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Clinical trials for Cold Sore

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44379   clinical trials with a EudraCT protocol, of which   7391   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    34 result(s) found for: Cold Sore. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2006-004015-21 Sponsor Protocol Number: CA-P-3978-01 Start Date*: 2006-08-31
    Sponsor Name:Johnson & Johnson Consumer and Personal Products Worldwide
    Full Title: Randomized Clinical Study Comparing Compeed Cold Sore Patch to Zovirax Cream 5% in the Treatment of Herpes Labialis
    Medical condition: Herpes Labialis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019942 Herpes labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004316-31 Sponsor Protocol Number: FPP4-DE-401 Start Date*: 2009-02-23
    Sponsor Name:Novartis Consumer Health S.A.
    Full Title: A randomised, double-blind, vehicle controlled, single centre, parallel group, comparative study of the efficacy of penciclovir 10 mg/g (1%) cream in preventing the appearance of classical lesions ...
    Medical condition: Cold Sores caused by the herpes simplex virus (HSV) type 1.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049352 Cold sores lip LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002135-26 Sponsor Protocol Number: 4PH/2011/002 Start Date*: 2012-02-16
    Sponsor Name:AESCULAPIUS FARMACEUTICI S.R.L.
    Full Title: Efficacy and Safety of Acyclovir 5 Lipstick (Contra) in Treatment of Skin Infections Provoked by Herpes Simplex. A Randomised, Double-blind, Placebo Controlled, Parallel Group Study.
    Medical condition: History of recurrent herpes labialis with at least 3 recurrences during the past 12 months and typically (>50% of episodes) associated with prodromal symptoms
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10019942 Herpes labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001384-60 Sponsor Protocol Number: C2380329 Start Date*: 2005-07-14
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: An exploratory, observational cohort study investigating commercially available treatments which may reduce the scab stage of recurrent herpes labialis
    Medical condition: Recurrent herpes labialis (RHL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002213-13 Sponsor Protocol Number: 6 BT Start Date*: 2006-09-28
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: A Phase I/II, Randomised, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Systemic Absorption and Dihydropyrimidine Dehydrogenase (DPD) Enzyme Activity Following Re...
    Medical condition: Herpes Simplex Labialis (HSL)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019942 Herpes labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021144-17 Sponsor Protocol Number: EA10-01-998 Start Date*: 2011-01-12
    Sponsor Name:Engelhard Arzneimittel GmbH & Co. KG
    Full Title: A phase III, multi-center, double-blind, randomized, vehicle controlled trial in a parallel-group design to evaluate the efficacy and safety of two formulations of Muxan containing 0.5 % or 1 % chl...
    Medical condition: Male or female patients, aged 12 years or older (first part of the trial: only patients aged 18 years or older), with an adequate history of recurrent herpes labialis and an acute episode of herpes...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019942 Herpes labialis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003559-32 Sponsor Protocol Number: CPO19001 Start Date*: 2023-03-16
    Sponsor Name:PharOS Pharmaceutical Oriented Services Single Member Ltd.
    Full Title: A Phase III Prospective, Randomized, Multicenter, Double-Blind, Placebo-controlled clinical study to evaluate the efficacy and safety of fixed dose combination (FDC) product Ibuprofen/Paracetamol/P...
    Medical condition: Temporary relief of cold and flu symptoms, i.e. mild to moderate pain, sore throat, fever and nasal congestion
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10009851 Cold LLT
    21.1 100000004867 10022009 Influenza-like symptoms LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001637-41 Sponsor Protocol Number: A7801001 Start Date*: 2005-07-26
    Sponsor Name:Pfizer Consumer Healthcare cva/sca
    Full Title: A community pharmacy based investigation in the self-medication area Efficacy and safety of Sinutab® (Paracetamol (500mg)/Pseudoephedrine (30mg)) on subjects with nasal congestion accompanied by h...
    Medical condition: Medical rationale= Investigation of combination drug Sinutab in symptomatic relief of common cold with nasal symptoms. Community pharmacists are considered as local investigators including subjec...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000058-35 Sponsor Protocol Number: A7801002 Start Date*: 2006-04-26
    Sponsor Name:Pfizer Consumer Healthcare Comm. VA/SCA
    Full Title: A community pharmacy based investigation in the self-medication area Efficacy and safety of Sinutab® [Paracetamol (500mg) and Pseudoephedrine (30mg)] on subjects with nasal congestion accompanied ...
    Medical condition: The medical rationale = to investigate this combination drug in the symptomatic relief of common cold with nasal symptoms. The reduction of symptom severity may allow subjects receiving active medi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2020-000926-24 Sponsor Protocol Number: HTX101-03L Start Date*: 2020-08-17
    Sponsor Name:Heidelberg ImmunoTherapeutics
    Full Title: A Randomised, Double-Blind Phase II Trial of Topical HDIT101 versus Placebo in Patients with Chronic Recurrent HSV-1 Infection and Orolabial Lesion
    Medical condition: Chronic Herpes Simplex Virus-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10073933 Herpes simplex oral LLT
    22.0 100000004862 10082141 Herpes simplex labialis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000860-51 Sponsor Protocol Number: CASK0120 Start Date*: 2020-06-25
    Sponsor Name:Cassella-med GmbH & Co. KG
    Full Title: The effect of early administered cineole on the course of a common cold
    Medical condition: common cold
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004862 10010106 Common cold LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005797-31 Sponsor Protocol Number: 701004.01.007 Start Date*: 2008-08-14
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Efficacy and tolerability of EPs® 7630 film-coated tablets in patients (>=18 years old) with Acute Rhinopharyngitis (ARP)
    Medical condition: Adult patients suffering from Acute Rhinopharyngitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000938 Acute nasopharyngitis (common cold) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002058-96 Sponsor Protocol Number: SAN-0657 Start Date*: 2021-11-16
    Sponsor Name:Lek Pharmaceuticals d.d.
    Full Title: Efficacy and safety of the combination of acetylcysteine, paracetamol and phenylephrine for the treatment of common cold: a prospective, randomized, double-blind, controlled trial
    Medical condition: Common cold and flu-like infections
    Disease: Version SOC Term Classification Code Term Level
    22.1 100000004862 10010106 Common cold LLT
    20.1 100000004862 10000938 Acute nasopharyngitis (common cold) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012640-17 Sponsor Protocol Number: KJos/FIN Start Date*: 2009-12-10
    Sponsor Name:Swedish Herbal Institute
    Full Title: A randomized, controlled, parallel-group, double-blind study of the proprietary Kan Jang Oral Solution versus placebo in patients with non complicated respiratory tract infections (common cold).
    Medical condition: common cold
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006690-25 Sponsor Protocol Number: OTCS-CE-301 Start Date*: 2007-02-09
    Sponsor Name:Novartis Consumer Health SA
    Full Title: A Double-Blind, Randomized, Parallel Group, Placebo Controlled Study, Evaluating the Decongestant Effect, Time to Onset, Duration of Effect and Impact on Sleep and General Well-being of Otrivin F2 ...
    Medical condition: nasal congestion associated with the common cold
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010106 Common cold LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000057-31 Sponsor Protocol Number: ESTUAR001 Start Date*: 2012-03-19
    Sponsor Name:THERANOR sprl
    Full Title: Multicentre, randomised, double-blind, parallel, placebo-controlled study evaluating the efficacy and safety of Early Self-Treatment of viral Upper respiratory tract infections with homeopathic ora...
    Medical condition: Viral upper respiratory tract infections
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10022004 Influenza like illness PT
    14.1 10021881 - Infections and infestations 10010106 Common cold LLT
    14.1 10021881 - Infections and infestations 10000938 Acute nasopharyngitis (common cold) LLT
    14.1 10021881 - Infections and infestations 10046300 Upper respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004910-41 Sponsor Protocol Number: WellmuneElderlyStudy1.1 Start Date*: 2011-12-30
    Sponsor Name:University of Southampton
    Full Title: A Randomised Controlled Trial to assess a food supplement (baker’s yeast extract) to support immune function and prevent cold and flu symptoms in a 50 to 70 year old population
    Medical condition: We aim to assess the number and severity of Upper Respiratory Tract Infection(URTI)Symptoms reported by participants over a 90 day period commencing in January 2012 in 100 healthy 50-70 year olds p...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001720-36 Sponsor Protocol Number: BAY E 4465/11764 Start Date*: 2005-10-24
    Sponsor Name:BAYER
    Full Title: A pivotal, placebo controlled, phaseIII study to compare efficacy and tollerability of a fixed combination, containing 500 mg ASA and 30 mg Pseudoephedrine, in comparison to its single components i...
    Medical condition: Cold related pain/fever e.g. sore throat, headache, ear eache, sinus pressure and nasal congestion.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10028735 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000242-35 Sponsor Protocol Number: 18CT0003 Start Date*: Information not available in EudraCT
    Sponsor Name:E-Pharma Trento SpA
    Full Title: Randomized, double blind, double dummy, parallel-groups, clinical trial on efficacy and safety of ibuprofen/N-acetylcysteine fixed dose combination vs. individual components (ibuprofen and N-acetyl...
    Medical condition: symptomatic non-complicated upper respiratory tract infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10046309 Upper respiratory tract infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005207-42 Sponsor Protocol Number: 2005079 Start Date*: 2005-12-29
    Sponsor Name:Procter & Gamble Technical Centres Limited
    Full Title: A study to assess the efficacy of a combination of natural plant extracts in natural colds.
    Medical condition: Common Cold (nasopharyngitis), Upper Respiratory Tract Infection
    Disease: Version SOC Term Classification Code Term Level
    8.0 10028810 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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