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Clinical trials for Dopaminergic

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    93 result(s) found for: Dopaminergic. Displaying page 1 of 5.
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    EudraCT Number: 2004-000394-60 Sponsor Protocol Number: ACR16C007 Start Date*: 2004-06-30
    Sponsor Name:A. Carlsson Research AB
    Full Title: A randomised phase II multicentre, double blind, parallel group, placebo controlled study of ACR16 50 mg once daily for the symptomatic treatment of Huntington disease
    Medical condition: ACR16 belongs to a new class of CNS active agents called dopaminergic stabilizers. Dopaminergic stabilizers are compounds that can both enhance and counteract dopamine dependent functions in the CN...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-003286-34 Sponsor Protocol Number: CHUBX2017/22 Start Date*: 2019-03-05
    Sponsor Name:CHU de Bordeaux
    Full Title: In vivo involvement of the cholinergic and dopaminergic systems in the pathophysiology of apathy.
    Medical condition: Apathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10002942 Apathy PT
    20.0 100000004852 10042244 Stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000732-26 Sponsor Protocol Number: ExPD-ESR-18-13512 Start Date*: 2019-10-23
    Sponsor Name:Stockholm Health Care Services
    Full Title: Effect of Exenatide on disease progression in early Parkinson's disease.
    Medical condition: Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001284-12 Sponsor Protocol Number: PA-01 Start Date*: 2014-11-19
    Sponsor Name:University Medical Center Groningen
    Full Title: The Role of the Dopamine D2 Receptor System in Pornographic Addiction – A [11C]-Raclopride PET Study
    Medical condition: pornographic addiction
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000155-12 Sponsor Protocol Number: 2018_49 Start Date*: 2020-05-12
    Sponsor Name:InBrain Pharma SAS
    Full Title: A new concept of continuous dopaminergic stimulation by cerebroventricular administration of A-dopamine (dopamine stored in anaerobia) for severe motor fluctuations in Parkinson’s disease?
    Medical condition: Proof of concept study: prospective, monocentric, controlled randomized study according a cross over design with 2 groups: cerebroventricular administration of A-dopamine versus optimized oral trea...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004583-22 Sponsor Protocol Number: IDRLS Start Date*: 2021-06-13
    Sponsor Name:Medical University of Innsbruck
    Full Title: Prospective analysis of the therapeutic efficacy of iron isomaltoside in combination with or without dopaminergic therapy in patients with restless legs syndrome
    Medical condition: Restless leg syndorme
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005111-16 Sponsor Protocol Number: XP-IIT-0029 Start Date*: 2015-02-16
    Sponsor Name:Instituto de Investigaciones del Sueño
    Full Title: Response to gabapentin enacarbil in two groups of RLS patients: Previously exposed to long-term treatment with dopaminergic agents versus dopaminergic treatment-naive patients.
    Medical condition: RLS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-004825-29 Sponsor Protocol Number: IIS-2011-01 Start Date*: 2011-11-30
    Sponsor Name:Instituto de Investigaciones del Sueño
    Full Title: TREATMENT WITH ROTIGOTINE OF RLS PATIENTS WITH AN INSUFFICIENT RESPONSE TO DOPAMINE AGONIST WITH INTERMEDIATE HALF-LIFE.
    Medical condition: Restless Legs Syndrom
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000891-54 Sponsor Protocol Number: REBOOT-II Start Date*: 2016-11-28
    Sponsor Name:Aging Research Center, Karolinska Institutet and Stockholm University
    Full Title: Effects of enhanced dopaminergic neurotransmission on working memory training efficiency in the healthy elderly - A prospective, single center, randomized, double blind, placebo controlled, paralle...
    Medical condition: No medical condition is under investigation. The project investigates normal age-related decline in intellectual abilities.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006203-36 Sponsor Protocol Number: NL21082.000.08 Start Date*: 2007-05-23
    Sponsor Name:Academic Medical Centre (AMC)
    Full Title: Dopaminergic neurotransmission and cognitive decline in velocardiofacial syndrome
    Medical condition: Dementia in velocardiofacial syndrome
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012267 Dementia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006151-20 Sponsor Protocol Number: D1449L00029 Start Date*: 2006-08-29
    Sponsor Name:University of Erlangen-Nuremberg
    Full Title: Quetiapine and the dopaminergic epigenetic control – a pilot study
    Medical condition: Patients suffering from schizophrenia (ICD10: F20.x) Healthy controls
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039628 Schizophrenia and other psychotic disorders HLGT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002578-36 Sponsor Protocol Number: 2008/0817 Start Date*: 2008-09-10
    Sponsor Name:CHRU de LILLE
    Full Title: Etude d’efficacité et d’acceptabilité d’un traitement cholinergique dans l’apathie parkinsonienne “Cholinergic treatment in Parkinsonian Apathy: ChoPA - I”
    Medical condition: Parkinsonian Apathy without dementia and depression in spite of dopaminergic treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-002342-11 Sponsor Protocol Number: D1449L00033 Start Date*: 2007-04-19
    Sponsor Name:Klinikum Fulda gAG
    Full Title: Multicenter study of neurotransmitters and neuropeptides in schizophrenia: A multidisciplinary study of biological, pharmacokinetic, receptor occupancy and clinical relationships in patients suffer...
    Medical condition: Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001315-71 Sponsor Protocol Number: DPSANARI2012 Start Date*: 2013-10-17
    Sponsor Name:Mercedes Zumarraga Ortiz
    Full Title: Dopaminergic genotype of schizophrenic patients and the benefit of adjunctive aripiprazole to risperidone treatment. The effect on hormonal and metabolic measures
    Medical condition: schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    16.0 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004129-89 Sponsor Protocol Number: Motor-Neuromod_01, Part I-III Start Date*: 2005-09-19
    Sponsor Name:Universitätsklinikum Münster
    Full Title: Potentiation of procedural motor learning by pharmacological neuromodulation and brain stimulation
    Medical condition: Healthy volunteers Patients in the chronic stage (> 1 year) after stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003254-17 Sponsor Protocol Number: IIBSP-SAF-2017-75 Start Date*: 2017-12-21
    Sponsor Name:Institut de Recerca Hospital de la Santa Creu i Sant Pau
    Full Title: A 24-Week, Multicenter, Randomized, Double-blind, Placebo-Controlled, Add-on, Parallel-Group Study to Assess the Effect of Safinamide on Apathy in Patients With Parkinson's Disease
    Medical condition: Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-006302-28 Sponsor Protocol Number: OXYGENE Start Date*: 2012-07-11
    Sponsor Name:UNIVERSITA' DEGLI STUDI DI PARMA
    Full Title: Dopamine modulation of oxytocin prosocial effects
    Medical condition: HEALTHY VOLUNTEERS. FOR PATIENTS WITH AUTISM OR SCHIZOPHRENIA
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005567-26 Sponsor Protocol Number: TVN67 Start Date*: 2007-09-03
    Sponsor Name:University of Aachen
    Full Title: Effects of deep brain stimulation of the nucleus accumbens on the dopaminergic activity in patients with Gilles-de-la-Tourette-syndrome
    Medical condition: The participants under study are recruited from a sample of patients suffering from a severe form of the Gilles-de-la-Tourette-syndrome who are waiting to receive deep-brain stimulation of the ncl....
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001650-29 Sponsor Protocol Number: MF02/11 Start Date*: 2011-12-19
    Sponsor Name:A. Carlsson Research AB
    Full Title: TREATMENT OF MENTAL FATIGUE ("BRAIN FATIGUE") WITH THE DOPAMINERGIC STABILIZER OSU6162 AFTER STROKE AND MILD/MODERATE TRAUMATIC BRAIN INJURY– INCREASE OF PATIENT NUMBER
    Medical condition: Mental fatigue after stroke or mild to moderate head trauma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000434-21 Sponsor Protocol Number: LP1 Start Date*: 2005-06-15
    Sponsor Name:Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
    Full Title: Neurochemische Modulation von Exekutiv- und Gedächtnisfunktionen
    Medical condition: Progressive cognitive decline in physiological aging
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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