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Clinical trials for Enabling

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44294   clinical trials with a EudraCT protocol, of which   7351   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    38 result(s) found for: Enabling. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2017-004930-27 Sponsor Protocol Number: MTOR-INHIBITION-SARCOIDOSIS Start Date*: 2019-02-05
    Sponsor Name:Medical University of Vienna
    Full Title: Systems medicine analysis of sarcoidosis by targeting mTOR in a pilot study of sirolimus as treatment in patients with sarcoidosis
    Medical condition: Sarcoidosis with cutaneous affections
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001264-38 Sponsor Protocol Number: MOU-2017-01 Start Date*: 2017-10-16
    Sponsor Name:Masaryk Memorial Cancer Institute
    Full Title: Sequential FDG-PET and Plasma/Tissue miRNA as a Biomarkers of Preoperative Treatment Strategy in Locally Advanced Oesophago-Gastric Cancer
    Medical condition: locally advanced resectable oesophago-gastric adenocarcinoma (Siewert I – III) with T3N0, T4N0, T2 – T4N+, stage Ib – IIIc
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004189-33 Sponsor Protocol Number: REK322442 Start Date*: 2013-11-28
    Sponsor Name:Haukeland University Hospital
    Full Title: ULTRADIAN SUBCUTANEOUS HYDROCORTISONE (USHI) INFUSION IN ADDISON’S DISEASE
    Medical condition: Addison`s disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010625-39 Sponsor Protocol Number: MZ09-PCP-SosPeter Start Date*: 2010-04-21
    Sponsor Name:Prague Psychiatric Center
    Full Title: QEEG cordance and EEG connectivity changes after administration of subanesthetic ketamine doses in depressive disorder patients
    Medical condition: INCLUSION CRITERIA: 1. Men and women at the age between 18 to 65 years, with dextromanual dominance. 2. Patients have to answer DSM IV criteria for the major depressive episode, without psychotic s...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002723-42 Sponsor Protocol Number: HH1222 Start Date*: 2013-09-11
    Sponsor Name:Rigshospitalet
    Full Title: Electrochemotherapy of Head and Neck Cancer
    Medical condition: Head and Neck Cancer. We would like to investigate the possible use of electrochemotherapy in recurrent head and neck cancer. Surgery and radiotherapy, with the possible addition of chemotherapy, c...
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10068476 Electrochemotherapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004601-32 Sponsor Protocol Number: SM4-UG-14 Start Date*: 2015-01-07
    Sponsor Name:Gentofte Hospital
    Full Title: The Effect of Local Anesthetic Volume within the Adductor Canal on Quadriceps Function Evaluated by Electromyography: A Randomized, Observer-Masked, Placebo-Controlled Study in Volunteers.
    Medical condition: Healthy volunteers. Results will be used for optimizing the treatment of post-operative pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    17.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006032-22 Sponsor Protocol Number: 41829447 (ISRCTN No) Start Date*: 2007-04-04
    Sponsor Name:University of Manchester [...]
    1. University of Manchester
    2. Dudley Group of Hospitals NHS Trust
    Full Title: TRial of Atorvastatin for the primary prevention of Cardiovascular Events in Rheumatoid Arthritis
    Medical condition: Rheumatoid arthritis is associated with increased mortality from cardiovascular disease (CVD). Statins have a proven effect in reducing CVD events in at-risk populations, mostly due to their chole...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-004526-24 Sponsor Protocol Number: Panbio/CR/0042006/CT Start Date*: 2008-09-23
    Sponsor Name:Panacea Biotec Ltd
    Full Title: A double-blind, randomized, placebo-controlled, multicentre study to assess the efficacy and safety of Euphorbia Prostrata Dry Extract Tablets in patients of 1° and 2° internal haemorrhoids
    Medical condition: Male and female subjects, at least 18 years of age with a diagnosis of internal haemorrhoids (1° and 2°) confirmed by protoscopic examination and suffering form an uncomplicated and untreated acute...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022577 Internal haemorrhoids LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-004281-18 Sponsor Protocol Number: NC12547 Start Date*: 2020-08-18
    Sponsor Name:Odense University Hospital
    Full Title: Clonidine for Tourniquet-related Pain in Children (CLOTCH) -Study: A Pilot Study
    Medical condition: Pain, which occurs in relation to the use of tourniquets during limb surgery. Tourniquets are positioned on the upper part of the limb in question, inflated and thereby stops perfusion of the limb....
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10053680 Tourniquet application PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003244-27 Sponsor Protocol Number: PANORAMIC-Norway Start Date*: 2023-04-11
    Sponsor Name:Helse Bergen HF
    Full Title: PAxlovid loNg cOvid-19 pRevention triAl with recruitMent In the Community in Norwayy
    Medical condition: COVID-19 SARS-CoV-2
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004848 10084355 COVID-19 virus test positive LLT
    23.1 100000004862 10084401 COVID-19 respiratory infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-000914-38 Sponsor Protocol Number: WINTHER Start Date*: 2013-06-18
    Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR)
    Full Title: A study to select rational therapeutics based on the analysis of matched tumor and normal biopsies in subjects with advanced malignancies
    Medical condition: Advanced malignancies
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004864 10007050 Cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-002602-12 Sponsor Protocol Number: 16/SEP/6613E Start Date*: 2018-01-12
    Sponsor Name:Cardiff and Vale University Health Board
    Full Title: Improving Transplant Opportunities for Patients who are Sensitised (ITOPS) – a feasibility, randomised, controlled phase III trial
    Medical condition: Highly Sensitised Patients(patients with high levels of human leucocyte antigen specific antibodies) awaiting renal transplantation.These patients are difficult to match to a compatible donor and t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2009-013638-26 Sponsor Protocol Number: UCL/08/0359 Start Date*: 2011-08-24
    Sponsor Name:University College London
    Full Title: A phase I/II study of first line Vorinostat with pemetrexed-cisplatin, in patients with malignant pleural mesothelioma
    Medical condition: Malignant pleural mesothelioma
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059518 Pleural mesothelioma malignant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000644-26 Sponsor Protocol Number: 31844 Start Date*: 2018-10-09
    Sponsor Name:University of Southampton
    Full Title: Aspirin To Target Arterial events in Chronic Kidney Disease
    Medical condition: Patients with chronic kidney disease who do not have pre-existing cardiovascular disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2007-005421-30 Sponsor Protocol Number: 07-IN-NX003 Start Date*: 2008-04-17
    Sponsor Name:Nektar Therapeutics
    Full Title: A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Multiple-Dose, Dose Escalation Study to Evaluate the Efficacy, Safety and Tolerability of NKTR-118 in Patients with Opioid-Induced Constipat...
    Medical condition: Opioid induced constipation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003950-24 Sponsor Protocol Number: EOX1.4 Start Date*: 2012-02-14
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: PHASE II TRIAL OF PALLIATIVE EPIRUBICIN, OXALIPLATIN & CAPECITABINE (EOX) CHEMOTHERAPY COMBINED WITH OMEGA-3 FISH OIL INFUSION (OMEGAVEN) IN PATIENTS WITH OESOPHAGO-GASTRIC CARCINOMA
    Medical condition: Unresectable oesophageal and/or gastric cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003425-96 Sponsor Protocol Number: 11091 Start Date*: 2011-12-15
    Sponsor Name:University of Nottingham
    Full Title: Helicobacter eradication to prevent ulcer bleeding in aspirin users: a large simple randomised controlled trial
    Medical condition: Helicobacter eradication to prevent ulcer bleeding in aspirin users
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-001097-24 Sponsor Protocol Number: PHT/2013/01 Start Date*: 2013-05-23
    Sponsor Name:Portsmouth Hospitals NHS trust
    Full Title: Use of N-Acetylcysteine (NAC) and Simeticone as a pre-endoscopic drink to improve mucosal visualisation during gastroscopy: A randomised controlled trial
    Medical condition: Early gastrointestinal lesions in the upper gastrointestinal tract. Our study is not looking at the direct treatment of any particular condition, but the early detecton of lesions. When performin...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10014809 Endoscopy gastrointestinal PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-003102-40 Sponsor Protocol Number: M17CPF Start Date*: 2018-11-01
    Sponsor Name:NKI-AVL
    Full Title: Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertility
    Medical condition: women ≥18 and ≤ 40 years with FIGO stage Ib1 cervical carcinoma with tumor measuring ≥ 2 cm and ≤ 4 cm on physical examination and imaging
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10008230 Cervix neoplasms malignant HLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001171-23 Sponsor Protocol Number: ON/2016/6004 Start Date*: 2017-06-26
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: A multicentre randomised trial of First Line treatment pathways for newly diagnosed Immune Thrombocytopenia: Standard steroid treatment versus combined steroid and mycophenolate.
    Medical condition: Immune Thrombocytopenia
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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