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Clinical trials for PDT

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43839   clinical trials with a EudraCT protocol, of which   7280   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    122 result(s) found for: PDT. Displaying page 1 of 7.
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    EudraCT Number: 2005-002875-34 Sponsor Protocol Number: CL-070-II-02 Start Date*: Information not available in EudraCT
    Sponsor Name:IDEA AG
    Full Title: Safety and efficacy of IDEA-070 for the treatment of pain and inflammation induced by photodynamic therapy of actinic keratosis
    Medical condition: Patients suffering from actinic keratosis to be treated with PDT
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003555-13 Sponsor Protocol Number: AK 03 Start Date*: 2006-03-10
    Sponsor Name:photonamic GmbH & Co. KG
    Full Title: PD P 506 A or its placebo in combination with red light for photodynamic therapy of mild to moderate actinic keratosis
    Medical condition: Actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2023-000126-29 Sponsor Protocol Number: SZÚ/00127/2023 Start Date*: 2023-04-21
    Sponsor Name:Státní zdravotní ústav
    Full Title: Pilot Study of Combined PDT and SDT Efficacy In Vivo in Human Volunteers for Application in Hygiene and Clinical Practice
    Medical condition: Antimicrobial efficacy of combined PDT and SDT on the skin
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004403-13 Sponsor Protocol Number: PDT002/12 Start Date*: 2013-08-27
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik für Dermatologie
    Full Title: Placebo-controlled cross-over study on the efficacy of a non-steroidal antirheumatic drug for pain reduction during photodynamic therapy of actinic keratoses
    Medical condition: actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004604-31 Sponsor Protocol Number: PCCE201/08 Start Date*: 2008-10-28
    Sponsor Name:Photocure ASA
    Full Title: A randomized phase II dose-finding study of hexaminolevulinate (HAL) photodynamic therapy (PDT) in patients with low-grade cervical intraepithelial neoplasia.
    Medical condition: Low grade cervical intraepithelial neoplasia (CIN)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066238 Cervical low grade squamous intraepithelial lesion LLT
    Population Age: Adults Gender: Female
    Trial protocol: DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-000459-88 Sponsor Protocol Number: PDT08 Start Date*: 2008-12-09
    Sponsor Name:Univ.-Prof. Dr. Hans F. Merk, Dept. of Dermatology, University Hospital, RWTH Aachen University
    Full Title: Prospective, randomized study of the efficacy of photodynamic therapy in actinic keratosis
    Medical condition: We treat patients with superficial actinic keratosis grade I-II on the face or scalp.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005015-13 Sponsor Protocol Number: PC T405/05 Start Date*: 2006-02-16
    Sponsor Name:PhotoCure ASA
    Full Title: A multicenter, double blind, vehicle-controlled, randomized study of photodynamic therapy (PDT) with Metvix®160 mg/g cream and Aktilite CL128 LED light in patients with multiple actinic keratoses o...
    Medical condition: actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-000475-25 Sponsor Protocol Number: SPON489-07 Start Date*: 2009-11-10
    Sponsor Name:Cardiff University
    Full Title: Randomised, controlled, double-blind, parallel group clinical trial evaluating the efficacies and safety of methyl-aminolevulinate photodynamic therapy and intense pulsed light, administered as pl...
    Medical condition: Mild to moderate acne vulgaris in adult patients.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002663-42 Sponsor Protocol Number: TFDTRASP Start Date*: 2015-11-13
    Sponsor Name:Clínica Universidad de Navarra/Universidad de Navarra
    Full Title: RANDOMISED PILOT STUDY TO ASSESS THE CLINICAL EFFICACY OF DAYLIGHT PHOTODYNAMIC THERAPY WITH METHYL AMINOLEVULINATE CREAM (METVIX?), (MAL-PDT), IN THE PREVENTION OF ACTINIC KERATOSIS AND NON MELANO...
    Medical condition: Actinic Keratosis (AK) are histologically characterized by the proliferation of keratinocytes with atypical cytology in the epidermis. One of the main risk factors for its occurrence is immunosuppr...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-023903-91 Sponsor Protocol Number: PCCE203/10 Start Date*: Information not available in EudraCT
    Sponsor Name:Photocure ASA
    Full Title: A randomized phase II dose-finding study of hexaminolevulinate (HAL) photodynamic therapy (PDT) in patients with low/moderate-grade cervical intraepithelial neoplasia (CIN1 or 2).
    Medical condition: Patients with low/moderate-grade cervical intraepithelial neoplasia (CIN1 or 2).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10066238 Cervical low grade squamous intraepithelial lesion LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) SK (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-004262-16 Sponsor Protocol Number: PDTMohs05 Start Date*: 2006-01-20
    Sponsor Name:Guy's & St Thomas' NHS Foundation Trust
    Full Title: A trial comparing Metvix® photodynamic therapy (PDT) followed by Mohs micrographic surgery with Mohs micrographic surgery alone for the treatment of basal cell carcinoma (BCC)
    Medical condition: Basal cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10042503 Superficial basal cell carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004866-17 Sponsor Protocol Number: 01/2005 Start Date*: 2007-04-03
    Sponsor Name:Dept Medicine I, Paracelsus Med. Univ. Landeskrankenanstalten Salzburg / SALK
    Full Title: An Open-label, single arm Phase II Trial of Photodynamic Therapy using Foscan for non-curatively-resectable bile duct carcinoma
    Medical condition: Nonresectable hilar or extrahepatic bile duct carcinoma in clinical stage MO ( without liver or peritoneal metastases according to clinical or surgical staging)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002466-11 Sponsor Protocol Number: version125/05/05 Start Date*: 2006-01-03
    Sponsor Name:King's College Hospital
    Full Title: A Pilot Study to Examine the Safety and Efficacy of Posterior Juxtascleral Triamcinolone acetonide administration, in addition to Visudyne photoynamic therapy for predominantly Classic Choroidal N...
    Medical condition: Classic or predominantly classic age related macular degeneration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002983-27 Sponsor Protocol Number: PDT05 Start Date*: 2005-11-09
    Sponsor Name:Universitätsklinikum der RWTH Aachen - Ärztlicher Direktor Univ.-Prof. Dr. H. Sass
    Full Title: Prospektive randomisierte Studie zur Untersuchung der Wirksamkeit der Photodynamischen Therapie bei aktinischen Keratosen
    Medical condition: Aktinische Keratose
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003626-32 Sponsor Protocol Number: PDT-PR2 Start Date*: 2018-02-06
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik f. Dermatologie
    Full Title: Photodynamic therapy (pdt) for skin rejuvenation: A pilotstudy evaluating the effectiveness of two modalities of photodynamic therapy in the treatment of photodamaged skin
    Medical condition: Photodamaged skin
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10068388 Actinic elastosis PT
    20.0 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004382-83 Sponsor Protocol Number: ALA-AK-CT009 Start Date*: 2016-06-09
    Sponsor Name:Biofrontera Bioscience GmbH
    Full Title: A randomized, observer-blind, intra-individual phase III study to evaluate the safety and efficacy of BF 200 ALA (Ameluz®) in combination with daylight-PDT (photodynamic therapy) in comparison with...
    Medical condition: Actinic keratosis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-000545-39 Sponsor Protocol Number: DERMAQ-001 Start Date*: 2018-04-30
    Sponsor Name:ASL 1 AVEZZANO-SULMONA-L'AQUILA
    Full Title: A randomized half-side comparative study of Methyl aminolevulinate (MAL, Metvix®) Daylight photodynamic therapy (DL-PDT) with or without pre-treatment with calcitriol (Silkis®) for Actinic Keratosi...
    Medical condition: Actinic Keratosis
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004858 10020648 Hyperkeratoses HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003241-42 Sponsor Protocol Number: ALA-BCC-CT008 Start Date*: 2013-12-23
    Sponsor Name:Biofrontera Bioscience GmbH
    Full Title: A randomized, observer blind, multinational phase III study to evaluate the safety and efficacy of BF-200 ALA (Ameluz®) in comparison to Metvix® in the treatment of non-aggressive basal cell carcin...
    Medical condition: Basal cell carcinoma (BCC)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10004146 Basal cell carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006171-20 Sponsor Protocol Number: Start Date*: 2007-05-22
    Sponsor Name:CHU Angers
    Full Title: Evaluation de l'efficacité de la thérapie photodynamique par Photofrin sur les cholangiocarcinomes non résécables de type III ou IV
    Medical condition: Cholangiocarcinomes de type III ou IV (selon la classification de Bismuth), prouvé histologiquement.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001302-25 Sponsor Protocol Number: 2008-0312-08 Start Date*: 2009-11-05
    Sponsor Name:Lab for pharmaceutical biology [...]
    1. Lab for pharmaceutical biology
    2. Department of Urology
    Full Title: Evaluation of the benefits and effects of hypericin Photodynamic therapy (PDT) in the clinical treatment of superficial bladder carcinoma.
    Medical condition: the study population consists of 10 patients with anatomopathologically proven muscle invasive TCC without metastasis. These patients require a cystoscopy. Before the planned cystoscopy, the bladde...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034942 Photodynamic therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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