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Clinical trials for Brain imaging

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    874 result(s) found for: Brain imaging. Displaying page 1 of 44.
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    EudraCT Number: 2010-022772-31 Sponsor Protocol Number: 20100812v2 Start Date*: 2011-02-09
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Psychiatrie und Psychotherapie
    Full Title: Brain Network Dysfunction as a Model for Schizophrenia: Connectivity Alterations using Ketamine and pharmacological Magnetic Resonance Imaging
    Medical condition: Quantify changes of resting-state functional connectivity in response to Esketamine in healthy volunteers.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10029817 Nuclear magnetic resonance imaging brain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003618-18 Sponsor Protocol Number: M10-897 Start Date*: 2013-04-19
    Sponsor Name:Abbott GmbH & Co. KG
    Full Title: A Randomized, Double-Blind, Phase 2, Dose-Ranging Study to Evaluate the Safety and Efficacy of Veliparib and Whole Brain Radiation Therapy Versus Placebo and Whole Brain Radiation Therapy in Su...
    Medical condition: Brain metastases from NSCLC
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006128 Brain metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) BE (Completed) CZ (Completed) FI (Completed) ES (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-005693-31 Sponsor Protocol Number: 312021 Start Date*: 2008-03-04
    Sponsor Name:BAYER
    Full Title: Contrast-enhanced MRI examination of cerebral neoplastic enhancing lesions: comparison of diagnostic efficacy of Gd-DOTA 0.5 M and gadobutrol 1.0 M at 0.1 mmol Gd/kg body weight: Intra-individual ...
    Medical condition: patients with cerebral neoplastic lesions
    Disease: Version SOC Term Classification Code Term Level
    6.1 10006131 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-004244-37 Sponsor Protocol Number: 13HH1824 Start Date*: 2014-02-21
    Sponsor Name:Imperial College London | Imperial College NHS Healthcare Trust
    Full Title: The control of brain networks after traumatic brain injury: a neuroimaging and neuropsychological study of dopamine and cognition
    Medical condition: Traumatic Brain Injury
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-006301-10 Sponsor Protocol Number: MAGNA Start Date*: 2012-05-10
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Perioperative Magnesium Sulphate as a cerebral protector in neurosurgical patients
    Medical condition: Patient who are going to be under cerebral parenchyma resection, due to epilepsy or tumor
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10039911 Seizures (incl subtypes) HLGT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006153 Brain tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-006724-35 Sponsor Protocol Number: fMRI-CA_2008 Start Date*: 2008-09-08
    Sponsor Name:CMIV
    Full Title: Functional MRI after administration of Gd-based blood pool contrast agents
    Medical condition: This study aims to investigate the possibility to obtain higher functional contrast and better spatial assessment in contrast enhanced functional Magnetic Resonance Imaging (fMRI) as compared to st...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029820 Nuclear magnetic resonance imaging gadolinium-enhanced LLT
    9.1 10029817 Nuclear magnetic resonance imaging brain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011824-79 Sponsor Protocol Number: 91686125 Start Date*: 2009-11-03
    Sponsor Name:Academic Medical Center
    Full Title: Effects of fluoxetine on the outgrowth of the serotonergic system
    Medical condition: We investigate whether the effects fluoxetine (Prozac®) on the outgrowth of the serotonergic system are dependent on age. In a 16 week multicenter randomized, double-blind, placebo controlled trial...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10056941 MRI brain LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-004512-58 Sponsor Protocol Number: INV-GEM-0200-I Start Date*: 2020-08-17
    Sponsor Name:Technische Universität München, Fakultät für Medizin
    Full Title: Comparison of Fluorescein-INtra-VItal microscopy Versus conventional frozen section diagnosis for intraOperative histopathological evaluation
    Medical condition: Intracranial tumor
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10006153 Brain tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003804-15 Sponsor Protocol Number: SGMCBM Start Date*: 2023-12-19
    Sponsor Name:Leiden University Medical Center
    Full Title: A FEASIBILITY STUDY OF SGM-101, A FLUOROCHROME-LABELED ANTI-CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY FOR THE INTRAOPERATIVE DETECTION OF COLORECTAL BRAIN METASTASES
    Medical condition: Colorectal brain metastases
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055093 Brain cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-002328-24 Sponsor Protocol Number: BRAIN Start Date*: 2015-09-04
    Sponsor Name:UZ Brussel
    Full Title: Evaluation of 68GaNOTA-Anti-HER2 VHH1 uptake in brain metastasis of cancer patients
    Medical condition: brain metastasis lesions from potential HER2 cancer patients
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004189-13 Sponsor Protocol Number: 1 Start Date*: 2012-02-23
    Sponsor Name:Medizinische Universität Wien
    Full Title: ASSESSMENT OF MULTIDRUG RESISTANCE IN BREAST CANCER AND LOW GRADE GLIOMA PATIENTS WITH [11C]TARIQUIDAR PET. A PILOT STUDY
    Medical condition: Prospective cohort diagnostic test accuracy study in 30 breast cancer patients scheduled for neoadjuvant chemotherapy (15 of which with Pgp-positive and 15 with Pgp-negative tumors) and 10 low grad...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004864 10006153 Brain tumor LLT
    18.1 100000004864 10006192 Breast cancer NOS LLT
    Population Age: Adults Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-004990-10 Sponsor Protocol Number: MF/UME01 Start Date*: 2012-01-09
    Sponsor Name:Sahlgrenska Academy
    Full Title: Double-blind placebo controlled study of the effects of OSU6162 on chronic fatigue in patients who suffered a mild traumatic brain injury
    Medical condition: Mental fatigue after traumatic brain injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013030-25 Sponsor Protocol Number: GE-067-007 Start Date*: 2010-05-12
    Sponsor Name:GE Healthcare Ltd. and its Affiliates
    Full Title: A Principal Open-Label Study to Compare the Brain Uptake of [18F]flutemetamol with Brain Amyloid Levels Determined Post-Mortem
    Medical condition: The subjects have a short life expectancy. GE-067-007 will determine the level of association between brain uptake of (18F)flutemetamol and brain amyloid levels. Assessments will be based on analy...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10048669 Terminal state LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006135-29 Sponsor Protocol Number: PH-107 Start Date*: 2012-09-03
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: PHASE IV, DOUBLE-BLIND, MULTI-CENTER, RANDOMIZED, CROSSOVER STUDY TO COMPARE 0.1 mmol/kg OF PROHANCE® WITH 0.1 mmol/kg OF GADOVIST®/GADAVIST™ IN MAGNETIC RESONANCE IMAGING (MRI) OF THE BRAIN (TRUTH)
    Medical condition: Have confirmed or are highly suspected of brain disease likely to enhance as determined by the following: clinical/neurological symptomatology; diagnostic testing, such as CT or previous MRI exam...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10029820 Nuclear magnetic resonance imaging gadolinium-enhanced LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000206-23 Sponsor Protocol Number: MH-123 Start Date*: 2009-09-15
    Sponsor Name:BRACCO IMAGING
    Full Title: PHASE IV, DOUBLE-BLIND, MULTI-CENTER, RANDOMIZED, CROSSOVER STUDY TO COMPARE 0.1 mmol/kg OF MULTIHANCE WITH 0.1 mmol/kg OF GADOVIST IN MAGNETIC RESONANCE IMAGING (MRI) OF THE BRAIN (MERIT)
    Medical condition: Subjects with confirmed or highly suspected brain tumor(s) (primary or secondary)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029818 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2017-003381-27 Sponsor Protocol Number: 100045 Start Date*: 2018-09-24
    Sponsor Name:CEA
    Full Title: Study in 18F-DPA714 PET to better locate preoperatively the epileptic focus to resect in drug-resistant partial epilepsy
    Medical condition: Brain imaging on people with partial pharmaco resistant epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-001084-10 Sponsor Protocol Number: GEP 02/0801 Start Date*: 2008-11-21
    Sponsor Name:FNCLCC
    Full Title: A multicenter phase II clinical trial assessing the efficacy of the combination of lapatinib and capecitabine in patients with non pretreated brain metastasis from HER2 positive breast cancer.
    Medical condition: Patient with non penetrated brain metastasis from HER2 positive breast cancer.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006128 Brain metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018181-36 Sponsor Protocol Number: 09117 Start Date*: 2010-02-23
    Sponsor Name:University of Nottingham
    Full Title: Nitrous Oxide and Functional Magnetic Resonance Imaging to investigate cerebral regional blood flow, cerebral metabolism and neuronal activity.
    Medical condition: This is part of a series of studies investigating the potential therapeutic use of low dose nitrous oxide in the treatment of cerebral vasospasm, a condition which occurs following brain injury and...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002845-39 Sponsor Protocol Number: Infmed1 Start Date*: 2019-10-02
    Sponsor Name:Aalborg University Hospital
    Full Title: Partial oral antibiotic treatment for bacterial brain abscess: An open-label randomised non-inferiority trial (ORAL)
    Medical condition: Brain abscess
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10006105 Brain abscess PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned) FR (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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