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Clinical trials for Electroporation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    36 result(s) found for: Electroporation. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2021-004987-91 Sponsor Protocol Number: 2020/ABM/01/00098 Start Date*: 2021-11-17
    Sponsor Name:Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu
    Full Title: Effects of calcium electroporation, electrochemotherapy, and irreversible electroporation (IRE-CaCl2, ECT and IRE) on quality of life and progression – free survival in patients with pancreatic can...
    Medical condition: Unresectable pancreatic cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033606 Pancreatic cancer non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002730-36 Sponsor Protocol Number: CaEP68962 Start Date*: 2019-11-14
    Sponsor Name:Department of Dermatology, Bispebjerg Hospital
    Full Title: Calcium electroporation for basal cell carcinomas – a ’Proof of concept’ study
    Medical condition: Basal cell carcinomas
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10042503 Superficial basal cell carcinoma LLT
    21.1 100000004864 10073093 Nodular basal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-009863-75 Sponsor Protocol Number: CEAEP_2009-05-29 Start Date*: 2009-08-26
    Sponsor Name:Karolinska Institutet/ Hospital
    Full Title: El-porCEA: Assessment of safety and immunogenicity of intradermal electroporation of tetwtCEA DNA in patients with colorectal cancer.
    Medical condition: Colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005704-17 Sponsor Protocol Number: AA1232 Start Date*: 2013-03-27
    Sponsor Name:Julie Gehl
    Full Title: Calcium electroporation for the treatment of cutaneous metastases.
    Medical condition: Patients suffering from advanced cancer with cutaneous metastases.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10040892 Skin metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002723-42 Sponsor Protocol Number: HH1222 Start Date*: 2013-09-11
    Sponsor Name:Rigshospitalet
    Full Title: Electrochemotherapy of Head and Neck Cancer
    Medical condition: Head and Neck Cancer. We would like to investigate the possible use of electrochemotherapy in recurrent head and neck cancer. Surgery and radiotherapy, with the possible addition of chemotherapy, c...
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10068476 Electrochemotherapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004315-31 Sponsor Protocol Number: CaEP-B Start Date*: 2020-04-20
    Sponsor Name:Julie Gehl
    Full Title: PHASE II INVESTIGATION OF THE HISTOPATHOLOGIC EFFECT OF CALCIUM ELECTROPORATION ON CANCER IN THE SKIN
    Medical condition: Cutaneous metastases from solid cancer of any histology
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10026693 Malignant skin neoplasm NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004624-41 Sponsor Protocol Number: 24092020 Start Date*: 2021-07-07
    Sponsor Name:Zealand University Hospital
    Full Title: Calcium Electroporation for Malignant GI Bleeding – a randomized controlled trial
    Medical condition: Malignant gastrointestinal bleeding
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10017936 Gastrointestinal bleeding LLT
    12.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10007129 Cancer-related morbidities HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-001128-38 Sponsor Protocol Number: pVAX/rhPSA -EP 2006 Start Date*: 2008-09-30
    Sponsor Name:Uppsala University Hospital
    Full Title: DNA Vaccine Coding for the Rhesus Prostate Specific Antigen (rhPSA) and Electroporation in Patients with Relapsed Prostate Cancer. A Phase I/II Study
    Medical condition: Patients with relapse of prostate cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001023-23 Sponsor Protocol Number: CUTHIVAC002 Start Date*: 2015-08-24
    Sponsor Name:Imperial College London
    Full Title: A Phase I clinical trial to assess the safety and immunogenicity of HIV DNA-C CN54ENV immunisations administered via the Intramuscular and Intradermal methods with and without electroporation follo...
    Medical condition: HIV prophylaxis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005246-59 Sponsor Protocol Number: EO1115 Start Date*: 2016-03-23
    Sponsor Name:Michael Patrick Achiam
    Full Title: Endoscopic electroporation in esophageal cancer
    Medical condition: Esophageal cancer
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004864 10056267 Gastroesophageal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-004314-34 Sponsor Protocol Number: CaEP-R Start Date*: 2019-12-05
    Sponsor Name:Julie Gehl
    Full Title: PHASE II INVESTIGATION OF CALCIUM ELECTROPORATION AS A TREATMENT FOR CUTANEOUS AND SUBCUTANEOUS MALIGNANT TUMOURS
    Medical condition: Cutaneous or subcutaneous malignant tumours
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10026693 Malignant skin neoplasm NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Ongoing)
    Trial results: View results
    EudraCT Number: 2020-000835-33 Sponsor Protocol Number: 300513 Start Date*: 2020-04-15
    Sponsor Name:Zealand University Hospital
    Full Title: Neoadjuvant electrochemotherapy for colorectal cancer – a randomized controlled trial
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-000746-22 Sponsor Protocol Number: 874-2017 Start Date*: 2017-06-22
    Sponsor Name:Department of Dermatology, Zealand University Hospital, Roskilde
    Full Title: Vascular changes in basal cell carcinoma undergoing either electrochemotherapy or photodynamic therapy - assessed with optical coherence tomography
    Medical condition: Basal cell carcinoma in adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2010-022960-10 Sponsor Protocol Number: CVC-202 Start Date*: 2011-03-30
    Sponsor Name:ChronTech Pharma AB
    Full Title: A Phase II Open-Label, Randomized, Parallel group, Safety, Tolerability and Efficacy Study of i.m. Administered CHRONVAC-C in Combination with Electroporation followed by Standard of Care in Chroni...
    Medical condition: Treatment of chronic infections caused by hepatitis C virus genotype 1 strains
    Disease: Version SOC Term Classification Code Term Level
    13.1 10021881 - Infections and infestations 10008912 Chronic hepatitis C LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002901-33 Sponsor Protocol Number: CVC-201 Start Date*: 2007-08-10
    Sponsor Name:Tripep AB
    Full Title: A Phase I/IIa Open-Label, Dose Ranging, Parallel, Safety, Tolerability and Efficacy Study of i.m. Administered ChronVac-C® in Combination with Electroporation in Chronic Hepatitis C Virus Genotype ...
    Medical condition: Treatment of chronic infections caused by hepatitis C virus genotype 1 strains
    Disease: Version SOC Term Classification Code Term Level
    8.1 10008912 Chronic hepatitis C LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004536-22 Sponsor Protocol Number: EPIC2020 Start Date*: 2020-12-08
    Sponsor Name:Ole Thorlacius-Ussing
    Full Title: A phase II Study of Electroporation Potentiated Immunotherapy in Liver Metastatic Pancreatic Cancer
    Medical condition: Metastatic pancreatic cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10033605 Pancreatic cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004623-17 Sponsor Protocol Number: 26092020 Start Date*: 2021-11-09
    Sponsor Name:Zealand University Hospital
    Full Title: Irreversible electroporation in combination with immune checkpoint inhibi-tion , in patients with metastatic pancreatic cancer - A prospective, phase 2 study
    Medical condition: Patients with non-curable pancreatic cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10033575 Pancreas cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002761-63 Sponsor Protocol Number: HPV-301 Start Date*: 2018-04-16
    Sponsor Name:Inovio Pharmaceuticals, Inc.
    Full Title: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 3 STUDY OF VGX-3100 DELIVERED INTRAMUSCULARLY FOLLOWED BY ELECTROPORATION WITH CELLECTRA™ 5PSP FOR THE TREATMENT OF HPV-16 AND/OR H...
    Medical condition: HPV-16 AND/OR HPV-18 RELATED HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESIONS (HSIL) OF THE CERVIX
    Disease: Version SOC Term Classification Code Term Level
    21.1 10022891 - Investigations 10064328 Human papilloma virus test positive PT
    21.1 100000004872 10066237 Cervical high grade squamous intraepithelial lesion LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA) LT (Completed) FI (Completed) DE (Completed) CZ (Prematurely Ended) ES (Completed) PT (Completed) PL (Completed) SK (Completed) BE (Completed) NL (Ongoing) EE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001248-23 Sponsor Protocol Number: 12-CCEE Start Date*: 2014-07-02
    Sponsor Name:All Ireland Cooperative Oncology Research Group
    Full Title: Treatment of Inoperable Colorectal Cancer with Electrochemotherapy through an Endoscopic System
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010039 Colorectal and anal neoplasms malignancy unspecified HLT
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10010023 Colorectal neoplasms malignant HLT
    17.0 100000004856 10010040 Anal and colorectal neoplasms NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-002963-25 Sponsor Protocol Number: EU-HNBE-2003 Start Date*: 2005-03-10
    Sponsor Name:Genetronics, Inc.
    Full Title: An Open-Label Study using the MedPulser Electroporation System To Treat Head and Neck Cancer
    Medical condition: Histologically confirmed primary oral cavity, primary pharyngeal, primary laryngeal, salivary gland, limited recurrent and second primary tumors.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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