Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Dystonia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    80 result(s) found for: Dystonia. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2009-018016-25 Sponsor Protocol Number: MAJKT1 Start Date*: 2010-04-29
    Sponsor Name:Academic Medical Center
    Full Title: Dopamine-serotonin dysbalance in patients with dystonia
    Medical condition: Dystonia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013983 Dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002086-20 Sponsor Protocol Number: A-94-52120-098 Start Date*: 2005-03-09
    Sponsor Name:Ipsen Pharma GmbH
    Full Title: Open, multicentre study on the equivalent efficacy and safety of Botulinum toxin A (500 Units Dysport®) in the treatment of heterogeneous forms of cervical dystonia
    Medical condition: Cervical dystonia (CD), one of the most common forms of focal dystonia, is characterised by an altered head posture, pain in the the neck and shoulder region and hypertrophy of the concerned muscle...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019997-33 Sponsor Protocol Number: 2010/03 Start Date*: 2010-06-02
    Sponsor Name:Leiden University Medical Center
    Full Title: Responsiveness to botulinum toxinum type A in complex regional pain syndrome related fixed dystonia
    Medical condition: CRPS with dystonia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013983 Dystonia LLT
    12.1 10038249 Reflex sympathetic dystrophy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000709-70 Sponsor Protocol Number: Y-47-52120-051 Start Date*: 2005-12-21
    Sponsor Name:Ipsen Ltd
    Full Title: A Phase III Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Dysport® for the Treatment of Cervical Dystonia
    Medical condition: Cervical Dystonia (CD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003410-18 Sponsor Protocol Number: MRZ 60201-0605/1 Start Date*: 2007-09-07
    Sponsor Name:Merz Pharmaceuticals GmbH
    Full Title: Prospective, single-arm, multicenter trial to investigate the efficacy and safety of NT 201 (botulinum neurotoxin type A free of complexing proteins) and the duration of treatment effect after one ...
    Medical condition: Cervical dystonia, predominantly rotational spasmodic torticollis
    Disease: Version SOC Term Classification Code Term Level
    10.0 10064124 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005819-18 Sponsor Protocol Number: DysBot Start Date*: 2009-06-30
    Sponsor Name:Department of Neuroscience, Uppsala University
    Full Title: A comparison of Dysport (100 U/ml) and Botox (100 U/ml) using dose conversion factor 3:1 and 1.7:1 in the treatment of cervical dystonia.
    Medical condition: Cervical dystonia, not multifocal or generalised dystonia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006449-14 Sponsor Protocol Number: MedAff-BTX-0616 Start Date*: 2008-06-20
    Sponsor Name:Allergan Inc.
    Full Title: Multicenter, Double-Blind, Randomized, Controlled, Parallel Comparison of Efficacy and Safety of Fixed Doses of Two Formulations of Botulinum Toxin Type A in the Treatment of Moderate to Severe Ce...
    Medical condition: Moderate to Severe Cervical Dystonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-006169-15 Sponsor Protocol Number: ALLCD001 Start Date*: 2006-05-18
    Sponsor Name:Allergan Limited
    Full Title: A Double-Blind, Randomised, Cross-over, Safety and Efficacy Pilot Study Comparing Two Botulinum Toxin Type-A Products in the Treatment of Moderate to Severe Cervical Dystonia.
    Medical condition: Cervical dystonia is the most common form of focal dystonia prevalent at a rate of 89 per million individuals. Sustained involuntary contractions of the neck muscles, lead to painful and disabling ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004530-16 Sponsor Protocol Number: 191622-090 Start Date*: 2008-02-27
    Sponsor Name:Allergan, Ltd.
    Full Title: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Single Treatment Cycle, Parallel Evaluation of the Safety, Efficacy and Immunogenicity of Two Formulations of BOTOX® (Botulinum Toxin Ty...
    Medical condition: Cervical dystonia: cervical dystonia that have never received treatment with botulinum toxin of any serotype for cervical dystonia or for any other indication
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) HU (Completed) GB (Completed) PT (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001378-13 Sponsor Protocol Number: 001 Start Date*: 2017-02-02
    Sponsor Name:University Hospital Wuerzburg
    Full Title: A randomized, sham-controlled trial of pallidal neurostimulation versus botulinum toxine treatment for cervical dystonia.
    Medical condition: cervical dystonia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000160-28 Sponsor Protocol Number: MusicPlasticity Start Date*: 2020-08-28
    Sponsor Name:Medical University of Vienna
    Full Title: Investigation of SSRI induced neuroplastic changes in musicians using functional magnetic resonance imaging
    Medical condition: Focal dystonia in musicians
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018345-64 Sponsor Protocol Number: 38/10 Start Date*: 2011-03-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Evaluation of the efficacy of Xeomin in the treatment of cervical dystonia (CD) and blepharospasmus (BS) in patients who did not respond to treatment with Botox.
    Medical condition: cervical dystonia, blepharospasmus (BS)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005159 PT
    9.1 10064124 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000446-19 Sponsor Protocol Number: 1720302 Start Date*: 2018-11-30
    Sponsor Name:Revance Therapeutics Inc
    Full Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Trial to Evaluate the Efficacy and Safety of a Single Treatment of DaxibotulinumtoxinA for Injection in Adults ...
    Medical condition: Cervical Dystonia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) PL (Completed) FR (Completed) GB (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019907-43 Sponsor Protocol Number: Y-52-52120-134 Start Date*: 2011-03-04
    Sponsor Name:Ipsen Innovation
    Full Title: A phase III, randomised, double blind and open label phase, active and placebo controlled study comparing the short term efficacy of two formulations of clostridium botulinum type A toxin (Dysport ...
    Medical condition: Cervical Dystonia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) CZ (Completed) DE (Completed) BE (Completed) AT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2022-002192-11 Sponsor Protocol Number: 15-08-2022 Start Date*: 2022-11-24
    Sponsor Name:Pirkanmaan sairaanhoitopiiri
    Full Title: Selän alueen poikkeava aktiivisuus servikaalisessa dystoniassa
    Medical condition: Servikaalinen dystonia, jossa poikkeavaa lihasaktiivisuutta esiintyy kaulan alueen lihaksissa aiheuttaen tyypillisiä virheasentoja kuten pään kiertymistä, kallistumista ja vapinaa. Servikaalista d...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000447-11 Sponsor Protocol Number: 1720304 Start Date*: 2018-11-28
    Sponsor Name:Revance Therapeutics Inc
    Full Title: A Phase 3, Open-Label, Multi-Center Trial to Evaluate the Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults with Isolated Cervical Dystonia (ASPEN-OLS)
    Medical condition: Cervical Dystonia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004859 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) AT (Completed) PL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-005632-32 Sponsor Protocol Number: 2008TOXINA Start Date*: 2009-08-18
    Sponsor Name:Fundació privada de l'Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
    Full Title: INYECCIÓN FRECUENTE DE TOXINA BOTULÍNICA SIN PROTEÍNAS COMPLEJANTES: EVALUACIÓN DEL EFECTO SOBRE EL DOLOR EN DISTONÍA CERVICAL
    Medical condition: Distonía Cervical
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064124 Cervical dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004501-32 Sponsor Protocol Number: NL51240.018.14 Start Date*: 2014-12-11
    Sponsor Name:Academic Medical Center
    Full Title: Infusion VErsus STimulation, a cost-effectiveness analysis of the treatment in advanced Parkinson's disease comparing Continuous Intrajejunal Levodopa Infusion to the traditional standard treetment...
    Medical condition: Patients with advanced PD who's motor symptoms — severe response fluctuations, dyskinesias, painful dystonia and / or bradykinesia — cannot be controlled despite optimal oral pharmacological therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-004985-41 Sponsor Protocol Number: DYSK-PD-2007 Start Date*: 2007-11-29
    Sponsor Name:Department of Neuroscience, neurology
    Full Title: Different dyskinesias in Parkinson's disease and their relation to levodopa pharmacokinetics
    Medical condition: Parkinson's disease, G20.9. Different dyskinesias related to advanced Parkinson's disease will be investigated.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001039-23 Sponsor Protocol Number: Alc 2006 - 01 Start Date*: 2006-04-10
    Sponsor Name:ISTITUTO NEUROLOGICO "CARLO BESTA"
    Full Title: A Pilot Phase II Study for the evaluation of efficacy and tolerability of Gammaidroxybutyrate (ALCOVER) administered by oral route as add on treatmant in patients affected by DYT 11 Myoclonic Dysto...
    Medical condition: DYT 11 Myoclonic Dystonia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 Nervous system disorders SOC
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri May 02 19:18:00 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA