraarticular injection of steroi...
    Medical condition: Chronic Hip Pain by Osteoarthrosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022905-17 Sponsor Protocol Number: GWCA1103 Start Date*: 2011-12-26
    Sponsor Name:GW Pharma Ltd.
    Full Title: A two-part, placebo-controlled, study of the safety and efficacy of Sativex oromucosal spray (Sativex®; Nabiximols) as adjunctive therapy in relieving uncontrolled persistent chronic pain in patien...
    Medical condition: Pain in patients with advanced cancer who have inadequate analgesia even with optimized chronic opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) GB (Completed) LT (Completed) PL (Completed) DE (Completed) HU (Completed) RO (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2009-018118-21 Sponsor Protocol Number: OXN2503 Start Date*: Information not available in EudraCT
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: An exploratory, randomised, double-blind, placebo-controlled, parallel group, pilot study to assess the analgesic efficacy of oxycodone/naloxone prolonged release tablets (OXN PR) compared to place...
    Medical condition: Bladder Pain Syndrome (BPS), formerly addressed as IC/PBS (interstitial cystitis /Painful Bladder Syndrome)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10008927 Chronic interstitial cystitis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) HU (Completed) CZ (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002655-24 Sponsor Protocol Number: SMR-1850/2PX-SP-02 Start Date*: 2008-09-30
    Sponsor Name:SantoSolve A/S
    Full Title: A randomised, double-blind, placebo (vehicle) controlled, parallel group study of the efficacy, safety and tolerability of topical 2PX (strontium chloride hexahydrate) in patients with chronic, mod...
    Medical condition: Post amputation patients (at least 6 months prior to visit 1) with chronic moderate-to-severe lower limb stump pain, defined as average stump pain on a daily basis (≥40 on a 100 mm pain VAS scale) ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023931 Late amputation stump complication LLT
    Population Age: Gender: Male, Female
    Trial protocol: DK (Completed) GB (Prematurely Ended) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004796-35 Sponsor Protocol Number: EPICLO2006 Start Date*: 2007-04-20
    Sponsor Name:R&D Department, Box 146, Addenbrooke's Hospital
    Full Title: A study of effect of epidural clonidine on postoperative pain relief, hyperalgesia and chronic pain in patients undergoing colorectal surgery
    Medical condition: 1. Postoperative pain and hyperalgesia following laparotomy for colorectal surgery 2. Chronic pain following laparotomy for colorectal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002273-12 Sponsor Protocol Number: Onco2008 Start Date*: 2008-06-23
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Long term opioid administration in oncologic chronic pain: open label, prospective study on efficacy, safety and pharmacogenetic factors.
    Medical condition: oncologic chronic pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058019 Cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003803-39 Sponsor Protocol Number: 11.0126 Start Date*: 2012-08-08
    Sponsor Name:St George's University of London
    Full Title: Pain management in osteoarthritis using the centrally acting analgesics duloxetine and pregabalin
    Medical condition: Hand osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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