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Clinical trials for Pain ladder

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    21 result(s) found for: Pain ladder. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-000805-32 Sponsor Protocol Number: 2911 Start Date*: 2007-04-03
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: AN INVESTIGATION INTO THE ROLE OF PARACETAMOL (ACETAMINOPHEN) AT STEP 3 OF THE WHO ANALGESIC LADDER
    Medical condition: The management of cancer pain in patients on step 3 of the WHO analgesic ladder, ie patients on a regular opioids for moderate to severe pain and paracetamol.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001578-26 Sponsor Protocol Number: TVT-Trial Start Date*: 2012-11-07
    Sponsor Name:St Olavs University Hospital [...]
    1. St Olavs University Hospital
    2. The University of Edinburgh
    Full Title: An international, multicentre, open randomised parallel group trial comparing a two step approach to cancer pain relief with the standard three step approach of the WHO analgesic ladder in patients...
    Medical condition: Patients with cancer and cancer pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10058019 Cancer pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002379-89 Sponsor Protocol Number: AGO/2016/007 Start Date*: 2016-09-18
    Sponsor Name:Ghent University Hospital
    Full Title: Treatment of acute locomotoric pain in the geriatric patient: comparison of effectiveness and safety between step 2 (weak opioids) and step 3 (strong opioids) pain relief of the WHO-ladder.
    Medical condition: Acute locomotoric pain in the geriatric patient.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000885-20 Sponsor Protocol Number: Ibondronate Start Date*: 2007-07-20
    Sponsor Name:academic hospital Maastricht
    Full Title: Open label study to establish the efficacy of intravenous loading doses of Ibandronate 6 mg in patients with lung cancer and skeletal metastased experiencing moderate to severe bone pain.
    Medical condition: Patients with lung cancer and malignant disease to bone.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003703-36 Sponsor Protocol Number: BUP-MI-01-04 Start Date*: 2005-04-13
    Sponsor Name:OSPEDALE FATEBENEFRATELLI E OFTALMICO DI MILANO
    Full Title: Open clinical study on the efficacy and tolerability of buprenorfina tds transtec as first line opioid W.H.O. ladder s 3rd step for the medium-long term pain treatment in patients with solid ad...
    Medical condition: Medium-long term treatment of pain in patients with solid advanced tumors
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000550-37 Sponsor Protocol Number: NL52444.058.15 Start Date*: 2015-04-01
    Sponsor Name:LUMC
    Full Title: Effect of Sodium NItroprusside (SNP) on R,S- and S-Ketamine-induced psychotropic side effects, hemodynamic changes and pain relief in healthy volunteers
    Medical condition: Chronic pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005225-30 Sponsor Protocol Number: GWCA0701 Start Date*: 2008-01-17
    Sponsor Name:GW Pharma Ltd.
    Full Title: A double blind, randomized, placebo controlled, parallel group dose range exploration study of Sativex® in relieving pain in patients with advanced cancer, who experience inadequate analgesia durin...
    Medical condition: Pain in patients with advanced cancer, who experience inadequate analgesia during optimized chronic opioid therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) IT (Completed) ES (Completed) FI (Completed) GB (Completed) BE (Completed) DE (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2015-002485-24 Sponsor Protocol Number: CHUBX2014/09 Start Date*: 2015-08-11
    Sponsor Name:CHU de Bordeaux
    Full Title: Effectiveness of oral prednisolone versus partial endodontic treatment on pain reduction in emergency care of acute irreversible pulpitis of mandibular molars: study protocol for a non inferiority ...
    Medical condition: Pulpitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000697-74 Sponsor Protocol Number: ML20115 Start Date*: 2006-08-07
    Sponsor Name:The BONiFIN study group
    Full Title: A phase II, open label study to establish the safety and efficacy of intravenous loading dose of 3 x Bondronat 6 mg in 3 consecutive days in patients with breast cancer and skeletal metastases expe...
    Medical condition: Treatment of pain in breast cancer patients with bone metastases
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002802-48 Sponsor Protocol Number: ML 18107 Start Date*: 2006-09-22
    Sponsor Name:ROCHE
    Full Title: Evaluation of efficacy and safety of i.v. and oral ibandronate in elderly patients with bone metastases from solid tumors. A randomised phase II study
    Medical condition: Treatment of bone metastases in elderly patients with solid tumors
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027484 Metastatic pain LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003278-93 Sponsor Protocol Number: KF5503/34-R331333-PAI-3004 Start Date*: 2007-01-31
    Sponsor Name:Johnson & Johnson Pharamceutical Research & Development, L.L.C.
    Full Title: Randomized, Double-Blind, Active-Control, Parallel Group, 90-Day Safety Study of CG5503 Immediate Release or Oxycodone Immediate Release in Subjects With Chronic Pain from Low Back Pain or Osteoart...
    Medical condition: moderate to severe pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001855-12 Sponsor Protocol Number: BO 18040 Start Date*: 2004-02-16
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Randomized, two arm, placebo controlled study to compare the efficacy of IV loading doses followed by maintenance treatment with IV ibandronic acid versus zoledronic acid in patients with skeletal ...
    Medical condition: Metastatic Bone Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001854-10 Sponsor Protocol Number: BO18039 Start Date*: 2005-02-16
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Randomized, two arm, placebo controlled double dummy study to compare the efficacy of intravenous loading doses followed by maintenance treatment with oral ibandronic acid versus zoledronic acid in...
    Medical condition: Metastatic Bone Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004514-40 Sponsor Protocol Number: KF5503/33-R331333-PAI-3002 Start Date*: 2007-02-14
    Sponsor Name:Johnson & Johnson Pharamceutical Research & Development, L.L.C.
    Full Title: A Randomized, Double-Blind, Active- And Placebo-Controlled, Parallel Group, Multicenter Study To Evaluate The Efficacy And Safety of Multiple Doses of CG5503 Immediate Release Formulation In Subjec...
    Medical condition: Pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014441-93 Sponsor Protocol Number: X-03030-3277 Start Date*: 2010-08-16
    Sponsor Name:MEDA Pharma GmbH & Co. KG
    Full Title: Clinical trial to assess the efficacy of the fixed combination product Tepilta® in the treatment of radiation-induced oesophagitis compared to its active ingredients oxetacaine and antacids, and t...
    Medical condition: Radiation-induced oesophagitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 10022117 - Injury, poisoning and procedural complications 10048899 Radiation oesophagitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-004083-35 Sponsor Protocol Number: 2017-53 Start Date*: 2018-03-28
    Sponsor Name:Assistance Publique Hôpitaux de Marseille
    Full Title: A double-blind, randomized, multicenter study evaluating 200 mg versus 600 mg of Mifepristone on pain in voluntary abortion by drug prior to 7 SA. DoMy Study
    Medical condition: patient of 18 years or more, wishing an abortion with medication before 7 weeks of amenorrhea
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005306-11 Sponsor Protocol Number: SleepRCT_270215 Start Date*: 2016-06-09
    Sponsor Name:St. Olavs Hospital, trondheim University Hospital
    Full Title: Pharmacological treatment of insomnia in palliative care A randomized, double-blind, placebo controlled, parallel-group, multicenter trial investigating the short time effectiveness of zopiclone...
    Medical condition: The overall aim of this clinical trial is to improve the knowledge of the pharmacological treatment of insomnia in patients with advanced cancer who use opioids. Despite the high prevalence of inso...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2011-001739-21 Sponsor Protocol Number: FiDoAp Start Date*: 2012-03-26
    Sponsor Name:ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI - FONDAZIONE "G. PASCALE"
    Full Title: A study of Sativex for pain Relief and appetite stimulation in Patients with advanced malignancy. Phase II
    Medical condition: advanced malignant cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024298-37 Sponsor Protocol Number: ESOT/1/2010 Start Date*: 2011-03-28
    Sponsor Name:Dipartimento Integrato di Oncologia, Ematologia e Patologie dell'Apparato Respiratorio
    Full Title: Early strong opiod treatment in cancer pain -Morphine vs weak opiods
    Medical condition: Tumor Pain, mild-moderate intensity (VAS 3-7)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001660-31 Sponsor Protocol Number: 2586 Start Date*: 2005-08-05
    Sponsor Name:The Royal Marsden Hospital NHS Foundation Trust
    Full Title: A Prospective Randomized Controlled Trial of Morphine versus Oxycodone for Cancer Pain: Genetic Determinants of Response to Opioids.
    Medical condition: 10-30% of cancer patients have an unsuccessful outcome when given oral morphine because of intolerable side effects. Oxycodone is an alternative opioid which is commonly used as a second line opioi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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