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Clinical trials for Arteriovenous malformations

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    7 result(s) found for: Arteriovenous malformations. Displaying page 1 of 1.
    EudraCT Number: 2011-000321-69 Sponsor Protocol Number: PHRCN10-Pr.DEVAUCHELLE Start Date*: 2014-03-06
    Sponsor Name:CHU Amiens
    Full Title: Evaluation prospective de l’efficacité du sirolimus (Rapamune) dans le traitement des malformations artério-veineuses superficielles
    Medical condition: Malformations artério-veineuses superficielles
    Disease: Version SOC Term Classification Code Term Level
    14.0 10010331 - Congenital, familial and genetic disorders 10003229 Arteriovenous malformations LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-003573-26 Sponsor Protocol Number: TRAMAV02092019 Start Date*: Information not available in EudraCT
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: Monocentric pilot trial evaluating efficacy of Trametinib in Arteriovenous Malformations that are refractory to standard treatments or for which standard treatment are contra-indicated
    Medical condition: Arteriovenous Malformations that are refractory to standard treatments or for which standard treatment are contra-indicated
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001455-37 Sponsor Protocol Number: 1331TMF Start Date*: 2011-12-21
    Sponsor Name:Department of Radiology, Oslo University Hospital, Norway
    Full Title: Prospective randomized interventional study. Compare the effect of bleomycin and Tetradecyl Sodium Sulphate (Fibrovein) in the treatment of venous malformations. Clinical neurological and neurophys...
    Medical condition: Venous malformation
    Disease: Version SOC Term Classification Code Term Level
    13.1 10010331 - Congenital, familial and genetic disorders 10047229 Venous malformation NOS LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001359-11 Sponsor Protocol Number: PHRN17-AM-TOPICAL/DR180115 Start Date*: 2019-02-22
    Sponsor Name:CHRU TOURS
    Full Title: 0.1% topical sirolimus in the treatment of cutaneous microcystic lymphatic malformations in children and adults: phase II, split-body randomized, double-blind, vehicle-controlled clinical trial
    Medical condition: Cutaneous microcystic lymphatic malformations (CMLM) in children and adults
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10003229 Arteriovenous malformations LLT
    Population Age: Children, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001530-33 Sponsor Protocol Number: DR190041 Start Date*: 2019-06-29
    Sponsor Name:CHRU TOURS
    Full Title: TOPical sirolimus in linGUal microkystic lymphatic malformation-TOPGUN
    Medical condition: Lingual microcystic lymphatic malformations (LMLM) in children and adults
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10003229 Arteriovenous malformations LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-020545-26 Sponsor Protocol Number: HHT-BA0801 Start Date*: 2008-12-09
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: BEVACIZUMAB, AN ANTI-ANGIOGENIC MONOCLONAL ANTIBODY EFFECTIVE FOR PREVENTION OF HEMORRHAGING IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT): POSSIBLE REGRESSION OF VISCERAL ARTERIOVEN...
    Medical condition: HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005329 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003022-92 Sponsor Protocol Number: 9785-CL-0403 Start Date*: 2014-04-29
    Sponsor Name:Astellas Pharma Global Development, Inc.
    Full Title: A Multicenter, Single-Arm, Open-Label, Post-Marketing Safety Study to Evaluate the Risk of Seizure Among Subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated with Enzalutam...
    Medical condition: Medical condition: metastatic castration-resistant prostate cancer (mCRPC)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036909 Prostate cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Completed) DE (Completed) HU (Completed) GB (Completed) BE (Completed) FI (Completed) IT (Completed) CZ (Completed) GR (Completed) ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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