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Clinical trials for Cerebral blood flow

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    104 result(s) found for: Cerebral blood flow. Displaying page 1 of 6.
    1  2  3  4  5  6  Next»
    EudraCT Number: 2018-003286-34 Sponsor Protocol Number: CHUBX2017/22 Start Date*: 2019-03-05
    Sponsor Name:CHU de Bordeaux
    Full Title: In vivo involvement of the cholinergic and dopaminergic systems in the pathophysiology of apathy.
    Medical condition: Apathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10002942 Apathy PT
    20.0 100000004852 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-002457-30 Sponsor Protocol Number: 13.0099 Start Date*: 2013-09-13
    Sponsor Name:St George's University of London
    Full Title: An open label randomised controlled trial investigating the effect of donepezil on regional cerebral blood flow in adults with aneurysmal subarachnoid haemorrhage.
    Medical condition: Aneurysmal subarachnoid haemorrhage Cerebral vasospasm Ischaemic stroke
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10047164 Vasospasm cerebral LLT
    16.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    16.0 10029205 - Nervous system disorders 10055845 Haemorrhage subarachnoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007094-23 Sponsor Protocol Number: Nitrous oxide protocol V5 Start Date*: 2008-10-09
    Sponsor Name:University of Nottingham
    Full Title: Nitrous oxide and cerebral vasodilatation: a dose-response study in healthy volunteers
    Medical condition: The study will be conducted in healthy volunteers. I will evaluate the effects of inhaled concentrations of nitrous oxide, ranging from 0% to 50%, on cerebral blood flow and cerebral vascular tone ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008597-31 Sponsor Protocol Number: Start Date*: 2010-08-17
    Sponsor Name:Malmoe University Hospital
    Full Title: Comparative study to evaluate the effects of racemic ketamin versus s-ketamine on cerebral blood flow, blood volume and metabolism
    Medical condition: Racemic ketamine is used for sedation, analgesia and anesthesia to patients in various forms of circulatory compromise ie shock. The enantiomere S-ketamine has not been compared regarding cerebral ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018181-36 Sponsor Protocol Number: 09117 Start Date*: 2010-02-23
    Sponsor Name:University of Nottingham
    Full Title: Nitrous Oxide and Functional Magnetic Resonance Imaging to investigate cerebral regional blood flow, cerebral metabolism and neuronal activity.
    Medical condition: This is part of a series of studies investigating the potential therapeutic use of low dose nitrous oxide in the treatment of cerebral vasospasm, a condition which occurs following brain injury and...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022874-15 Sponsor Protocol Number: 10084 Start Date*: 2010-11-08
    Sponsor Name:University of Nottingham
    Full Title: Comparison of 30% nitrous oxide with therapeutic dose nimodipine on cerebral and systemic vascular physiology
    Medical condition: This is part of a series of studies investigating the potential therapeutic use of low dose nitrous oxide in the treatment of cerebral vasospasm, a condition which occurs following brain injury and...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-001283-10 Sponsor Protocol Number: NL80929.091.22 Start Date*: 2022-06-28
    Sponsor Name:Radboud University Medical Center
    Full Title: The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly
    Medical condition: Hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001279-19 Sponsor Protocol Number: SONAS2018 Start Date*: 2019-08-19
    Sponsor Name:BURL Concepts, Inc.
    Full Title: Evaluation of the SONAS® ultrasound device for the assessment of bilateral cerebral perfusion in subjects with acute stroke
    Medical condition: Acute large vessel occlusion (LVO) stroke (NIHSS score: ≥ 10)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-001235-20 Sponsor Protocol Number: 14.0189 Start Date*: 2015-06-05
    Sponsor Name:St George's University of London
    Full Title: Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease
    Medical condition: PARTICIPANTS WITH EVIDENCE OF CEREBRAL SMALL VESSEL DISEASE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-004669-24 Sponsor Protocol Number: 8103 Start Date*: 2009-01-02
    Sponsor Name:Research Innovation Services, University of Nottingham
    Full Title: Nitrous Oxide and Cerebral Autoregulation
    Medical condition: This study is being conducted to evaluate the effects of inhaled concentrations of 20%, 30% and 40% Nitrous Oxide on cerebral autoregulation in healthy volunteers using transcranial doppler ultraso...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-002008-15 Sponsor Protocol Number: NL65095.041.18 Start Date*: 2018-06-08
    Sponsor Name:University Medical Center Utrecht
    Full Title: Optimal cerebral perfusion after an extracranial-intracranial bypass: should we increase blood pressure or cardiac output?
    Medical condition: Patients with an indication for an extracranial-intracanial bypass (e.g. Moya Moya Disease, occluded carotid artery, giant aneurysm)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10029999 Occlusion carotid LLT
    20.1 100000004852 10002333 Aneurysm cerebral LLT
    20.1 100000004852 10002337 Aneurysm intracranial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001557-27 Sponsor Protocol Number: A9951024 Start Date*: 2014-01-13
    Sponsor Name:Pfizer Inc. 235 East 42nd Street, New York, NY 10017
    Full Title: A PHASE 2, RANDOMIZED, DOUBLE BLIND PLACEBO CONTROLLED TRIALTO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND EFFICACY OF PF-04360365 (PONEZUMAB) IN ADULT SUBJECTS WITH PROBABLE CEREBRAL A...
    Medical condition: Cerebral Amyloid Angiopathy (CAA)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10068044 Cerebral amyloid angiopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-000534-20 Sponsor Protocol Number: THAM05 Start Date*: 2005-03-15
    Sponsor Name:Addenbrooke's Hospital NHS Foundation Trust
    Full Title: Influence of brain tissue pH regulation on cerebral oxygenation and metabolism in patients with severe traumatic brain injury.
    Medical condition: Severe traumatic brain injury
    Disease:
    Population Age: Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008143-24 Sponsor Protocol Number: gas alogenati Start Date*: 2009-02-12
    Sponsor Name:AZIENDA OSPEDALIERA SAN GERARDO DI MONZA
    Full Title: Inhalatorial sedation in patient with SAH versus conventional intravenus sedation
    Medical condition: sub-arachnoid haemorrage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004139-74 Sponsor Protocol Number: PB1 Start Date*: 2005-04-20
    Sponsor Name:Neurologisk afdeling F
    Full Title: Parkinson’s Disease: PET scan and evaluation of memantines pharmacological effect. (Parkinsons sygdom bedømt med PET skanning, herunder memantins farmakologiske effekt.)
    Medical condition: Parkinson's Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001253-13 Sponsor Protocol Number: ROCHIMS Start Date*: 2017-08-23
    Sponsor Name:UZ Brussel
    Full Title: Does cerebral hypoperfusion play a role in reduced axonal metabolism and clinical disability in patients with multiple sclerosis ?
    Medical condition: Patients suffering relapsing- remitting multiple sclerosis will be investigated in this study, with an EDSS score less or equal to 4.0. Patients must be older than 18 years old. There must not be a...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004283-23 Sponsor Protocol Number: Emboli Inhibition Start Date*: 2006-05-05
    Sponsor Name:South Manchester University Hospital
    Full Title: An evaluation of potential therapies to inhibit cerebral emboli in dementia
    Medical condition: Alzheimer's Disease and Vascular Dementia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-002329-27 Sponsor Protocol Number: ETLAS-2 Start Date*: 2020-12-10
    Sponsor Name:Herlev Gentofte Hospital
    Full Title: Improving cerebral blood flow and cognition in patient with cerebral small vessel disease. The ETLAS-2 Trial.
    Medical condition: Cerebral small vessel disease and stroke.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10070879 Cerebral small vessel ischemic disease LLT
    22.1 10029205 - Nervous system disorders 10076994 Lacunar stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000586-33 Sponsor Protocol Number: 19-PP-15 Start Date*: 2021-07-21
    Sponsor Name:CHU de Nice
    Full Title: Effect of molar sodium lactate infusion on cerebral hemodynamic in patients with severe subarachnoid hemorrhage: a multicenter double-blind randomized controlled study
    Medical condition: Subarachnoid hemorrhage caused by rupture of cerebral aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001863-35 Sponsor Protocol Number: THAM Start Date*: 2016-06-21
    Sponsor Name:Universitätsklinik für Klinische Pharmakologie, Medizinische Universität Wien
    Full Title: Effects of Tromethamine on Cerebral Oxygenation and Metabolism in Patients Suffering Intractable Intracranial Hypertension – an exploratory study.
    Medical condition: Critically ill patients (SAH, ICB, AVM bleedings, malignant MCA infarcts) under sedation and mechanical ventilation in need of multimodality monitoring, including brain tissue oxygen monitoring and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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