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Clinical trials for Laser surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    49 result(s) found for: Laser surgery. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2006-004633-15 Sponsor Protocol Number: BAY38-9456/12496 Start Date*: 2007-01-24
    Sponsor Name:BAYER Vital GmbH
    Full Title: A randomized, double-blind, parallel group prospective pilot study to assess the effect of vardenafil on clinical outcome and on procedure duration after green light laser-ablation of the prostate ...
    Medical condition: The objective of this study is to compare the impact of vardenafil application vs. placebo on green light laser ablation of the prostate in patients presenting with benign prostate hyperplasia.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023925 Laser prostatectomy LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-004841-34 Sponsor Protocol Number: 101219 Start Date*: 2020-08-24
    Sponsor Name:Mika Harju
    Full Title: Selective laser trabeculoplasty versus eye drops for first line treatment of exfoliation ocular hypertension or glaucoma: a randomised clinical trial
    Medical condition: Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-004686-18 Sponsor Protocol Number: 539 Start Date*: 2008-02-08
    Sponsor Name:Bausch&Lomb Dr Gerhard Mann chem.-Fabrik GmbH
    Full Title: A multicenter, Investigator-Masked, Parallel Group, Randomized, Study of the Efficacy and Safety of Indomethacin 0.1% Eyedrops Compared with Ketorolac 0.5% Eyedrops in the Ocular Inflammation After...
    Medical condition: Prevention of ocular inflammation in adults patients undergoing cataract surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) PT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-004731-12 Sponsor Protocol Number: uni-koeln-1782 Start Date*: 2016-07-20
    Sponsor Name:University of Cologne
    Full Title: Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients with Retinal Detachment
    Medical condition: Primary rhegmatogenous retinal detachment (RRD) accompanied by elevated protein levels in anterior chamber fluid (laser flare value ≥15pc/ms).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003751-19 Sponsor Protocol Number: PCIA202/10 Start Date*: 2012-01-27
    Sponsor Name:PCI Biotech AS
    Full Title: An open-label, single arm, multi-centre, Phase II study to evaluate the safety and efficacy of PC-A11 with superficial and interstitial laser light application in patients with recurrent head and n...
    Medical condition: Recurrent head and neck squamous cell carcinoma (HNSCC) insuitable for surgery and radiotherapy
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10067821 Head and neck cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) NL (Prematurely Ended) LT (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001486-41 Sponsor Protocol Number: OZR-2006-01 Start Date*: 2006-09-19
    Sponsor Name:Oogziekenhuis Rotterdam
    Full Title: Effects of post-operative topical steroid versus intraoperative subconjunctival steroid injection and postoperative miotic on intraocular inflammation following cataract extraction.
    Medical condition: Post-cataract extraction ocular inflammation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2019-002591-14 Sponsor Protocol Number: CTC0128 Start Date*: 2020-05-29
    Sponsor Name:Belfast Health & Social Care Trust
    Full Title: The Fenofibrate And Microvascular Events in Type 1 diabetes Eye (FAME 1 Eye): A randomised trial to evaluate the efficacy on retinopathy and safety of fenofibrate in adults with type 1 diabetes. A...
    Medical condition: To evaluate the effects of once daily oral fenofibrate compared with placebo on clinically meaningful retinopathy progression over at least 3 years in adults with Type 1 diabetes (T1D) and existing...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-001852-11 Sponsor Protocol Number: ARG1 Start Date*: 2006-10-13
    Sponsor Name:Medical University of Vienna
    Full Title: Influence of L-Arginine on perfusion in patients receiving peripheral bypass surgery (Einfluss von L-Arginin auf die Perfusion bei Patienten mit peripheren Bypassoperationen)
    Medical condition: In general, ischemia and reperfusion are main causes for tissue damage and consequently for organ damage after surgery. Particularily, patients suffering from a peripheral occlusive disease show a ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002545-38 Sponsor Protocol Number: 68943 Start Date*: 2019-09-13
    Sponsor Name:Bispebjerg Hospital, Department of Dermatology
    Full Title: Biodistribution of ablative fractional laser-assisted topical delivery of Vismodegib in basal cell carcinomas.
    Medical condition: Basal cell carcinoma Simple nodular basal cell carcinoma at any body locations
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10004146 Basal cell carcinoma PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10066495 Basal cell carcinoma recurrent LLT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10073093 Nodular basal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-003407-34 Sponsor Protocol Number: pre-CIN Start Date*: 2021-06-01
    Sponsor Name:Oslo University Hospital
    Full Title: A randomized clinical three-arm trial comparing inflammation and cystoid macular edema for the medication regimens preoperative and postoperative topical NSAIDs to only postoperative topical NSAIDs...
    Medical condition: Cataract surgery, and the medical treatment is anti-inflammatory eye drops to treat (and prevent) intraocular inflammation and development og cystoid macular edema.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-005400-14 Sponsor Protocol Number: WONR1001 Start Date*: 2008-07-25
    Sponsor Name:Moorfields Eye Hospital NHS Foundation Trust
    Full Title: PERIOPERATIVE INTRAVITREAL TRIAMCINOLONE IN PHAKOEMULSIFICATION FOR CONCURRENT CLINICALLY SIGNIFICANT DIABETIC MACULAR OEDEMA
    Medical condition: Diabetic Maculopathy: Clinically significant macular oedema To understand the effects of intravitreal triamcinolone (IVTA) in the treatment of clinically significant macular edema (CSME) in diabet...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057915 Diabetic macular oedema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001389-18 Sponsor Protocol Number: 1 Start Date*: 2006-09-27
    Sponsor Name:Ludwig Boltzmann Institute forRetinology and Biomicroscopic Laser Surgery
    Full Title: Comparison of Combined Therapy of Intravitreal Injection of Bevacizumab and Pegaptanib versus Mono-therapy (The MAAM Study)
    Medical condition: Subjects of either gender aged > 50 years, diagnosed with subfoveal CNV secondary to AMD, a predominantly occult lesion composition, and with best corrected visual acuity of 20/40 to 20/200 in the ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004347-37 Sponsor Protocol Number: VSV2016b Start Date*: 2017-01-31
    Sponsor Name:Helsinki University Hospital
    Full Title: Femoralblock in endovenous laser
    Medical condition: venous disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002066-39 Sponsor Protocol Number: REPEXStudy Start Date*: 2013-09-04
    Sponsor Name:Azienda Ospedaliera di Reggio Emilia Arcispedale "S.Maria Nuova"/IRCCS
    Full Title: The Reggio Emilia study on bromfenac for patients with PseudoEXfoliation syndrome undergoing cataract surgery: the REPEX study
    Medical condition: Postoperative inflammation in patients with pseudoexfoliatio lentis undergoing cataract surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001093-16 Sponsor Protocol Number: DX203 Start Date*: 2013-07-16
    Sponsor Name:Oculis ehf.
    Full Title: Comparison of non-MMC trabeculectomy and dexamethasone nanoparticles eye drops with MMC trabeculectomy and Maxidex®
    Medical condition: Anti-inflammatory treatment post trabeculectomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-006066-40 Sponsor Protocol Number: OZR-2011-23 Start Date*: 2012-05-15
    Sponsor Name:The Rotterdam Eye Hospital
    Full Title: The post-cataract inflammatory reaction with combination therapy of topical steroid and NSAID.
    Medical condition: Ocular inflammatory reaction after cataract surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-001069-26 Sponsor Protocol Number: 06/45/02 Start Date*: 2009-04-06
    Sponsor Name:University of Aberdeen
    Full Title: Randomised controlled trial comparing foam sclerotherapy, alone or in combination with endovenous laser therapy, with conventional surgery as a treatment for varicose veins
    Medical condition: Varicose Veins
    Disease: Version SOC Term Classification Code Term Level
    9.1 10047013 Varicose veins of lower extremities LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012609-20 Sponsor Protocol Number: 343/09 Start Date*: 2009-09-08
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: INTRAVITREAL BEVACIZUMAB INJECTION VS. CONVENTIONAL LASER SURGERY FOR VISION-THREATENING RETINOPATHY OF PREMATURITY.
    Medical condition: AP-ROP
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038933 Retinopathy of prematurity LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001600-23 Sponsor Protocol Number: HLS02/2008 Start Date*: 2010-01-08
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Prospective, randomized, single masked pilot study on the variation of choroidal blood flow analyzed through the HRA dynamic angiography in patients treated with intravitreal injection of Selecti...
    Medical condition: Choroidal neovascularization in patients with age-related macular degeneration.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001385-16 Sponsor Protocol Number: 7 Start Date*: 2008-02-21
    Sponsor Name:Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery, Rudolf Foundation Clinic
    Full Title: Rheohemapheresis and Lutein Supplementation (xantophyll carotenoid) in the Non-Exsudative Form of Age-Related Macular Degeneration. (ReLux-AMD)
    Medical condition: Non-exsudative age-related macular degeneration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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