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Clinical trials for Antihypertensive

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    463 result(s) found for: Antihypertensive. Displaying page 1 of 24.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2004-004933-32 Sponsor Protocol Number: km 55/2004 – LORISTAH/CZ Start Date*: 2005-03-04
    Sponsor Name:KRKA, d. d., Novo mesto
    Full Title: Efficacy and safety of Lorista and Lorista H in the treatment of mild to moderate arterial hypertension
    Medical condition: mild to moderate hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2018-004809-58 Sponsor Protocol Number: HEBRO-001 Start Date*: 2019-04-04
    Sponsor Name:Institute for study, research, education and therapy of vascular, heart, brain and kidney nosologies (I.N.A.K.E.N)
    Full Title: Comparative study of eplerenone-based treatment strategy versus irbesartan-based blood pressure lowering in obese hypertensive patients (HEBRO Study)
    Medical condition: Primary Hypertension and Obesity
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10020775 Hypertension arterial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-006981-40 Sponsor Protocol Number: hypertension2006-006981-40 Start Date*: 2007-05-03
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust jointly with University of Cambridge
    Full Title: Does the underlying haemodynamic abnormality determine response to antihypertensive therapy in patients with hypertension?
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004254 Benign essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003410-12 Sponsor Protocol Number: RG_19-169 Start Date*: 2020-12-16
    Sponsor Name:University of Birmingham
    Full Title: Pregnancy ANtihypertensive Drugs: which Agent is best?
    Medical condition: Hypertension in pregnancy (chronic hypertension, gestational hypertension or pre-eclampsia)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2004-004231-53 Sponsor Protocol Number: 506067 Start Date*: 2004-12-22
    Sponsor Name:Royal Devon and Exeter NHS Foundation Trust
    Full Title: The Effect Of Antihypertensive Treatment With Lisinopril and Labetalol on Baroreflex Sensitivity in Stroke
    Medical condition: Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000538-12 Sponsor Protocol Number: HLK-VASC-11/01 Start Date*: 2011-06-14
    Sponsor Name:VU University Medical Center
    Full Title: An exploratory open-label PET-observer-blinded pilot study to evaluate the effect of 3 and 12 months treatment with Aliskeren-based versus amlodipin-based antihypertensive treatment in patients wit...
    Medical condition: Abdominal Aortic Aneurysm Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002545-32 Sponsor Protocol Number: CR0002 Start Date*: 2019-11-06
    Sponsor Name:Ablative Solutions, Inc
    Full Title: A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System™ Kit, in Subjects with Hypertension.
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Trial now transitioned) SE (Ongoing) BE (Trial now transitioned) NL (Trial now transitioned) IE (Trial now transitioned) PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-002232-26 Sponsor Protocol Number: LERCA-GLOMERULAR Start Date*: 2004-11-04
    Sponsor Name:HOSPITAL 12 OCTUBRE
    Full Title: CHANGES IN GLOMERULAR HEMODINAMICS PARAMETERS IN HIPERTENSIVE PATIENTS AFTER TREATMENT WITH LERCANIDIPINE
    Medical condition: HYPERTENSION
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004846-17 Sponsor Protocol Number: STH 14399 Start Date*: 2007-03-16
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: A randomised, placebo controlled trial of the efficacy of the addition of spironolactone to modern antihypertensive treatment regimes in patients with resistant hypertension.
    Medical condition: Resistant hypertension.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001404-14 Sponsor Protocol Number: QGC001-3QG2 Start Date*: 2021-08-17
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 3, Double-blind, Placebo-controlled and Open-label Efficacy and Long-term Safety Study of Firibastat (QGC001) Administered Orally, Once Daily, for Up to 48 Weeks in Patients with Difficult-...
    Medical condition: Treatment of patients with difficult-to-treat and/or treatment-resistant hypertension (HTN)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10036695 Primary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended) HU (Prematurely Ended) ES (Ongoing) CZ (Prematurely Ended) IT (Completed) NL (Prematurely Ended) BE (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-003535-20 Sponsor Protocol Number: CS8635-A-E303 Start Date*: 2009-04-07
    Sponsor Name:DAIICHI SANKYO EUROPE GmbH
    Full Title: A RANDOMISED, DOUBLE-BLIND, ADD-ON STUDY OF HYDROCHLOROTHIAZIDE IN SUBJECTS WITH MODERATE TO SEVERE HYPERTENSION NOT ACHIEVING TARGET BLOOD PRESSURE ON OLMESARTAN MEDOXOMIL/AMLODIPINE FIXED DOSE CO...
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) FR (Completed) BE (Completed) ES (Completed) AT (Completed) CZ (Completed) DK (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2019-004509-29 Sponsor Protocol Number: QGC001-3QG1 Start Date*: 2020-04-27
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 3, Double-blind, Placebo-controlled, Efficacy and Safety Study of Firibastat (QGC001) Administered Orally, Twice Daily, Over 12 Weeks in Difficult-to-treat/Resistant Hypertensive Subjects
    Medical condition: Treatment of hypertension (HTN) in difficult-to-treat and/or treatment resistant patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) PL (Completed) ES (Ongoing) CZ (Completed) HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2018-000036-96 Sponsor Protocol Number: CR0014 Start Date*: 2018-09-06
    Sponsor Name:Ablative Solutions, Inc.
    Full Title: A Phase 2, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System Kit, in Subjects with Hypertension, in the Absence of Antihypertensive Medications
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (GB - no longer in EU/EEA) DE (Completed) IE (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-000020-32 Sponsor Protocol Number: CV131-176 Start Date*: 2005-02-16
    Sponsor Name:Bristol Myers Squibb International Corporation
    Full Title: The Efficacy and Safety of Irbesartan/HCTZ Combination Therapy as First Line Treatment for Severe Hypertension
    Medical condition: Severe Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003182-16 Sponsor Protocol Number: A07329 Start Date*: 2005-08-26
    Sponsor Name:Addenbrooke's Hospital Trust
    Full Title: Blood Pressure Optimisation In Patients With Polycystic Kidney Disease And Hypertension By Rotation Through The Main Therapeutic Classes Of Antihypertensive Drugs.
    Medical condition: Polycystic kidney disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005344-95 Sponsor Protocol Number: 3004 Start Date*: 2012-06-15
    Sponsor Name:Steno Diabetes Center
    Full Title: Time course of the blood pressure lowering effect of liraglutide therapy in type 2 diabetes
    Medical condition: type 2 diabetes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000577-13 Sponsor Protocol Number: kajakbe191086 Start Date*: 2015-09-09
    Sponsor Name:Oslo University Hospital
    Full Title: Therapeutic effects of BNP in uncontrolled hypertensive patients 1
    Medical condition: Uncontrolled hypertension (UHT, i.e. blood pressure ≥ 150/90, or ≥ 150/85 mm Hg in diabetic patients) despite treatment with at least two different classes of antihypertensive medications.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-001283-10 Sponsor Protocol Number: NL80929.091.22 Start Date*: 2022-06-28
    Sponsor Name:Radboud University Medical Center
    Full Title: The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly
    Medical condition: Hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001061-17 Sponsor Protocol Number: CSPP100A2306 Start Date*: 2005-04-12
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 26 week, double-blind, randomized, multicenter, parallel group, active-controlled study comparing aliskiren to ramipril with optional addition of hydrochlorothiazide (HCTZ), followed by a 4 week ...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) DK (Completed) IS (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-000631-25 Sponsor Protocol Number: 2007-000631-25 Start Date*: 2010-06-08
    Sponsor Name:KAROLINSKA INSTITUTET
    Full Title: THE ANTITTHROMBOTIC EFFECTS OF DOXAZOSIN AND RAMIPRIL IN ESSENTIAL HYPERTENSION
    Medical condition: ESSENTIAL HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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