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Clinical trials for Muscle relaxation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    50 result(s) found for: Muscle relaxation. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2013-002164-53 Sponsor Protocol Number: 20130513 Start Date*: 2013-12-02
    Sponsor Name:Medizinische Universität Wien, Abteilung für Allgemeine Anästhesie und Intensivmedizin
    Full Title: The reversed isolated forearm technique to regionally reverse rocuronium induced muscle relaxation – a pilot study
    Medical condition: To evaluate the feasibility of regionally reversing a rocuronium induced muscle relaxation and to determine the dose of sugammadex that is necessary to reach a train of four (TOF) ratio ≥ 0.9. To d...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003737-19 Sponsor Protocol Number: CHUB-ITF-sevo-propofol Start Date*: 2023-01-10
    Sponsor Name:CHU Brugmann
    Full Title: Influence of sevoflurane and propofol on maximum muscular strength, speed of contraction and relaxation, in humans: A pilot study.
    Medical condition: Impact of anesthetic drugs on neuromuscular transmission
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-005010-40 Sponsor Protocol Number: 30082007 Start Date*: 2008-03-13
    Sponsor Name:Univ.-Prof. Dr. Volker Wenzel
    Full Title: Arginin Vasopressin im fortgeschrittenen vasodilatorischen Schock: Ein Dosisvergleich 2 vs. 4 IU/h
    Medical condition: 5. Einschlusskriterien 5.1. Patienten mit vasodilatorischem Schock aufgrund: a) Sepsis [Definitionen gemäss den Empfehlungen der ACCP/SCCM (12)] b) SIRS [Definitionen gemäss den Empfehlungen der ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021118 Hypotonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001597-16 Sponsor Protocol Number: none Start Date*: 2018-07-18
    Sponsor Name:Sitnikova Victoria
    Full Title: Efficacy of botulinum toxin in treating temporomandibular disorders
    Medical condition: Patients are diagnosed TMD (temporomandibular disorder) according to DC/TMD international consortium: myalgia, local myalgia, myofascial pain, myofascial pain with referral.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10028323 Muscle pains HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000462-62 Sponsor Protocol Number: Statex1 Start Date*: 2015-09-23
    Sponsor Name:Radboud university medical centre
    Full Title: The effects of statins on skeletal muscle mitochondria: is exercise the medicine?
    Medical condition: Asymp and symp statin users will undergo baseline measurements of skeletal muscle mitochondrial function and muscle function after which they will be switched to a single-blind placebo intervention...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-015771-27 Sponsor Protocol Number: V3 Start Date*: 2010-01-21
    Sponsor Name:Medizinische Universität Wien, Univ.Klinik für Notfallmedizin
    Full Title: Requirement of Skeletal Muscle Paralysis in Hypothermic Patients after Cardiac Arrest. A pilot study
    Medical condition: skeletal muscle paralysis in hypothermic patients after cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-002147-18 Sponsor Protocol Number: ABR49503 Start Date*: 2015-07-02
    Sponsor Name:Academic Medical Center
    Full Title: A randomized controlled double-blinded trial comparing the effect of on Demand ROcuronium boluses vs continuous infusion on rating of surgical and anesthesia conditions and need for reversal in Pat...
    Medical condition: oesophageal carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000029-29 Sponsor Protocol Number: 95105003 Start Date*: 2018-12-11
    Sponsor Name:VU University Medical Center
    Full Title: Extra energy for hearts with a genetic defect: ENERGY trial
    Medical condition: Hypertrophic cardiomyopathy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001155-22 Sponsor Protocol Number: Lap2014NMB Start Date*: 2014-05-22
    Sponsor Name:Mona Ring Gätke
    Full Title: Muscle relaxation during open upper abdominal surgery -can the surgical conditions be optimized? (The laparotomy study)
    Medical condition: The aim of the study is to investigate if intense NMB improves surgical conditions during operation in patients scheduled for elective open upper abdominal surgery.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10023697 Laparotomy & drainage LLT
    17.0 100000004865 10051777 Staging laparotomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-012815-16 Sponsor Protocol Number: ROSANNA Start Date*: 2010-03-18
    Sponsor Name:Technische Universität München
    Full Title: Dosis-Wirkungsstudie von Rocuronium unter Propofol-Anästhesie (Rocuronium Dose Finding Study after single shot or steady state propofol anesthesia)
    Medical condition: Rocuronium dose finding study; evaluation of effective doses (ED 50 and ED 95) of rocuronium after single shot or steady state propofol anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029315 Neuromuscular blockade LLT
    9.1 10029315 Neuromuscular blockade PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001965-17 Sponsor Protocol Number: AITT2013/5 Start Date*: 2013-09-26
    Sponsor Name:Debreceni Egyetem Orvos- és Egészségtudományi Centrum Aneszteziológiai és Intenzív Terápiás Tanszék
    Full Title: Incidence of postoperative residual neuromuscular blockade following the administration of rocuronium: A randomized placebo controlled study.
    Medical condition: The effect of sugammadex and neostigmin on postoperative residual neuromuscular blockade will be investigated, therefore the patients suffering from various conditions undergoing surgery in general...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10042613 - Surgical and medical procedures 10057286 Neuromuscular blockade reversal PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001732-21 Sponsor Protocol Number: MET001 Start Date*: 2013-09-06
    Sponsor Name:Centre d'Etude des Cellules Souches (CECS)
    Full Title: A randomized, double blind, placebo-controlled phase II study of metformin in myotonic dystrophy type 1 patients
    Medical condition: Myotonic dystrophy type 1 (DM1) also known as Steinert disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-001886-33 Sponsor Protocol Number: MK-8616-076-00 Start Date*: 2012-10-30
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: Randomized, Controlled, Parallel Group, Double Blind Trial to Compare the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures Using a 2x2 Fact...
    Medical condition: Patients undergoing elective in-patient laparoscopic cholecystectomy procedures under general anesthesia with neuromuscular relaxation and active reversal of neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10018061 General anesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) FI (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002961-21 Sponsor Protocol Number: NS918 Start Date*: 2018-11-09
    Sponsor Name:UZ Leuven
    Full Title: The effect of deep neuromuscular block and reversal with sugammadex on surgical conditions and perioperative morbidity in shoulder surgery using a deltopectoral approach
    Medical condition: Subject undergoing elective or semi-elective surgery to the gleno-humeral joint or the proximal humerus using a deltoideo-pectoral approach.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003033-42 Sponsor Protocol Number: EURO-RELAX Start Date*: 2020-01-28
    Sponsor Name:INSTITUTO DE INVESTIGACIÓN SANITARIA LA FE
    Full Title: The impact of deep versus standard muscle relaxation on intra-operative safety during laparoscopic surgery: a multicenter strategy study – EURO RELAX STUDY
    Medical condition: Intra-operative adverse events during laparoscopic surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003385-24 Sponsor Protocol Number: 2815 Start Date*: 2016-09-28
    Sponsor Name:GGZ inGeest, parner VUmc
    Full Title: The Recall-study: Rivastigmine for ECT-induced Cognitive Adverse effects in Late Life Depression: a multicenter, randomized, double-blind, placebo-controlled, crossover trial
    Medical condition: Interictal delirium during electric convulsive therapy- course
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001164-29 Sponsor Protocol Number: NMBDK2013 Start Date*: 2013-05-15
    Sponsor Name:Department of anesthesiology
    Full Title: Optimizing surgical conditions: Intraabdominal distance during gynecologic laparoscopic surgery with and without muscle relaxation (The measurement study)
    Medical condition: To investigate if deep neuromucular blockade improves intraabdominal volume compared to no neuromuscular blockade in patients scheduled for gynecologic laparoscopic surgery with pneumoperitoneum 12...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10023692 Laparoscopically assisted hysterectomy LLT
    14.1 100000004865 10023691 Laparoscopic sterilization LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005050-47 Sponsor Protocol Number: 19.4.304 Start Date*: 2006-01-24
    Sponsor Name:NV Organon
    Full Title: A multi-center, parallel-group, comparative trial evaluating the efficacy, pharmacokinetics and safety of Org 25969 in subjects with normal or impaired renal function.
    Medical condition: Not Applicable
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-003787-51 Sponsor Protocol Number: NMBDK2012 Start Date*: 2012-10-22
    Sponsor Name:Mona Ring Gätke
    Full Title: Recovery after laparoscopic hysterectomy with deep neuromuscular blockade and low intraabdominal pressure
    Medical condition: The pain study: To evaluate the importance of deep neuromuscular blockade (NMB) and low intraabdominal pressure in laparoscopic hysterectomy considering postoperative pain, nausea, consumption of ...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003623-29 Sponsor Protocol Number: 63227.091.17 Start Date*: 2018-03-27
    Sponsor Name:Radboudumc
    Full Title: MRI measurement of the effects of moderate versus deep neuromuscular blockade on the abdominal working space during laparoscopic surgery in a prospective cohort study.
    Medical condition: We will investigate the effect of deep neuromuscular blockade on the abdominal working space. We will include patients undergoing laparoscopic surgery, including laparoscopic donor nephrectomy, lap...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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