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Clinical trials for Cryopreservation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    18 result(s) found for: Cryopreservation. Displaying page 1 of 1.
    EudraCT Number: 2006-003813-42 Sponsor Protocol Number: 107015 Start Date*: 2006-12-21
    Sponsor Name:NV Organon
    Full Title: Follow-up protocol to collect the outcome of frozen-thawed embryo transfer cycles after cryopreservation of embryos in clinical trial 107012
    Medical condition: Controlled Ovarian Stimulation (COS) to induce the development of multiple follicles in patients participating in an Assisted Reproductive Technology (ART) program
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed) AT (Completed) CZ (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2016-000926-21 Sponsor Protocol Number: AMSC-BDT-002 Start Date*: 2016-10-06
    Sponsor Name:Fakultní nemocnice Hradec Králové
    Full Title: Innovation of method cryopreservation for clinical use autologous multipotent mesenchymal stem cells (MSCs) for treatment of extensive skeletal defects in revision surgery of total hip arthroplasty+
    Medical condition: Revision total hip arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10044088 Total hip replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005474-11 Sponsor Protocol Number: Pro.V.En Start Date*: 2015-08-18
    Sponsor Name:USS Centro di Fisiopatologia della Riproduzione, A.O. Papa Giovanni XXIII
    Full Title: Pilot clinical study multicenter, prospective, randomized, open, non-profit to evaluate the efficacy of progesterone administered with different dose subcutaneously compared to progesterone adminis...
    Medical condition: Women undergoing assisted reproduction with autologous cryopreserved embryo transfer.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004872 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004773-28 Sponsor Protocol Number: 38831 Start Date*: 2006-06-30
    Sponsor Name:NV Organon
    Full Title: Follow-up protocol to collect the outcome of frozen-thawed embryo transfer cycles after cryopreservation of embryos in clinical trial 38819
    Medical condition: Controlled Ovarian Stimulation (COS) to induce the development of multiple follicles in patients participating in an Assisted Reproductive Technology (ART) program
    Disease: Version SOC Term Classification Code Term Level
    7.1 10017399 LLT
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed) GB (Completed) SE (Completed) ES (Completed) BE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-000608-16 Sponsor Protocol Number: 5466 Start Date*: 2011-12-21
    Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust [...]
    1. The Newcastle upon Tyne Hospitals NHS Foundation Trust
    2. The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: To evaluate the safety and effectiveness of human ex vivo expanded autologous limbal stem cells for the treatment of unilateral total limbal stem cell deficiency
    Medical condition: unilateral total limbal stem cell deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-005005-12 Sponsor Protocol Number: D2.D12.Bemfola Start Date*: 2018-05-28
    Sponsor Name:UZ Brussel
    Full Title: Initiation of ovarian stimulation with recombinant-human FSH (Bemfola®) in the late follicular phase, a randomised controlled study.
    Medical condition: Subfertility Oocyte donation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042392 Subfertility (female) LLT
    20.0 10042613 - Surgical and medical procedures 10053370 Oocyte donation PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000230-39 Sponsor Protocol Number: FOG 2006 Start Date*: 2008-04-14
    Sponsor Name:Endocrine Society of Czech Republic
    Full Title: Protective effect of gonadoliberin analogues on endocrine and reproduction ovarian function during antitumour treatment in young girls and women in fertile period: Project of pharmacological gonada...
    Medical condition: The patient with diagnosis: Hodgkin disease and leukaemia. Patients starting at adolescence (B3 - B4 for breast development accordig Tanner criteria) till 34 years be included. ...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004458-27 Sponsor Protocol Number: Krypto-3 Start Date*: 2021-01-21
    Sponsor Name:Rigshospitalet
    Full Title: Optimizing the fertility potential of bilateral cryptorchidism by treatment with adjuvant kryptocur.
    Medical condition: Cryptorchidism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10056600 Cryptorchidism LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-005208-20 Sponsor Protocol Number: 2019DEPO-TRIGGER001 Start Date*: 2022-08-10
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Depo-Trigger trial: GnRH agonist DEPOt TRIGGER for final oocyte maturation in breast cancer patients undergoing fertility preservation: a pilot study.
    Medical condition: Female patients with breast cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006279 Breast neoplasm PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004441-32 Sponsor Protocol Number: MSV-crio Start Date*: 2013-03-06
    Sponsor Name:Fundación Teknon
    Full Title: Pilot clinical trial to determine the feasibility and safety of MSV * cryopreserved in the treatment of gonartrosis. * MSV = mesenchymal progenitor cells of expanded autologous bone marrow with GMP...
    Medical condition: Patients diagnosed with gonarthrosis II, III and IV degrees of Kellgren and Lawrence
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003843-30 Sponsor Protocol Number: 26866138MMY2029 Start Date*: 2006-01-05
    Sponsor Name:ORTHO BIOTECH, Division of JANSSEN-CILAG GmbH
    Full Title: Bortezomib and Bendamustine in the Treatment of Refractory/Relapsed Multiple Myeloma
    Medical condition: Cytologically and/or histologically established multiple myeloma requiring treatment, stage II or III (Salmon and Durie). 1. - 3. Relapse or progression with measurable myeloma protein in the bloo...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000808-28 Sponsor Protocol Number: 2015-01 Start Date*: 2016-06-29
    Sponsor Name:Centre Oscar Lambret
    Full Title: Risk of infertility related to adjuvant chemotherapy in young breast cancer patients: Oocyte/embryo cryopreservation
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10006188 Breast cancer female NOS LLT
    Population Age: Adults Gender: Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-014601-13 Sponsor Protocol Number: FPR-09-01 Start Date*: 2010-12-17
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Fertility preservation in patients with breast cancer.
    Medical condition: Fertility preservation in patients with breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006291 HLGT
    9.1 10003539 PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003949-14 Sponsor Protocol Number: 26866138LYM2021 Start Date*: 2008-08-18
    Sponsor Name:ORTHO BIOTECH, Geschäftsbereich der JANSSEN-CILAG GmbH
    Full Title: Pilot study of bortezomib under rituximab standard therapy in patients with relapsed or refractory follicular lymphoma and at least 2 prior therapies
    Medical condition: Patients with histologically proven CD-20-positive follicular lymphoma grade I/II (WHO), stage III/IV (ANN ARBOR) relapsed or refractory to last treatment after at least 2 cytostatic therapies who ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10016904 Follicle centre lymphoma, follicular grade I, II, III NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001989-10 Sponsor Protocol Number: CPI0610-04 Start Date*: 2021-01-08
    Sponsor Name:Constellation Pharmaceuticals, Inc.
    Full Title: A Phase 3, Randomized, Double-blind, Active-Control Study of CPI-0610 and Ruxolitinib vs. Placebo and Ruxolitinib in JAKi Treatment Naive MF Patients
    Medical condition: Myelofibrosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028537 Myelofibrosis PT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10074689 Post polycythemia vera myelofibrosis LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10074690 Post essential thrombocythemia myelofibrosis LLT
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10077161 Primary myelofibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) HU (Completed) DE (Trial now transitioned) AT (Trial now transitioned) PL (Trial now transitioned) CZ (Trial now transitioned) NL (Trial now transitioned) BE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-003572-23 Sponsor Protocol Number: GCP#01.01.030 Start Date*: 2017-12-27
    Sponsor Name:Gamida Cell Ltd
    Full Title: Allogeneic Stem Cell Transplantation of CordIn™, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients with Hemoglobinopathies
    Medical condition: Hemoglobinopathies
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004850 10054658 Thalassemia LLT
    18.0 100000004850 10040645 Sickle cell disease NOS LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-000074-19 Sponsor Protocol Number: GCP#03.01.020 Start Date*: 2014-10-24
    Sponsor Name:Gamida Cell Ltd
    Full Title: Full title of the trial: Allogeneic Stem Cell Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Stem and Progenitor Cells, in Adolescents and Adult Patients with Hematologic...
    Medical condition: High risk haematological malignancies
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10000845 Acute lymphoblastic leukemia LLT
    17.0 100000004864 10025316 Lymphoma NOS LLT
    17.0 100000004864 10000886 Acute myeloid leukemia LLT
    17.0 100000004864 10009015 Chronic myeloid leukemia LLT
    17.0 100000004864 10028534 Myelodysplastic syndrome NOS LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-005159-14 Sponsor Protocol Number: GC P#02.01.001 Start Date*: 2008-04-15
    Sponsor Name:Gamida Cell-Teva Joint Venture Ltd.
    Full Title: A Multi-Center, Multi-National, Historical Cohort Controlled Study to Evaluate Efficacy and Safety of Transplantation of StemEx, Umbilical Cord Blood Stem and Progenitor Cells Expanded Ex Vivo, in ...
    Medical condition: High-risk haematological malignancies (including AML, ALL, CML, NHL, HD, and MDS) with an indication for allogeneic haematopoietic stem cell transplantation, to support haematopoietic reconstitutio...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000886 Acute myeloid leukemia LLT
    9.1 10009015 Chronic myeloid leukemia LLT
    9.1 10001690 ALL LLT
    9.1 10028533 Myelodysplastic syndrome LLT
    9.1 10020206 Hodgkin's disease LLT
    9.1 10029547 Non-Hodgkin's lymphoma LLT
    9.1 10001756 Allogenic bone marrow transplantation therapy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) HU (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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