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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 9 of 19.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next» Last»»
    EudraCT Number: 2004-001201-10 Sponsor Protocol Number: FEN-PPA-401 Start Date*: 2004-07-26
    Sponsor Name:JANSSEN-CILAG
    Full Title: Comparison of transdermal fentanyl PCA and IV morphine PCA in the management of post-operative pain control.
    Medical condition: Treatment of moderate to severe post-operative pain in subjects who have undergone an elective major abdominal or orthopaedic surgical procedure.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10056350 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-002936-34 Sponsor Protocol Number: iPROVE-O2-16 Start Date*: 2017-01-30
    Sponsor Name:Francisco Javier Belda Nacher
    Full Title: Effects on surgical site infection of an individualized perioperative openlung ventilatory strategy with high versus conventional inspiratory oxygen fraction (iPROVEO2). A comparative, prospective,...
    Medical condition: The study population will be patients who are scheduled for major abdominal (laparotomy and laparoscopic) surgery under general anaesthesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002051-15 Sponsor Protocol Number: KM-HYPO Start Date*: 2014-11-04
    Sponsor Name:Innsbruck Medical University, Department of Radiology, Section of Microinvasive Therapy
    Full Title: Systemic hypotension following intravenous administration of contrast medium during computed tomography.
    Medical condition: Primary goal of this study is to quantify changes in systolic and diastolic blood pressure, heart rate and pO2 before and after i.v. administration of either IOCM or LOCM. In particular the occurre...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-002555-34 Sponsor Protocol Number: ECSEVO-LT-011 Start Date*: 2011-11-25
    Sponsor Name:FRANCISCO JAVIER BELDA
    Full Title: Study on the safety of administration of sevoflurane for long-term sedation in critical patients on assisted ventilation. A multicentric, randomised, controlled, prospective clinical trial.
    Medical condition: The general objective of this study is to perform an assessment of the safety of administration of sevoflurane for prolonged sedation of patients admitted to the Critical Care Unit.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002911-18 Sponsor Protocol Number: 19.4.313 Start Date*: 2007-09-05
    Sponsor Name:NV Organon
    Full Title: Comparison of the T4/T1 ratio measured by means of the TOF-Watch® SX with the reappearance of T4 measured by means of a peripheral nerve stimulator in adult subjects receiving 4.0 mg.kg-1 sugammade...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005050-47 Sponsor Protocol Number: 19.4.304 Start Date*: 2006-01-24
    Sponsor Name:NV Organon
    Full Title: A multi-center, parallel-group, comparative trial evaluating the efficacy, pharmacokinetics and safety of Org 25969 in subjects with normal or impaired renal function.
    Medical condition: Not Applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005502-29 Sponsor Protocol Number: 2011-441 Start Date*: 2012-01-12
    Sponsor Name:Mona R Gätke
    Full Title: Optimization of surgical conditions during laparoscopic cholecystectomy with deep or moderate neuromuscular blockade
    Medical condition: Surgical conditions during laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10008611 Cholecystectomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000442-21 Sponsor Protocol Number: RC17_0029 Start Date*: 2017-09-12
    Sponsor Name:CHU de Nantes
    Full Title: Effects of perioperative administration of dexamethasone on postoperative complications and mortality after non-cardiac major surgery : a randomized, multicentre, double blind, study
    Medical condition: non-cardiac major surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2022-001023-32 Sponsor Protocol Number: RACE_01 Start Date*: 2022-09-14
    Sponsor Name:Medical University of Vienna
    Full Title: The effect of epinephrine, norepinephrine and phenylephrine on intraoperative hemodynamic performance - a prospective double-blinded, randomized clinical trial
    Medical condition: Patients > 45 years of age at-risk for cardiovascular complications undergoing moderate- to high-risk major open abdominal surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-003623-29 Sponsor Protocol Number: 63227.091.17 Start Date*: 2018-03-27
    Sponsor Name:Radboudumc
    Full Title: MRI measurement of the effects of moderate versus deep neuromuscular blockade on the abdominal working space during laparoscopic surgery in a prospective cohort study.
    Medical condition: We will investigate the effect of deep neuromuscular blockade on the abdominal working space. We will include patients undergoing laparoscopic surgery, including laparoscopic donor nephrectomy, lap...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004295-28 Sponsor Protocol Number: STER-AMVR-01 Start Date*: 2014-11-14
    Sponsor Name:Oulu University Hospital, Department of Anaesthesia
    Full Title: Postoperative pain management after heart valve surgery using parasternal block and PCA Oxycodone
    Medical condition: Mitral or aortic valve disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10049495 Heart valve operation NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022971-79 Sponsor Protocol Number: PALO-10-14 Start Date*: 2011-05-23
    Sponsor Name:Helsinn Healthcare SA
    Full Title: A Multicenter, Double-blind, Double-dummy, Randomized, Parallel Group, Stratified Study to Evaluate the Efficacy and Safety of a Single IV Dose of Palonosetron Compared to a Single IV Dose of Ondan...
    Medical condition: Postoperative nausea and vomiting (PONV)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10036238 Postoperative vomiting LLT
    14.0 10022117 - Injury, poisoning and procedural complications 10036285 Postoperative nausea LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2017-003638-10 Sponsor Protocol Number: 2016_37 Start Date*: Information not available in EudraCT
    Sponsor Name:CHRU LILLE
    Full Title: INTRANASAL CLONIDINE PREDICTION IN PEDIATRIC SURGERY: RANDOMIZED STUDY AGAINST PLACEBO
    Medical condition: intra-nasal premedication instead of oral, intravenous or no premedication.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005325-23 Sponsor Protocol Number: SGB_HF_MEN Start Date*: 2014-06-20
    Sponsor Name:Rijnstate Hospital
    Full Title: Short-term Efficacy of Stellate Ganglion Block in Men to reduce Hot Flushes related to Androgen Deprivation Therapy
    Medical condition: Hot flushes due to androgen deprivation therapy
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000517-31 Sponsor Protocol Number: ANST_2014_KET Start Date*: 2014-06-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of perioperative ketamine on postoperative outcome – a randomized placebo-controlled trial
    Medical condition: Postoperative cognitive state
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022117 - Injury, poisoning and procedural complications 10049987 Confusion postoperative PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004578-29 Sponsor Protocol Number: P.sitsen.01 Start Date*: 2007-06-15
    Sponsor Name:Leids Universitair Medisch Centrum
    Full Title: The efficacy of intravenous versus rectal paracetamol: A randomized, prospective, double-blind placebo-controlled study
    Medical condition: Aims of the study 1)to compare the analgesic efficacy of intravenous versus rectal paracetamol versus placebo as assessed by VAS scores and PCA morphine consumption. 2)To assess the pharmacokinet...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006935-29 Sponsor Protocol Number: 19.4.328 Start Date*: 2008-06-12
    Sponsor Name:NV Organon
    Full Title: A multi-center, parallel-group, comparative trial evaluating the efficacy, pharmacokinetics and safety of 4.0 mg.kg-1 sugammadex administered at 1-2 PTC in subjects with normal or severely impaired...
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) NL (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000460-90 Sponsor Protocol Number: AGO/2006/002 Start Date*: 2006-03-09
    Sponsor Name:University Hospital Ghent
    Full Title: Echocardiographic study of the haemodynamic effects of remifentanil with and without glycopyrrolate in healthy children
    Medical condition: ASA I and II children
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019712-20 Sponsor Protocol Number: DCSP1 Start Date*: Information not available in EudraCT
    Sponsor Name:University of Oslo, Institute of Clinical Dentistry
    Full Title: D-CYCLOSERINE ENHANCEMENT OF EXPOSURE TREATMENT OF DENTALLY FEARFUL AND AVOIDANT CHILDREN. A PILOT STUDY
    Medical condition: Avoidance of dental care because of dental anxiety often result in reduced dental health and need for sedation or treatment in general anesthesia. Treatment of dental anxiety is time consuming and ...
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006934-33 Sponsor Protocol Number: 19.4.333 Start Date*: 2008-04-02
    Sponsor Name:NV Organon
    Full Title: A single center, open-label trial in subjects with severe renal impairment evaluating the dialysability of the sugammadex-rocuronium complex
    Medical condition: Not applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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