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Clinical trials for Estradiol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    616 result(s) found for: Estradiol. Displaying page 1 of 31.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-003120-37 Sponsor Protocol Number: UFK 2008-002 Start Date*: 2009-05-15
    Sponsor Name:Medizinische Fakultät der Otto von Guericke Universität Magdeburg
    Full Title: EV(E)A Studie Estriol versus Estradiol - Eine prospektive, randomisierte Multizenterstudie zur Evaluation der Wirkung einer lokalen Therapie auf urogenitale Beschwerden, Zytologie und Mammographie...
    Medical condition: vaginal atrophy in postmenopausal women
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015504 Estriol LLT
    9.1 10015499 Estradiol LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003866-19 Sponsor Protocol Number: 83336 Start Date*: 2023-05-01
    Sponsor Name:Amsterdam UMC location AMC
    Full Title: The effect of low-dose rhythmic 17-β-estradiol administration on bone turnover in postmenopausal women
    Medical condition: Osteoporosis prevention
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005258-22 Sponsor Protocol Number: 311926 Start Date*: 2008-02-26
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: A multi-center, double-blind, randomized, parallel-group study to evaluate cycle control and safety of 6 different regimens of an oral contraceptive containing estradiol and drospirenone in healthy...
    Medical condition: The trial will be performed in healthy female volunteers. The intended indication is female contraception.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004544-73 Sponsor Protocol Number: 311623 Start Date*: 2008-01-23
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: A double-blind, randomized, uncontrolled study to evaluate inhibition of ovulation of two oral estradiol / drospirenone regimens in healthy young female volunteers over a period of 3 treatment cycles
    Medical condition: The trial will be performed in healthy female volunteers. The intended indication is female contraception.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001218-39 Sponsor Protocol Number: svenne0405 Start Date*: 2020-11-17
    Sponsor Name:fertility clinic, Herlev university hospital
    Full Title: Estradiol levels in early pregnancy after natural, estradiol + progesterone or gonadotrophin stimulated frozen embryo transfer (FET) cycle
    Medical condition: Infertile women
    Disease: Version SOC Term Classification Code Term Level
    27.1 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001234-34 Sponsor Protocol Number: 118 Start Date*: 2020-04-08
    Sponsor Name:HUS Syöpäkeskus
    Full Title: Effects of Vaginal Estrogens on Serum Estradiol Levels in Postmenopausal Women with Breast Cancer Taking an Aromatase Inhibitor.
    Medical condition: Breast cancer, postmenopausal atrophic vaginitis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004872 10036398 Postmenopausal atrophic vaginitis LLT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    Population Age: Elderly Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000142-22 Sponsor Protocol Number: 148-2016 Start Date*: 2017-05-24
    Sponsor Name:Helm AG
    Full Title: Assessment of therapeutical equivalence of a newly developed vaginal tablet containing 10 μg of estradiol in comparison with a marketed reference product (Vagifem®) – a double-blind, double-dummy, ...
    Medical condition: Investigation of efficacy, safety and tolerability of estradiol vaginal tablets in postmenopausal women with vaginal atrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10047782 Vulvovaginal atrophy LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-004119-30 Sponsor Protocol Number: IP-AVV2019 Start Date*: 2020-01-08
    Sponsor Name:Instituto Palacios
    Full Title: EVALUATION OF THE ACCEPTABILITY AND EFFICACY OF 10 MICROGRAMS OF ESTRADIOL VAGINAL TABLETS VS PROMESTRIENE VAGINAL CREAM
    Medical condition: VULVOVAGINAL ATROPHY
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000689-13 Sponsor Protocol Number: HRT1vs2week.2018 Start Date*: 2018-07-11
    Sponsor Name:University hospital Brussel
    Full Title: Clinical pregnancy rate for frozen embryo transfer with HRT: a pilot study comparing 1 versus 2 weeks of treatment
    Medical condition: Subfertility in need of IVF and IVF-ICSI treatment
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000300-16 Sponsor Protocol Number: P170923J Start Date*: Information not available in EudraCT
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
    Full Title: NA
    Medical condition: NA
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10078075 Gender dysphoria PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-002326-39 Sponsor Protocol Number: 1-10-72-57-15 Start Date*: 2015-08-19
    Sponsor Name:Gynecology Department,Herning Hospital [...]
    1. Gynecology Department,Herning Hospital
    2. Medical Department, Kolding Hospital
    Full Title: The influence of fat intake, estrogen, age, and gender on postprandial lipds and glucose
    Medical condition: Healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004872 10050903 Postmenopausal symptoms LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-000811-24 Sponsor Protocol Number: 308260 Start Date*: 2004-11-19
    Sponsor Name:Schering AG
    Full Title: Multicenter, double-blind, randomized, pleacebo-controlled study to evaluate the oral low-dose estradiol preparations SH T 04170 E (100 µg estradiol) and SH T 04170 F (190 µg estradiol) in postmeno...
    Medical condition: postmenopausal women with high risk for osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10050213 LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-018590-38 Sponsor Protocol Number: 70421 Start Date*: 2010-04-14
    Sponsor Name:LUMC
    Full Title: The thrombogenicity of the dienogest/estradiol valerate containing oral contraceptive (Qlaira)
    Medical condition: We will investigate the thrombogenicity of two different oral contraceptives: dienogest/estradiol valerate (Qlaira) in comparison to levonorgestrel/ethinylestradiol (Microgynon-30) used by healthy ...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030971 Oral contraceptive LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003986-11 Sponsor Protocol Number: 1401-MAD-004-IO Start Date*: 2016-10-22
    Sponsor Name:IVI Madrid
    Full Title: Prospective, double-blinded, randomized clinical trial to evaluate the potential benefitial effect of resveratrol for preventing the ovarian hyperstimulation syndrome.
    Medical condition: Resveratrol may prevent the incidence of ovarian hyperstimulation syndrome by reducing the expression of VEGF and estradiol, improving the haemoconcentration and ascitis Re
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001546-14 Sponsor Protocol Number: 292003 Start Date*: 2006-08-30
    Sponsor Name:NV Organon
    Full Title: A randomized, open-label, comparative trial to evaluate the effects on ovarian function of a monophasic combined oral contraceptive (COC) containing 2.5 mg nomegestrol acetate (NOMAC) and 1.5 mg es...
    Medical condition: Hormonal oral contraception in healthy women
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-002464-24 Sponsor Protocol Number: ESA-13/2010 Start Date*: 2011-07-15
    Sponsor Name:Dr. August Wolff GmbH & Co. KG Arzneimittel
    Full Title: Clinical study to investigate the efficacy and safety of an estradiol containing cream (0.01 % estradiol) in patients with dermatoporosis
    Medical condition: dermatoporosis stage I and II
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004340-32 Sponsor Protocol Number: 308961 Start Date*: 2006-04-20
    Sponsor Name:Bayer Schering Pharma AG
    Full Title: A Multicenter, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, 7 Cycle Duration (196 Days), Phase 3 Study of Oral Estradiol Valerate/Dienogest Tablets for the Treatment of Dysfunction...
    Medical condition: Treatment of prolonged, excessive or frequent bleeding in women without organic pathology who desire oral contraception.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed) SE (Completed) DE (Completed) FI (Completed) HU (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2017-004066-10 Sponsor Protocol Number: MVT-601-3103 Start Date*: 2018-10-19
    Sponsor Name:Myovant Sciences GmbH
    Full Title: SPIRIT EXTENSION: An International Phase 3 Open-Label, Single-Arm, Safety and Efficacy Extension Study to Evaluate Relugolix Co-Administered with Low-Dose Estradiol and Norethindrone Acetate in Wom...
    Medical condition: Endometriosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10014778 Endometriosis PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Ongoing) HU (Completed) BE (Completed) FI (Completed) SE (Completed) PL (Completed) CZ (Completed) BG (Completed) PT (Completed) IT (Completed) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-005304-16 Sponsor Protocol Number: 292001 Start Date*: 2006-06-09
    Sponsor Name:NV Organon
    Full Title: A randomized, open-label, comparative, multi-center trial to evaluate contraceptive efficacy, cycle control, safety and acceptability of a monophasic combined oral contraceptive (COC) containing 2....
    Medical condition: Hormonal oral contraception in healthy women
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Completed) SE (Completed) DK (Completed) FI (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) GB (Completed) IT (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2016-003830-26 Sponsor Protocol Number: LPRI-421/201 Start Date*: 2017-02-24
    Sponsor Name:Exeltis France
    Full Title: Single center, phase II, open label randomized clinical trial to evaluate the inhibition of ovulation of three prolonged release formulations containing a combination of Dienogest and Ethinyl Estra...
    Medical condition: Women’s healthcare (contraception, inhibition of ovulation).
    Disease: Version SOC Term Classification Code Term Level
    19.1 10042613 - Surgical and medical procedures 10010808 Contraception PT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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