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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 998 of 2,219.
    EudraCT Number: 2008-004677-18 Sponsor Protocol Number: BRD07/11-U Start Date*: 2008-10-03
    Sponsor Name:CHU de Nantes
    Full Title: Etude prospective monocentrique: Analyse et corrélation de la réaction immunologique locale et systémique induite par des instillations endovésicales de BCG (Bacille de Calmette et Guérin) dans le ...
    Medical condition: Patients présentant un cancer superficiel de la vessie.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003694-41 Sponsor Protocol Number: D1443C00024 Start Date*: 2008-10-06
    Sponsor Name:Universidad de Granada
    Full Title: Ensayo clínico piloto aleatorizado, para evaluar la eficacia y tolerabilidad de quetiapina de liberación prolongada en comparación con la de amitriptilina en el tratamiento de pacientes con fibrom...
    Medical condition: Fibromialgia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003762-18 Sponsor Protocol Number: 2007.468/11 Start Date*: 2008-10-23
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Prospective monocenter accuracy study of Vasovist contrast enhanced magnetic resonance venography (CE-MRV) to detect venous thrombi in patients with Ultrasonography detected peripheral acute deep ...
    Medical condition: Acute deep vein thrombosis (DVT)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051055 Deep vein thrombosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007725-46 Sponsor Protocol Number: ASBI 307 Start Date*: 2009-02-06
    Sponsor Name:Asubio Pharmaceuticals, Inc.
    Full Title: A Phase 2b, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SUN11031 for Injection Administered Subcutaneously Twice Daily for 12 We...
    Medical condition: Cachexia associated with chronic obstructive pulmonary disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2006-003180-31 Sponsor Protocol Number: MC-ASP.5/ALL Start Date*: 2008-07-29
    Sponsor Name:medac GmbH
    Full Title: Comparative efficacy and safety of two asparaginase preparations in children with previously untreated acute lymphoblastic leukaemia
    Medical condition: Acute lymphoblastic leukaemia (ALL) is a clonal disease resulting from genetic mutations and transformation of a single early progenitor lymphoid cell. Uncontrolled expansion of leukaemic blasts in...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000844 Acute lymphoblastic leukaemia LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-005324-93 Sponsor Protocol Number: CSLCT-NHF-08-55 Start Date*: 2008-09-23
    Sponsor Name:CSL Limited
    Full Title: A Single Centre, Open-Label Study to Evaluate the Immunogenicity and Safety of Enzira® vaccine in Healthy ‘Adults’ aged ≥ 18 to < 60 years and in Healthy ‘Older Adults’ aged ≥ 60 years for the 2008...
    Medical condition: Prophylaxis of influenza
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022000 Influenza LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-003833-25 Sponsor Protocol Number: EFACLE2008 Start Date*: 2009-02-05
    Sponsor Name:Universitätskrankenhaus Schleswig-Holstein
    Full Title: Efficacy ans safety of subcutaneous Efalizumab in the treatment of patients with cutaneous lupus erythematosus: A mono-centre, open-label, prospective pilot study
    Medical condition: Cutaneous lupus erythematosus (discoid LE or subacute cutaneous LE) or systemic lupus erythematosus with cutaneous DLE or SCLE lesions without major organ involvment.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013071 Discoid lupus erythematosis LLT
    9.1 10057903 Subacute cutaneous lupus erythematosus LLT
    9.1 10056509 Cutaneous lupus erythematosus LLT
    Population Age: Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-006778-26 Sponsor Protocol Number: 07ct/am04perm Start Date*: 2008-07-17
    Sponsor Name:gepepharm GmbH
    Full Title: Investigation of the local tolerability of pedimitex creme 5% - a permethrine containing creme - in 100 patients with scabies infection of both gender
    Medical condition: The product is intended to be used by patients suffering from scabies infestation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039512 Scabies infestation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002288-14 Sponsor Protocol Number: HM1006 Start Date*: 2009-02-10
    Sponsor Name:University of Birmingham
    Full Title: Phase I Dose Escalation Study of Clofarabine and Liposomal Daunorubicin in Childhood and Adolescent AML
    Medical condition: Paediatric patients (6 months to 18 years) diagnosed with AML who are refractory to front line therapy, early first relapse (less than 1 year from diagnosis) and second and subsequent relapse patie...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000880 Acute myeloid leukaemia LLT
    9.1 10066764 Acute myeloid leukaemia progression LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004673-17 Sponsor Protocol Number: PHRC IR08 - Pr. FOURNIER Start Date*: 2009-03-23
    Sponsor Name:CHU d'Amiens
    Full Title: Comparaison du nicotinamide et du sevelamer hydrochloride sur le contrôle de la phosphatémie des hémodialysés chroniques
    Medical condition: Ostéodystrophie rénale
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002035-33 Sponsor Protocol Number: 65 plus Start Date*: 2009-04-20
    Sponsor Name:Martha-Maria Krankenhaus Halle-Dölau gGmbH
    Full Title: Open-label study of Bevacizumab (AVASTIN®) in combination with Pemetrexed or Pemetrexed and Carboplatin as first-line treatment of patients with advanced or recurrent non-squamous non-small cell lu...
    Medical condition: Patients with advanced metastatic or recurrent non- small cell lung cancer (NSCLC).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002390-13 Sponsor Protocol Number: notapplicable Start Date*: 2009-04-08
    Sponsor Name:University Hospital
    Full Title: Are cranberry capsules useful in preventing urinary tract infection in hip fracture patients with urinary tract catheter
    Medical condition: Urinary tract infections in patients with hip fractures.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046571 Urinary tract infection LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-006545-41 Sponsor Protocol Number: PPD/2007/AER 001 DPI/2b Start Date*: 2009-03-20
    Sponsor Name:Aerovance, Inc
    Full Title: A PHASE IIB STUDY TO INVESTIGATE THE TREATMENT-SPARING EFFECTS OF AEROVANT™ (AER 001 INHALATION POWDER) IN ASTHMA PATIENTS NOT FULLY CONTROLLED ON CURRENT THERAPY
    Medical condition: moderate persistent to severe persistent asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-003539-19 Sponsor Protocol Number: BAY63-2521/11349 Start Date*: 2008-11-26
    Sponsor Name:Bayer HealthCare AG,
    Full Title: Long-term extension, multi-centre, multi-national study to evaluate the safety and tolerability of oral BAY 63-2521 (1 mg, 1.5 mg, 2 mg, or 2.5 mg tid) in patients with Chronic Thromboembolic Pulmo...
    Medical condition: Chronic Thromboembolic Pulmonary Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10037406 Pulmonary hypertension secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) FR (Completed) AT (Completed) IT (Completed) IE (Prematurely Ended) ES (Completed) BE (Completed) CZ (Completed) PT (Completed) DK (Completed) SK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004543-11 Sponsor Protocol Number: 2008-517 Start Date*: 2008-10-03
    Sponsor Name:HOSPICES CIVILS DE LYON
    Full Title: COMBINA. Efficacité et tolérance des bithérapies oseltamivir + zanamivir ou oseltamivir + amantadine en comparaison avec la monothérapie oseltamivir dans le traitement de la grippe saisonnière A
    Medical condition: Grippe de type A confirmée
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000657-35 Sponsor Protocol Number: CUP ONE Start Date*: 2008-10-08
    Sponsor Name:Greater Glasgow and Clyde Health Board (GGCHB)/University of Glasgow
    Full Title: A multi-centre phase II trial to assess the efficacy of epirubicin, cisplatin and capecitabine incorporating the prospective validation of molecular classifiers and exploratory metabonomics.
    Medical condition: Metastatic Carcinomas of Unknown Primary origin (CUP)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007174-35 Sponsor Protocol Number: AM-KS-IV/5/07 Start Date*: Information not available in EudraCT
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: Randomized, placebo-controlled phase-IV clinical trial for the application of physostigmine salicylate for an early post-operative restoration of vigilance and cognition after cardiopulmonary bypas...
    Medical condition: post-operative restoration of vigilance and cognition after cardiopulmonary bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066123 Cardiopulmonary bypass LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004598-83 Sponsor Protocol Number: 54371254 Start Date*: 2008-10-22
    Sponsor Name:EBMT (European group for Blood and Marrow Transplantation)
    Full Title: High dose immunoablation and autologous hematopoietic stem cell transplantation versus monthly intravenous pulse therapy cyclophosphamide in severe systemic sclerosis ( ‘ASTIS’-TRIAL: Autologous S...
    Medical condition: Severe systemic sclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042953 Systemic sclerosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-002828-15 Sponsor Protocol Number: S 379 Start Date*: 2009-03-13
    Sponsor Name:Krankenhaus Nordwest GmbH
    Full Title: An open-label, uncontrolled phase II trial of single agent sunitinib (SU 11248) for patients with chemo-refractory metastatic melanoma
    Medical condition: chemo-refractory metastatic melanoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006829-13 Sponsor Protocol Number: 2005B118 Start Date*: 2008-02-19
    Sponsor Name:Netherlands Heart Foundation
    Full Title: Antiplatelet therapy in combination with Recombinant t-PA Thrombolysis in Ischemic Stroke
    Medical condition: Patients with ischemic stroke More specific patients with ischemic stroke treated with rt-PA thrombolysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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