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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 958 of 2,219.
    EudraCT Number: 2004-000953-46 Sponsor Protocol Number: SOV301 Start Date*: 2004-10-13
    Sponsor Name:Amersham plc
    Full Title: A Multicentre, Phase 3, Open-Label, Controlled Study Evaluating the Efficacy and Safety of 0.1 mmol/kg Omniscan (Gadodiamide Injection) in Magnetic Resonance Angiography (MRA) of the Renal Arteries
    Medical condition: Renal artery stenosis (RAS) is implicated as the underlying cause in 1% to 5% of patients with hypertension and 5% to 15% of patients with end-stage renal disease entering dialysis programs each ye...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005163-29 Sponsor Protocol Number: 05BFCH/Co04 Start Date*: 2006-03-09
    Sponsor Name:IBSA (Institut Biochimique SA)
    Full Title: “A multicentre, comparative, randomised, double-blind clinical trial on the equivalence of the efficacy and the safety of CHONDROSULF® 1200 mg, oral gel in sachet, once daily, versus CHONDROSULF® 4...
    Medical condition: Knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2005-000449-12 Sponsor Protocol Number: 104480 Start Date*: 2005-08-09
    Sponsor Name:GlaxoSmithKline
    Full Title: A phase II, double-blind, randomized, placebo controlled study to compare the immunogenicity, reactogenicity and safety of two different formulations of GlaxoSmithKline (GSK) Biologicals’ live atte...
    Medical condition: Immunization of healthy infants against HRV disease/illness.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-004955-36 Sponsor Protocol Number: CHR-2797-002 Start Date*: 2006-03-27
    Sponsor Name:Chroma Therapeutics Ltd.
    Full Title: A Phase I-II Study to Evaluate the Safety, Tolerability and Anti-Disease Activity of the Aminopeptidase Inhibitor, CHR-2797, in Elderly and/or Treatment Refractory Patients with Acute Myeloid Leuka...
    Medical condition: Treatment refractory Acute Myeloid Leukaemia (AML), Myelodysplastic Syndrome (MDS) or Multiple Myeloma (MM)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    9.1 10028535 Myelodysplastic syndrome unclassifiable LLT
    9.1 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003853-13 Sponsor Protocol Number: HPEPA-01 Start Date*: 2005-01-13
    Sponsor Name:Hela Pharma AB
    Full Title: Placebo controlled, randomised, double-blind, multicentre study of PlusEPA (a PUFA, Polyunsaturated Fatty Acids, supplement) as treatment for ADHD (combined type) with co-morbidity in Swedish child...
    Medical condition: ADHD (combined type) and co-morbidity in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006199-39 Sponsor Protocol Number: 310523 Start Date*: 2007-07-05
    Sponsor Name:Bayer AB, Bayer Schering Pharma
    Full Title: A double-blind, randomized, multi-center study to investigate the endometrial safety of a continuous, combined, oral estrogen/progestin preparation (0.5 mg 17b-estradiol [E2] / 0.25 mg drospirenone...
    Medical condition: Women suffering from postmenopausal symptoms
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050903 Postmenopausal symptoms LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002887-41 Sponsor Protocol Number: OV-W05 Start Date*: 2004-12-01
    Sponsor Name:OmniVision GmbH
    Full Title: Randomisierte, kontrollierte, für den Prüfer verblindete klinische Prüfung (Pilotstudie) zur Untersuchung der Wirksamkeit von Spersadex® Augentropfen im Vergleich zu Isopto®-Dex Augentropfen bei Pa...
    Medical condition: Nicht-infektiöse Conjunctivitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-005123-18 Sponsor Protocol Number: 104020 Start Date*: 2005-04-15
    Sponsor Name:GlaxoSmithKline
    Full Title: A phase III, partially blind, randomised, primary vaccination study to assess the immunogenicity and safety of three different lots of GlaxoSmithKline (GSK) Biologicals’ live attenuated measles-mum...
    Medical condition: Active immunization of healthy children during their second year of life against measles, mumps, rubella and varicella diseases.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004225-10 Sponsor Protocol Number: 3001081 Start Date*: 2005-03-07
    Sponsor Name:Orion Pharma
    Full Title: Effects of peroral levosimendan in the prevention of further hospitalisations in patients with chronic heart failure. A randomised, double-blind, placebo-controlled, multi-centre, parallel-group study
    Medical condition: Cardiac Failure
    Disease: Version SOC Term Classification Code Term Level
    7.1 10007554 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) LT (Completed) LV (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000408-41 Sponsor Protocol Number: RNA003142-302 Start Date*: 2004-10-07
    Sponsor Name:Ribapharm, Inc.
    Full Title: RANDOMIZED, DOUBLE–BLIND, MULTICENTER STUDY TO COMPARE THE SAFETY AND EFFICACY OF VIRAMIDINE TO RIBAVIRIN IN TREATMENT–NAïVE PATIENTS WITH CHRONIC HEPATITIS C
    Medical condition: Chronic Hepatitis C Viral Infection
    Disease: Version SOC Term Classification Code Term Level
    5.1 10008912 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003778-27 Sponsor Protocol Number: 0881A8-205 Start Date*: 2005-03-30
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc. Clinical resaearch and Development
    Full Title: A Randomized Double-Blind Placebo Controlled Trial Evaluating the Safety and Efficacy of Etanercept 25 mg Twice Weekly in Subjects with Moderate to Severe Persistent Asthma
    Medical condition: Moderate to severe asthmatics
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-004083-77 Sponsor Protocol Number: NO 002 CS 001 Start Date*: 2004-12-13
    Sponsor Name:Disphar International B.V.
    Full Title: A Randomised, International, Multicenter Study to assess the Efficacy and Safety of Mesalazine EC tablets 500 mg (4.5g/daily) and Salofalk® tablets 500 mg (4.5 g/daily) in the Treatment of Moderate...
    Medical condition: Moderate active Crohn disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000407-34 Sponsor Protocol Number: 0431-036 Start Date*: 2005-08-12
    Sponsor Name:MSD (Norge) AS
    Full Title: A Multicenter, Randomized, Double-Blind Factorial Study of the Co-Administration of MK-0431 and Metformin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    7.0 10045242 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) HU (Completed) GB (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005020-41 Sponsor Protocol Number: AMG 001 Start Date*: 2005-06-06
    Sponsor Name:Heinrich Heine Universität Düsseldorf
    Full Title: Topische Anwendung von Tacrolimus (Protopic) bei verschiedenen Formen des kutanen Lupus erythe-matodes im Rahmen einer klinischen Untersuchung an mehreren nationalen Zentren
    Medical condition: kutaner Lupus erythematodes Die Patienten zeigen meist an der Haut erythematöse Plaques im Rahmen dieser Erkrankung, welche häufig im Gesicht auftreten, schmerzempfindlich sind und zentral vernarb...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001540-71 Sponsor Protocol Number: JE049 #2102 Start Date*: 2005-07-23
    Sponsor Name:Jerini AG
    Full Title: Randomised, double blind, controlled, parallel group, multicentre study of a subcutaneous formulation of Icatibant vs. oral Tranexamic acid for the treatment of hereditary angioedema (HAE).
    Medical condition: Hereditary Angioedema (HAE)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed) AT (Completed) LT (Completed) IE (Completed) DE (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002769-18 Sponsor Protocol Number: MKC101614 Start Date*: 2005-05-03
    Sponsor Name:GlaxoSmithKline R&D
    Full Title: A 28-day, randomised, double-blind, placebo-controlled study to assess the safety, tolerability, anti-inflammatory effect and steadystate pharmacokinetics of SB-681323 7.5 mg per day in patients wi...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004415-29 Sponsor Protocol Number: DU176b-PRT007 Start Date*: 2005-04-18
    Sponsor Name:Daiichi Medical Research Inc
    Full Title: A Phase IIa, multi-center, multi-national, open-label, dose ranging study of the efficacy, safety, and tolerability of oral DU-176b administered once or twice daily in the treatment of adult patien...
    Medical condition: Prophylaxis of venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    7.1 10049909 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2005-000832-26 Sponsor Protocol Number: 2005 02 03 Start Date*: 2006-01-25
    Sponsor Name:Department of Endocrinology
    Full Title: Adjuvant treatment of Graves´ ophthalmopathy with NSAID (aGO study)
    Medical condition: Graves´ophthalmopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001150-88 Sponsor Protocol Number: MEN/03/ZOF-CHF/001 Start Date*: 2005-05-06
    Sponsor Name:Menarini International Operation Luxembourg -SA
    Full Title: Comparison between zofenopril and ramipril in combination with ASA on the extent of cardiovascular risk in patients with systolic left ventricular dysfunction after acute myocardial infarction (SMI...
    Medical condition: Systolic left ventricular dysfunction after AMI
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049694 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-000025-35 Sponsor Protocol Number: Al0204AV Start Date*: 2005-04-05
    Sponsor Name:Allergopharma Joachim Ganzer KG
    Full Title: A multicentre randomised placebo-controlled double-blind clinical trial for evaluation of safety and efficacy of specific immunotherapy with an aluminium hydroxide-adsorbed allergoid preparation of...
    Medical condition: IgE-mediated allergic diseases including allergic rhinitis/rhinoconjunctivitis, allergic bronchial asthma (GINA I and II) triggered by birch pollen allergens
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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