- Trials with a EudraCT protocol (16)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
16 result(s) found for: MSH6.
Displaying page 1 of 1.
EudraCT Number: 2020-004957-62 | Sponsor Protocol Number: ET20-093 | Start Date*: 2021-09-09 |
Sponsor Name:Centre Léon Bérard | ||
Full Title: Immunotherapy in MSI/dMMR Tumors in perioperative setting | ||
Medical condition: MSI/dMMR tumors or EBV+ gastric cancer | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: FR (Trial now transitioned) | ||
Trial results: (No results available) |
EudraCT Number: 2021-001181-38 | Sponsor Protocol Number: AuspiCiOus | Start Date*: 2021-07-29 |
Sponsor Name:Academic Medical Center | ||
Full Title: Anti-PD-1, Capecitabine, and Oxaliplatin for the first-line treatment of dMMR esophagogastric cancer (AuspiCiOus-dMMR): a proof-of-principle study | ||
Medical condition: Gastroesophageal cancer | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: NL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2018-004712-22 | Sponsor Protocol Number: D18-02 | Start Date*: 2019-06-13 | |||||||||||
Sponsor Name:GERCOR | |||||||||||||
Full Title: Peri-operative association of immunotherapy (pre-operative association of nivolumab and ipilimumab, post-operative nivolumab alone) in localized microsatellite instability (MSI) and/or deficient mi... | |||||||||||||
Medical condition: oeso-gastric adenocarcinoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-003548-35 | Sponsor Protocol Number: MesaCAPP | Start Date*: 2017-03-10 | |||||||||||
Sponsor Name:Medical University of Vienna | |||||||||||||
Full Title: Mesalamine for Colorectal Cancer Prevention Program in Lynch syndrome | |||||||||||||
Medical condition: Colorectal Cancer Prevention in Lynch syndrome | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Prematurely Ended) NL (Prematurely Ended) SE (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-003011-55 | Sponsor Protocol Number: MesaCAPP | Start Date*: 2020-07-23 | ||||||||||||||||
Sponsor Name:Karolinska Institute | ||||||||||||||||||
Full Title: Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome | ||||||||||||||||||
Medical condition: Lynch Syndrome, which is increasing the risk of developing colorectal cancer. | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: SE (Trial now transitioned) DK (Trial now transitioned) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2013-005086-40 | Sponsor Protocol Number: J1214 | Start Date*: 2014-05-21 | |||||||||||
Sponsor Name:Sidney kimmel Comprehensive Cancer Center at Johns Hopkins | |||||||||||||
Full Title: A multi-institutional open label, trial evaluating the efficacy of Gemcitabine and Docetaxel in patients with relapsed or refractory metastatic colorectal adenocarcinoma with methylated CHFR and/or... | |||||||||||||
Medical condition: relapsed or refractory metastatic colorectal adenocarcinoma with methylation of CHFR and/or microsatellite instability | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-004126-13 | Sponsor Protocol Number: CaPture | Start Date*: 2020-10-06 |
Sponsor Name:University Leipzig | ||
Full Title: Cabozantinib treatment in a phase II study for patients with hepatocellular carcinoma (HCC) refractory to PD-1 or PD-L1 inhibitors | ||
Medical condition: Hepatocellular carcinoma | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DE (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2022-003289-18 | Sponsor Protocol Number: 219369 | Start Date*: 2023-03-10 | ||||||||||||||||
Sponsor Name:GlaxoSmithKline Research & Development Limited | ||||||||||||||||||
Full Title: A Phase 2, Single-Arm, Open-Label Study with Dostarlimab Monotherapy in Participants with Untreated Stage II/III dMMR/MSI-H Locally Advanced Rectal Cancer | ||||||||||||||||||
Medical condition: Untreated Stage II/III dMMR/MSI-H locally advanced rectal cancer | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) IT (Trial now transitioned) NL (Trial now transitioned) ES (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-002442-72 | Sponsor Protocol Number: C17-01 | Start Date*: 2017-10-23 | |||||||||||
Sponsor Name:GERCOR | |||||||||||||
Full Title: RECIST 1.1 and iRECIST evaluation for patients with deficient MMR and/or MSI Metastatic Colorectal Cancer treated with nivolumab and ipilimumab. A GERCOR open-label phase II study NIPICOL C17-01 | |||||||||||||
Medical condition: Patients with deficient MMR and/or MSI Metastatic Colorectal Cancer treated with nivolumab and ipilimumab | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-000370-10 | Sponsor Protocol Number: POLEMCCR4673 | Start Date*: 2018-05-09 | |||||||||||
Sponsor Name:The Royal Marsden NHS Foundation Trust | |||||||||||||
Full Title: Avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III dMMR or POLE exonuclease domain mutant colon cancer: A phase III randomised study. | |||||||||||||
Medical condition: Colon cancer stage III | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-004575-49 | Sponsor Protocol Number: FFCD-1603 | Start Date*: 2017-07-11 |
Sponsor Name:Federation Francophone de Cancerologie Digestive | ||
Full Title: MULTICENTER RANDOMIZED PHASE II STUDY COMPARING THE EFFECTIVENESS AND TOLERANCE OF AVELUMAB VERSUS STANDARD 2nd LINE TREATMENT CHEMOTHERAPY IN PATIENTS WITH COLORECTAL METASTATIC CANCER WITH MICROS... | ||
Medical condition: COLORECTAL METASTATIC CANCER WITH MICROSATELLITE INSTABILITY (MSI) | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: FR (Trial now transitioned) | ||
Trial results: (No results available) |
EudraCT Number: 2012-002206-52 | Sponsor Protocol Number: CD-ON-MEDI4736-1108 | Start Date*: 2012-12-05 |
Sponsor Name:MedImmune | ||
Full Title: A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4736 in Subjects with Advanced Solid Tumors | ||
Medical condition: Advanced Solid Tumors | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: BE (Completed) GB (Completed) DK (Prematurely Ended) | ||
Trial results: View results |
EudraCT Number: 2014-000411-14 | Sponsor Protocol Number: 6639 | Start Date*: 2014-07-17 | |||||||||||
Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust | |||||||||||||
Full Title: A randomised double blind dose non-inferiority trial of a daily dose of 600mg versus 300mg versus 100mg of enteric coated aspirin as a cancer preventive in carriers of a germline pathological misma... | |||||||||||||
Medical condition: Lynch Syndrome also known as HNPCC (non hereditary non polyposis colorectal cancer). | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FI (Completed) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-008922-55 | Sponsor Protocol Number: GEIS20 | Start Date*: 2009-06-04 | |||||||||||
Sponsor Name:Grupo Español de Investigación en Sarcomas | |||||||||||||
Full Title: ENSAYO FASE II ALEATORIZADO, ABIERTO, MULTICÉNTRICO Y PROSPECTIVO DE DOXORRUBICINA vs TRABECTEDINA Y DOXORRUBICINA EN PRIMERA LÍNEA DE PACIENTES CON SARCOMA DE PARTES BLANDAS AVANZADOS NO OPERABLES... | |||||||||||||
Medical condition: Sarcoma de partes blandas avanzados no operables y/o metastásicos | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Prematurely Ended) PT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-005108-89 | Sponsor Protocol Number: VHIO17002 | Start Date*: 2019-01-25 | |||||||||||
Sponsor Name:Vall d’Hebron Institute of Oncology (VHIO) | |||||||||||||
Full Title: Basket of Baskets: A Modular, Open-label, Phase II, Multicentre Study To Evaluate Targeted Agents in Molecularly Selected Populations With Advanced Solid Tumors. | |||||||||||||
Medical condition: Subjects with advanced solid tumor | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Trial now transitioned) SE (Trial now transitioned) DE (Trial now transitioned) GB (GB - no longer in EU/EEA) FR (Trial now transitioned) ES (Ongoing) IT (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-003243-21 | Sponsor Protocol Number: XL092-303 | Start Date*: 2022-10-06 | |||||||||||
Sponsor Name:Exelixis, Inc. | |||||||||||||
Full Title: A Randomized Open-Label Phase 3 Study of XL092 + Atezolizumab vs Regorafenib in Subjects with Metastatic Colorectal Cancer | |||||||||||||
Medical condition: Metastatic colorectal cancer (CRC) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) FR (Trial now transitioned) BE (Trial now transitioned) PT (Trial now transitioned) | |||||||||||||
Trial results: (No results available) |
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