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Clinical trials for Conservative treatment

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    176 result(s) found for: Conservative treatment. Displaying page 1 of 9.
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    EudraCT Number: 2017-001249-28 Sponsor Protocol Number: MU2017/001 Start Date*: 2019-05-21
    Sponsor Name:Mutua Universal MUGENAT
    Full Title: Phase III, Single-blinded, placebo-Controlled and randomized Clinical Trial with minimal intervention on the Treatment with Plasma Rich in Growth Factors (PRGF) of Work-site Acute Epicondylitis Res...
    Medical condition: Epicondylitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10014971 Epicondylitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024438-52 Sponsor Protocol Number: 1-2011 Start Date*: 2011-09-05
    Sponsor Name:Fakultní nemocnice v Motole
    Full Title: Impaired sense of smell and its conservative tratment in patients with chronic rhinosinusitis
    Medical condition: The proposed clinical study on impaired sense of smell in patients with chronic rhinosinusitis.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002289-62 Sponsor Protocol Number: ST200-SSMA-14-001 Start Date*: 2014-09-11
    Sponsor Name:SIGMA-TAU, Industrie Farmaceutiche Riunite S.p.A.
    Full Title: Electroneurographic and clinical evaluation in patients with mild / moderate Carpal Tunnel Syndrome , following conservative pharmacological treatment with Nicetile®.
    Medical condition: Carpal Tunnel Syndrome
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005574-38 Sponsor Protocol Number: IJB-SUR-DESIGN-2015 Start Date*: 2016-03-17
    Sponsor Name:Institut Jules Bordet
    Full Title: The DESIGN trial A randomised, Double-blind, placEbo-controlled Study to assess the effectIveness of pectoral nerves block (Pecs) after breast surGery on Piritramide coNsumption.
    Medical condition: Locoregional analgesia in breast surgery (either conservative or non-conservative breast surgery associated with axillary dissection).
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10054799 Perioperative analgesia PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-005039-94 Sponsor Protocol Number: IC2019-05 Start Date*: 2020-12-08
    Sponsor Name:Institut Curie
    Full Title: RETINO 2018 : Ocular conservative treatment for retinoblastoma: efficacy of the new management strategies and visual outcome.
    Medical condition: Retinoblastoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10010331 Congenital, familial and genetic disorders SOC
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-002031-32 Sponsor Protocol Number: PASS-2007 Start Date*: 2008-05-05
    Sponsor Name:AZIENDA OSPEDALIERA S. GERARDO DI MONZA
    Full Title: Phase III study protocol to compare conservative and active treatment during the third stage of labour in physiological childbirth
    Medical condition: THIRD STAGE OF LABOR MANAGEMENT
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004868 10029759 Normal delivery LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004011-30 Sponsor Protocol Number: 987654321 Start Date*: 2005-12-02
    Sponsor Name:Gwent Healthcare NHS Trust
    Full Title: A prospective open study evaluating the use of botulinum toxin in patients with overactive bladder as an alternative to other conservative treatments.
    Medical condition: Overactive bladder syndrome is characterized by a combination of urinary frequency, urgency and urge incontinence.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004665-10 Sponsor Protocol Number: GIADA-CA209-959 Start Date*: 2017-06-27
    Sponsor Name:DIPARTIMENTO SCIENZE CHIRURGICHE, ONCOLOGICHE E GASTROENTEROLOGICHE (DISCOG) - UNIVERSITA' DI PADOVA
    Full Title: THE GIADA TRIAL. ENGAGING THE IMMUNE SYSTEM TO IMPROVE THE EFFICACY OF NEOADJUVANT CHEMO-ENDOCRINE THERAPY FOR PREMENOPAUSAL LUMINAL B BREAST CANCER PATIENTS.
    Medical condition: Hormone-sensitive, HER-negative, Luminal B, premenopausal Breast cancer
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004864 10070577 Oestrogen receptor positive breast cancer LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004117-40 Sponsor Protocol Number: Q03.13.01 Start Date*: 2013-12-19
    Sponsor Name:Fidia Farmaceutici SpA
    Full Title: Randomized, controlled, double-blinded clinical trial, with open-label extension on the efficacy of ultrasound guided injection of hyaluronic acid (500-730 KDa) (HYALGAN®) versus saline solution in...
    Medical condition: Achilles tendinopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003068-47 Sponsor Protocol Number: UROBOTOX 1 Start Date*: 2005-09-22
    Sponsor Name:Region Skåne, Universitetssjukhuset i Lund, Urologiska kliniken
    Full Title: Behandling med botulinumtoxin vid neurogen blåsfunktionsstörning
    Medical condition: The trial addresses patients with severe symptoms of neurogenic detrusor overactivity (urgency and/or urge incontinence). Eligible are those patients who have failed conservative treatment such as ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-005300-19 Sponsor Protocol Number: 2020 Start Date*: 2021-03-01
    Sponsor Name:Medical University Vienna
    Full Title: Intracochlear application versus round window instillation of Triamcinolone acetonide in patients with sudden sensorineural hearing loss-a comparative study
    Medical condition: Sudden sensorineural hearing loss (SSHL)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-018581-23 Sponsor Protocol Number: ECCO Start Date*: 2011-02-17
    Sponsor Name:ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI - FONDAZIONE "G. PASCALE"
    Full Title: CONSERVATIVE MANAGEMENT OF ENDOMETRIAL CANCER AND ATYPICAL HYPERPLASIA
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007063 LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003351-65 Sponsor Protocol Number: RDD110 Start Date*: 2016-03-16
    Sponsor Name:RDD Pharma Ltd.
    Full Title: The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients with Anal Fissure
    Medical condition: Anal Fissure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002586-39 Sponsor Protocol Number: Start Date*: 2006-09-13
    Sponsor Name:Radiological dept. Aalborg Hospital
    Full Title: Placebocontrolled trial, testing the efficacy of Polidocanol injections as a treatment of chronic achilles tendon tendinopatia
    Medical condition: tedinopathy of the achilles tendon
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002650-67 Sponsor Protocol Number: IBERepic/2018 Start Date*: 2018-11-15
    Sponsor Name:Ibermutuamur (Mutua Colaboradora con la Seguridad Social nº 274)
    Full Title: Comparison of the efficacy of autologous platelet rich plasma injections, and extracorporeal shock wave therapy, in the treatment of work –related lateral epicondylitis.
    Medical condition: The epicondylitis is an overuse injury, in most cases, is a self-limited course and responds well to conservative treatment. Its etiology is degenerative and is related to a repetitive overuse and ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-005120-16 Sponsor Protocol Number: 62638 Start Date*: 2018-11-02
    Sponsor Name:Amsterdam UMC, Location VUmc
    Full Title: Ulipristal versus standard surgical treatment in symptomatic uterine fibroids
    Medical condition: Uterine fibroids are very common during reproductive years in women. Minimally invasive treatments are emerging. Myomectomy is the gold standard, preferably laparoscpically, because it removes the ...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10046784 Uterine fibroids LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001680-40 Sponsor Protocol Number: 000015 Start Date*: 2016-05-10
    Sponsor Name:Vestfold Hospital
    Full Title: Pilot study to evaluate the effect of instillation treatment with onabotulinumtoxin A (BOTOX®) in the urinary bladder using Electromotive Drug Application (EMDA) in women with overactive bladder.
    Medical condition: Overactive bladder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003560-74 Sponsor Protocol Number: p2011-1 Start Date*: 2012-09-25
    Sponsor Name:Leiden University Medical Center
    Full Title: Effectiveness of Clonidine for the treatment of radicular pain: A randomized, double-blind and prospective study. (EFFOC study)
    Medical condition: Radicular lumbar pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004318-27 Sponsor Protocol Number: stressfrakturogbisfosfonat Start Date*: 2016-08-31
    Sponsor Name:Oslo University Hospital
    Full Title: Intravenous bisphosphonate in stress fracture treatment -A randomised controlled double blinded multicenter trial
    Medical condition: Stress fractures in the foot
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022520-73 Sponsor Protocol Number: CT/10.15 Start Date*: 2011-07-12
    Sponsor Name:Hellenic Oncology Research Group
    Full Title: Phase II, open-label non-randomized trial to investigate the efficacy of Bevacizumab in combination with dose dense sequential chemotherapy in the neo-adjuvant setting for HER2 negative breast canc...
    Medical condition: Early breast cancer (primary operable HER2-negative breast cancer)
    Disease:
    Population Age: Gender: Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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