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Clinical trials for Rheumatic Disease

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    564 result(s) found for: Rheumatic Disease. Displaying page 9 of 29.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next» Last»»
    EudraCT Number: 2012-003881-42 Sponsor Protocol Number: M13-692 Start Date*: 2013-01-24
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2b, Multicenter, Open-Label Study in Rheumatoid Arthritis Subjects who Completed Preceding Study M13-390 with Adalimumab
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) RO (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2010-019438-28 Sponsor Protocol Number: 2010-019438-28 Start Date*: 2010-05-17
    Sponsor Name:Mälarsjukhuset Eskilstuna
    Full Title: Vaccination against TBE in patients who use immunosuppressive drugs
    Medical condition: TBE vaccin in patients using immunosuppressive drugs
    Disease: Version SOC Term Classification Code Term Level
    12.1 10046859 Vaccination LLT
    12.1 10037153 Psoriasis LLT
    12.1 10039073 Rheumatoid arthritis LLT
    12.1 10054980 Immunosuppressant drug therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004894-16 Sponsor Protocol Number: H9B-MC-BCDH Start Date*: 2009-02-12
    Sponsor Name:Eli Lilly and Company limited
    Full Title: Phase 2, Dose-Ranging Study of Multiple Subcutaneous Doses of LY2127399, an Anti-BAFF Human Antibody, in Patients with Active Rheumatoid Arthritis Despite Ongoing Methotrexate Therapy
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) CZ (Prematurely Ended) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-004694-26 Sponsor Protocol Number: P1200/001 Start Date*: 2007-09-17
    Sponsor Name:Saint-Luc Universitary Hospital
    Full Title: A Comparative Study Of A 6-Month Infliximab (Remicade) Or Placebo Regimen In Undifferentiated Arthritis At High Risk For The Development Of Rheumatoid Arthritis : Clinical, Radiological (MRI) And S...
    Medical condition: Patient with undifferentiated arthritis and the presence of anti-CCP antibodies are at high risk to develop RA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003307-30 Sponsor Protocol Number: RA0123 Start Date*: 2015-04-16
    Sponsor Name:UCB Celltech, UK Registered Branch of UCB Pharma SA
    Full Title: A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Multiple Doses of UCB4940 Administered as Add-On to Certolizumab Pegol...
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed) CZ (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014394-41 Sponsor Protocol Number: WRAP Start Date*: 2009-10-12
    Sponsor Name:Hvidovre Hospital
    Full Title: Adalimumab in rheumatoid arthritis. An investigation of changes in disease activity and course of joint destruction by use of 3 Tesla Whole-Body MRI, dedicated 3 Tesla MRI and CT of the hand, and s...
    Medical condition: Reumatoid artritis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003268 Arthritis rheumatoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-003955-14 Sponsor Protocol Number: AMT-101-204 Start Date*: 2020-12-21
    Sponsor Name:Applied Molecular Transport Inc.
    Full Title: A Randomized, Double-blind, Placebo-controlled, Parallel Group, Exploratory Phase 2 Study of the Efficacy and Safety of Oral AMT-101 in Adults with Active Rheumatoid Arthritis who have demonstrated...
    Medical condition: Active Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-006669-40 Sponsor Protocol Number: CURACTA Start Date*: 2023-04-20
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Plasma cell depletion as an approach to reset autoimmunity in rheumatoid arthritis
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-003877-91 Sponsor Protocol Number: TOLERA Start Date*: 2019-06-13
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Sequential B cell/T cell therapy to re-induce humoral immune tolerance in ACPA-positive Rheumatoid Arthritis (TOLERA): a prospective randomized controlled open-label single-centre clinical trial in...
    Medical condition: Active rheumatoid arthritis with ACPA antibodies failing methotrexate
    Disease: Version SOC Term Classification Code Term Level
    23.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001999-38 Sponsor Protocol Number: TNF-K-006 Start Date*: 2013-10-07
    Sponsor Name:Neovacs SA
    Full Title: A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Clinical Efficacy of Neovacs’ TNF-Kinoid in Adult Subjects with Active Rheumatoid Arthritis despite Methotrexate Therapy
    Medical condition: Active Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) HU (Prematurely Ended) CZ (Prematurely Ended) PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-006001-10 Sponsor Protocol Number: RTX500/1000 Start Date*: 2012-03-19
    Sponsor Name:A.O. UNIVERSITARIA INTEGRATA DI VERONA
    Full Title: Efficacy of rituximab at the dose of 500 mg e.v., two infusions two weeks apart, versus rituximab at the usual dose of 1000 mg, two infusions two weeks apart, in patients affected by rheumatoid art...
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003268 Arthritis rheumatoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001847-20 Sponsor Protocol Number: MA21488 Start Date*: 2008-10-17
    Sponsor Name:F Hoffmann-La Roche Ltd
    Full Title: Estudio aleatorizado, controlado con placebo, para evaluar la seguridad y eficacia de añadir tocilizumab (TCZ) a metotrexato (MTX) frente al cambio a TCZ (controlado con placebo), con la posibilida...
    Medical condition: Artritis reumatoide
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) EE (Completed) DK (Completed) FR (Completed) NL (Completed) SE (Completed) IT (Completed) LV (Completed) GR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002951-18 Sponsor Protocol Number: GEN411/OFA110634 Start Date*: 2007-12-10
    Sponsor Name:Genmab A/S
    Full Title: A double-blind, randomized, placebo controlled, parallel group, multi-center, phase III trial of ofatumumab investigating clinical efficacy in adult patients with active rheumatoid arthritis who ha...
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) IT (Completed) ES (Completed) GB (Completed) FR (Completed) SE (Completed) DK (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003433-10 Sponsor Protocol Number: GP17-302 Start Date*: 2016-06-08
    Sponsor Name:Hexal, AG
    Full Title: GP17-302 A randomized, double-blind, parallel-group, multicenter study to demonstrate similar efficacy and to compare safety and immunogenicity of GP2017 and Humira® in patients with moderate t...
    Medical condition: rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    19.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) GB (Completed) DE (Completed) HU (Completed) RO (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-021449-28 Sponsor Protocol Number: PHRI10 – DM – AFORA Start Date*: 2010-10-04
    Sponsor Name:CHRU de TOURS
    Full Title: Valeur prédictive de la concentration sérique d’Adalimumab (Humira) sur la réponse clinique dans la polyarthrite rhumatoïde
    Medical condition: Polyarthrite rhumatoïde
    Disease: Version SOC Term Classification Code Term Level
    12.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011105-17 Sponsor Protocol Number: ML22462 Start Date*: 2009-05-17
    Sponsor Name:ROCHE
    Full Title: A single-arm, open-label study of early improvement of anemia and fatigue during treatment with tocilizumab (TCZ) in combination with non biologic DMARDs, in adult patients with moderate to severe ...
    Medical condition: Rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022049-88 Sponsor Protocol Number: ML22985 Start Date*: 2011-01-05
    Sponsor Name:Roche Pharma AG
    Full Title: "Efficacy and safety study of a sequential therapy of tocilizumab (TCZ) and, if initially inade-quately responded to tocilizumab (TCZ), followed by rituximab (RTX) in DMARD-IR patients with rheumat...
    Medical condition: Rheumatoid Arthritis (RA)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020499-50 Sponsor Protocol Number: N/A Start Date*: 2011-02-07
    Sponsor Name:South Tees Hospitals NHS Foundation Trust
    Full Title: Changes in bone density and bone turnover in patients with rheumatoid arthritis treated with rituximab, a B cell depleting monoclonal antibody. An investigator-led, industry supported, multicentre,...
    Medical condition: rheumatoid arthritis
    Disease: Version SOC Term Classification Code Term Level
    13 10039073 rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004062-13 Sponsor Protocol Number: NPDEP0206 Start Date*: 2006-07-18
    Sponsor Name:A.U.S.L. RIMINI
    Full Title: Randomised, open label, no profit, clinical, multicenter study of phase II and IIIB to assess efficacy and tolerability of oxycodone/paracetamol compared to anti-inflammatory non-steroidal drugs F...
    Medical condition: RHEUMATOID ARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    6.1 10039073 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012185-32 Sponsor Protocol Number: ML22413 Start Date*: 2009-11-23
    Sponsor Name:ROCHE
    Full Title: Open label, multicentric phase IIIb study to evaluate the effect of tocilizumab in combination with DMARDs in the inhibition of progression of synovitis, bone marrow edema, and erosions evaluated b...
    Medical condition: Moderate to severe active rheumatoid arthritis (RA), who are inadequate responders to DMARDs.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10039073 Rheumatoid arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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