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Clinical trials for Emergency department

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    278 result(s) found for: Emergency department. Displaying page 1 of 14.
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    EudraCT Number: 2018-004300-19 Sponsor Protocol Number: 18-PP-04 Start Date*: 2019-03-07
    Sponsor Name:CHU DE NICE
    Full Title: Target-controled infusion with propofol in the Emergency Department : a prospective study on 50 adult patients
    Medical condition: Joint dislocation ; Limb displaced fracture
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10075886 Limb fractures and dislocations HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003220-36 Sponsor Protocol Number: 45112 Start Date*: 2014-05-21
    Sponsor Name:Albert Schweitzer hospital
    Full Title: Remifentanil use for procedural sedation and analgesia in the emergency department
    Medical condition: The research will be conducted in patients that need short painfull treatment in the emergency department and with an indication for PSA. These treatments include: repositioning of fractures, repos...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-005170-11 Sponsor Protocol Number: UCLDexAlf1 Start Date*: 2015-01-26
    Sponsor Name:Cliniques universitaires Saint Luc
    Full Title: Can we get conscious sedation in optimal safety conditions in an emergency department, by combining dexmedetomidine with alfentanil?
    Medical condition: Adult over 18 years, of both sexes, for which a procedural sedation is needed in emergency room.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005442-37 Sponsor Protocol Number: CT200601 Start Date*: 2007-01-08
    Sponsor Name:University Medical Center St Radboud, department of neurology
    Full Title: PITUITARY DAMAGE AFTER TRAUMATIC BRAIN INJURY; Occurrence of growth hormone deficiency at long term follow-up and the beneficial effects of growth hormone substitution on cardiovascular performance...
    Medical condition: isolated growth hormone deficiency after traumatic brain injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002308-15 Sponsor Protocol Number: P160913 Start Date*: 2018-11-09
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: COrticosteroids in acUte uRticAria in emerGency dEpartment
    Medical condition: Adults patients with isolated acute urticaria presenting to the emergency department
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10001106 Acute urticaria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-002137-39 Sponsor Protocol Number: V1 25/07/04 Start Date*: 2004-09-17
    Sponsor Name:
    Full Title: A randomised controlled trial of the combined use of paracetamol and ibuprofen to treat febrile children
    Medical condition: Fevers in childhood not asscoaited with severe disease in the immunocompenetent or fever in the immunocompromised host.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-005116-64 Sponsor Protocol Number: 16092021 Start Date*: 2021-12-13
    Sponsor Name:Aarhus University Hospital, Department of Anesthesiology
    Full Title: Low-dose ketamine as an adjunct to morphine for acute pain in the ED: a randomized, double-blinded, superiority trial
    Medical condition: Acute pain in the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-000503-16 Sponsor Protocol Number: P170903J Start Date*: 2021-02-12
    Sponsor Name:Assistance Publique- Hôpiaux de Paris
    Full Title: Randomized, double-blind, single-centre, randomized study evaluating the efficacy of CLORazepate dipotassium in the treatment of migraine crisis in the emergency department.
    Medical condition: Adults of full age, excluding pregnant or breastfeeding women, admitted to the CUC for headaches
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-000194-31 Sponsor Protocol Number: PenCTU/2010/CTIMP-004 Start Date*: 2011-05-20
    Sponsor Name:Plymouth Hospitals NHS Trust
    Full Title: An open randomised trial of patient controlled analgesia (PCA) versus routine care in the Emergency Department
    Medical condition: Patients presenting to the Emergency Department in severe pain from either musculoskeletal injury or non-traumatic abdominal pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-003773-17 Sponsor Protocol Number: dex_version1 Start Date*: 2017-06-12
    Sponsor Name:Karolinska University Hospital
    Full Title: A prospective randomized open label study Intranasal dexmedetomidine versus inhaled nitrous oxide for children age 3 – 15 years for procedural sedation and analgesia in pediatric emergency departme...
    Medical condition: sedation for emergency procedures
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: View results
    EudraCT Number: 2017-000057-40 Sponsor Protocol Number: dex_vs_ket Start Date*: 2017-06-12
    Sponsor Name:Karolinska University Hospital
    Full Title: A prospective randomized double-blind study Intranasal dexmedetomidine versus intranasal S-ketamine for children age 1 – 3 years for procedural sedation and analgesia in pediatric emergency departm...
    Medical condition: sedation for emergency procedures
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-002498-80 Sponsor Protocol Number: 06062019 Start Date*: 2019-09-24
    Sponsor Name:Mikkel Brabrand
    Full Title: Will titrated oxygen flow to a peripheral oxygen saturation of 88-92% compared with oxygen flow to a saturation >94% reduce mortality in Chronic Obstructive Pulmonary Disease patients with acute ex...
    Medical condition: Acute COPD Exacerbation
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001081-80 Sponsor Protocol Number: NL22172 Start Date*: 2008-06-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort...
    Medical condition: To determine whether a 7-day duration of antibiotic treatment is non inferior to 14-day standard duration of treatment in adults presenting at primary care or emergency department with febrile uri...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-001604-17 Sponsor Protocol Number: APHP220428 Start Date*: 2022-11-15
    Sponsor Name:Assistance Publique - Hôpitaux de Paris
    Full Title: Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers
    Medical condition: Patients With Acute Heart Failure and Elevated Inflammatory Markers in Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005395-40 Sponsor Protocol Number: NSAP-01 Start Date*: 2007-05-03
    Sponsor Name:Barts and The London NHS Trust
    Full Title: Is Buscopan, paracetamol or a combination of both the most effective analgesia for the treatment of non-specific abdominal pain?
    Medical condition: Adult subjects attending the emergency department complaining of acute abdominal pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10000081 Abdominal pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022001-18 Sponsor Protocol Number: RESP_301_2010 Start Date*: 2011-06-30
    Sponsor Name:University College Dublin Clinical Research Centre
    Full Title: A Randomised Trial of Single Dose Oral Dexamethasone versus Multi-Dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in children who attend the Emergency Department
    Medical condition: Exacerbation of asthma in children presenting to the Emergency Department
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003566 Asthmatic attack LLT
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10015575 Exacerbation of asthma LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000348-14 Sponsor Protocol Number: NSTATIN Start Date*: 2014-03-05
    Sponsor Name:Odense University Hospital, Department of Neurology
    Full Title: Statin-treatment and peripheral neuropathy - a randomized clinical trial
    Medical condition: Patients with cerebral infarction or transient ischemic attack.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004469-28 Sponsor Protocol Number: MR311-4501 Start Date*: 2018-03-01
    Sponsor Name:MUNDIPHARMA
    Full Title: Multicentre, randomised, double-blind study assessing the efficacy and safety of Penthrox® combined with a standard analgesia (SoC) in comparison to a placebo combined with a standard analgesia (So...
    Medical condition: Emergency relief of moderate to severe pain associated with trauma in conscious adult patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10044461 Trauma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001601-82 Sponsor Protocol Number: MR311-3506(AMBU-001) Start Date*: 2019-07-08
    Sponsor Name:Mundipharma Pharmaceuticals B.V.
    Full Title: Open randomized clinical trial to compare pain relief between low-dose methoxyflurane and standard of care for the treatment of patients with trauma pain in emergency medical services in the Nether...
    Medical condition: Patients with moderate trauma pain due to extremity injuries for whom the emergency medical services have been called.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001458-14 Sponsor Protocol Number: P130921 Start Date*: 2015-10-01
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10017077 Fracture bone LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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