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Clinical trials for Nicotinamide

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    23 result(s) found for: Nicotinamide. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2004-005034-39 Sponsor Protocol Number: Start Date*: 2005-05-17
    Sponsor Name:Queen Elizabeth Hospital
    Full Title: Nicotinamide,vitamin B3, metabolic pathways in patients with early idiopathic parkinson's disease
    Medical condition: Idiopathic Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-005637-37 Sponsor Protocol Number: ASF-1057-206 Start Date*: 2007-02-28
    Sponsor Name:Astion Danmark A/S
    Full Title: Comparative, placebo controlled, double-blind efficacy and safety study in patients with seborrhoeic dermatitis comparing a topical cream containing 2% Nicotinamide combined with either 0%, 0.5% or...
    Medical condition: Seborrhoeic Dermatitis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002245-11 Sponsor Protocol Number: NAM2 Start Date*: 2019-01-16
    Sponsor Name:UMC Utrecht
    Full Title: Assessing penetration of high dose Nicotinamide (Vitamin B3) in synovial fluid
    Medical condition: Juvenile Idiopathic Arthritis (JIA)
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000743-66 Sponsor Protocol Number: NAMCHEM Start Date*: 2018-07-10
    Sponsor Name:FONDAZIONE LUIGI MARIA MONTI IDI-IRCCS
    Full Title: Multicenter, interventional, single-arm, phase IV study on specific metabolic and genomic profiles as predictors of nicotinamide efficacy in cutaneous squamous cell carcinoma prevention
    Medical condition: Cutaneous squamous-cell carcinoma (cSCC) is the most common age-associated malignancy that usually arises from the lesion actinic keratosis (AK) or grows de novo in photoexposed areas.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059813 Spinocellular carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001276-15 Sponsor Protocol Number: PI2020_843_0027 Start Date*: 2020-06-18
    Sponsor Name:CHU Amiens-Picardie
    Full Title: Does high-dose vitamin B3 supplementation prevent major adverse kidney events during septic shock? A multicenter randomized controlled study.
    Medical condition: adverse kidney events during septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-002163-17 Sponsor Protocol Number: 15-138 Start Date*: 2018-10-25
    Sponsor Name:RWTH Aachen University represented by the Center for Translational & Clinical Research Aachen (CTC-A)
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTRE STUDY OF THE EFFICACY AND SAFETY OF NICOTINAMIDE IN PATIENTS WITH FRIEDREICHS ATAXIA.
    Medical condition: Friedreich Ataxia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended) GB (GB - no longer in EU/EEA) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2016-003643-10 Sponsor Protocol Number: NAM Start Date*: Information not available in EudraCT
    Sponsor Name:UMC Utrecht
    Full Title: Modulating regulatory T cell function in JIA with Vitamin B3 (nicotinamide) treatment
    Medical condition: Juvenile idiopathic arthritis (JIA)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002744-27 Sponsor Protocol Number: CR01849 Start Date*: 2011-11-01
    Sponsor Name:Imperial College
    Full Title: Pharmacodynamic Studies of a Histone Deacetylase Inhibitor in FRDA
    Medical condition: Friedreich’s ataxia
    Disease: Version SOC Term Classification Code Term Level
    14.0 10010331 - Congenital, familial and genetic disorders 10017374 Friedreich's ataxia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-004673-17 Sponsor Protocol Number: PHRC IR08 - Pr. FOURNIER Start Date*: 2009-03-23
    Sponsor Name:CHU d'Amiens
    Full Title: Comparaison du nicotinamide et du sevelamer hydrochloride sur le contrôle de la phosphatémie des hémodialysés chroniques
    Medical condition: Ostéodystrophie rénale
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000488-95 Sponsor Protocol Number: 6520-9961-04 Start Date*: 2013-08-28
    Sponsor Name:MEDICE Arzneimittel Pütter GmbH & Co. KG
    Full Title: Efficacy and tolerability of nicotinamide as add-on therapy compared to placebo in dialysis-dependent patients with hyperphosphatemia
    Medical condition: Dialysis-dependent patients with hyperphosphatemia
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004861 10020712 Hyperphosphatemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) AT (Completed) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003984-24 Sponsor Protocol Number: EPIsoDE_01 Start Date*: 2020-11-17
    Sponsor Name:Central Institute of Mental Health
    Full Title: A phase II randomized, double-blind, active placebo-controlled parallel group trial to examine the efficacy and safety of psilocybin in treatment-resistant major depression
    Medical condition: Treatment-Resistant Depressive Episode or Treatment-Resistant Recurrent Depressive Disorder of moderate to severe degree withoutpsychotic features
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000720-19 Sponsor Protocol Number: IDI01/2020 Start Date*: 2020-07-22
    Sponsor Name:IDI FARMACEUTICI SRL
    Full Title: A prospective, randomized, multicenter, open- label, two-arm and parallel-group Study to evaluate the efficacy and safety of Nicotinamide DS compared to Ciclopirox olamine cream at 1% in patients a...
    Medical condition: Patients affected by seborrheic dermatitis.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10040785 - Skin and subcutaneous tissue disorders 10039793 Seborrhoeic dermatitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021886-63 Sponsor Protocol Number: RD2010-48 Start Date*: 2011-07-14
    Sponsor Name:East and North Hertfordshire NHS Trust [...]
    1. East and North Hertfordshire NHS Trust
    2.
    Full Title: A trial of Prostate Radiotherapy in Conjunction with Carbogen and Nicotinamide (PROCON)
    Medical condition: Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015821-34 Sponsor Protocol Number: 6520-9961-03 Start Date*: 2010-07-13
    Sponsor Name:MEDICE Arzneimittel GmbH & Co. KG
    Full Title: Dosisfindungsstudie zu Nicotinamid bei dialysepflichtigen Patienten mit Hyperphosphatämie
    Medical condition: Hyperphosphatämie bei dialysepflichtigen Patienten
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004184-79 Sponsor Protocol Number: NIAD-01 Start Date*: 2013-05-01
    Sponsor Name:Dermal Laboratories Limited
    Full Title: A placebo controlled evaluation of a developmental gel for the treatment of atopic eczema
    Medical condition: The medical condition to be investigated in this study is atopic eczema, also known as atopic dermatitis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10003641 Atopic eczema LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-016591-68 Sponsor Protocol Number: 09.15 Start Date*: 2009-12-22
    Sponsor Name:Odense University Hospital
    Full Title: Placebo-controlled trial investigating the effect of Vitamin K3-lotion for the treatment of cetuximab induced folliculitis
    Medical condition: Cancer patients experiencing folliculitis due to treatment with cetuximab
    Disease: Version SOC Term Classification Code Term Level
    12.0 10061451 Colorectal cancer LLT
    12.0 10067821 Head and neck cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002594-28 Sponsor Protocol Number: APHP200036 Start Date*: 2022-10-05
    Sponsor Name:ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (AP-HP)
    Full Title: Graft Acute kidney injury: vitamin B3 to facilitate renal Recovery In the Early Life of a transplant
    Medical condition: Patients with end-stage renal failure treated with extrarenal purification (hemodialysis using a catheter or a fistula, or peritoneal dialysis), registered on the national kidney donation waiting l...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003713-32 Sponsor Protocol Number: A5641009 Start Date*: 2005-11-29
    Sponsor Name:Pfizer Ltd
    Full Title: A phase II, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of UK-500,001 Dry Powder for Inhalation (DPI) in adults with moderate to severe Ch...
    Medical condition: Chronic obstructive pulmonary disease (COPD).
    Disease: Version SOC Term Classification Code Term Level
    10009033
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000756-42 Sponsor Protocol Number: MEX0111 Start Date*: Information not available in EudraCT
    Sponsor Name:Dompé s.p.a.
    Full Title: A phase 2, multicentre, single arm, pilot study to assess the efficacy and the safety of 150 mg twice a day oral DF2156A in patients with active bullous pemphigoid.
    Medical condition: active bullous pemphigoid
    Disease: Version SOC Term Classification Code Term Level
    14.0 10040785 - Skin and subcutaneous tissue disorders 10006567 Bullous pemphigoid LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000969-37 Sponsor Protocol Number: AN-SCD1121 Start Date*: 2007-10-05
    Sponsor Name:Anthera Pharmaceuticals Incorporated
    Full Title: IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome (Dose Escalation Study: Varespladib Infusion [A-001] for the Prevention of Acute Chest Syndrome in At-Risk ...
    Medical condition: Acute Chest Syndrome (ACS) in At-Risk patients with Sickle Cell Disease (SCD) and Vaso-occlusive Crisis (VOC)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051895 Acute chest syndrome LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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