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Clinical trials for Pain stimulus

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    36 result(s) found for: Pain stimulus. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2015-002289-21 Sponsor Protocol Number: 48655 Start Date*: 2015-11-26
    Sponsor Name:Academic Medical Center
    Full Title: Parameters in fractional laser assisted delivery of topical anesthetics: role of laser type, laser settings, type of anesthetic and occlusion time
    Medical condition: local anesthesia of the skin prior to minor cutaneous surgical procedures
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004249-16 Sponsor Protocol Number: F02207GE204 Start Date*: 2005-02-02
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: THE EFFECT OF MILNACIPRAN 100MG BID ON SENSITIVITY TO STIMULUS-EVOKED PAIN IN PATIENTS WITH FIBROMYALGIA: A FMRI NEUROIMAGING STUDY
    Medical condition: Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain, widespread tenderness and fatigue. The disorder is well defined in the USA, where the current diagnosis of FMS i...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed) SE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001816-20 Sponsor Protocol Number: 1.1000 Start Date*: 2014-08-28
    Sponsor Name:Academic Medical Center, Amsterdam
    Full Title: Fractional CO2 laser assisted delivery of topical anesthetics: a randomized controlled pilot study
    Medical condition: local anesthesia of the skin prior to minor cutaneous surgical procedures
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001822-24 Sponsor Protocol Number: SM1-PJ-13 Start Date*: 2013-05-28
    Sponsor Name:Professor Jørgen B. Dahl
    Full Title: The effect of different doses (mass) of local anesthetic on duration of adductor canal block in healthy volunteers.
    Medical condition: healthy volunteers ( intended for postoperative pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001752-31 Sponsor Protocol Number: SM1-PJ-14 Start Date*: 2014-06-18
    Sponsor Name:Professor Jørgen B. Dahl
    Full Title: The effect of different doses (mass) of local anesthetic on duration of adductor canal block in healthy volunteers - part 2
    Medical condition: healthy volunteers ( intended for postoperative pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-004812-73 Sponsor Protocol Number: BP18-1-501 Start Date*: 2022-05-16
    Sponsor Name:Leiden University
    Full Title: The influence of pharmacological conditioning with S-ketamine on pain sensitivity in patients with Fibromyalgia Syndrome
    Medical condition: Fibromyalgia Syndrome
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004738-15 Sponsor Protocol Number: ADO WAD No-of-1 Start Date*: 2005-02-03
    Sponsor Name:Karolinska University Hospital, Huddinge
    Full Title: Intermittent intravenous adenosine with prolonged pain in the back of the neck with allodynia/dysaesthesia.
    Medical condition: Prolonged pain in the neck caused by a whiplash trauma or another muscle injury.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000557-35 Sponsor Protocol Number: NW-1029/001/II/2003 Start Date*: 2005-06-09
    Sponsor Name:Newron Pharmaceuticals SpA
    Full Title: A phase II, multi centre, pilot, randomised, ascending dose, double -blind, placebo controlled, dose titration study to determine the safety, maximum tolerated dose and preliminary evidence of effi...
    Medical condition: Neuropathic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-023175-26 Sponsor Protocol Number: P_TPT_2010 Start Date*: 2011-01-14
    Sponsor Name:Leiden University Medical Center
    Full Title: Influence of Tapentadol on endogenous modulation of pain in chronic neuropathic pain patients and healthy volunteers
    Medical condition: Chronic pain patients/ mhealthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    12.1 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012094-35 Sponsor Protocol Number: D5090C00018 Start Date*: 2009-08-11
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase IIa randomised, double-blind, placebo controlled, parallel group, multicentre study evaluating the efficacy, safety, tolerability and pharmacokinetics of AZD1386 after 3 weeks of treatment...
    Medical condition: Patients with Posttraumatic Neuralgia (PTN) and Postherpetic Neuralgia (PHN) Intended Indication is Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029223 Neuralgia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) FR (Completed) DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000058-73 Sponsor Protocol Number: LIPS Start Date*: 2012-09-14
    Sponsor Name:University of Liverpool [...]
    1. University of Liverpool
    2. Walton Centre NHS Foundation Trust
    Full Title: A multi-centre (UK) double-blind randomised parallel group placebo controlled trial to evaluate the efficacy, safety, and tolerability of Intravenous Immunoglobulin (IVIg) 0.5g/kg plus standard tre...
    Medical condition: Complex Regional Pain Syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002159-41 Sponsor Protocol Number: Mo_top_Sb_100505 Start Date*: 2005-10-03
    Sponsor Name:Department of Anaesthesia & General Intensive Care Medicine
    Full Title: Investigation of the antihyperalgesic effect of topical buprenorphine in an UV-B induced inflammatory skin pain model in healthy volunteers
    Medical condition: Volunteer study with healthy volunteers using the UV-B-model as model of hyperalgesia.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008475-34 Sponsor Protocol Number: Remi-Sunburn-1 Start Date*: 2009-02-25
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-011599-31 Sponsor Protocol Number: RemiAnes1 Start Date*: 2009-06-26
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high-dose remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP ist studied
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003208-22 Sponsor Protocol Number: CaPsaPPP-01 Start Date*: 2015-11-06
    Sponsor Name:Wilhelminen hospital
    Full Title: Does a two-day pretreatment with capsaicin reduce postoperative hyperalgesia and pain in surgical patients A prospective, randomized, double-blind, placebo-controlled, parallel group, single-cente...
    Medical condition: postoperative secondary mechanical hyperalgesia and postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-004549-14 Sponsor Protocol Number: Remi-Capsaicin-1 Start Date*: 2008-02-15
    Sponsor Name:Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna [...]
    1. Department of Anaesthesie, General Intensive Care and Pain Therapy, Medical University of Vienna
    2.
    Full Title: A novel role for remifentanil: the reversal of established capsaicin-induced hyperalgesia.
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004426-93 Sponsor Protocol Number: lido_caps_sb_200509 Start Date*: 2005-10-28
    Sponsor Name:Department of Anaesthesia and General Intensive Care Medicine
    Full Title: Investigation of antihyperalgesic effect...
    Medical condition: volunteer study with healthy volunteers using the intradermal capsaicin injection and UV-B sunburn as models of hyperalgesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-003605-13 Sponsor Protocol Number: Remi-Capsaicin-2 Start Date*: 2008-12-03
    Sponsor Name:Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of remifentanil on the reversal of established capsaicin-induced hyperalgesia in human volunteers
    Medical condition: This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000908-15 Sponsor Protocol Number: IMI2-PainCare-BioPain-RCT4 Start Date*: 2019-09-24
    Sponsor Name:Aarhus University
    Full Title: A randomized, double-blind, placebo-controlled, cross-over trial in healthy subjects to investigate the effects of lacosamide, pregabalin and tapentadol on biomarkers of pain processing observed by...
    Medical condition: Healthy volunteers (intended indication: pain)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2012-000402-30 Sponsor Protocol Number: ESTEVE-SIGM-205 Start Date*: 2012-06-18
    Sponsor Name:Laboratorios del Dr. Esteve. S.A
    Full Title: An exploratory, randomized, double blind, placebo controlled, parallel groups Phase II clinical trial to evaluate the efficacy and safety of E-52862 (400 mg) by oral route, in patients with post-su...
    Medical condition: Post-surgical neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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