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Clinical trials for Kidneys

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    178 result(s) found for: Kidneys. Displaying page 1 of 9.
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    EudraCT Number: 2015-002585-23 Sponsor Protocol Number: ANJ-02-2015 Start Date*: 2016-01-08
    Sponsor Name:Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro)
    Full Title: The effect of 3% NaCl and furosemid on biomarkers and the kidneys managment of sodium and water, vasoactive hormones and GFR in healthy subjects.
    Medical condition: Healthy volunteers (The effect of flurosemide, together with an infusion of hypertone saline, on the kidneys, using biomarkers)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001265-41 Sponsor Protocol Number: 200621 Start Date*: 2006-06-16
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Trust
    Full Title: A comparison of Sirolimus versus Tacrolimus as a delayed treatment of recipients of non heart beating donor kidneys after anti-IL2 monoclonal antibody
    Medical condition: Kidney transplantation from non heart beating donors for end-stage renal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001946-26 Sponsor Protocol Number: AMITNED Start Date*: 2016-01-19
    Sponsor Name:Aarhus University Hospital
    Full Title: Amilorid treatment of nephrotic edema
    Medical condition: Childhood idiopathic nephrotic syndrome (NS)
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-000226-38 Sponsor Protocol Number: 156-13-210 Start Date*: 2015-01-08
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc.
    Full Title: A Phase 3b, Multi-center, Randomized-withdrawal, Placebo-controlled, Double-blind, Parallel-group Trial to Compare the Efficacy and Safety of Tolvaptan (45 to 120 mg/day, Split-dose) in Subjects ...
    Medical condition: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004850 10036046 Polycystic kidney, autosomal dominant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed) SE (Completed) HU (Completed) DK (Completed) NL (Completed) BE (Completed) ES (Completed) CZ (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-005008-88 Sponsor Protocol Number: SL-2-2017 Start Date*: 2018-05-09
    Sponsor Name:Medicinsk Forskning, Regionshospitalet Holstebro, Hospitalsenheden Vest
    Full Title: Test of reliability of PET-rubidium82-scan in determination of renal blood flow in healthy subjects
    Medical condition: We wish to test the reliability of PET-rubium-82-scans in regards to determination of renal blood flow
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-000637-35 Sponsor Protocol Number: Glory 2 Start Date*: 2006-07-07
    Sponsor Name:Addenbrookes Hospital Cambridge University Hospitals NHS Foundation Trust
    Full Title: double blind crossover compariosn of diuretics in young patients with low-renin hypertension
    Medical condition: Low-renin hypertension
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001219-26 Sponsor Protocol Number: N20PIP Start Date*: 2021-02-11
    Sponsor Name:tichting Het Nederlands Kanker Instituut_Antoni van Leeuwenhoek
    Full Title: Prostatic Artery Injection vs Intra-Venous Injection of 18F-DCFPyL to evaluate treatment strategy in Prostate Cancer
    Medical condition: Prostate cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005796-14 Sponsor Protocol Number: 1/2013 Start Date*: 2014-05-13
    Sponsor Name:Medizinische Universität Wien
    Full Title: A randomized, pilot study to assess the impact of single nucleotide polymorphisms in the ABCB1 and ABCG2 genes on brain and organ distribution of dual Pgp/BCRP substrates in humans.
    Medical condition: The effect of genetic polymorphisms on drug distribution will be investigated in healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-004080-39 Sponsor Protocol Number: SL-1-2016 Start Date*: 2017-03-31
    Sponsor Name:Medicinsk Forskning, Regionshospitalet Holstebro, Hospitalsenheden Vest
    Full Title: Determination of renal blood flow based on Rubidium-82 and PET-technology in healthy volunteers
    Medical condition: We wish to determine, whether PET-scans with Rubidium-82 can be used to determine renal blood flow
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-001516-19 Sponsor Protocol Number: 156-13-211 Start Date*: 2015-03-26
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization,
    Full Title: A Phase 3b, Multi-center, Open-label Trial to Evaluate the Long Term Safety of Titrated Immediate-release Tolvaptan (OPC 41061, 30 mg to 120 mg/day, Split dose) in Subjects with Autosomal Dominant ...
    Medical condition: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10036046 Polycystic kidney, autosomal dominant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed) SE (Completed) NL (Completed) BE (Completed) PL (Completed) ES (Completed) CZ (Completed) HU (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-004115-39 Sponsor Protocol Number: PoCKET Start Date*: 2018-02-08
    Sponsor Name:Nordsjællands Hospital, Department of Cardiology, Nephrology and Endocrinology
    Full Title: Subacute Effect of Tolvaptan on Total Kidney Volumen in Adult Patients with Autosomal Dominant Polycystic Kidney Disease
    Medical condition: Autosomal Dominant Polycystic Kidney DIsease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10036045 Polycystic kidney LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001809-24 Sponsor Protocol Number: JDJW-001 Start Date*: 2013-07-31
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Evaluation of urinary concentrating defects in lithium treated patients with a dDAVP test
    Medical condition: lithium-induced urinary concentrating defects (nephrogenic diabetes insipidus)
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022117 - Injury, poisoning and procedural complications 10050501 Lithium toxicity LLT
    15.0 10038359 - Renal and urinary disorders 10012600 Diabetes insipidus nephrogenic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-009426-81 Sponsor Protocol Number: CIA-GaDo Start Date*: 2009-11-10
    Sponsor Name:University Heidelberg
    Full Title: Contrast-enhanced Imaging of the Abdomen: Gadovist® vs. Dotarem® – Intraindividual comparison of 0.1mmol/kg bw gadoterate meglumine with 0.1mmol/kg bw gadobutrol for dynamic abdominal imaging in pa...
    Medical condition: patients with suspected focal liver or renal lesions
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039533 Scan NOS abdomen abnormal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002243-98 Sponsor Protocol Number: 29702 Start Date*: 2011-09-12
    Sponsor Name:Department of Nephrology, OUH, Odense, DK
    Full Title: The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity
    Medical condition: Kidney graft failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022117 - Injury, poisoning and procedural complications 10010185 Complications of transplanted kidney PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-006767-14 Sponsor Protocol Number: NL79196.018.21 Start Date*: 2022-08-24
    Sponsor Name:Amsterdam UMC
    Full Title: Alkaline Phosphatase as treatment of Ischemia Reperfusion Injury to prevent delayed graft function
    Medical condition: ischemia reperfusion injury in kidneys transplanted from donors after cardiac death
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001593-18 Sponsor Protocol Number: 958 Start Date*: 2015-06-02
    Sponsor Name:Medizinische Universiät Wien
    Full Title: A pilot study to assess the influence of drug transporters on brain and organ distribution of erlotinib in humans
    Medical condition: Investigation in volunteers only
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003336-38 Sponsor Protocol Number: MED.RES.HOS.2008.01.SM. Start Date*: 2009-02-06
    Sponsor Name:Department of Medical Research
    Full Title: The effect of Amiloride and Spironolacton on renophysiological and cardiovascular parametres in healthy patients
    Medical condition: Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019955-23 Sponsor Protocol Number: LWH 0852 Start Date*: 2010-12-29
    Sponsor Name:Liverpool Women's NHS Foundation Trust [...]
    1. Liverpool Women's NHS Foundation Trust
    2. Liverpoool Womens NHS Foundation Trust
    Full Title: To evaluate the pharmakcokinetics, tolerability and short term safety of ciprofloxacin in neonates and infants with suspected (or proven) Gram Negative Infection Open Label pilot PK study - TINN T...
    Medical condition: Pharmacokinetics of ciprofloxacin used for suspected or proven gram negative sepsis.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004311-23 Sponsor Protocol Number: HOTstudy_Thomas11 Start Date*: 2011-11-29
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: A randomised, placebo controlled trial to study the effect of heme-arginate on heme-oxygenase-1 induction and renal function in recipients of deceased donor renal transplants.
    Medical condition: Ischaemia-reperfusion injury in renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004857 10014646 End stage renal disease (ESRD) LLT
    20.0 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2009-017849-57 Sponsor Protocol Number: PCLD004 Start Date*: 2011-03-24
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Somatostatin analogues as a volume reducing treatment of polycystic livers
    Medical condition: Polycystic liver disease, due to isolated polycystic liver disease or polycystic kidney disease.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10048834 Polycystic liver disease LLT
    12.1 10048834 Polycystic liver disease PT
    12.1 10036045 Polycystic kidney LLT
    12.1 10036046 Polycystic kidney, autosomal dominant LLT
    12.1 10036048 Polycystic kidney, unspecified type LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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