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Clinical trials for Comparative medicine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44364   clinical trials with a EudraCT protocol, of which   7388   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    22 result(s) found for: Comparative medicine. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-004062-17 Sponsor Protocol Number: NEK/MD/0119 Start Date*: 2020-12-03
    Sponsor Name:Nekkar Lab srl
    Full Title: OPEN, COMPARATIVE STUDY TO EVALUATE THE PERFORMANCE AND SAFETY OF THE MEDICAL DEVICE MARIAL® IN ASSOCIATION WITH PROTON-PUMP INHIBITORS VERSUS PPI ALONE IN PATIENTS AFFECTED BY GASTROESOPHAGEAL REF...
    Medical condition: gastroesophageal reflux disease (GERD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004886-14 Sponsor Protocol Number: 2013092981 Start Date*: 2016-08-22
    Sponsor Name:Dep. Nuclear medicine, Odense university hospital
    Full Title: MET-PET-study - Comparative study of Tc-99m- sestamibi SPECT/ldCT with C-11-L-Methionin PET/diagnostic CT and theri ability to locate paratyroid adenomas preoperatively.
    Medical condition: Preoperative localisation of hyperfunctioning parathyroid tissue in suspected primary hyperparathyroidism.
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004860 10036693 Primary hyperparathyroidism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-001299-38 Sponsor Protocol Number: EMULIP Start Date*: 2004-11-26
    Sponsor Name:Metabolism and Nutrition Group of the SEMICYUC
    Full Title: Study prospective, multicenter, randomized, comparative, double blind, to evaluate two different lipidic emulsions in the total parenteral nutrition of the critic patient and their influence in the...
    Medical condition: Patients in whom the necessity is foreseen to receive metabolic total parenteral nutrition like nutritional support, during a minimum period of 7 days, because they can not to be fed by route enter...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004961-25 Sponsor Protocol Number: 2008/0827 Start Date*: 2008-12-03
    Sponsor Name:CHRU de Lille
    Full Title: ETUDE COMPARATIVE KETAMINE DOSE UNIQUE VERSUS KETAMINE BOLUS ET PERFUSION CONTINUE DANS LA PRISE EN CHARGE DE L’ANALGESIE DES DOULEURS TRAUMATIQUES DES MEMBRES EN MEDECINE D’URGENCE PREHOSPITALIERE
    Medical condition: Limbs peripheral traumatisms in prehospital emergency medicine
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001387-28 Sponsor Protocol Number: NL73559.091.20 Start Date*: 2020-06-22
    Sponsor Name:Radboud University Medical Center
    Full Title: 18F-PSMA-1007 PET to detect primary prostate cancer: a comparative study with mpMRI and correlation to histopathology.
    Medical condition: 75 patients with the suspicion on PCa (elevated PSA and/or abnormal digital rectal exam) will receive a PSMA-PET following mpMRI. 25 patients with PIRADS 1-2 (probably benign disease), 25 patients ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036921 Prostate carcinoma LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000472-40 Sponsor Protocol Number: CN138-169 Start Date*: 2005-08-10
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Comparative, Randomized, Open -Label, Multicenter Study on the Efficacy and Safety of Switch Treatment with Aripiprazole in Schizophrenic Out-patients who are Experiencing Insufficient Efficacy w...
    Medical condition: Schizophrenia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) HU (Completed) GB (Completed) AT (Completed) DE (Completed) CZ (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-001123-40 Sponsor Protocol Number: RENARD Start Date*: 2021-09-08
    Sponsor Name:Amsterdam UMC, VU University Medical Center
    Full Title: 18F-fluciclovine PET/CT and 18F-DCFPyL PET/CT in patients with biochemical recurrence of disease after radical prostatectomy: a prospective, single-centre, single-arm, comparative imaging trial
    Medical condition: Prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10036911 Prostate cancer recurrent PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-001811-16 Sponsor Protocol Number: PS21GAP Start Date*: 2022-12-19
    Sponsor Name:Princess Maxima Center for pediatric oncology
    Full Title: 68Ga-SATO in pediatric neuroblastoma patient; exploratory, safety, non-randomized, open label, comparative study
    Medical condition: Neuroblastoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029260 Neuroblastoma PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-004483-19 Sponsor Protocol Number: RRK5908 Start Date*: 2017-09-09
    Sponsor Name:University Hospitals Birmingham NHS Foundation Trust
    Full Title: A randomised controlled trial to assess the clinical and cost effectiveness of topical lactic acid gel for treating second and subsequent episodes of bacterial vaginosis
    Medical condition: Bacterial Vaginosis
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10004055 Bacterial vaginosis PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-006078-84 Sponsor Protocol Number: BS558 Start Date*: 2008-07-24
    Sponsor Name:Generics [UK] Ltd trading as Merck Generics
    Full Title: A two-way crossover, sequential-dose, double-blinded, double-dummy, multiple dose, pharmacodynamic, comparative study of fluticasone propionate, 500 μg and 1000 μg twice daily delivered via pressu...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2023-000156-38 Sponsor Protocol Number: 20230123SE Start Date*: 2023-05-04
    Sponsor Name:Semmelweis University, Department of Internal Medicine and Oncology
    Full Title: Value-based health economic comparative study of subcutaneous and intravenous trastuzumab-pertuzumab for HER-2 positive metastatic breast cancer based on patient reported outcomes.
    Medical condition: HER-2 positive advanced breast cancer, locally unresectable or metastatic breast cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006198 Breast cancer recurrent PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006201 Breast cancer stage III PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006202 Breast cancer stage IV PT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10055113 Breast cancer metastatic PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004572-62 Sponsor Protocol Number: MO40379-ACHILES-2017-12 Start Date*: 2018-04-21
    Sponsor Name:Norwegian University of Science and Technology, Department of Clinical and molecular medicine
    Full Title: A randomized phase II study comparing atezolizumab after concurrent chemo-radiotherapy with chemo-radiotherapy alone in limited disease small-cell lung cancer
    Medical condition: Limited disease small-cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041069 Small cell lung cancer limited stage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned) DK (Trial now transitioned) LT (Trial now transitioned) NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004184-79 Sponsor Protocol Number: NIAD-01 Start Date*: 2013-05-01
    Sponsor Name:Dermal Laboratories Limited
    Full Title: A placebo controlled evaluation of a developmental gel for the treatment of atopic eczema
    Medical condition: The medical condition to be investigated in this study is atopic eczema, also known as atopic dermatitis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10003641 Atopic eczema LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-003971-16 Sponsor Protocol Number: FEMODRIC Start Date*: 2021-06-07
    Sponsor Name:Fundació Assistencial Mútua Terrassa
    Full Title: A randomised, double-blind, comparative clinical trial of the effectiveness and tolerability of fentanyl in continuous parenteral perfusion versus on-demand bolus of morphine for the treatment of ...
    Medical condition: Refractory dyspnoea in patients hospitalised for acute decompensation of heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005777-20 Sponsor Protocol Number: TMP-1115_01 Start Date*: 2016-12-12
    Sponsor Name:Fraunhofer Gesellschaft for its Institute Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
    Full Title: Impact of concomitant Methotrexate on efficacy, safety and adherence of Ustekinumab-treatment in patients with active Psoriatic Arthritis (MUST-Study)
    Medical condition: active psoriatic arthritis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10037160 Psoriatic arthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000816-24 Sponsor Protocol Number: FRAN-03-001 Start Date*: 2004-10-28
    Sponsor Name:Abbott France
    Full Title: A Pilot, Open-Label, Randomized, Comparative Study of the Antiviral Efficacy of Lopinavir/Ritonavir Single-Drug Regimen versus Lopinavir/Ritonavir in Combination with Lamivudine/Zidovudine in Antir...
    Medical condition: HIV-1 Infection
    Disease: Version SOC Term Classification Code Term Level
    7.0 10020192 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000994-26 Sponsor Protocol Number: ISA-HC-NK Start Date*: 2021-01-15
    Sponsor Name:Karolinska Institutet
    Full Title: An open, randomised, controlled phase II trial of CellProtect in combination with Isatuximab antibody versus Isatuximab antibody alone as maintenance treatment in patients with Multiple Myeloma und...
    Medical condition: Multiple Myeloma
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000689-14 Sponsor Protocol Number: FINPROVE Start Date*: 2021-10-06
    Sponsor Name:Helsinki University Hospital
    Full Title: The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs to determine the Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile
    Medical condition: Patients with an advanced solid tumor for which standard treatment options no longer exist and with acceptable performance status and organ function with a potentially actionable variant as reveale...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-005120-16 Sponsor Protocol Number: 62638 Start Date*: 2018-11-02
    Sponsor Name:Amsterdam UMC, Location VUmc
    Full Title: Ulipristal versus standard surgical treatment in symptomatic uterine fibroids
    Medical condition: Uterine fibroids are very common during reproductive years in women. Minimally invasive treatments are emerging. Myomectomy is the gold standard, preferably laparoscpically, because it removes the ...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10046784 Uterine fibroids LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-001358-41 Sponsor Protocol Number: VERCLBP002 Start Date*: 2023-02-27
    Sponsor Name:Vertanical GmbH
    Full Title: Multicentre, randomized, open-label study to prove an additional benefit of the full-spectrum cannabis extract VER-01 over opioids in the treatment of patients with chronic non-specific low back pain.
    Medical condition: Chronic non-specific low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Temporarily Halted) CZ (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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