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Clinical trials for Amiloride

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    26 result(s) found for: Amiloride. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-005655-42 Sponsor Protocol Number: AmilorideOGTT1 Start Date*: 2008-01-17
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital
    Full Title: STUDY TITLE: - Early Metabolic Changes with Thiazide or Beta blocker Therapy for Essential Hypertension – open label extension phase with the potassium sparing diuretic- Amiloride.
    Medical condition: Essential hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005113-39 Sponsor Protocol Number: SSP-2 Start Date*: 2013-04-08
    Sponsor Name:Universitätsklinik für Neurologie, Medizinische Universität Wien
    Full Title: A Randomized, Placebo-Controlled, Double-Blind, Phase IIa Study of Amiloride in the Treatment of Acute Autoimmune Optic Neuritis
    Medical condition: Optic neuritis is among the most common first symptoms of multiple sclerosis leading to significant atrophy of the optic nerve within a short period of time, thus reflecting neurodegneration.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004051-11 Sponsor Protocol Number: 1 Start Date*: 2008-12-18
    Sponsor Name:Oxford Racliffe NHS Trust
    Full Title: Amiloride Treatment in Multiple Sclerosis
    Medical condition: Multiple Sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004980-39 Sponsor Protocol Number: Amiloride02 Start Date*: 2013-01-21
    Sponsor Name:University of Oxford
    Full Title: A double blind randomised controlled trial on neuroprotection of amiloride in optic neuritis
    Medical condition: Optic Neuritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10030942 Optic neuritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-001288-18 Sponsor Protocol Number: 16-API-01 Start Date*: 2019-01-08
    Sponsor Name:CHU de Nice
    Full Title: ASIC channels and migraine disorders - Proof of concept study on the efficacy of Amiloride in prophylaxis of Migraine with Aura - APAM study
    Medical condition: Migraine with aura
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10027607 Migraine with aura PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003336-38 Sponsor Protocol Number: MED.RES.HOS.2008.01.SM. Start Date*: 2009-02-06
    Sponsor Name:Department of Medical Research
    Full Title: The effect of Amiloride and Spironolacton on renophysiological and cardiovascular parametres in healthy patients
    Medical condition: Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003637-96 Sponsor Protocol Number: NL54748.078.15 Start Date*: 2016-03-31
    Sponsor Name:
    Full Title: DD-study: diet or diuretics for salt-sensitivity in chronic kidney disease
    Medical condition: Hypertension in chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000433-40 Sponsor Protocol Number: NL72836.340.10 Start Date*: 2021-12-30
    Sponsor Name:Erasmus University Medical Centre Rotterdam
    Full Title: Treatment of vascular stiffness in patients with autosomal dominant polycystic kidney disease
    Medical condition: Autosomal dominant polycystic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020599-47 Sponsor Protocol Number: MED.RES.HOS.2010.02.SM Start Date*: 2010-06-29
    Sponsor Name:Departments of Medical Research and Medicine
    Full Title: The effect of Amiloride and Spironolacton on renophysiological and cardiovascular parametres in patients with hypertension
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.1 10004254 Benign essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004746-81 Sponsor Protocol Number: Start Date*: 2009-07-20
    Sponsor Name:Parnassia-BAVO groep [...]
    1. Parnassia-BAVO groep
    2. St. Elisabeth Ziekenhuis
    3. University Medical Center Utrecht
    Full Title: Effect of amiloride on lithium-induced chronic nephropathy. Comparing discontinuation of lithium treatment to adding amiloride while continuing lithium treatment.
    Medical condition: Renal failure due to long-term use of lithium salts in patients with bipolar disorders.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004938 Bipolar disorders HLT
    9.1 10009121 Chronic renal failure worsened LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002607-18 Sponsor Protocol Number: AmiloridNS-01 Start Date*: 2020-02-11
    Sponsor Name:University Hospital Tuebingen
    Full Title: Randomized, controlled interventional trial to investigate the efficacy of amiloride for the treatment of edema in human nephrotic syndrome
    Medical condition: Nephrotic syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001202-84 Sponsor Protocol Number: lithium-15-12-06 Start Date*: 2007-02-01
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Comparison of the action of amiloride and thiazide in the reduction of lithium-NDI in patients with affective disorders
    Medical condition: Lithium-induced Nephrogenic Diabetes Insipidus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012600 Diabetes insipidus nephrogenic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-004329-90 Sponsor Protocol Number: OGTT Version 3. 18.05.07 Start Date*: 2005-02-08
    Sponsor Name:CAMBRIDGE UNIVERSITY HOSPITALS FOUNDATION NHS TRUST
    Full Title: EARLY METABOLIC CHANGES WITH THIAZIDE OR BETA BLOCKER THERAPY FOR ESSENTIAL HYPERTENSION (MAIN STUDY).
    Medical condition: ESSENTIAL HYPERTENSION
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001929-24 Sponsor Protocol Number: 1392-H-199 Start Date*: 2011-09-19
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital 12 de Octubre
    Full Title: Randomised, open-label, crossover clinical trial to evaluate the antiproteinuric effect of three different types of diuretics (hydrochlorothiazide, amiloride and spironolactone) in patients with ch...
    Medical condition: Chronic proteinuric nephropathies
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005394-31 Sponsor Protocol Number: 12/0219 Start Date*: 2014-04-01
    Sponsor Name:UCL
    Full Title: MS-SMART: A Multi-Arm Phase IIb Randomised, Double Blind Placebo-Controlled Clinical Trial Comparing The Efficacy of Three Neuroprotective Drugs in Secondary Progressive Multiple Sclerosis
    Medical condition: Mutliple Sclerosis (Secondary Progressive)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000637-35 Sponsor Protocol Number: Glory 2 Start Date*: 2006-07-07
    Sponsor Name:Addenbrookes Hospital Cambridge University Hospitals NHS Foundation Trust
    Full Title: double blind crossover compariosn of diuretics in young patients with low-renin hypertension
    Medical condition: Low-renin hypertension
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002049-35 Sponsor Protocol Number: AC-056-201 Start Date*: 2007-07-22
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: "Estudio unicéntrico, a doble ciego, aleatorizado y controlado con placebo, cruzado de 2 brazos, para investigar el efecto de miglustat sobre la diferencia de potencial nasal en pacientes con fibr...
    Medical condition: fibrosis quística
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011762 Cystic fibrosis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-017033-22 Sponsor Protocol Number: 24052 Start Date*: 2010-02-12
    Sponsor Name:Odense University Hospital
    Full Title: Syd Dansk Hypertensions- og Diabetes Studie Et prospektivt, dobbeltblindet, randomiseret multicenterstudie af effekten af spironolakton på blodtrykket hos type 2 diabetikere med behandlingsresiste...
    Medical condition: At undersøge i et randomiseret, placebokontrolleret, dobbeltblindet interventionsforsøg, om tillæg af spironolakton til anden antihypertensiv behandling af behandlingsresistente hypertonikere med t...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10005727 Blood pressure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-001946-26 Sponsor Protocol Number: AMITNED Start Date*: 2016-01-19
    Sponsor Name:Aarhus University Hospital
    Full Title: Amilorid treatment of nephrotic edema
    Medical condition: Childhood idiopathic nephrotic syndrome (NS)
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005056-32 Sponsor Protocol Number: P060215 Start Date*: 2007-03-01
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Exploration clinique, biologique et pharmacologique d'un polymorphisme de NEDD 4-2, protéine régulatrice du canal sodium épithélial
    Medical condition: Etude chez des sujets normovolontaires dont le but est de détecter d'éventuelles anomalies de réabsorption sodée qui soient la conséquence du polymorphisme de la protéine Nedd4-2.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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