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Clinical trials for CCR5

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    38 result(s) found for: CCR5. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-007208-28 Sponsor Protocol Number: TROPISMVC Start Date*: 2009-05-06
    Sponsor Name:Asociación para el Estudio de las Enfermedades Infecciosas
    Full Title: Estudio comparativo de dos métodos para predecir el uso de co-receptores por el virus de la inmunodeficiencia 1 (HIV-1): el ensayo fenotípico (Trofile ESTA®) y la respuesta virológica a corto plazo...
    Medical condition: Infección por el Virus de la Inmunodeficiencia Humana tipo-1 (VIH-1). El antirretroviral maraviroc pertenece a un grupo de medicamentos llamados antagonistas del CCR5 e impide la entrada del VIH-1 ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006769-95 Sponsor Protocol Number: SSAT030 Start Date*: 2009-06-02
    Sponsor Name:St Stephen's Aids Trust
    Full Title: A Randomised, Placebo Controlled, Phase IV, Safety and Exploratory Immunogenicity Study into the Impact of Maraviroc, an Orally Administered CCR5 Inhibitor, on the Intensification of Immune Functio...
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023625-38 Sponsor Protocol Number: JF003 Start Date*: 2012-11-13
    Sponsor Name:Guy's and St Thomas' NHS Foundation Trust
    Full Title: Investigating the effect of Maraviroc on microbial translocation in HIV-1 infected individuals who are receiving antiretroviral therapy
    Medical condition: HIV
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10068341 HIV-1 infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011538-93 Sponsor Protocol Number: Maraviroc –switch Start Date*: 2010-06-07
    Sponsor Name:Imperial College London
    Full Title: A prospective, randomised study to access safety, changes in platelet reactivity, plasma cardiac biomarkers and metabolic parameters over 48 weeks in HIV-1 infected subjects undergoing a switch in...
    Medical condition: HIV
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000799-32 Sponsor Protocol Number: PROTEST Start Date*: 2011-06-08
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Use of genotypic HIV-1 tropism testing in proviral DNA to guide CCR5 antagonist treatment in subjects with undetectable HIV-1 viremia
    Medical condition: Human immunodeficiency virus (HIV) infection.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10008922 Chronic infection with HIV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-014602-33 Sponsor Protocol Number: CH-2009.01 Start Date*: 2010-06-03
    Sponsor Name:Centre Hospitalier Intercommunal de Toulon - La Seyne sur Mer
    Full Title: IMPACT D’UNE INTENSIFICATION THERAPEUTIQUE PAR INHIBITEUR D’INTEGRASE +/- INHIBITEUR DE CCR5 SUR LE RESERVOIR LYMPHOÏDE DU VIH-1 CHEZ DES PATIENTS AU STADE CHRONIQUE DE L’INFECTION
    Medical condition: Infection à VIH-1
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006286-80 Sponsor Protocol Number: MRV-Study-08 Start Date*: 2009-02-25
    Sponsor Name:Daniel Podzamczer Palter
    Full Title: Evaluación de los niveles farmacológicos de Maraviroc en Líquido Cefalorraquídeo (LCR) y semen en sujetos infectados por el VIH.
    Medical condition: Infección por VIH
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015113-44 Sponsor Protocol Number: NEAT001 Start Date*: 2010-05-19
    Sponsor Name:ANSR
    Full Title: Ensayo abierto, aleatorizado, de dos años de duración, en el que se comparan dos regímenes de primera línea en sujetos infectados por el VIH que no han recibido tratamiento antirretroviral previo: ...
    Medical condition: Infección por el virus de la inmunodeficiencia humana
    Disease: Version SOC Term Classification Code Term Level
    11 10068341 Infección por VIH 1 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FR (Completed) SE (Completed) IE (Completed) DK (Completed) PT (Completed) AT (Completed) DE (Completed) GB (Completed) PL (Completed) IT (Completed) BE (Completed) NL (Completed) HU (Completed) GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022293-14 Sponsor Protocol Number: ANRS146OPTIMAL Start Date*: 2012-08-22
    Sponsor Name:Inserm-ANRS
    Full Title: Optimized Phase III Trial of Immuno-stimulation with Maraviroc, a CCR5 antagonist, combined with Anti Retroviral Therapy (cART) in advanced, Late diagnosed HIV-1 infected patients with an AIDS-defi...
    Medical condition: HIV infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003995-21 Sponsor Protocol Number: ERRADVIH-01 Start Date*: 2007-12-03
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal
    Full Title: Estudio piloto del efecto de un antagonista de co-receptores CCR5 sobre la latencia y el reservorio del VIH-1 en pacientes que reciben tratamiento antirretroviral de gran actividad
    Medical condition: VIH
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020192 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004692-22 Sponsor Protocol Number: NA Start Date*: 2015-11-19
    Sponsor Name:University of Torino
    Full Title: MARAT Study “Pharmacokinetics of MARaviroc and boosted ATazanavir dual regimen in stable HIV-infected patients”
    Medical condition: HIV infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018709-12 Sponsor Protocol Number: OSCAR Start Date*: 2010-09-23
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Optimizing Susceptibility to CCR5 Antagonist Response
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008922 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016480-11 Sponsor Protocol Number: 2009HD/01 Start Date*: 2009-12-28
    Sponsor Name:P Pierre Dellamonica
    Full Title: “No Nuc, No Boost” : A phase 2 pilot study of simplification by Maraviroc-Raltegravir following 6 months of treatment with Maraviroc-Raltegravir-Tenofovir-Emtricitabine in naive patients infected b...
    Medical condition: HIV naïve patients, CCR5 tropism, with CD4 > 200/mm3 and HIV RNA < 100 000 copy/ml.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020192 HIV-1 LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001779-20 Sponsor Protocol Number: A4001029 Start Date*: 2005-02-02
    Sponsor Name:Pfizer Limited
    Full Title: A multicentre, randomised, double-blind, placebo-controlled trial of novel CCR5 antagonist, UK-427,857, in comination with optimised background therapy versus optimised background therapy alone for...
    Medical condition: UK-427,857 is an antagonist of the human chemokine receptor, and is intended to help prevent the development and progression of AIDS in individuals HIV-1 positive.
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) ES (Completed) BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006821-15 Sponsor Protocol Number: A7691009 Start Date*: 2007-06-21
    Sponsor Name:Pfizer Inc., 235 East 42nd Street, New York, NY 10017
    Full Title: A RANDOMISED, DOUBLE-BLIND (SPONSOR-OPEN), PLACEBO-CONTROLLED, MULTICENTRE STUDY IN ASYMPTOMATIC HIV-INFECTED PATIENTS TO INVESTIGATE THE PHARMACODYNAMICS, PHARMACOKINETICS, SAFETY AND TOLERATION ...
    Medical condition: Human Immunodeficiency Virus (HIV) infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000807 Acute HIV infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003865-33 Sponsor Protocol Number: CCR100136 Start Date*: 2005-02-03
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Phase IIb, 96 week, randomized, open-label, multicenter, parallel group, repeat dose study to evaluate the safety, tolerability, pharmacokinetics and antiviral effect of different doses and regim...
    Medical condition: Treatment of HIV-1 infection
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) IT (Prematurely Ended) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001914-15 Sponsor Protocol Number: A4001026 Start Date*: 2008-02-07
    Sponsor Name:ViiV Healthcare UK Limited
    Full Title: A multicentre, randomised, double-blind, comparative trial of a novel CCR5 antagonist, UK427,857, in combination with zidovudine/lamivudine versus efavirenz in combination with zidovudine/lamivudin...
    Medical condition: UK-427,857 is an antagonist of the human chemokine receptor, and is intended to help prevent the development and progression of AIDS in indivuduals HIV-1 positive.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000649-11 Sponsor Protocol Number: SSAT046 Start Date*: 2012-08-22
    Sponsor Name:St Stephen's Aids Trust
    Full Title: A phase IV, open-label, single centre, single-arm, pilot study to assess Cerebrospinal fluid INflammatory markers after Addition of Maraviroc to MONotherapy darunavir/ritonavir – The CINAMMON Study...
    Medical condition: HIV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-003501-10 Sponsor Protocol Number: 3883 Start Date*: 2013-04-24
    Sponsor Name:Vall d'Hebron Institut de Recerca (VHIR)
    Full Title: Efficacy of dual antiretroviral treatment with maraviroc plus ritonavir-boosted darunavir in early rescue therapy in patients with HIV-1 infection: pilot, multicenter, randomized, controlled and op...
    Medical condition: Adult patients with HIV-1 infection that present virologic failure to first-line antiretroviral treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011171-76 Sponsor Protocol Number: ANRS 145 Start Date*: 2009-05-25
    Sponsor Name:Agence nationale de recherches sur le sida et les hépatites virales. ANRS.
    Full Title: Etude pilote évaluant l’intérêt d’une intensification par maraviroc (Celsentri®) chez des patients infectés par le VIH-1 présentant une restauration immunitaire insuffisante malgré une charge viral...
    Medical condition: Infection VIH
    Disease: Version SOC Term Classification Code Term Level
    11.1 10020161 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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