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Clinical trials for General surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    717 result(s) found for: General surgery. Displaying page 1 of 36.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2005-001574-27 Sponsor Protocol Number: MR-2005\01 Start Date*: 2005-09-27
    Sponsor Name:AZIENDA OSPEDALIERA DI PERUGIA
    Full Title: Sevoflurane on cardiac surgery: vantage to use during CEC
    Medical condition: general anestetic inalathory also during CEC
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018060 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016094-16 Sponsor Protocol Number: AGO/2009/008 Start Date*: 2010-02-04
    Sponsor Name:University Hospital Ghent
    Full Title: Sevoflurane-Remifentanil interaction: Multiple response surfaces, validation of calibration stimuli, validation of the intraoperative isobole concept and investigating remifentanil induced opioid t...
    Medical condition: American Society of Anesthesia class I and II patients scheduled for surgery under general anesthesia.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10002323 Anesthesia general LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002824-98 Sponsor Protocol Number: ANE_HEPUNOX Start Date*: 2016-10-20
    Sponsor Name:Fundació Hospital Vall Hebron Institut de Recerca
    Full Title: Comparison of three techniques in the management of the postoperatory acute pain, after a general anesthesia based on the control of the nociception.
    Medical condition: Acute postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003515-44 Sponsor Protocol Number: ACA-SPAI-04-22 Start Date*: 2006-12-26
    Sponsor Name:FRANCISCO JAVIER BELDA
    Full Title: Cardioprotective effect of sevoflurane versus propofol used during anesthesia and the postoperative period in patients undergoing coronary bypass surgery. Impact on critical care unit stay. A doubl...
    Medical condition: This study will evaluate the cardioprotective effects of sevoflurane versus propofol during anesthesia and sedation of patients undergoing coronary bypass surgery in terms of maintenance of cardiac...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023942-63 Sponsor Protocol Number: 10-017 Start Date*: 2011-01-17
    Sponsor Name:Clinical Trials Center Aachen, University of Aachen
    Full Title: The safety and feasibility of delivering xenon to patients before and after coronary artery bypass graft implantation: a pilot study Abbreviated study title: A pre- and post-Coronary Artery bypass...
    Medical condition: The aim of this study is to determine whether xenon and remifentanil – as compared to sevoflurane and remifentanil – can be applied safely in patients after CABG implantation for the remaining surg...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005197-11 Sponsor Protocol Number: SENC Start Date*: 2015-04-24
    Sponsor Name:AZIENDA OSPEDALIERA PAPA GIOVANNI XXIII
    Full Title: Sugammadex and neurogical effects central
    Medical condition: patient undergoing elective surgery for which has been indicated only the general anesthesia with tracheal intubation and curarization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004865 10002323 Anesthesia general LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002978-62 Sponsor Protocol Number: 2007/13 Start Date*: 2009-03-18
    Sponsor Name:Hopital Foch
    Full Title: Influence de l’analgésie peropératoire (sufentanil administré selon les critères usuels ou rémifentanil administré par un système automatisé à partir de l’Index Bispectral) sur la consommation de m...
    Medical condition: general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    9.1 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004555-79 Sponsor Protocol Number: 16-115 Start Date*: 2017-08-08
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: Impact of preoperative midazolam on outcome of elderly patients: a multicenter randomised controlled trial
    Medical condition: Under investigation are elderly patients (≥65 years of age) undergoing each kind of surgery with planned general or combined regional and general anaesthesia. Primary, we will investigate the posto...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014346-28 Sponsor Protocol Number: 02273917 Start Date*: 2009-09-28
    Sponsor Name:Erasme hospital
    Full Title: Timing of intubation in a modified rapid sequence induction with remifentanil
    Medical condition: The aim of the trial is to determine the timing for orotracheal intubation using the studied combination of products (Ultiva + Diprivan).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10042609 Surgery LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-001886-33 Sponsor Protocol Number: MK-8616-076-00 Start Date*: 2012-10-30
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: Randomized, Controlled, Parallel Group, Double Blind Trial to Compare the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures Using a 2x2 Fact...
    Medical condition: Patients undergoing elective in-patient laparoscopic cholecystectomy procedures under general anesthesia with neuromuscular relaxation and active reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) FI (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005773-21 Sponsor Protocol Number: IBMS-SPB Start Date*: 2016-05-10
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE
    Full Title: Impact of the serratus plane block in pain and the use of opioids in breast surgery
    Medical condition: Patients undergoing oncological surgery and/or breast reconstruction surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-004163-50 Sponsor Protocol Number: FIBHGM-ECNC002-2013(CETSEVOREM) Start Date*: 2014-04-29
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital
    Full Title: Comparative, randomized, double-blind clinical trial on end-tidal concentration of sevoflurane associated to remifentanil required for insertion of the Supreme Laryngeal Mask vs. Pro-Seal Laryngea...
    Medical condition: Patients requiring general anesthesia in whom the control of the airway is usually done with a supraglottic device.
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10018061 General anesthesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000956-32 Sponsor Protocol Number: 20022012 Start Date*: 2012-06-28
    Sponsor Name:St. Antonius Ziekenhuis
    Full Title: Pharmacokinetics of intravenous acetaminophen and its metabolites in morbidly obese patients
    Medical condition: Morbid obesity
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021022-35 Sponsor Protocol Number: 0908125 Start Date*: 2010-10-12
    Sponsor Name:CHU de Saint-Etienne
    Full Title: Effet of curarization under general anaesthesia on eye movements in non-strabismus children
    Medical condition: Healthy volunteer who will have a surgery requiring curare administration (amygdalectomy...)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10042609 Surgery LLT
    12.1 10057290 Curarization LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004737-37 Sponsor Protocol Number: CORTERAS Start Date*: 2021-11-16
    Sponsor Name:Ziekenhuis Oost-Limburg
    Full Title: The effect of corticosteroids on early recovery after major surgery in elderly patients_ CORTERAS STUDY
    Medical condition: major surgery • off-pump coronary bypass surgery • on-pump coronary bypass surgery • Aortic Valve Replacement Mini Access Surgery • laparoscopic hemicolectomies • thoracoscopic lung resections • fe...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-001139-98 Sponsor Protocol Number: IC2021-07 Start Date*: 2022-06-13
    Sponsor Name:Institut Curie
    Full Title: Opioid-Free versus Opioid-Based Anaesthesia for secondary free-flap reconstruction surgery of the breast: A phase III multicentric randomized controlled study
    Medical condition: Anaesthesia during secondary free flap reconstruction surgery of the breast.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10002323 Anesthesia general LLT
    20.0 10042613 - Surgical and medical procedures 10006305 Breast reconstruction PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-002803-81 Sponsor Protocol Number: TREX Start Date*: 2020-04-03
    Sponsor Name:IRCCS ISTITUTO GIANNINA GASLINI
    Full Title: Neurodevelopmental outcome after standard dose sevoflurane versus low-dose sevoflurane/dexmedetomidine/remifentanil anaesthesia in young children
    Medical condition: Children under the age of 2 years having surgery lasting at least 2 hours
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10018060 General anaesthesia PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001646-10 Sponsor Protocol Number: ANIMAL-523-2014-2569 Start Date*: 2017-06-22
    Sponsor Name:Uppsala University Hospital
    Full Title: Anesthesia Induced Hormonal Oliguria Trial
    Medical condition: Anaesthesia in adult patients undergoing general surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001788-37 Sponsor Protocol Number: HCA-2015-2 Start Date*: 2015-06-29
    Sponsor Name:Heart Center Co. Tampere University Hospital
    Full Title: Effects of volume changes to the plethysmography signal on major surgery patients
    Medical condition: Patients scheduled for elective CABG (Coronary artery bypass surgery). Patients scheduled for elective open major abdominal surgery (gastrointestinal surgery).
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10011090 Coronary artery surgery LLT
    18.0 10042613 - Surgical and medical procedures 10068093 Gastrointestinal surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019591-67 Sponsor Protocol Number: 1008032 Start Date*: 2010-06-01
    Sponsor Name:CHU de SAINT-ETIENNE
    Full Title: Pain assessment during general anesthesia : DOLANS Study
    Medical condition: perioperative analgesia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054799 Perioperative analgesia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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