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Clinical trials for Pack-year

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44337   clinical trials with a EudraCT protocol, of which   7367   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    181 result(s) found for: Pack-year. Displaying page 1 of 10.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2004-004247-22 Sponsor Protocol Number: RES104033 Start Date*: 2005-06-07
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A 28-day, Randomised, Double-Blind, Active Comparator, Controlled Study to Assess the Effects of Rosiglitazone, Inhaled Corticosteroid, Theophylline and Theophylline Plus Inhaled Corticosteroid on ...
    Medical condition: Smokers that are asthmatic
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001093-26 Sponsor Protocol Number: AZALEA Start Date*: 2011-07-20
    Sponsor Name:Imperial College, London
    Full Title: A Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of Oral Azithromycin (500 Mg OD) as a Supplement to Standard Care for Adult Patients with Acute Exacerbations of Asthma
    Medical condition: Asthma (exacerbations of)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-009599-11 Sponsor Protocol Number: 08/0339 Start Date*: 2011-02-15
    Sponsor Name:Joint UCLH/UCL/Royal Free Biomedical Research Unit
    Full Title: Prospective randomised cross over comparison on the physiological response to non-invasive ventilation using either Air O2 or Heliox21
    Medical condition: Respiratory failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002484-99 Sponsor Protocol Number: 2006 Start Date*: 2007-01-10
    Sponsor Name:South Devon Health Care NHS Foundation Trust
    Full Title: The Use of Nebulised Magnesium Sulphate in Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
    Medical condition: We propose a study to examine whether adjuvant magnesium therapy administered via nebuliser is effective in the management of patients with acute exacerbations of COPD. The findings should help to ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000750-31 Sponsor Protocol Number: 10376 Start Date*: 2007-10-16
    Sponsor Name:University Hospitals of Leciester NHS trust
    Full Title: The effect of long term low dose erythromycin on cough frequency in chronic unexplained cough: a randomised, double blind, placebo conrolled, parallel group trial
    Medical condition: Chronic unexplained cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003344-62 Sponsor Protocol Number: mitHDAC Start Date*: 2005-11-15
    Sponsor Name:Imperial College
    Full Title: Effect of theophylline on histone deacetylase activity: enhancement of in-vitro glucocorticoid function in patients with COPD.
    Medical condition: Chronic Obstructive Lung Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001524-38 Sponsor Protocol Number: M/40464/30 Start Date*: 2011-09-23
    Sponsor Name:ALMIRALL, S. A.
    Full Title: EFFICACY AND SAFETY OF ACLIDINIUM BROMIDE/FORMOTEROL FUMARATE FIXED-DOSE COMBINATIONS COMPARED WITH INDIVIDUAL COMPONENTS AND PLACEBO WHEN ADMINISTERED TO PATIENTS WITH STABLE CHRONIC OBSTRUCTIVE P...
    Medical condition: Chronic Obstructive Pulmonary Disorder
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) SK (Completed) HU (Completed) CZ (Completed) ES (Completed) FI (Completed) BE (Completed) DE (Completed) AT (Completed) DK (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002836-25 Sponsor Protocol Number: QGUY/2004/IL 4-13/01 Start Date*: 2004-12-15
    Sponsor Name:Aerovance Inc.
    Full Title: A Phase IIa Study To Investigate The Effects of AER 001on Antigen Challenge In Atopic Asthmatic Subjects Following Repeated Administration.
    Medical condition: Asthma is characterised by an infiltration of the bronchial mucosa with activated T-lymphocytes (T-cells), eosinophils, and to a lessor extent polymorphonuclear leukocytes.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003561-13 Sponsor Protocol Number: cro488 Start Date*: 2006-12-04
    Sponsor Name:imperial college
    Full Title: Reversal of steroid insensitivity in COPD by theophylline
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001090-10 Sponsor Protocol Number: D5892L00002 Start Date*: 2005-08-17
    Sponsor Name:AstraZeneca AB, AstraZeneca Sverige
    Full Title: A randomised, double blind, double dummy, multicentre phase III study comparing the efficacy of budesonide/formoterol (Symbicort® forte Turbuhaler®) and oral prednisolone + formoterol (Oxis® Turbuh...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-015876-86 Sponsor Protocol Number: SCB-004 Start Date*: 2010-04-20
    Sponsor Name:Southampton University Hospitals
    Full Title: An investigation into the mechanisms of action of a combined long acting beta agonist/inhaled corticosteroid (Seretide 500 accuhaler) on the bacterial colonisation, immunology and inflammation of p...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-005857-23 Sponsor Protocol Number: MC/PR/033011/003/05 Start Date*: 2006-05-08
    Sponsor Name:CHIESI
    Full Title: DOUBLE BLIND, DOUBLE DUMMY, RANDOMISED, PARALLEL GROUP, MONOCENTRIC CLINICAL TRIAL ON THE EFFECTS OF CHF 1535 MDI OR SERETIDE DPI ON LUNG HYPERINFLATION AND EXERCISE TOLERANCE IN PATIENTS WITH COPD...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    6.1 10053420 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002952-17 Sponsor Protocol Number: COPDIron Start Date*: 2012-11-12
    Sponsor Name:University of Oxford
    Full Title: Effects of intravenous iron on hypoxic pulmonary responses in COPD
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003833-15 Sponsor Protocol Number: MEU04/118A Start Date*: 2006-11-21
    Sponsor Name:South Manchester University NHS Trust [...]
    1. South Manchester University NHS Trust
    2. Medicines Evaluation Unit
    3. University of Manchester
    Full Title: A randomised parallel group study to investigate the effect of Seretide withdrawal in COPD using non-invasive biomarkers and physiological measurements
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000338-10 Sponsor Protocol Number: 0606 Start Date*: 2006-02-24
    Sponsor Name:NHS Lothian Health Board [...]
    1. NHS Lothian Health Board
    2. Edinburgh Research and Innovation
    Full Title: Can long term nebulised gentamicin reduce the bacterial burden, break the vicious cycle of inflammation and improve quality of life in patients with bronchiectasis?
    Medical condition: Bronchiectasis is respiratory disease with damaged airways. Such patients have frequent bacterial chest infections. The aim of our study is to assess whether nebulised gentamicin 80mg twice daily w...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-000789-11 Sponsor Protocol Number: EL110006 Start Date*: 2005-01-03
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A 12-week, randomised, double-blind, placebo-controlled, parallel-group multicentre study to evaluate the anti-inflammatory activity of GW842470 4mg twice daily on pulmonary hyperinflation in patie...
    Medical condition: Patients with moderate to severe stable chronic obstructive pulmonary disease (COPD) - Stage II or III
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004401-79 Sponsor Protocol Number: 00000000 Start Date*: 2020-04-15
    Sponsor Name:University of Oxford, Clinical Trials and Research Governance
    Full Title: The use of Benralizumab, an interleukin-5 receptor-α monoclonal antibody as treatment of acute exacerbations of airways disease
    Medical condition: Asthma and COPD exacerbations.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10010953 COPD exacerbation LLT
    21.1 100000004855 10015575 Exacerbation of asthma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-001889-81 Sponsor Protocol Number: IMD-10412003-1 Start Date*: 2008-06-24
    Sponsor Name:Institute of Medicinal Molecular Design, Inc.
    Full Title: A Phase IIa, Proof of Concept Study to Evaluate the Reduction in Inflammatory Biomarkers and Assess Airway Function Following Administration of IMD-1041 in Patients with Chronic Obstructive Pulmona...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-000311-15 Sponsor Protocol Number: D9831C00002 Start Date*: 2009-01-29
    Sponsor Name:AstraZeneca AB
    Full Title: A Double-Blind, Placebo-Controlled, Randomised, Parallel Group Phase IIa Study to Evaluate the Histological Changes, Cellularity, Clinical Efficacy and Safety of AZD1981 in Patients with Moderate t...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000046-21 Sponsor Protocol Number: C0524T03 Start Date*: 2004-11-22
    Sponsor Name:Centocor BV
    Full Title: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-ranging Study Evaluating the Efficacy and Safety of CNTO 148 Administered Subcutaneously in Symptomatic Su...
    Medical condition: Severe persistent asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Prematurely Ended) SE (Prematurely Ended) GB (Completed) IT (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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