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Clinical trials for Methylphenidate

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    92 result(s) found for: Methylphenidate. Displaying page 1 of 5.
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    EudraCT Number: 2010-023992-24 Sponsor Protocol Number: MEMAP1 Start Date*: 2011-08-26
    Sponsor Name:University of Leipzig
    Full Title: International randomised double-blind placebo-controlled study on the initial treatment of acute mania with methylphenidate
    Medical condition: acute mania and hypomania (ICD-10: F30.0, F30.1, F31.0, F31.1)
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10000852 Acute mania LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) BE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-004664-46 Sponsor Protocol Number: melmet Start Date*: 2008-07-29
    Sponsor Name:No Sponsor
    Full Title: Influence of methylphenidate on sleep and circadian rhythm in children with Attention-Deficit/Hyperactivity Disorder (ADHD)
    Medical condition: Sleep disorders in Attention-Deficit/ Hyperactivity Disorder (ADHD)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003660-11 Sponsor Protocol Number: 74817 Start Date*: Information not available in EudraCT
    Sponsor Name:Accare
    Full Title: Do effects of methylphenidate decline after long-term use? A double-blind, placebo-controlled cross-over study of effects of methylphenidate on cognitive functioning and real world behavior in trea...
    Medical condition: Attention Deficit Hyperactivity Disorder (ADHD)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005146-55 Sponsor Protocol Number: VUB-HUIS-002 Start Date*: 2016-01-27
    Sponsor Name:Vakgroep Huisartsgeneeskunde Vrije Universiteit Brussel
    Full Title: The effect of methylphenidate (Ritalin®) on the severity of stuttering.
    Medical condition: Stuttering
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003418-15 Sponsor Protocol Number: SSP Start Date*: 2012-10-23
    Sponsor Name:Medizinische Universität Wien
    Full Title: Methylphenidate modified release as treatment option of MS-associated fatigue. A single-center randomized double-blind placebo-controlled trial.
    Medical condition: Fatigue is a very common symptom in multiple sclerosis. Its management comprises nonpharmacologic approaches like exercise, cooling procedures and energy conservation programs and as second step ph...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001950-33 Sponsor Protocol Number: 15/0592 Start Date*: 2018-01-19
    Sponsor Name:UCL
    Full Title: Methylphenidate versus placebo for fatigue in advanced cancer (MePFAC)
    Medical condition: Cancer-related fatigue
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10016256 Fatigue PT
    Population Age: Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-004206-26 Sponsor Protocol Number: VUB-HUIS-001 Start Date*: 2014-02-10
    Sponsor Name:Vakgroep Huisartsgeneeskunde VUB
    Full Title: The effect of methylphenidate (Ritalin ®) on the severity of stuttering.
    Medical condition: stuttering
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004053-76 Sponsor Protocol Number: NL73102.018.20 Start Date*: 2020-12-10
    Sponsor Name:Amsterdam UMC [...]
    1. Amsterdam UMC
    2. 's Heeren Loo
    Full Title: Effectiveness of methylphenidate in children and adults with Smith Magenis syndrome and attention-deficit/hyperactivity disorder: An N-of-1 series
    Medical condition: Smith Magenis syndrome
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000502-40 Sponsor Protocol Number: RHM CAN0380 Start Date*: 2005-05-13
    Sponsor Name:Southampton University Hospitals Trust
    Full Title: A thematic analysis of semi-structured interviews using a phenomenological approach into palliative care patients experiences of change in "fatigue" following treatment with methylphenidate – an ex...
    Medical condition: Patients with cancer in palliative stage of their illness. Suffering from fatigue with or without decreased concentration, depression or drowsiness, who feel their fatigue is severe enough to decre...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002096-14 Sponsor Protocol Number: MF115 Start Date*: 2015-08-28
    Sponsor Name:Sahlgrenska University Hospital
    Full Title: Examine whether treatment with methylphenidate facilitates work rehabilitation for persons with long-term pain and mental fatigue after traumatic brain injury.
    Medical condition: Long-term pain and mental fatigue after traumatic brain injury and work rehabilitation.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005073-28 Sponsor Protocol Number: ParKMetil/001 Start Date*: 2021-12-28
    Sponsor Name:Universidad Rey Juan Carlos
    Full Title: Double-blind, randomized, crossover design for evaluation of efficacy and safety of methylphenidate in cognition in patients with Parkinson's disease using electrophysiological measures
    Medical condition: Cognition
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012643-42 Sponsor Protocol Number: 28119 Start Date*: 2010-01-06
    Sponsor Name:University Medical Center Groningen
    Full Title: Freezing of gait in Parkinson's disease: in search of the underlying mechanism and the application of a new treatment option
    Medical condition: Parkinson's disease, in particular the symptom Freezing of Gait
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000925-60 Sponsor Protocol Number: R1/11 Start Date*: 2011-10-18
    Sponsor Name:Kungälv Hospital
    Full Title: Effect of treatment with methylphenidate on mental fatigue (“brain fatigue”) and pain on persons who have suffered a traumatic brain injury or whip lash injury – a pilot study.
    Medical condition: Mental fatigue after traumatic brain injury or whip-lash injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004815-22 Sponsor Protocol Number: INDICES/WP2/01 Start Date*: 2012-01-24
    Sponsor Name:Research Institute of Biological Psychiatry Sct. Hans
    Full Title: Individualised drug therapy based on pharmacogenomics: focus on carboxylesterase 1 (CES1)
    Medical condition: Healthy volunteers with special genotypes
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004848 10053349 Pharmacokinetic study LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002002-20 Sponsor Protocol Number: 2014METAL1 Start Date*: 2015-06-10
    Sponsor Name:UMCG
    Full Title: A multicentre randomized double-blind placebo controlled discontinuation trial of methylphenidate
    Medical condition: attention-deficit/hyperactivity disorder
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000992-18 Sponsor Protocol Number: 12-016 Start Date*: 2014-09-26
    Sponsor Name:UMC Utrecht
    Full Title: Proactive versus reactive inhibition in ADHD: Genetics, neurobiology and pharmacology
    Medical condition: Attention-Deficit Hyperactivity Disorder (ADHD)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000492-17 Sponsor Protocol Number: NL39440.029.10 Start Date*: 2012-10-29
    Sponsor Name:Afdeling Klinische Neuropsychologie Vrije Universiteit Amsterdam
    Full Title: The Effects of Long-acting Methylphenidate on Academic Activity and Related Constructs in Children with ADHD: A Randomised Placebo Controlled Trial
    Medical condition: Attention-deficit hyperactivity disorder (ADHD)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004298-20 Sponsor Protocol Number: MAMCAC02102014 Start Date*: 2015-02-03
    Sponsor Name:Stockholm Centre for Dependency Disorders
    Full Title: The effect of methylphenidate on executive functioning in amphetamine dependent individuals with ADHD
    Medical condition: Amphetamine dependence
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002249-35 Sponsor Protocol Number: mkjf001 Start Date*: 2006-10-26
    Sponsor Name:Addiction Center Stockholm
    Full Title: Clinical trial of sustained release methylphenidate for Attention-Deficit-Hyperactivity-Disorder (ADHD) in adult criminal offenders with amphetamine addiction
    Medical condition: 54 male prison inmates (27 in each treatment condition) that meet the DSM-IV criteria for amphetamine addiction and for ADHD and who are servicing their prison sentence are recruited.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-001844-36 Sponsor Protocol Number: 1 Start Date*: 2017-09-13
    Sponsor Name:Odense University Hospital
    Full Title: MethylphenIdate for fatigue in haematological cancer. A randomized, double-blind, placebo-controlled, CROssover trial - the MICRO trial
    Medical condition: Cancer related fatigue in patients with haematological cancer disease
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10066564 Chronic fatigue LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
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