- Trials with a EudraCT protocol (30)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (2)
30 result(s) found for: Parasite.
Displaying page 1 of 2.
EudraCT Number: 2016-001718-31 | Sponsor Protocol Number: VAC063 | Start Date*: 2016-08-24 |
Sponsor Name:University of Oxford, CTRG | ||
Full Title: A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium falciparum malaria vaccine candidate RH5.1/AS01 | ||
Medical condition: Plasmodium falciparum malaria | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2016-004905-15 | Sponsor Protocol Number: DNDi-FEX-12-CH | Start Date*: 2017-09-13 |
Sponsor Name:Drugs for Neglected Diseases initiative (DNDi) | ||
Full Title: Phase 2 Randomized, Multicenter, Double-blinded Safety and Efficacy Study to Evaluate Oral Fexinidazole Dosing Regimens for the Treatment of Adult Patients with Chronic Indeterminate Chagas Disease | ||
Medical condition: Chagas disease (CD) is a disease caused by Trypanosoma cruzi, ranking among the world’s most neglected diseases. There is significant associated morbidity and mortality, particularly in chronic ph... | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Completed) | ||
Trial results: View results |
EudraCT Number: 2017-002723-16 | Sponsor Protocol Number: PREMIVER | Start Date*: 2018-04-20 |
Sponsor Name:Universitaetsklinikum Tuebingen | ||
Full Title: Evaluation of the potential anti-malarial effect of ivermectin: a controlled human malaria infection trial | ||
Medical condition: In spite of remarkable progress over the last 15 years, malaria continues to be a major public health problem in the developing world with an estimated 214 million cases and 438.000 deaths in 2014.... | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: DE (Completed) | ||
Trial results: View results |
EudraCT Number: 2014-005510-34 | Sponsor Protocol Number: MMV_DSM265_14_01 | Start Date*: 2015-09-30 | |||||||||||
Sponsor Name:Medicines for Malaria Venture | |||||||||||||
Full Title: Evaluation of the prophylactic antimalarial activity of a single dose of DSM265 in non-immune healthy adult volunteers by controlled human malaria infection with PfSPZ Challenge | |||||||||||||
Medical condition: Healthy volunteers; controlled human malaria infection with PfSPZ | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-012591-27 | Sponsor Protocol Number: VAC037 | Start Date*: 2009-11-16 |
Sponsor Name:University of Oxford | ||
Full Title: A phase I/IIa study to assess the safety and immunogenicity of new malaria vaccine candidates AdCh63 MSP1 alone and with MVA MSP1 | ||
Medical condition: Plasmodium Falciparum Malaria | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2012-002645-38 | Sponsor Protocol Number: BIOMARCHA | Start Date*: 2012-09-04 |
Sponsor Name:CRESIB-Barcelona Centre for International Health Research | ||
Full Title: Evolution of serologic biomarkers and diastolic function and segmentary contractility determined by echocardiography after treatment in Chagas diseases | ||
Medical condition: The study will be held in 63 patients with chronic Chagas Disease and 63 healthy people | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2007-005389-11 | Sponsor Protocol Number: VAC035 | Start Date*: 2009-05-07 | |||||||||||
Sponsor Name:University of Oxford | |||||||||||||
Full Title: A Phase I/IIa Study of the Safety, Immunogenicity and Parasite Growth Inhibitory Activity of AMA1-C1/Alhydrogel® + CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium falciparum Malaria | |||||||||||||
Medical condition: Plasmodium falciparum malaria | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-000643-27 | Sponsor Protocol Number: VAC071 | Start Date*: 2019-09-23 | |||||||||||
Sponsor Name:University of Oxford / Clinical Trials and Research Governance | |||||||||||||
Full Title: A Phase IIa challenge study to assess efficacy of the Plasmodium vivax malaria vaccine candidates ChAd63 PvDBP and MVA PvDBP in healthy adults living in the UK | |||||||||||||
Medical condition: Plasmodium vivax malaria | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-004906-14 | Sponsor Protocol Number: A0661201 | Start Date*: 2015-04-07 |
Sponsor Name:Pfizer Inc | ||
Full Title: An Open Label, Non-Comparative Study To Evaluate Parasitological Clearance Rates and Pharmacokinetics of Azithromycin and Chloroquine Following Administration of a Fixed Dose Combination of Azithro... | ||
Medical condition: Asymptomatic Parasitemia | ||
Disease: | ||
Population Age: Adolescents, Under 18, Adults | Gender: Female | |
Trial protocol: Outside EU/EEA | ||
Trial results: View results |
EudraCT Number: 2011-005477-24 | Sponsor Protocol Number: VAC045 | Start Date*: 2012-02-28 |
Sponsor Name:University of Oxford | ||
Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Protective Efficacy of Two Prime-boost Malaria Vaccine Candidates: ChAd63 and MVA encoding ME-TRAP and the same Viral Vectors encoding CS | ||
Medical condition: Plasmodium falciparum infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2022-004143-27 | Sponsor Protocol Number: STRONG-FIX | Start Date*: 2023-09-14 | |||||||||||
Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR) | |||||||||||||
Full Title: Randomized non-inferiority clinical trial to evaluate the efficacy of a single fixed dose of 18 mg ivermectin for the treatment of uncomplicated strongyloidiasis | |||||||||||||
Medical condition: Strongyloidiasis is caused by a parasite that is globally distributed in tropical and sub-tropical areas. Most patients with strongyloidiasis are asymptomatic or have mild symptoms with gastrointes... | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-002022-41 | Sponsor Protocol Number: CHAGAS-EVOL I | Start Date*: 2011-10-13 | |||||||||||
Sponsor Name:Fundación para la Investigación Biomédica del Hospital Ramón y Cajal | |||||||||||||
Full Title: Assessment of Therapeutic Response to Benznidazole in patients with Chronic Chagas Disease by Measuring Plasma Parasite Load and the Specific Immune Response against Trypanosoma cruzi. A Randomized... | |||||||||||||
Medical condition: Chagas disease | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-001333-14 | Sponsor Protocol Number: CCOA566B2303 | Start Date*: 2012-03-09 | |||||||||||
Sponsor Name:Novartis Pharma AG | |||||||||||||
Full Title: A randomized, investigator-blinded, multicenter, parallel group study to compare efficacy, safety and tolerability of Coartem® dispersible tablet formulation vs. Coartem® 6-dose crushed tablet in t... | |||||||||||||
Medical condition: This study will evaluate the safety and efficacy of artemether-lumefantrine against uncomplicated malaria caused by Plasmodium falciparum in children. | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: Outside EU/EEA | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-005852-33 | Sponsor Protocol Number: CCOA566B2306 | Start Date*: 2016-04-11 | |||||||||||
Sponsor Name:Novartis Pharma AG | |||||||||||||
Full Title: An open-label, single-arm study to evaluate the efficacy, safety and PK of artemether-lumefantrine Dispersible Tablet in the treatment of acute uncomplicated Plasmodium falciparum malaria in infant... | |||||||||||||
Medical condition: The purpose of the study is to obtain efficacy, safety and pharmacokinetic (PK) data following treatment with artemether-lumefantrine dispersible tablet in infants < 5 kg of body weight (BW) with u... | |||||||||||||
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Population Age: Newborns, Infants and toddlers, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: Outside EU/EEA | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-001075-23 | Sponsor Protocol Number: VAC066 | Start Date*: 2018-09-05 |
Sponsor Name:University of Oxford, CTRG | ||
Full Title: A Phase I/IIa Sporozoite Challenge Study to assess the safety, immunogenicity and protective efficacy of intravenous boosting with malaria vaccine candidates ChAd63 and MVA encoding ME-TRAP | ||
Medical condition: Plasmodium falciparum infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2016-003789-21 | Sponsor Protocol Number: MULTBENZ | Start Date*: 2017-01-11 | |||||||||||
Sponsor Name:Fundación Hospital Universitari Vall d'Hebron - Institut de Recerca | |||||||||||||
Full Title: Phase II trial for assessing different benznidazol regimens in the treatment of Chagas disease in adult patients on chronic phase . BERINECE project | |||||||||||||
Medical condition: Chagas Disease on chronic phase | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-001049-28 | Sponsor Protocol Number: VAC067 | Start Date*: 2017-05-26 |
Sponsor Name:University of Oxford, CTRG | ||
Full Title: A Phase I/II Study to assess the safety, immunogenicity and protective efficacy of novel malaria vaccine candidates ChAdOx1 LS2 and MVA LS2 in healthy UK adults | ||
Medical condition: Plasmodium falciparum infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2010-018341-56 | Sponsor Protocol Number: VAC039 | Start Date*: 2010-05-07 |
Sponsor Name:University of Oxford | ||
Full Title: A phase I/IIa sporozoite challenge study to assess the safety, immunogenicity and protective efficacy of new malaria vaccine candidates; AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP... | ||
Medical condition: Malaria (plasmodium falciparum) | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-001226-42 | Sponsor Protocol Number: MEBENDAZOLGAI3002 | Start Date*: 2015-04-09 | |||||||||||
Sponsor Name:Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | |||||||||||||
Full Title: An Open-Label, Single-Dose Study to Assess the Safety of 500-mg Mebendazole Chewable Formulation in Children 2 to 10 Years of Age, Inclusive | |||||||||||||
Medical condition: Soil-transmitted helminth (STH) infections | |||||||||||||
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Population Age: Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: Outside EU/EEA | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-002872-14 | Sponsor Protocol Number: VAC079 | Start Date*: 2019-11-12 | |||||||||||
Sponsor Name:University of Oxford / Clinical Trials and Research Governance | |||||||||||||
Full Title: A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium vivax malaria vaccine candidate PvDBPII in Matrix M1 in healthy adults living in the UK | |||||||||||||
Medical condition: Plasmodium vivax malaria | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: View results |
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