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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,344 result(s) found. Displaying page 958 of 2,218.
    «« First « Previous 954  955  956  957  958  959  960  961  962  Next» Last»»
    EudraCT Number: 2017-004929-33 Sponsor Protocol Number: SiccaIkervis Start Date*: 2018-12-05
    Sponsor Name:KH Hietzing, Department of Ophthalmology
    Full Title: Effect of Ciclosporin eyedrops on ocular symptoms and optical image quality in patients with primary or secondary Sjögren syndrome
    Medical condition: primary or secondary Sjögren Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003785-77 Sponsor Protocol Number: 59244 Start Date*: 2017-03-16
    Sponsor Name:
    Full Title: Microdosing as a tool to individualize docetaxel dosing: development of a limited sampling model
    Medical condition: Patients with breast-, prostate or non-small cell lung cancer (NSCLC), who are eligible for treatment with docetaxel.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001934-16 Sponsor Protocol Number: AMZ001-006 Start Date*: 2018-10-19
    Sponsor Name:Amzell BV
    Full Title: A placebo-controlled, double-blind, randomized, trial of Diclofenac Gel AMZ001 3.06 % for the treatment of knee osteoarthritis symptoms
    Medical condition: Knee Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-002889-11 Sponsor Protocol Number: D3560C00071 Start Date*: 2005-11-04
    Sponsor Name:AstraZeneca AB
    Full Title: An 18-Week, Randomized, Multicenter, Phase IIIb, Double-Blind, Crossover Study, Followed by an 18-Week Open-Label Period to Evaluate the Efficacy and Safety of the Lipid-Regulating Agents, Rosuvast...
    Medical condition: Dysbetalipoproteinemia (Fredrickson Type III Hyperlipoproteinemia)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2017-005010-59 Sponsor Protocol Number: THERAG0001 Start Date*: 2018-05-17
    Sponsor Name:Theragnostics Ltd
    Full Title: A Phase II, Open-label Study to Assess Safety and Clinical Utility of 68Ga-THP-PSMA PET/CT in Patients with High Risk Primary Prostate Cancer or Biochemical Recurrence after Radical treatment
    Medical condition: High Risk Primary Prostate Cancer or Biochemical Recurrence after Radical treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004401-40 Sponsor Protocol Number: RG_17-194 Start Date*: 2019-01-31
    Sponsor Name:University of Birmingham
    Full Title: STELLAR: A phase II, randomiSed study of CHOP-R in combination with acalabruTinib comparEd to CHOP-R in patients with newLy diagnosed Richter’s Syndrome (RS) and a pLAtfoRm for initial investigatio...
    Medical condition: Richter's Syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058728 Richter's syndrome PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058728 Richter's syndrome PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-002637-37 Sponsor Protocol Number: NL66693.058.18 Start Date*: 2020-06-29
    Sponsor Name:Leiden University
    Full Title: Manipulating NMDA-dependent learning to alter nocebo effects: A pharmacological fMRI study on pain and itch.
    Medical condition: Nocebo effects on pain and itch
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002820-20 Sponsor Protocol Number: OZBS62.14078 Start Date*: 2016-02-03
    Sponsor Name:Erasmus MC Dept. Urology
    Full Title: Are alpha blockers effective in the treatment of bladder elimination problems in female patients with Multiple Sclerosis?
    Medical condition: Bladder dysfunction in Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038359 - Renal and urinary disorders 10069632 Bladder dysfunction PT
    20.1 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-003867-21 Sponsor Protocol Number: LP0160-1327 Start Date*: 2017-10-30
    Sponsor Name:LEO Pharma A/S
    Full Title: A phase 4 trial comparing the efficacy of subcutaneous injections of brodalumab to oral administrations of fumaric acid esters in adults with moderate to severe plaque psoriasis
    Medical condition: moderate to severe plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-002195-14 Sponsor Protocol Number: KPPM-Hx Start Date*: 2019-11-12
    Sponsor Name:University Hospital "Príncipe de Asturias"
    Full Title: Randomized clinical trial to assess the monocitary functionality and their relationship with the administration of intravenous iron in patient in hemodialysis according to practice guidelines or ac...
    Medical condition: Monocyte function in patients with anemia in hemodialysis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10002272 Anemia LLT
    20.0 100000004848 10027884 Monocytes LLT
    20.1 100000004848 10005671 Blood monocytes normal LLT
    20.1 100000004848 10005669 Blood monocytes decreased LLT
    20.1 100000004848 10027881 Monocyte count low LLT
    20.1 100000004848 10027879 Monocyte count high LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001044-35 Sponsor Protocol Number: GQM00016 Start Date*: 2019-02-08
    Sponsor Name:Sanofi Pasteur SA
    Full Title: Immunogenicity and Safety of a Multi-Dose Quadrivalent Influenza Vaccine in Children Aged 6 months to 17 Years
    Medical condition: Prophylaxis of influenza (Northern Hemisphere 2017-2018 season) in children aged 6 months to 17 years
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-003690-10 Sponsor Protocol Number: 2125-MST-206 Start Date*: 2019-06-21
    Sponsor Name:Idera Pharmaceuticals, Inc.
    Full Title: Study of Tilsotolimod in Combination with Nivolumab and Ipilimumab for the Treatment of Solid Tumors
    Medical condition: Cohort 1: IO Naive Relapsed/Metastatic Squamous Cell Carcinoma of the Head and Neck
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060121 Squamous cell carcinoma of head and neck PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002443-42 Sponsor Protocol Number: GS-US-427-4024 Start Date*: 2017-01-09
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: A Phase 2, Randomized, Double-Blind, Placebo Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Subjects with Primary Biliary Cholangitis Without Cirrhosis
    Medical condition: Primary Biliary Cholangitis
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004871 10036680 Primary biliary cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003298-32 Sponsor Protocol Number: I6T-MC-AMAK Start Date*: 2018-07-10
    Sponsor Name:Eli Lilly and Company
    Full Title: A Multicenter Study with a Randomized, Double-Blind, Placebo-Controlled Induction Dosing Period Followed by a Randomized Withdrawal Maintenance Dosing Period to Evaluate the Efficacy and Safety of ...
    Medical condition: Moderate to Severe Plaque Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10071117 Plaque psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004685-33 Sponsor Protocol Number: NL67545 Start Date*: 2019-05-01
    Sponsor Name:azM
    Full Title: Surgical excision versus photodynamic therapy and topical 5-fluorouracil in treatment of Bowen’s disease: a multicenter randomized controlled trial
    Medical condition: Bowens's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001380-23 Sponsor Protocol Number: TASTE-001 Start Date*: 2020-02-21
    Sponsor Name:Franciscus Gasthuis en Vlietland
    Full Title: The effect of tamsulosin on the spontaneous passage of bile stones
    Medical condition: Choledocholithiasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000668-27 Sponsor Protocol Number: MBW-2017-01 Start Date*: 2019-09-19
    Sponsor Name:Marta Maia Boscá Watts
    Full Title: Pilot Project for the Treatment of Perianal Disease through the Local Injection of Remsima Guided by Ultrasound. Number of cases.
    Medical condition: Perianal disease (PD): alteration associated with inflammatory bowel disease (IBD) that includes fissures, ulcers, fistulas or abscesses, and is one of the most difficult aspects of treating IBD. B...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003367-35 Sponsor Protocol Number: AVT02-GL-301 Start Date*: 2019-02-03
    Sponsor Name:Alvotech Swiss AG
    Full Title: A Multicenter, Double-blind, Randomized, Parallel-group, Active Control Study to Compare the Efficacy, Safety, and Immunogenicity of AVT02 Versus Humira® in Patients with Moderate-to-Severe Chronic...
    Medical condition: Chronic Plaque Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10037153 Psoriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002926-19 Sponsor Protocol Number: CCSJ137X2201 Start Date*: 2017-11-30
    Sponsor Name:Novartis Pharma AG
    Full Title: A first-in-human, two-part (open label, and randomized/double blind/placebo controlled), single- and repeat-dose study of CSJ137 in erythropoietin-treated chronic hemodialysis patients with functio...
    Medical condition: Functional iron deficiency anemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10002272 Anemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-005026-39 Sponsor Protocol Number: QHD04 Start Date*: 2019-02-01
    Sponsor Name:Sanofi Pasteur Inc
    Full Title: Safety and Immunogenicity of Different Dosages of High-Dose Quadrivalent Influenza Vaccine in Children 6 months to 17 Years of Age
    Medical condition: Prevention of influenza infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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