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Clinical trials for Hydrocortisone

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    151 result(s) found for: Hydrocortisone. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2012-001104-37 Sponsor Protocol Number: ME/2011/3709 Start Date*: 2014-10-06
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: Pulsed glucocorticoid replacement therapy for patients with adrenocortical insufficiency secondary to Addison’s disease and congenital adrenal hyperplasia
    Medical condition: Addison's disease and Congenital Adrenal Hyperplasia
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004848 10011195 Cortisol LLT
    17.0 100000004848 10020518 Hydrocortisone LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-000864-82 Sponsor Protocol Number: hydrocortisone Start Date*: 2011-12-22
    Sponsor Name:University Medical Center Groningen
    Full Title: A randomized double blind cross-over study of the effects of low dose and high dose hydrocortisone replacement therapy on cognition, quality of life, metabolic profile and somatosensation in patien...
    Medical condition: Secondary adrenal insufficiency
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022891 - Investigations 10020518 Hydrocortisone LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-004286-18 Sponsor Protocol Number: HPA-PTSD-1 Start Date*: 2008-08-05
    Sponsor Name:Central Institute of Mental Health
    Full Title: Monocentric, Double-blind Placebo-Controlled, Randomized Cross-Sectional Clinical Trial of Hydrocortisone (10 and 30mg/d) in Outpatients with Posttraumatic-Stress- Disorder (PTSD) ...
    Medical condition: Intrusions in patients with posttraumatic stress disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001090-40 Sponsor Protocol Number: ATC017HC Start Date*: 2015-06-22
    Sponsor Name:The London Clinic
    Full Title: An open label pilot study to investigate the effects of two preparations of hydrocortisone (Hydrocortisone 100mg/ml and Solu-Cortef) injected intramuscularly into the deltoid and upper thigh muscle...
    Medical condition: Addison's Disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 10014698 - Endocrine disorders 10001130 Addison's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-010963-18 Sponsor Protocol Number: LEO80190-O25 Start Date*: 2009-09-29
    Sponsor Name:LEO Pharmaceutical Products Ltd. A/S (LEO Pharma A/S)
    Full Title: A phase 3 study comparing an ointment containing calcipotriol 25 mcg/g plus hydrocortisone 10 mg/g (LEO 80190 ointment) with hydrocortisone 10 mg/g ointment, both applied once daily in the treatmen...
    Medical condition: Psoriasis vulgaris on the face and on the intertriginous areas.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-004782-18 Sponsor Protocol Number: LEO 80190-O21 Start Date*: 2008-06-03
    Sponsor Name:LEO Pharmaceutical Products Ltd. A/S (LEO Pharma A/S)
    Full Title: Calcipotriol Plus Hydrocortisone in Psoriasis Vulgaris on the Face and on the Intertriginous Areas. A phase 3 study comparing an ointment containing calcipotriol 25 mcg/g plus hydrocortisone 10 mg/...
    Medical condition: Psoriasis vulgaris on the face and on the intertriginous areas The face is defined as: forehead including hairline, cheeks, nose, chin and ears (excluding the auditory meatus). In case of baldness...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) LV (Completed) CZ (Completed) SI (Completed) NL (Completed) BE (Completed) FR (Completed) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002203-40 Sponsor Protocol Number: 07.0056 Start Date*: 2007-10-03
    Sponsor Name:St. George's, University of London
    Full Title: Effect of hydrocortisone on desire to smoke and tobacco withdrawal symptoms
    Medical condition: Nicotine addiction; specifically, cortisol deficiency following smoking cessation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-002039-32 Sponsor Protocol Number: PlenadrEMA/1.1/2014 Start Date*: 2014-09-02
    Sponsor Name:Rigshospitalet, Copenhagen University Hospital
    Full Title: PlenadrEMA study - Effect of modified-release compared to conventional hydrocortisone on fatigue, measured by Ecological Momentary Assessments; a pilot study to assess feasibility, responsiveness o...
    Medical condition: Secondary adrenal insufficiency due to hypopituitarism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10052382 Secondary adrenal insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-001069-20 Sponsor Protocol Number: HIDROGUM21 Start Date*: 2022-01-12
    Sponsor Name:Vall d'Hebron Hospital Universitari
    Full Title: Tolerability and acceptance of two oral hydrocortisone compounding formulation for pediatrics
    Medical condition: Adrenal hyperplasia or isolated primary adrenal insufficiency or panhypopituitarism (secondary or tertiary adrenal insufficiency)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004802-24 Sponsor Protocol Number: NL68556.091.18 Start Date*: 2019-05-20
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Optimizing timing of glucocorticoid treatment in children with congenital adrenal hyperplasia
    Medical condition: Congenital adrenal hyperplasia (CAH) is a disorder of adrenal steroid synthesis leading to cortisol deficiency and an increase in androgen production.Treatment in children consists of hydrocortis...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2014-002265-30 Sponsor Protocol Number: Infacort003 Start Date*: 2015-02-19
    Sponsor Name:Diurnal Limited
    Full Title: A Phase 3 open-label study of Infacort® in neonates, infants and children less than 6 years of age with adrenal insufficiency.
    Medical condition: Adrenal Insufficiency (AI) in children is most commonly due to Congenital Adrenal Hyperplasia (CAH) and results in cortisol deficiency with or without aldosterone deficiency and androgen excess. Cu...
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-003835-30 Sponsor Protocol Number: Start Date*: 2005-05-26
    Sponsor Name:Belfast City Hospital
    Full Title: An open label, single centre, assessor blind pilot study comparing topical tacrolimus 0.1% and hydrocortisone ointment 1% in the treatment of flexural psoriasis
    Medical condition: flexural psoriasis
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-003668-29 Sponsor Protocol Number: DIUR-014 Start Date*: 2022-02-04
    Sponsor Name:Diurnal Limited
    Full Title: A Randomized, Double-Blind, Active-Controlled, Phase 3 Study of Chronocort Compared with Immediate-Release Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over with Congenital ...
    Medical condition: Congenital Adrenal Hyperplasia due to 21-hydroxylase deficiency
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-014909-14 Sponsor Protocol Number: CS/München01 Start Date*: Information not available in EudraCT
    Sponsor Name:Max-Planck-Institut für Psychiatrie
    Full Title: Neuropsychological effects of hydrocortisone substitution in patients with partial adrenal insufficiency after traumatic brain injury or subarachnoidal haemorrhage
    Medical condition: hormonal deficiency after traumatic-brain- injury (TBI) or subarachnoidal haemorrhage (SAH)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10011198 Cortisol decreased LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-007603-32 Sponsor Protocol Number: 0726 Start Date*: 2008-07-24
    Sponsor Name:CHU de Grenoble
    Full Title: Opothérapie par hydrocortisone après injection unique d'etomidate chez le patient de réanimation
    Medical condition: patients admis en réanimation ayant reçu une injection unique d'etomidate dans le cadre d'une induction en séquence rapide en situation préhospitalière ou au déchocage.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000458-40 Sponsor Protocol Number: Infacort004 Start Date*: 2015-10-20
    Sponsor Name:Diurnal Limited
    Full Title: Open-label, long-term follow-up of safety and biochemical disease control of Infacort® in neonates, infants and children with congenital adrenal hyperplasia and adrenal insufficiency previously enr...
    Medical condition: Adrenal Insufficiency (AI) in children is most commonly due to Congenital Adrenal Hyperplasia (CAH) and results in cortisol deficiency with or without aldosterone deficiency and androgen excess. ...
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003705-17 Sponsor Protocol Number: LUMC-NECH-201801-ACA Start Date*: 2019-03-22
    Sponsor Name:LUMC
    Full Title: Prevention of neuropsychiatric adverse effects caused by dexamethasone: translational insights from a placebo-controlled trial with hydrocortisone.
    Medical condition: Neuropsychiatric adverse effects which can be caused by dexamethasone. For example delirium, anxiety, depression, mania and psychosis. But also cognitive impairment and sleep disturbance.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-000212-16 Sponsor Protocol Number: HYKS-190116 Start Date*: 2016-04-12
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Hydrocortisone vs. pasireotide in preventing pancreatic fistula and other complications after pancreatic resection - a prospective, randomized, controlled trial
    Medical condition: Patients undergoing pancreatic resection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2017-002738-22 Sponsor Protocol Number: 62388 Start Date*: 2018-03-02
    Sponsor Name:Princess Máxima Center of Pediatric Oncology
    Full Title: Double blind placebo controlled randomized intervention study to validate the beneficial effect of hydrocortisone on dexamethasone-induced neurobehavioral side effects in pediatric acute lymphoblas...
    Medical condition: Acute lymphoblastic leukemia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10024338 Leukemia lymphoblastic acute LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-001768-30 Sponsor Protocol Number: HYSS 3 Start Date*: 2006-01-04
    Sponsor Name:EM-kliniken
    Full Title: Comparison of 2 and 4 doses hydrocortison substitution with regard to plasma concentration and quality of life.
    Medical condition: We aim to study patients with cortisol deficiency caused by primary adrenal insufficiency (Addison’s disease of autoimmune origin).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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