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Clinical trials for Inhibition

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,563 result(s) found for: Inhibition. Displaying page 1 of 79.
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    EudraCT Number: 2017-005068-16 Sponsor Protocol Number: 221181 Start Date*: 2018-02-14
    Sponsor Name:University Hospital of Aarhus
    Full Title: Measurement of Acetylsalicylic acid Concentration and Effect - MACE
    Medical condition: Healthy volunteers (Prophylaxis of arterial thrombosis)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002060-34 Sponsor Protocol Number: V1.0 Start Date*: 2008-11-20
    Sponsor Name:Medizinische Universität Wien; Univ.Klin.f.Innere Med. III, Abt.f.Gastroenterologie u. Hepatologie
    Full Title: Impact of Inhibition of Thrombocyte Activation on the course of chronic Hepatitis C
    Medical condition: Chronic Hepatitis C
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-002896-32 Sponsor Protocol Number: D5136C00001 Start Date*: 2013-01-16
    Sponsor Name:AstraZeneca AB
    Full Title: A multicenter, double-blind, placebo-controlled, pharmacokinetic, pharmacodynamic, safety and tolerability study in patients aged 12 to <18 years of age with a central venous catheter to support pr...
    Medical condition: Thrombosis, thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    14.1 10005329 - Blood and lymphatic system disorders 10050661 Platelet aggregation inhibition PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002081-19 Sponsor Protocol Number: 252313 Start Date*: 2006-10-16
    Sponsor Name:VU University Medical Centre
    Full Title: The Effects of EGFR Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis A phase II open-label safety and efficacy study.
    Medical condition: Pulmonary arterial hypertension associated with systemic sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001841-14 Sponsor Protocol Number: PICOLO Start Date*: 2005-01-10
    Sponsor Name:SANOFI-SYNTHELABO
    Full Title: Dose-ranging pharmacodynamic assessment of platelet aggregation inhibition with clopidogrel in children of Blalock-Taussig shunt age categories (neonates and infants/toddlers)
    Medical condition: neonates or infants/toddlers at risk of thrombosis
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed) BE (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-004655-20 Sponsor Protocol Number: LIGHT Start Date*: 2019-05-30
    Sponsor Name:HELLENIC INSTITUTE FOR THE STUDY OF SEPSIS
    Full Title: CLINICAL EFFICACY OF INHIBITION OF ORGAN DYSFUNCTION THROUGH BERMEKIMAB IN SYSTEMIC SCLEROSIS: A PROOF-OF-CONCEPT DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL (THE LIGHT TRIAL)
    Medical condition: CLINICAL EFFICACY OF INHIBITION OF ORGAN DYSFUNCTION THROUGH BERMEKIMAB IN SYSTEMIC SCLEROSIS: A PROOF-OF-CONCEPT DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL (THE LIGHT TRIAL)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10078638 Systemic scleroderma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018435-18 Sponsor Protocol Number: P01432 Start Date*: 2010-05-21
    Sponsor Name:Papworth Hospital NHS Foundation Trust
    Full Title: Assessing Platelet Inhibitory Response to Clopidogrel – Feasibility, Safety and Cost Analysis of a Tailored Platelet Inhibition Strategy for Elective PCI Patients
    Medical condition: To investigate the feasibility, safety and cost of using the platelet assay VerifyNow-P2Y12 to guide optimal P2Y12 platelet inhibition in patients undergoing elective PCI, compared with standard tr...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-002233-19 Sponsor Protocol Number: ASA-CABG-01 Start Date*: 2011-10-14
    Sponsor Name:Karolinska Institute
    Full Title: Antiplatelet effects of once versus twice daily dosing of aspirin after coronary artery bypass grafting
    Medical condition: Patients having successfully undergone coronary artery bypass graft (CABG) surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001285-15 Sponsor Protocol Number: KOIIM-2019-1 Start Date*: 2019-06-28
    Sponsor Name:University Medical Centre Ljubljana
    Full Title: Platelet inhibition with cangrelor in comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Medical condition: Comatose survivors of out-of-hospital cardiac arrest undergoing primary percutaneous coronary intervention
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000115-32 Sponsor Protocol Number: EVE112-CT02-2015 Start Date*: 2016-02-25
    Sponsor Name:Evestra GmbH
    Full Title: Characterization of ovulation inhibition of a new vaginal delivery system (EVE 112, Evestra/Germany) containing etonogestrel and ethinylestradiol – an open label, single centre, comparative, parall...
    Medical condition: Investigation of ovulation inhibition for indication of contraception.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10073728 Hormonal contraception LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012815-16 Sponsor Protocol Number: ROSANNA Start Date*: 2010-03-18
    Sponsor Name:Technische Universität München
    Full Title: Dosis-Wirkungsstudie von Rocuronium unter Propofol-Anästhesie (Rocuronium Dose Finding Study after single shot or steady state propofol anesthesia)
    Medical condition: Rocuronium dose finding study; evaluation of effective doses (ED 50 and ED 95) of rocuronium after single shot or steady state propofol anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029315 Neuromuscular blockade LLT
    9.1 10029315 Neuromuscular blockade PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-004664-36 Sponsor Protocol Number: EVE116-CT03-2017 Start Date*: 2018-06-19
    Sponsor Name:Evestra GmbH
    Full Title: Characterization of ovulation inhibition of a new vaginal delivery system containing trimegestone - an open-label, single-centre study in healthy females of childbearing potential
    Medical condition: Investigation of ovulation inhibition for indication of contraception
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023861-23 Sponsor Protocol Number: EPU P61 Start Date*: 2011-01-31
    Sponsor Name:Maastricht University
    Full Title: The effect of P-glycoprotein transport inhibition on brainmechanisms of sedation and cognitive impairment following antihistamines in healthy volunteers
    Medical condition: To assess the effects of inhibition of the P-glycoproteine transporter (by verapamil 120 mg) on cetirizine 15 mg in healthy volunteers.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007276-41 Sponsor Protocol Number: Ram_GEP_1 Start Date*: 2008-05-13
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: Gene expression profiling in skeletal muscle of healthy subjects treated with ramipril
    Medical condition: healthy young males
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003186-40 Sponsor Protocol Number: DM-ASA 001 Start Date*: 2007-09-05
    Sponsor Name:Karolinska Institute
    Full Title: Evaluation of antiplatelet effects of different dosages of aspirin in type 2 diabetic patients.
    Medical condition: Patients with type 2 diabetes mellitus with an indication for aspirin treatment or already on aspirin treatment.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004794-41 Sponsor Protocol Number: Vista Start Date*: 2017-03-02
    Sponsor Name:Academical medical centre, dep of internal medicine
    Full Title: Arterial wall inflammation measured with 18F-FDG PET/CT in patients with statin intolerance before and after treatment with a PCSK-9 inhibitor
    Medical condition: Patients with CV-risk and statin intolerance due to statin-associated muscle symptoms (SAMS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004844-59 Sponsor Protocol Number: CAEB071A2117 Start Date*: 2008-01-31
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A two part, randomized, placebo controlled study to evaluate the pharmacokinetics and cardiovascular pharmacodynamics of AEB071 in combination with ritonavir in healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2020-001655-41 Sponsor Protocol Number: 35RC19_8877_DIPLOID Start Date*: 2020-09-15
    Sponsor Name:CHU de Rennes
    Full Title: P-glypoprotein inhibition effect on the pharmacokinetics of two tacrolimus formulations: prolonged and extended-release
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002941-49 Sponsor Protocol Number: ERRITI Start Date*: 2017-01-31
    Sponsor Name:University Hospital Essen (Anstalt des öffentlichen Rechts)
    Full Title: Enhancing Radioiodine Incorporation into Radio Iodine Refractory Thyroid Cancers with MAPK Inhibition: A single center pilot study
    Medical condition: Radio Iodine Refractory Thyroid Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000395-32 Sponsor Protocol Number: 2006001 Start Date*: 2006-03-29
    Sponsor Name:King's College London
    Full Title: The effect of COX-2 Inhibition on Reducing Central Sensitisation of Pain in Osteoarthritis
    Medical condition: Osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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