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Clinical trials

The European Union Clinical Trials Register allows you to search for protocol and results information on:
  • interventional clinical trials that are conducted in the European Union (EU) and the European Economic Area (EEA);
  • clinical trials conducted outside the EU / EEA that are linked to European paediatric-medicine development.
  • Learn   more about the EU Clinical Trials Register   including the source of the information and the legal basis.


    The EU Clinical Trials Register currently displays   37219   clinical trials with a EudraCT protocol, of which   6124   are clinical trials conducted with subjects less than 18 years old.
    The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    6,124 result(s) found. Displaying page 1 of 307.
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    EudraCT Number: 2007-004507-36 Sponsor Protocol Number: CTBM100DDE01 Start Date*: 2008-08-19
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A multicenter, open label, 2 period cross-over study to evaluate the Pharmacokinetics of an 8 week continuous treatment with 1x300mg/d and 2x300mg/d TOBI® inhaled with the PARI eFlow® rapid in Cyst...
    Medical condition: patients with cystic fibrosis and chronical infection with Pseudomonas aeruginosa
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011763 Cystic fibrosis lung LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006696-36 Sponsor Protocol Number: E2090-E044-318 Start Date*: 2008-09-05
    Sponsor Name:Eisai Limited
    Full Title: Open label Extension Study Following Double-blind, Randomized, Placebo-controlled, Multicentre Study to Assess Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures associated with Idi...
    Medical condition: myoclonic seizures in idiopathic generalised epilepsy (IGE).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054859 Myoclonic epilepsy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-003484-45 Sponsor Protocol Number: 2007/3 Start Date*: 2007-05-25
    Sponsor Name:ISTITUTO ONCOLOGICO VENETO
    Full Title: PHASE II TRIAL OF FOLFIRI REGIMEN PLUS BEVACIZUMAB ALTERNATED WITH OXALIPLATIN-BASED HEPATIC ARTERIAL INFUSION PLUS DE GRAMONT REGIMEN AND BEVACIZUMAB IN THE TREATMENT OF UNRESECTABLE LIVER METASTA...
    Medical condition: UNRESECTABLE LIVER METASTASES FROM COLORECTAL CANCER
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029104 SOC
    Population Age: Children, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004396-19 Sponsor Protocol Number: HGosteo-BAY Start Date*: 2007-12-24
    Sponsor Name:ITALIAN SARCOMA GROUP
    Full Title: Phase II, open label, non-randomized study of second or third line treatment with sorafenib (BAY 43-9006) in patients affected by relapsed high-grade osteosarcoma.
    Medical condition: patients affected by relapsed high-grade osteosarcoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031296 Osteosarcoma recurrent LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004397-62 Sponsor Protocol Number: PI070274 Start Date*: 2008-11-28
    Sponsor Name:Servicio Andaluz de Salud
    Full Title: Análisis aleatorizado y doble ciego sobre la utilidad del extracto de arándano rojo vs profilaxis antibiótica con Trimetoprima en la infección urinaria recurrente infantil
    Medical condition: First clinical assay so far where the convenience is evaluated of carrying out prophylaxis of the pediatric urinary recurrent infection in the childhood with extract of cranberries (with a fixed co...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021872 Infection urinary tract LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006209-16 Sponsor Protocol Number: 152/2005/U/Sper Start Date*: 2006-03-06
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Evaluation of the role of 18F-di-idrossi-fenil-alanina 18F-DOPA in images diagnostic by Positron Emission Tomography PET in study of human neuroendocrin neoplasia.
    Medical condition: Neuroendocrin neoplasie carcinoid, thyroid medullary carcinoma, neuroendocrin neoplasie, feocromocitoma, melanoma and neuroblastoma .
    Disease: Version SOC Term Classification Code Term Level
    6.1 10014714 HLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003943-30 Sponsor Protocol Number: VomED Start Date*: 2005-11-22
    Sponsor Name:University of Leipzig
    Full Title: Doubleblind randomized multicenter trial to investigate the influence of dimenhydrinate suppositories vs. placebo on oral rehydration in infants and children with infectious enteritis and vomiting
    Medical condition: Infectious enteritis with vomiting
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058839 Enteritis infectious PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: View results
    EudraCT Number: 2007-007535-23 Sponsor Protocol Number: PUNS Start Date*: 2008-10-01
    Sponsor Name:St George's University of London
    Full Title: A phase IV study to evaluate the primary and booster immune responses of UK preterm infants receiving licensed DTaP/Hib/IPV and meningococcal C conjugate vaccine and incorporating a randomisation s...
    Medical condition: These are vaccines routinely given to infants in the UK and are not administered with respect to existing medical condition(s), rather in the prevention of diseases.
    Disease: Version SOC Term Classification Code Term Level
    15.0 10021881 - Infections and infestations 10027276 Meningococcal meningitis LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004153-22 Sponsor Protocol Number: 310788 Start Date*: 2007-04-18
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: Open-label multi-center study of magnetic resonance imaging (MRI) with 0.1 mmol/kg BW Gadovist (1.0 M) to assess pharmacokinetics, safety and tolerability in children
    Medical condition: Gadovist as diagnostic imaging agent is approved only for adult patients. Diseases usually representing indications for contrast-enhanced Magnetic Resonance Imaging (CE-MRI) are common also in a pe...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029815 Nuclear magnetic resonance imaging PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) DK (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005701-32 Sponsor Protocol Number: B4Z-IT-LYDS Start Date*: 2006-03-07
    Sponsor Name:ELI LILLY
    Full Title: An Open-Label Study of the Efficacy of Atomoxetine Hydrochloride on Quality of Life of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder with or without comorbid conditions
    Medical condition: Child or adolescent patients with Attention-Deficit/ Hyperactivity Disorder ADHD
    Disease: Version SOC Term Classification Code Term Level
    6.1 10003736 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003525-82 Sponsor Protocol Number: CSISP-VAC-MENC1 Start Date*: 2006-10-25
    Sponsor Name:Dirección General de Salud Pública; Conselleria de Sanidad de la Comunidad Valenciana
    Full Title: “Estudio clínico multicéntrico, abierto, aleatorizado, fase IV, para evaluar la inmunogenicidad de las vacunas de polisacáridos de meningococo C conjugados con toxoide tetánico o con CRM197, admini...
    Medical condition: Enfermedad meningocócica por serogrupo C
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004496-38 Sponsor Protocol Number: CPH-DDAVPISTH-1 Start Date*: 2006-06-22
    Sponsor Name:Rigshospitalet, Copenhagen
    Full Title: Desmopressin in the management of von Willebrand disease; Biological versus clinical efficacy.
    Medical condition: von Willebrand disease (VWD) is an inherited bleeding disorder, characterised mainly by mucosal bleedings, which may be life-threatening, and joint bleeds in severe VWD cases. VWD is caused by a la...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000602-23 Sponsor Protocol Number: 101-PG-COM-144 Start Date*: 2007-09-17
    Sponsor Name:Laboratorios LETI S.L.
    Full Title: A randomized double blind, placebo controlled study to evaluate the efficacy and security of immunotherapy with a depigmented and polymerized allergen extract of Dermatophagoides pteronyssinus in p...
    Medical condition: Mild to moderate asthma caused by sensitization againts dust mite Dermatophagoides Pteronyssinus.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001705 Allergic asthma LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: PT (Not Authorised)
    Trial results: (No results available)
    EudraCT Number: 2007-002788-28 Sponsor Protocol Number: RHM CHI434 Start Date*: 2008-01-15
    Sponsor Name:Southampton University Hospital NHS Trust
    Full Title: Evaluation of Corticosteroid therapy in Childhood Severe Sepsis (Steroids in Paediatric Sepsis, StePS) - a randomised pilot study
    Medical condition: Children with severe sepsis requiring mechanical ventilation presenting within 12 hours of onset. The majority of children will either have community acquired sepsis (most commonly meningococcal or...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10040047 Sepsis LLT
    9.1 10053840 Bacterial sepsis LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003254-10 Sponsor Protocol Number: UCL 08/0230 Start Date*: 2009-08-07
    Sponsor Name:University College London
    Full Title: A Phase II Study to determine the efficacy and safety of conventional dose oral Treosulfan in patients with advanced pre-treated Ewing’s Sarcoma
    Medical condition: Advanced and pre-treated Ewing’s Sarcoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015562 Ewing's sarcoma metastatic LLT
    9.1 10015564 Ewing's sarcoma recurrent LLT
    9.1 10015562 Ewing's sarcoma metastatic PT
    9.1 10015564 Ewing's sarcoma recurrent PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005897-54 Sponsor Protocol Number: S241-GB-08 Start Date*: 2006-02-01
    Sponsor Name:Stiefel Laboratories Maidenhead Ltd
    Full Title: A Phase 1, Single-Centre, Single-blind, CPO Solution Human Patch Test in Healthy Subjects
    Medical condition: Not Applicable (Healthy Volunteer Study)
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001886-40 Sponsor Protocol Number: G2M-777 SYS 01/2004 Start Date*: 2006-06-06
    Sponsor Name:TopoTarget Germany AG
    Full Title: A randomized, double-blind, placebo-controlled parallel group study to assess the safety and efficacy of a new oral formulation of 2-propyl pentanoic acid (2-PPA, PEAC minitablets) for the treatmen...
    Medical condition: Familial adenomatous polyposis
    Disease: Version SOC Term Classification Code Term Level
    7.1 10059327 LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-004829-97 Sponsor Protocol Number: S241-GB-01 Start Date*: 2005-01-05
    Sponsor Name:Stiefel Laboratories Maidenhead Ltd (commonly known as Stiefel International R&D)
    Full Title: 96 HOUR HUMAN PATCH TEST FOR ASSESSMENT OF PRIMARY SKIN IRRITATION
    Medical condition: Not Applicable (Healthy Volunteer Study)
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000130-39 Sponsor Protocol Number: NEO014/FP/pMDI/paed Start Date*: 2007-02-08
    Sponsor Name:Neolab Ltd
    Full Title: A PHASE III, RANDOMISED, DOUBLE-BLIND, DOUBLE-DUMMY, PLACEBO CONTROLLED CROSSOVER STUDY TO COMPARE THE SYSTEMIC EFFECTS OF INHALED FLUTICASONE PROPIONATE HFA MDI 200g PER DAY VERSUS THE REFERENCE ...
    Medical condition: Mild asthma in pre-pubertal children.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002365-21 Sponsor Protocol Number: BH4-1 Start Date*: 2004-11-03
    Sponsor Name:John F. Kennedy Institute
    Full Title: Trial with BH4, a new and simple treatment of phenylketonuria, PKU
    Medical condition: PKU, phenylketonuria, is a rare, inherited metabolic disease that results in mental retardation if not a very strict low-protein diet is started within the first weeks of life. The conversion of p...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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