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Clinical trials for Ear

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    371 result(s) found for: Ear. Displaying page 9 of 19.
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    EudraCT Number: 2017-003495-31 Sponsor Protocol Number: CCLL442X2201 Start Date*: 2017-12-14
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, Investigator-and patient-blind, placebo-controlled, parallel group first in human and proof of concept study to evaluate the safety, tolerability, and efficacy of CLL442 in patients w...
    Medical condition: Cutaneous Squamous Cell Carcinoma in situ (SCCis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041834 Squamous cell carcinoma of skin PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000166-21 Sponsor Protocol Number: 1 Start Date*: 2007-06-22
    Sponsor Name:Whipps Cross University Hospital
    Full Title: A comparison of the efficacy of 10% lidocaine solution and EMLA cream as local anaesthetic for the insertion of tympanic membrane ventilation tubes.
    Medical condition: Grommet/ventilation tube insertion in adults with otitis media with effusion (glue ear).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024759 Local anaesthetic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024283-18 Sponsor Protocol Number: AF219-006 Start Date*: 2011-05-20
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A Study to Assess the Efficacy of AF-219, a P2X3 Receptor Antagonist, in Subjects with Chronic Cough
    Medical condition: Subjects with Chronic Cough
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003896-37 Sponsor Protocol Number: BronSin2013 Start Date*: 2014-01-28
    Sponsor Name:URSAPHARM Arzneimittel GmbH
    Full Title: Efficacy and tolerability of Bromelain tablets hysan® in patients with chronic rhinosinusitis. A prospective, double-blind, randomized, placebo-controlled multi-centre trial. A proof of concept stu...
    Medical condition: Patients suffering from chronic rhinosinusitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-001081-80 Sponsor Protocol Number: NL22172 Start Date*: 2008-06-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort...
    Medical condition: To determine whether a 7-day duration of antibiotic treatment is non inferior to 14-day standard duration of treatment in adults presenting at primary care or emergency department with febrile uri...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002726-20 Sponsor Protocol Number: C-08-32 Start Date*: 2017-11-07
    Sponsor Name:Alcon Research Ltd
    Full Title: Safety of PATANASE® Nasal Spray in Patients With Perennial Allergic Rhinitis
    Medical condition: Perennial Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10034382 Perennial allergic rhinitis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-001720-36 Sponsor Protocol Number: BAY E 4465/11764 Start Date*: 2005-10-24
    Sponsor Name:BAYER
    Full Title: A pivotal, placebo controlled, phaseIII study to compare efficacy and tollerability of a fixed combination, containing 500 mg ASA and 30 mg Pseudoephedrine, in comparison to its single components i...
    Medical condition: Cold related pain/fever e.g. sore throat, headache, ear eache, sinus pressure and nasal congestion.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10028735 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000877-23 Sponsor Protocol Number: JM/JS/4551 Start Date*: 2005-04-11
    Sponsor Name:Oxford Radcliffe Hospitals NHS trust
    Full Title: Is Remifentanil better than Propofol in providing optimal conditions for an awake fibreoptic intubation?
    Medical condition: Awake fibre optic intubation is an anaesthetic technique used to intubate patients with a difficult to manage airway. It s a procedure by which a tracheal tube is inserted in a patients trachea wh...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005187-25 Sponsor Protocol Number: BUC-SI-11-001 Start Date*: 2012-05-31
    Sponsor Name:SOCIETA' LABORATORIO FARMACEUTICO S.I.T. SRL
    Full Title: Efficacy and tolerability clinical trial of an immunostimulant made from inactivated bacteria (BUCCALIN) in the prophylaxis of infection of the airways (rhinotracheobronchitis, colds). Double-blind...
    Medical condition: Episodes classified by upper respiratory infections (otitis, tonsillitis, sinusitis, pharyngotonsillitis, nasopharyngitis) and lower respiratory tract (bronchitis, pneumonia).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10060693 Respiratory tract infection bacterial PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001529-41 Sponsor Protocol Number: 0887X1-4596 Start Date*: 2017-06-02
    Sponsor Name:Pfizer Inc.
    Full Title: Prevenar Post-Licensure Safety Study in Russia: Frequency Of Fever Post Vaccination
    Medical condition: Infants from 3 months up to 23 months of age who may benefit from active immunization against disease caused by Streptococcus pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F and 23F (including sepsis...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-003970-16 Sponsor Protocol Number: C-07-02 Start Date*: 2017-11-22
    Sponsor Name:Alcon Research Ltd
    Full Title: Safety and Pharmacokinetics of PATANASE in Paediatric Patients 2 to < 6 Years of Age with a history of allergic rhinitis
    Medical condition: Allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10001723 Allergic rhinitis LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-001460-42 Sponsor Protocol Number: HMR 3647A/4023 Start Date*: 2004-11-16
    Sponsor Name:Aventis Intercontinental - Sanofi-aventis
    Full Title: A prospective, randomized, open-label, active-controlled study in adult subjects with acute bacterial sinusitis comparing the clinical efficacy of telithromycin (KETEK®) 800 mg once a day for 5 da...
    Medical condition: acute bacterial sinusitis (ABS)
    Disease: Version SOC Term Classification Code Term Level
    7.0 10000858 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003837-42 Sponsor Protocol Number: CF.CIP.1 Start Date*: 2005-09-26
    Sponsor Name:Belfast City Hospital Trust
    Full Title: CIPROFLOXACIN-INDUCED PHOTOTOXICITY IN PATIENTS WITH CYSTIC FIBROSIS
    Medical condition: infection - ciprofloxacin is used to treat various infections, for example respiratory tract infections, ear, nose and throat infections, eye infections, urinary tract infections. The main indicati...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002743-41 Sponsor Protocol Number: EA-15-01-996 Start Date*: 2016-11-22
    Sponsor Name:Engelhard Arzneimittel GmbH & Co. KG
    Full Title: Prospective, randomized, double-blind, placebo-controlled, parallel-group, multi-center trial to evaluate the efficacy and safety of cineole vs. placebo in the treatment of acute non-purulent rhino...
    Medical condition: Acute, non-purulent rhinosinusitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10052106 Rhinosinusitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005205-19 Sponsor Protocol Number: LPA112356 Start Date*: 2009-01-27
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A randomised, double-blind, placebo-controlled, 3-period cross-over study to evaluate the effect of two doses of GSK2190915 on the allergen-induced early asthmatic response in subjects with mild as...
    Medical condition: Mild asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001705 Allergic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-016581-80 Sponsor Protocol Number: HZA113090 Start Date*: 2010-01-22
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomised, double-blind, placebo-controlled, three-way crossover, repeat dose pilot study comparing the effect of inhaled fluticasone furoate/GW642444M combination and fluticasone furoate on the...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10001705 Allergic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-002414-12 Sponsor Protocol Number: 12082.101 Start Date*: Information not available in EudraCT
    Sponsor Name:PARI Pharma GmbH
    Full Title: A randomised, open, controlled pilot study to investigate the efficacy and safety of Buparid/PARI SINUS versus Budes® Nasal Spray in the therapy of Chronic Rhinosinusitis (CRS) with polyposis nasi ...
    Medical condition: Chronic Rhinosinusitis (CRS) with polyposis nasi
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000260-24 Sponsor Protocol Number: NAC600-ZI-L-01-06 Start Date*: 2007-05-21
    Sponsor Name:ZAMBON ITALIA
    Full Title: EVALUATION OF THE CLINICAL AND MICROBIOLOGICAL EFFICACY OF N-ACETILCISTEINA 600 MG, IN COMBINATION TO CEFPODOXIMA PROXETILE, IN THE THERAPY OF THE INFECTIONS OF THE HIGH RESPIRATORY WAYS IN ADULT P...
    Medical condition: Infection of the high respiratory ways in adult patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004054 Bacterial upper respiratory tract infections HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002421-30 Sponsor Protocol Number: 12082.102 Start Date*: 2014-06-06
    Sponsor Name:PARI Pharma GmbH
    Full Title: A randomised, open, controlled pilot study to investigate the potential of Buparid/PARI SINUS versus Budes® Nasal Spray to avoid or postpone sinus surgery in adult patients with Chronic Rhinosinu...
    Medical condition: Chronic Rhinosinusitis (CRS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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