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Clinical trials for PFA-100

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    19 result(s) found for: PFA-100. Displaying page 1 of 1.
    EudraCT Number: 2007-004354-90 Sponsor Protocol Number: 270884 Start Date*: 2007-10-03
    Sponsor Name:academisch ziekenhuis Maastricht
    Full Title: Effecten van aspirine op de plaatjesfunctie bij gezonde vrijwillige proefpersonen.
    Medical condition: Aspirin resistance
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004290-26 Sponsor Protocol Number: DC03DIS/4/07 Start Date*: 2008-02-12
    Sponsor Name:J. Uriach y Compañía, S.A
    Full Title: Evaluación del tratamiento con triflusal en pacientes con cardiopatía isquémica estable con no respuesta a AAS
    Medical condition: Profilaxis antiagregante en pacientes con cardiopatía isquémica estable
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000619-16 Sponsor Protocol Number: EC10-060 Start Date*: 2011-06-08
    Sponsor Name:Fundación Investigación Biomedica. Hospital Clinico San Carlos
    Full Title: Identification of the effect of allopurinol treatment on platelets from diabetic patients with stable coronary ischemic disease and aspirin resistance. XUE Study. Estudio cruzado para valorar el...
    Medical condition: Hipótesis: el tratamiento con alopurinol (600 mg/día) en pacientes diabéticos resistentes a aspirina con enfermedad coronaria establecida podría favorecer el efecto antiplaquetario de la aspirina e...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008532-82 Sponsor Protocol Number: ARC1779-010b Start Date*: 2009-02-19
    Sponsor Name:Medical University of Vienna, Dept. of Clinical Pharmacology
    Full Title: A Study of the Pharmacodynamics, Pharmacokinetics, and Safety & Efficacy of ARC1779 Injection in Patients with von Willebrand Disease Type 2B
    Medical condition: von Willebrand Disease type 2B
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004559-36 Sponsor Protocol Number: 1 Start Date*: 2006-03-23
    Sponsor Name:Abteilung für Herz-Thorax-Gefäß Anästhesie & Intensivmedizin (HTG)
    Full Title: Desmopressin in Acquired von Willebrand Syndrome caused by Aortic Valve Stenosis
    Medical condition: Acquired type 2A von Willebrand syndrome is common in patients with severe aortic valve stenosis (AS). It originates from the mechanical obstruction of blood flow and the consecutive proteolysis of...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003265-26 Sponsor Protocol Number: 345 Start Date*: 2017-01-03
    Sponsor Name:Medical University of Vienna
    Full Title: Pharmacokinetic/Pharmacodynamic effects of add-on antiplatelet therapy with parenteral cangrelor as compared to standard dual antiplatelet treatment in patients with ST-elevation myocardial infarct...
    Medical condition: ST-elevation myocardial infarction, cardiac arrest
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2007-004208-11 Sponsor Protocol Number: Kozek200701 Start Date*: 2008-04-28
    Sponsor Name:Medizinische Universität Wien, Univ.-Klinik für Spezielle Anästhesie und Schmerztherapie
    Full Title: Effect of chronic garlic intake on platelet function
    Medical condition: improvement in overall health status by garlic and preoperative setting
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001071-30 Sponsor Protocol Number: V1 Start Date*: 2010-01-21
    Sponsor Name:Medical University Vienna- Dept. of Pediatric Hemostaselology
    Full Title: Aspirin Resistance in Children after Interventional Cardiac Catheterization: The ARC Study
    Medical condition: children after interventional cardiac catheterization.
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001368-22 Sponsor Protocol Number: DG-041-CV-008 Start Date*: 2006-06-01
    Sponsor Name:deCODE genetics ehf.
    Full Title: A randomized, double blind, placebo controlled phase II evaluation of the pharmacokinetics, pharmacodynamics and safety of DG-041 in PAD patients
    Medical condition: Peripheral arterial disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IS (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001232-42 Sponsor Protocol Number: RGHT000270 Start Date*: 2006-06-14
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: The Pharmacogenetics of Aspirin Resistance
    Medical condition: Aspirin resistance: Vascular diseases are common problems and aspirin is used as an anti-platelet drug to prevent thrombosis. However, aspirin's anti-platelet effect may not be uniform in all patie...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000942-11 Sponsor Protocol Number: 140207 Start Date*: 2008-04-30
    Sponsor Name:Medizinische Universität Wien/ Universitätsklinik für Innere Medizin II/ Angiologie und Kardiologie
    Full Title: Vienna-Resistance to Antithrombotic Therapy (REACT)
    Medical condition: Resistance to Aspirin and Clopidogrel
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-002060-34 Sponsor Protocol Number: V1.0 Start Date*: 2008-11-20
    Sponsor Name:Medizinische Universität Wien; Univ.Klin.f.Innere Med. III, Abt.f.Gastroenterologie u. Hepatologie
    Full Title: Impact of Inhibition of Thrombocyte Activation on the course of chronic Hepatitis C
    Medical condition: Chronic Hepatitis C
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2007-006686-32 Sponsor Protocol Number: EC07/90573 Start Date*: 2008-05-22
    Sponsor Name:FUNDACIÓN INVESTIGACIÓN BIOMEDICA DEL HOSPITAL CLINICO SAN CARLOS
    Full Title: Identificación de biomarcadores proteicos asociados a resistencia a la aspirina y a tienopiridinas en pacientes con cardiopatía isquémica establecida. (ESTUDIO BIRAT). Identification of new protei...
    Medical condition: To determine proteins in plasma, leukocytes and platelets associated with aspirin resistance syndrome in stable coronary artery disease patients that may allow us to identify them.It is probably th...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005114-11 Sponsor Protocol Number: FO1 Start Date*: 2011-12-14
    Sponsor Name:AZIENDA USL DI FORLI'
    Full Title: Switching from clopidogrel to prasugrel to protect early invasive treatment in acute coronary syndromes
    Medical condition: Patients with acute coronary syndromes without persistent ST-segment elevation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10051592 Acute coronary syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003807-32 Sponsor Protocol Number: BT200-02 Start Date*: 2020-12-16
    Sponsor Name:Medical University of Vienna
    Full Title: A Phase 2a Multiple Dose “Basket Design” Study Of The Safety, Tolerability, And Pharmacologic Activity Of BT200 In Patients With Hereditary Bleeding Disorders
    Medical condition: - Patients with severe congenital hemophilia A - Patients with mild-moderate hemophilia A - Heterozygous carriers of hemophilia A - Patients with VWD Type 1, e.g. “Vicenza” type - Acquired Von Will...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-005149-18 Sponsor Protocol Number: 033 Start Date*: 2021-04-26
    Sponsor Name:Medical University of Vienna
    Full Title: Preclinical antiplatelet treatment with Cangrelor in patients presenting with ST-Elevation myocardial infarction: a randomized, double-blind, placebo-controlled pilot trial
    Medical condition: ST-Elevation Myocardial Infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003123-35 Sponsor Protocol Number: TRG 10-01 Start Date*: 2011-09-22
    Sponsor Name:University of Oxford
    Full Title: The impact of single versus double dose acetylsalicylic acid on platelet function in patients with type 2 diabetes (the "ASP Study").
    Medical condition: Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2023-000044-34 Sponsor Protocol Number: BT200-VWD2B Start Date*: 2024-08-14
    Sponsor Name:Medical University of Vienna, Department of Clinical Pharmacology
    Full Title: Efficacy and Safety of BT200 (rondoraptivon pegol) in Patients with Type 2B von Willebrand disease
    Medical condition: patients with type 2B Von Willebrand Disease with thrombocytopenia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10047715 Von Willebrand's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004371-19 Sponsor Protocol Number: ARC1779-004 Start Date*: 2007-11-20
    Sponsor Name:Archemix Corp.
    Full Title: A Phase 2 Pilot Study of the Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 Injection in Patients with von Willebrand Factor-Related Platelet Function Disorders
    Medical condition: von Willebrand Factor- related platelet function disorders : thrombotic thrombocytopenic purpura(TTP) in remission, acute TTP, and von Willebrand Disease Type- 2b (vWD-2b).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037563 Purpura thrombopenic thrombotic LLT
    9.1 10047715 Von Willebrand's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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