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Clinical trials for Heart Failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    1,476 result(s) found for: Heart Failure. Displaying page 9 of 74.
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    EudraCT Number: 2020-003497-48 Sponsor Protocol Number: EMPATHY Start Date*: 2021-11-29
    Sponsor Name:Medical University of Warsaw
    Full Title: Empagliflozin and dapagliflozin in patients hospitalized for acute decompensated heart failure (EMPATHY) – a phase III trial
    Medical condition: acute decompensated heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003662-14 Sponsor Protocol Number: GN17CA082 Start Date*: 2019-05-13
    Sponsor Name:NHS Greater Glasgow and Clyde [...]
    1. NHS Greater Glasgow and Clyde
    2. University of Glasgow
    Full Title: Patiromer-facilitated, dose-escalation of mineralocorticoid antagonists for the management of worsening congestion in people with heart failure and hyperkalaemia. A Phase IV, registry-based, rand...
    Medical condition: People with heart failure, worsening symptoms and signs of congestion and serum potassium >5mmol/L
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2005-000778-31 Sponsor Protocol Number: n3-PUFA-HF/1 Start Date*: 2005-02-08
    Sponsor Name:Dept. of Cardiology, Medical University of Vienna
    Full Title: OMEGA-3-POLYUNSATURATED FATTY-ACIDS (n3-PUFA) IN PATIENTS WITH SEVERE CHRONIC HEART FAILURE: EFFECTS ON ENDOTHELIAL FUNCTION, LEFT VENTRICULAR REMODELLING, NATRIURETIC PEPTIDE LEVELS, AND EXERCISE ...
    Medical condition: chronic heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000588-26 Sponsor Protocol Number: ICCE12.001 Start Date*: 2012-10-16
    Sponsor Name:Leiden University Medical Center
    Full Title: Pharmacokinetics of Levosimendan in children with acute heart failure
    Medical condition: Acute heart failure in children
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing) FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-006666-28 Sponsor Protocol Number: MyDySyA Start Date*: 2009-04-24
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Myocardial Dyssynchrony and Sympathetic activity by cardiac gated-SPECT in patients with heart failure treated with cardiac resynchronyzation
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    9.1 10007635 HLT
    9.1 10007635 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001136-12 Sponsor Protocol Number: FARM6YHYW4 Start Date*: 2008-01-07
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: LONG-TERM OXYGEN THERAPY (LTOT) IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) PATIENTS WITH MODERATE CHRONIC HYPOXEMIA AND CHRONIC HEART FAILURE
    Medical condition: COPD patients with moderate chronic stable hypoxemia and chronic heart failure.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 Respiratory, thoracic and mediastinal disorders SOC
    9.1 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003611-37 Sponsor Protocol Number: PREVENT-CINHF Start Date*: 2011-10-28
    Sponsor Name:AZIENDA OSPEDALIERA MAGGIORE DELLA CARITA' DI NOVARA
    Full Title: PRevEntion of cardiac and Vascular pEriprocedural complications in patients undergoiNg coronary angiography or angioplasTy: hydratation vs carbonates to prevent Contrast-Induced Nephropathy in pati...
    Medical condition: Patients undergoing coronary angiography or angioplasty
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019464-37 Sponsor Protocol Number: 2010-019464-37 Start Date*: 2011-04-14
    Sponsor Name:FONDAZIONE TOSCANA GABRIELE MONASTERIO
    Full Title: effects of dynamic co2 therapy in periodic breathing in heart failure patients
    Medical condition: Patients hospitalized for heart failure and central sleep apnea syndrome in the Cardiovascular Medicine Department, Fondazione G. Monasterio, Pisa
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000269-27 Sponsor Protocol Number: DSCK101 Start Date*: 2014-11-06
    Sponsor Name:German Foundation for Chronically Ill
    Full Title: Efficacy and tolerance of Beta Blocker and Procoralan uptitration in chronic heart failure patients under telemedical control: „70 bpm on day 28“
    Medical condition: Patients with chronic heart failure and resting heart rate of ≥ 75 bmp
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001259-36 Sponsor Protocol Number: D2452L00010 Start Date*: 2006-06-16
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, parallel group, single blind, multicentre, 9-month, phase IV study in a primary care setting, comparing treatment guided by clinical symptoms and signs and NT-proBNP vs treatment guid...
    Medical condition: Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001871-39 Sponsor Protocol Number: CY 1121 Start Date*: 2007-01-02
    Sponsor Name:Cytokinetics, Inc
    Full Title: A PHASE II, MULTI CENTRE, DOUBLE-BLIND, RANDOMISED, PLACEBO CONTROLLED, DOSE-ESCALATION, PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF CK-1827452 IN PATIENTS WITH STABLE HEART FAILURE.
    Medical condition: The drug is being developed for heart failure. This is the first study in patients with stable heart failure .
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002516-33 Sponsor Protocol Number: NCT01420393 Start Date*: 2015-09-03
    Sponsor Name:University of Ottawa Heart Institute
    Full Title: A Randomized Ablation-based atrial Fibrillation rhythm control versus rate control Trial in patients with heart failure and high burden Atrial Fibrillation
    Medical condition: The study is comparing two accepted treatment methods (rhythm control-Catheter ablation with or without anti-arrhythmic drug control of maintaining sinus rhythm versus rate controls with medical th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003380-38 Sponsor Protocol Number: Oxyperform Start Date*: 2014-09-23
    Sponsor Name:R&D department, Hull and East Yorkshire Hospitals NHS Trust
    Full Title: The effect of oxygen on exercise performance in chronic heart failure
    Medical condition: Chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-001407-37 Sponsor Protocol Number: CKI- 301 Start Date*: 2007-06-20
    Sponsor Name:NovaCardia Inc (wholly owned subsidiary of Merck & Co. Inc)
    Full Title: A multicentre, randomised, double-blind, placebo-controlled study of the effects of KW-3902 Injectable Emulsion on heart failure signs and symptoms and renal function in subjects with acute heart f...
    Medical condition: Patients being admitted to hospital for acute heart failure (AHFS) with volume overload and renal impairment.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) CZ (Completed) HU (Completed) IT (Completed) NL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-003059-36 Sponsor Protocol Number: Bay 58-2667/12480 Start Date*: 2007-12-10
    Sponsor Name:Bayer Healthcare AG
    Full Title: Placebo controlled, randomized, double-blind, multi-center, multinational Phase IIb study to investigate the efficacy and tolerability of BAY 58-2667 given intravenously in patients with acute deco...
    Medical condition: Patients with acute decompensated chronic congested heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064653 Acute decompensated heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Prematurely Ended) IT (Prematurely Ended) SE (Prematurely Ended) EE (Prematurely Ended) CZ (Prematurely Ended) ES (Prematurely Ended) SI (Prematurely Ended) HU (Prematurely Ended) PL (Prematurely Ended) DE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-000413-48 Sponsor Protocol Number: 8.1(IRE),2017.03.24 Start Date*: 2015-07-01
    Sponsor Name:ACS Biomarker
    Full Title: Bioprofiling response to mineralocorticoid receptor antagonists for the prevention of heart failure. A proof of concept clinical trial within the EU FP 7 “HOMAGE” programme « Heart OMics in AGing
    Medical condition: Elderly patients with Clinical and Biological risk factors for developing heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) NL (Prematurely Ended) GB (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-002646-35 Sponsor Protocol Number: 8514077463 Start Date*: 2005-10-18
    Sponsor Name:Franz Volhard Clinic, Charite Campus Buch
    Full Title: Pilot study for evaluation of growth factor erythropoietin beta for improvement of left ventricular function after coronary interventions
    Medical condition: Ischemic heart failure is a major public health burden in western societies. Although technical advancements have improved recascularization of ischemic heart tissue in recent years, data on funct...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000708-18 Sponsor Protocol Number: CL3-16257-063 Start Date*: 2006-08-23
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Effects of ivabradine on cardiovascular events in patients with moderate to severe chronic heart failure and left ventricular systolic dysfunction. A three-year randomised double-blind placebo-cont...
    Medical condition: cardiac failure chronic
    Disease: Version SOC Term Classification Code Term Level
    9.0 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) BE (Completed) DE (Completed) NL (Completed) LT (Completed) DK (Completed) LV (Completed) FI (Completed) SI (Completed) CZ (Completed) EE (Completed) SK (Completed) IE (Completed) GB (Completed) BG (Completed) IT (Completed) PT (Completed) GR (Completed) AT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-003836-53 Sponsor Protocol Number: CCM S79/407 Start Date*: 2007-08-23
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: INFLUENCE OF ACETAZOLAMIDE AND CO2 INHALATION ON PERIODIC BREATHING DURING EXERCISE IN CHRONIC HEART FAILURE
    Medical condition: chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-002650-48 Sponsor Protocol Number: UCDCRC/22/02 Start Date*: 2023-05-05
    Sponsor Name:University College Dublin
    Full Title: The impact of Empagliflozin on Left atrIal Volume and the feasibility of using Fitbit and mHealth to prescribe Exercise in non-diabetic Pre- Heart Failure (ELIVE pre-HF Study)
    Medical condition: pre-heart failure with preserved ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004849 10076396 Heart failure with preserved ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Trial now transitioned)
    Trial results: (No results available)
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