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Clinical trials for Heart lung machine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    29 result(s) found for: Heart lung machine. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2008-002803-17 Sponsor Protocol Number: 2340 Start Date*: 2008-09-04
    Sponsor Name:Med. Univ. Wien, Klinik Innere Medizin I, Intensivstation
    Full Title: PROPHYLACTIC, DOUBLE BLIND, PLACEBO CONTROLLED RANDOMIZED USE OF HOMEOPATHY FOR PREVENTION OF ATRIAL FIBRILLATION IN PATIENTS WITH AORTOCORONARY BYPASS OR HEART VALVE SURGERY WITH HEART-LUNG MACHINE
    Medical condition: Patients suffering from atrial fibrillation following heart surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001321-17 Sponsor Protocol Number: 11275 Start Date*: 2016-12-02
    Sponsor Name:University of Oxford
    Full Title: A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery
    Medical condition: Low cardiac output states following cardioplegic arrest for cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10007602 Cardiac and vascular procedural complications HLT
    19.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    19.0 10042613 - Surgical and medical procedures 10066123 Cardiopulmonary bypass PT
    19.0 10007541 - Cardiac disorders 10024920 Low output state LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-004198-10 Sponsor Protocol Number: SCT-Cpx-003 Start Date*: 2012-03-22
    Sponsor Name:Swiss Cardio Technologies AG
    Full Title: A Single-Centre, Single Blind, Randomized, Active-Controlled Phase III Non-Inferiority Study to Investigate the Safety and Efficacy of the Cardioplegic Solution Cardioplexol when used during a Ca...
    Medical condition: Medical conditions necessitating an elective surgical coronary artery bypass grafting (CABG) and/or a valve repair/replacement.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003589-25 Sponsor Protocol Number: Levo-AKI Start Date*: 2014-11-11
    Sponsor Name:Sahlgrenska Universitetssjukhuset/Sahlgrenska
    Full Title: The effect of levosimendan, on renal blood flow, function and oxygen uptake during acute renal failure after cardiac surgery
    Medical condition: Acute kidney injury postoperatively in connection with heart surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016954-42 Sponsor Protocol Number: SCT-Cpx-001 Start Date*: 2010-10-28
    Sponsor Name:Swiss Cardio Technologies AG
    Full Title: Randomized Clinical Safety and Efficacy Investigation of the Swiss Cardio Technologies Cardioplexol Solution in comparison with Buckberg Solution
    Medical condition: Medical conditions necessitating an elective surgical coronary artery bypass grafting (CABG) and/or a valve repair/replacement.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2021-001456-34 Sponsor Protocol Number: ArgatrobanECMO_1.2 Start Date*: 2021-07-08
    Sponsor Name:Medical University of Vienna
    Full Title: A prospective randomized pilot trial on safety and feasibility of Argatroban as anticoagulant in patients with extracorporeal membrane oxygenation (ECMO)
    Medical condition: patients requiring treatment with extracorporeal membrane oxygenation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2022-002259-20 Sponsor Protocol Number: CASUAL_ECMO Start Date*: 2023-08-17
    Sponsor Name:Medical University of Vienna
    Full Title: A three-arm randomized controlled non-inferiority pilot study Comparing Anticoagulation Strategies using Unfractionated heparin, Argatroban and Low-molecular-weight heparin for Extracorporeal Memb...
    Medical condition: patients with indication for extracorporeal membrane oxygenation therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-002311-10 Sponsor Protocol Number: SCT-Cpx-004 Start Date*: 2018-10-09
    Sponsor Name:Swiss Cardio Technologies AG
    Full Title: A multi-center, open label, single group, observational study to investigate the effects of training on the administration of Cardioplexol (TM)
    Medical condition: Medical conditions with the need for an elective surgical coronary artery bypass grafting (CABG) and/or a valve repair/replacement .
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002647-27 Sponsor Protocol Number: 092004 Start Date*: 2005-03-10
    Sponsor Name:Universitätsklinik für Kinder-und Jugendheilkunde
    Full Title: FSME (human tick-borne encephalitis) - vaccination in children after thymectomy
    Medical condition: In children who undergo open heart surgery because of heart vitium, for surgical reasons the thymus has to be removed. If thymectomy in early childhood alters the function of the immunsystem has be...
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004684-12 Sponsor Protocol Number: iNO_Protocol_V1.1_16.07.17 Start Date*: 2019-05-16
    Sponsor Name:Lady Cilento Children's Hospital
    Full Title: Nitric Oxide during Cardio Pulmonary Bypass during surgery for congenital heart defects: A Randomised Controlled Trial.
    Medical condition: Congenital heart disease ranks still within the top causes of infant mortality in industrialized countries. Despite considerable advances over the past decade, the exposure to cardiopulmonary bypas...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023093-39 Sponsor Protocol Number: SIRS Start Date*: 2011-09-08
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: Steroids In caRdiac Surgery Trial
    Medical condition: Require CPB for any cardiac surgical procedure
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) CZ (Completed) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015779-28 Sponsor Protocol Number: Start Date*: 2009-12-11
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: A single-centre randomised controlled trial of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients having isolated coronary artery bypass grafting (CABG) or ao...
    Medical condition: Myocardial injury after CABG or AVR surgery using cardiopulmonary bypass
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002663-33 Sponsor Protocol Number: NUH-ALS-2015-04 Start Date*: 2018-11-05
    Sponsor Name:Alloksys Life Sciences BV
    Full Title: Preventing Oxidative stress induced Ischemic Injury and Systemic Inflammation complications during and after invasive Cardiac surgery with Alkaline Phosphatase (APPIRED III)
    Medical condition: systemic inflammation as side-effect of heart-lung machine during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned) NL (Completed) AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002090-12 Sponsor Protocol Number: Ilocard Start Date*: 2009-03-04
    Sponsor Name:Hospital of the university of munich
    Full Title: Effect of Iloprost inhalation before and during extracorporeal circulation (ECC) on perioperative morbidity and outcome in high risk cardiac surgical patients
    Medical condition: In this study effects of the intra operative, prophylactic inhalation of Iloprost (Ventavis) before and during extracorporal circulation on perioperative morbidity and outcome in high risk cardiac ...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10036727 Primary pulmonary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-002385-39 Sponsor Protocol Number: HSPOD Start Date*: 2018-12-06
    Sponsor Name:County Council of Västerbotten
    Full Title: Infusion of hypertonic solutions: A risk factor for delirium after cardiac surgery? A randomised double blinded controlled trial.
    Medical condition: The present investigation aims to investigate the risk of developing delirium after cardiac surgery, when using a hyperosmolar priming solution for cardiopulmonary bypass
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001086-32 Sponsor Protocol Number: 19-001_AMG Start Date*: 2020-01-02
    Sponsor Name:RWTH Aachen University represented by the Rector himself, represented by the Dean of the Medical Faculty
    Full Title: ADVANCE-CSX Pilot – Antioxidant Treatment with Vitamin C in Cardiac Surgery Patients – a Clinical Pilot Study
    Medical condition: Patients undergoing high-risk open-heart surgery with the use of cardiopulmonary bypass (CPB)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-004082-41 Sponsor Protocol Number: DELIcu Start Date*: 2013-03-06
    Sponsor Name:Dekan of Faculty of Medicine of Goethe-University Frankfurt
    Full Title: Monocenter, double blind, randomised, placebo controlled study t evaluate Physostigmin for the Treatment of delirium in perioperative intensive care medicine
    Medical condition: patients with delirium in perioperative intensive care medicine
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10012221 Deliria (incl confusion) HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-002756-21 Sponsor Protocol Number: 1663/2020 Start Date*: 2021-02-23
    Sponsor Name:Department of Cardiothoracic Anesthesia and Intensive Care Medicine, Medical University of Vienna
    Full Title: Plasma Pharmacokinetics of Prophylactic Cefazolin Administered for Cardiac Surgery: Comparison of Cardiopulmonary Bypass Priming with Additive Human Albumin 20% vs.Pure Crystalloid Priming: A singl...
    Medical condition: This is a pharmacokinetic trial for patients undergoing cardiac surgery. It will be investigated whether cardiopulmonary bypass priming substituted with human albumin 20% has an effect on the pharm...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004936-75 Sponsor Protocol Number: EVOLUTION Start Date*: 2012-05-29
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: An Evaluation of Losmapimod in patients with Chronic Obstructive Pulmonary Disease (COPD) with systemic inflammation stratified using fibrinogen (EVOLUTION)
    Medical condition: The trial team will be looking at patients with Chronic Obstructive Pulmonary Disease and how inflammation affects them.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-002992-27 Sponsor Protocol Number: 201496 Start Date*: 2014-10-10
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: 201496: A Study to Evaluate the Efficacy and Safety of 15mg BID Losmapimod (GW856553) Compared to Placebo in Frequently Exacerbating Subjects with Chronic Obstructive Pulmonary Disease (COPD).
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    17.0 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended) DE (Completed) BG (Completed) ES (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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