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Clinical trials for Cardioplegia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    14 result(s) found for: Cardioplegia. Displaying page 1 of 1.
    EudraCT Number: 2017-005144-14 Sponsor Protocol Number: 01-CARDIONIDO Start Date*: 2018-04-12
    Sponsor Name:Dr. Forteza Gil
    Full Title: Comparative study of two types of cardioplegia during cardiac surgery in the adult patient
    Medical condition: Cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015779-28 Sponsor Protocol Number: Start Date*: 2009-12-11
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: A single-centre randomised controlled trial of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients having isolated coronary artery bypass grafting (CABG) or ao...
    Medical condition: Myocardial injury after CABG or AVR surgery using cardiopulmonary bypass
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002701-59 Sponsor Protocol Number: IIBSP-CAR-2018-71 Start Date*: 2019-04-12
    Sponsor Name:Institut de Recerca Hospital de la Santa Creu i Sant Pau
    Full Title: Randomized, open and multi-center clinical trial to compare the efficacy and safety of Buckberg vs Del Nido cardioplegia in isolated aortic valve replacement
    Medical condition: Myocardial protection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001923-22 Sponsor Protocol Number: ADENOSINE-1 Start Date*: 2015-12-16
    Sponsor Name:Amphia Ziekenhuis
    Full Title: The effect of adenosine on myocardial protection in intermittent warm blood cardioplegia: a randomized placebo-controlled trial
    Medical condition: Post-operative cardiac damage in patients scheduled for minimal invasive, port-access operations
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006480-23 Sponsor Protocol Number: 10,176 Start Date*: 2007-10-12
    Sponsor Name:University Hospitals of Leicester
    Full Title: Autologous Bone Marrow-Derived Cells for Cardioprotection During Heart Surgery
    Medical condition: Improvement of cardioprotection during elective coronary artery bypass graft surgery using the patients own bone marrow cells.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002643-10 Sponsor Protocol Number: HCA-2011_1 Start Date*: 2012-01-17
    Sponsor Name:Heart Center Co. Tampere University Hospital
    Full Title: Intracoronary administration of levosimendan in cardiac surgery patients
    Medical condition: Dysfunction after opening of aortic cross-clamp in patients undergoing aortic valve and coronary artery bypass (AVR+CABG) operation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003776-40 Sponsor Protocol Number: CL-N-CSM-AV-III/05/12 Start Date*: 2013-11-08
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: A Prospective Randomized Double Blind Multicenter Phase III Study Comparing two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N versus Custodiol
    Medical condition: Patients with aortic valve disease and has to undergo aortic valve surgery +/- bypass surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-003638-38 Sponsor Protocol Number: FIM-SEV-2022-01 Start Date*: 2023-04-10
    Sponsor Name:FIMABIS
    Full Title: CARDIOPROTECTIVE-NEPHROPROTECTIVE EFFECTS OF SEVOFLURAN IN COMPARISON WITH PROPOFOL IN DOUBLE VALVULAR SURGERY. USE OF SEVOFLURANE AS A PILLAR OF PROTECTION IN EXTRACORPOREA CIRCULATION AND POSTOPE...
    Medical condition: DOBLE VALVE SURGERY
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10007615 Cardiac valve therapeutic procedures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020677-17 Sponsor Protocol Number: ALMED-09-C3-026 Start Date*: 2011-11-16
    Sponsor Name:Air Liquide Santé International
    Full Title: Efficacy and safety of xenon anaesthesia compared to sevoflurane anaesthesia and total intravenous anaesthesia for on-pump coronary artery bypass graft surgery: a randomised, three-arm, single-blin...
    Medical condition: General anesthesia for on pump coronary artery bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10006894 CABG LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005992-81 Sponsor Protocol Number: CL-N-CSM-III/01/08 Start Date*: 2011-03-21
    Sponsor Name:Dr. F. Köhler Chemie GmbH
    Full Title: A Prospective Randomized Double Blind Multicenter Phase III Study Comparing two Methods of Cardioplegia in Coronary Artery Bypass Surgery Custodiol-N versus Custodiol
    Medical condition: The study population will be selected from both genders with coronary artery disease (CAD) who are to undergo cardiopulmonary bypass for coronary artery bypass surgery. The ratio of incidence for b...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001382-26 Sponsor Protocol Number: HCS-2014-2 Start Date*: 2014-06-09
    Sponsor Name:TAYS Sydänsairaala
    Full Title: Adenosine in initial cardioplegia
    Medical condition: Coronary artery disease, aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    16.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2022-001795-34 Sponsor Protocol Number: CL-N-HTX-Paed-II/10/20 Start Date*: 2023-01-30
    Sponsor Name:Dr. Franz Köhler Chemie GmbH
    Full Title: A prospective randomized single blind multicenter phase II study of organ perfusion with Custodiol-N compared with Custodiol in heart transplantation in children
    Medical condition: Preservation of hearts prior to heart transplantation in children
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004881-16 Sponsor Protocol Number: P05633 Start Date*: 2009-06-10
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: The Effect of Acadesine on Clinically Significant Adverse Cardiovascular and Cerebrovascular Events in High-Risk Subjects Undergoing Coronary Artery Bypass Graft (CABG) Surgery Using Cardiopulmonar...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) ES (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023552-90 Sponsor Protocol Number: BQ123CPBP2010 Start Date*: 2011-05-05
    Sponsor Name:Medizinische Universität Wien, Abteilung für Herzchirurgie
    Full Title: Short-term endothelin A receptor blockade in patients with on-pump coronary artery bypass grafting
    Medical condition: aorto-coronary bypass surgery in patients with coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011077 Coronary artery bypass LLT
    12.1 10011085 Ischaemic coronary artery disorders HLT
    12.1 10011090 Coronary artery surgery LLT
    12.1 10011098 Coronary bypass LLT
    12.1 10049887 Coronary revascularisation LLT
    12.1 10054366 Coronary revascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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