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Clinical trials for Pain.

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    5,490 result(s) found for: Pain.. Displaying page 99 of 275.
    EudraCT Number: 2005-003514-15 Sponsor Protocol Number: ANTRO01-05 Start Date*: 2005-11-03
    Sponsor Name:BRACCO
    Full Title: CLINICAL EVALUATION OF EFFICACY AND TOLERABILITY OF ANTROLIN RETTAL CREME IN THE TREATMENT OF POSTHEMORROIDECTOMY PAIN. DUOBLE BLIND STUDY
    Medical condition: pOST-HEMORROIDECTOMY PAIN
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019022 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004042-14 Sponsor Protocol Number: 16-OBE2109-015 Start Date*: 2018-04-23
    Sponsor Name:ObsEva SA
    Full Title: An exploratory single centre, open label, pilot study investigating the efficacy and safety of OBE2109 200 mg daily for 12 weeks followed by 100 mg daily for 12 weeks in uterine adenomyosis.
    Medical condition: Uterine adenomyosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10058953 Adenomyosis uteri LLT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-001267-24 Sponsor Protocol Number: UCA-12-EC/21/ALO Start Date*: 2022-06-24
    Sponsor Name:Arthroscopic Surgery Unit
    Full Title: Pilot study to evaluate intra-articular infiltrations of allogeneic Platelet Rich Plasma (PRP) for the treatment of knee osteoarthritis.
    Medical condition: Knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002157-38 Sponsor Protocol Number: 57911 Start Date*: 2017-09-14
    Sponsor Name:Radboud University Medical Center
    Full Title: Treatment of congenital vascular malformations using Sirolimus: improving quality of Life
    Medical condition: congenital vascular malformation : Vascular malformations can involve lymphatic vessels, capillaries, veins and arteries or even combinations. These vascular malformations are present at birth an...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000005125 10047091 Vascular malformations and acquired anomalies HLT
    20.0 100000158692 10047090 Vascular malformation peripheral LLT
    20.0 10017947 - Gastrointestinal disorders 10070181 Gastrointestinal vascular malformation PT
    20.0 10010331 - Congenital, familial and genetic disorders 10074979 Vascular malformation PT
    Population Age: Infants and toddlers, Children, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-004875-11 Sponsor Protocol Number: CAMG334AIT03 Start Date*: 2019-05-29
    Sponsor Name:NOVARTIS FARMA S.P.A.
    Full Title: A RandomizEd, double-blind, cross-over Study to assess Erenumab effecT on BRAIN networks function and structure in comparison to placebo in episodic migraine patients (RESET BRAIN)
    Medical condition: Episodic migraine
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027599 Migraine PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-007069-35 Sponsor Protocol Number: 301106 Start Date*: 2007-01-22
    Sponsor Name:University Medical Centre St Radboud, Department of Dermatology
    Full Title: Evaluation of Neodymium YAG laser-treatment compared to topical treatment with betamethasondipropionaat/calcipotriol ointment (Dovobet) for patients with chronic plaque type psoriasis
    Medical condition: Chronic localized Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2022-004127-40 Sponsor Protocol Number: ESPSEVMOLIN2022 Start Date*: 2023-05-03
    Sponsor Name:Dra. Nuria Gutierrez Dubón
    Full Title: Clinical trial on the effectiveness and safety of botulinum toxin type A (incobotulinumtoxin) in doses adapted to the individual needs of patients with severe spasticity
    Medical condition: brain damage oriented spasticity
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005452-11 Sponsor Protocol Number: - Start Date*: 2022-01-21
    Sponsor Name:Medizinische Universität Innsbruck
    Full Title: Influence of the PECS II block on postoperative pain and opioid demand in patients undergoing minimal invasive cardiac surgery
    Medical condition: Patients scheduled for minimal invasive cardia surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001209-26 Sponsor Protocol Number: ICO-N-2018-14 Start Date*: 2019-06-11
    Sponsor Name:INSTITUT DE CANCEROLOGIE DE L'OUEST
    Full Title: Multicentre, randomized, controlled, open-label, multi-centre medico-economic study evaluating the efficacy of adding zoledronic acid to Stereotaxic radiotherapy in the treatment of vertebral metas...
    Medical condition: Patients, men or women over 18 old, with inoperable vertebral bone metastases who must beneficit treatment with stereotactic radiotherapy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10027484 Metastatic pain LLT
    20.0 100000004864 10027474 Metastatic LLT
    20.0 100000004864 10049038 Metastatic bone pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004986-28 Sponsor Protocol Number: AMOXI Start Date*: 2019-03-25
    Sponsor Name:Medizinische Universität Graz, Klin. Abteilung für Orale Chirurgie und Kieferorthopädie
    Full Title: Effect of systemic antibiotic therapy on postoperative complications in patients undergoing wisdom teeth removal surgery. A double-blind, randomised, placebo-controlled Trial
    Medical condition: Surgical extraction of third molars
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10047991 Wisdom teeth removal PT
    20.0 10042613 - Surgical and medical procedures 10038349 Removal of wisdom teeth LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2021-006621-22 Sponsor Protocol Number: COVIC-19-G Start Date*: 2022-02-14
    Sponsor Name:DRK-Blutspendedienst Baden-Württemberg - Hessen gGmbH
    Full Title: A Randomised Open-Label Trial of Early, Very High-Titre Convalescent Plasma Therapy in Clinically Vulnerable Individuals with Mild COVID-19 as model of early treatment in a pandemia with a new path...
    Medical condition: Clinically Vulnerable Individuals with Mild COVID-19
    Disease: Version SOC Term Classification Code Term Level
    23.1 10022891 - Investigations 10084355 COVID-19 virus test positive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000431-32 Sponsor Protocol Number: ORTHOUNION Start Date*: 2017-05-25
    Sponsor Name:Universidad Autónoma de Madrid (U.A.M.)
    Full Title: A MULTI-CENTRE, OPEN-LABEL, RANDOMIZED, COMPARATIVE CLINICAL TRIAL OF TWO DIFFERENT DOSES OF BONE MARROW AUTOLOGOUS HUMAN MESENCHYMAL STEM CELLS PLUS BIOMATERIAL VERSUS ILIAC CREST AUTOLOGOUS GRAFT...
    Medical condition: Diaphyseal and/or metaphysodiaphyseal fractures (femur, tibia, humerus) with status of non-union
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10017085 Fracture malunion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing) DE (Completed) FR (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006503-15 Sponsor Protocol Number: STA-LDH01 Start Date*: 2023-02-23
    Sponsor Name:Stayble Therapeutics
    Full Title: A prospective, randomised, double-blinded, placebo-controlled study investigating the safety and tolerability of STA363 in patients with radiculopathy caused by lumbar disc herniation
    Medical condition: Radiculopathy due to lumbar intervertebral disc herniation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    20.0 10029205 - Nervous system disorders 10050219 Lumbar radiculopathy PT
    20.0 10029205 - Nervous system disorders 10052772 Lumbar spinal cord and nerve root disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-003052-70 Sponsor Protocol Number: APAC2016 Start Date*: 2016-11-10
    Sponsor Name:Academic Medical Center of Amsterdam
    Full Title: Initial non-operative treatment strategy versus appendectomy treatment strategy for simple appendicitis in children aged 7-17 years old. APAC study
    Medical condition: Acute uncomplicated (simple) appendicitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10003011 Appendicitis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005565-12 Sponsor Protocol Number: MD01 Start Date*: 2013-02-18
    Sponsor Name:AZ Groeninge
    Full Title: The effect of low dose intravenous dexamethasone on the analgesic duration of single shot interscalene block with ropivacaine for shoulder surgery. A prospective, double blind, randomized, placebo ...
    Medical condition: Postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000239-29 Sponsor Protocol Number: PEC19156 Start Date*: 2021-07-09
    Sponsor Name:BIOGAIA PHARMA
    Full Title: A randomized placebo-controlled study to assess safety and preliminary efficacy of BGP345A in patients with constipation due to the use of opioid-based medications for the management of chronic non...
    Medical condition: Opioid induced constipation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-000520-35 Sponsor Protocol Number: ASSTBS-FARM-ONC-MERIDIAN-2020 Start Date*: 2021-05-27
    Sponsor Name:AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA
    Full Title: Multiparametric assessment of bone response in mCRPC patients treated with Cabozantinib upon progression to chemotherapy and next generation hormonal agents: a phase II study
    Medical condition: PATIENTS WITH BONE METASTASIS FROM PROSTATIC CARCINOMA
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000098-65 Sponsor Protocol Number: 09012313 Start Date*: 2013-09-13
    Sponsor Name:University of Tromsø
    Full Title: Treatment of Axial Spondyloarthritis with reduced doses of NSAIDs: Application of pharmacotherapeutic conditioning in clinical practice.
    Medical condition: Axial Spondyloarthritis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000585-21 Sponsor Protocol Number: prot RG 1 Start Date*: Information not available in EudraCT
    Sponsor Name:Royal Victoria Eye and Ear hospital
    Full Title: Randomised controlled trial of intravitreal Bevacizumab vs. conventional treatment for rubeotic glaucoma.
    Medical condition: Rubeotic glaucoma secondary to ischaemic proliferative retinopathies
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005442-39 Sponsor Protocol Number: Better Life in Osteoarthritis Start Date*: 2006-10-24
    Sponsor Name:Division of Rheumatology
    Full Title: Randomized controlled trial of prednisolone in the treatment of osteaoarthritis of the hand
    Medical condition: Osteoarthritis of the hands
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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