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Clinical trials for Perioperative medicine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    18 result(s) found for: Perioperative medicine. Displaying page 1 of 1.
    EudraCT Number: 2012-004082-41 Sponsor Protocol Number: DELIcu Start Date*: 2013-03-06
    Sponsor Name:Dekan of Faculty of Medicine of Goethe-University Frankfurt
    Full Title: Monocenter, double blind, randomised, placebo controlled study t evaluate Physostigmin for the Treatment of delirium in perioperative intensive care medicine
    Medical condition: patients with delirium in perioperative intensive care medicine
    Disease: Version SOC Term Classification Code Term Level
    17.1 10037175 - Psychiatric disorders 10012221 Deliria (incl confusion) HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016043-19 Sponsor Protocol Number: HIPSTER Start Date*: 2010-04-12
    Sponsor Name:Charité – University Medicine Berlin
    Full Title: Impact of a balanced infusion solution compound of 50% cristalloid and 50% colloid versus a unbalanced infusion solution of 100% cristalloid within a goal-directed hemodynamic protocol on acid-base...
    Medical condition: Patients undergoing elective hip replacement surgery will be divided into two groups. In one group an intravenous application of Ringer Baxter Infusionsloesung, in the other group a parallel intra...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-003537-15 Sponsor Protocol Number: TXA2018 Start Date*: 2019-02-18
    Sponsor Name:Medical University Vienna
    Full Title: Different dosing of Tranexamic Acid in patients undergoing elective total hip or knee arthroplasty. A randomized, controlled, double-blinded clinical trial.
    Medical condition: Blood loss in patients undergoing elective total hip or knee arthroplasty.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10053220 Hip injury LLT
    20.1 100000004863 10049032 Knee injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004582-14 Sponsor Protocol Number: XENOMICRO Start Date*: 2014-01-28
    Sponsor Name:Department of Anesthesiology and Perioperative Medicine
    Full Title: Haemodynamic effects of xenon or sevoflurane anesthesia on microcirculation
    Medical condition: Patients with ASA III classification (left ventricular failure) undergoing implantation of a defibrillator.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001425-48 Sponsor Protocol Number: BLUEBERRY Start Date*: 2021-07-07
    Sponsor Name:Division of Anaesthesiology - Department of Acute Medicine - Geneva Children's Hospital, University Hospitals of Geneva
    Full Title: Dexamethasone and postoperative bleeding following tonsillectomy in children
    Medical condition: Tonsillectomy/tonsillotomy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001214-10 Sponsor Protocol Number: AAUH-01-2015 Start Date*: 2015-06-02
    Sponsor Name:Aalborg universitets hospital [...]
    1. Aalborg universitets hospital
    2. Ortopædkirurgisk forskningsenhed, Aalborg universitetshospital
    Full Title: Analgetic effect of perioperative klorzoxazon at total hip or knee arthroplasty
    Medical condition: Perioperative pain after incertion of hip or knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10023469 Knee arthroplasty PT
    18.0 10042613 - Surgical and medical procedures 10020096 Hip arthroplasty PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-001846-24 Sponsor Protocol Number: 1 Start Date*: 2016-06-29
    Sponsor Name:Antwerp University Hospital
    Full Title: Metabolism of Isotonic versus Hypotonic Maintenance Solutions in fasting healthy Adults (MIHMoSA), a Single-Blind Randomized Crossover Trial
    Medical condition: Healthy adult volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-003664-28 Sponsor Protocol Number: Cp50PropofolPregabalin Start Date*: 2022-07-18
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, Critical Care and Pain Medicine
    Full Title: The Effect of Pregabalin on the Cp50 of Propofol
    Medical condition: This study aims to investigate the effect of a clinically used dose of Pregabalin on the Cp50 of propofol to provide more information to clinicians using this adjunctive drug in the perioperative s...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005457-31 Sponsor Protocol Number: ANES003 Start Date*: 2012-04-16
    Sponsor Name:UZBrussel Department of Anesthesiology and Perioperative Medicine; Acute and Chronic Pain Therapy
    Full Title: The effect of the combination of midazolam with Ropivacaine in loco-regional anesthesia.
    Medical condition: All patients scheduled for limb surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000726-63 Sponsor Protocol Number: PHPT2018 Start Date*: 2018-06-14
    Sponsor Name:Department of Clinical Physiology and Nuclear Medicine, Herlev and Gentofte Hospital
    Full Title: Pre- and Postoperative Imaging and Monitoring of Patients with Primary Hyperparathyroidism: Preoperative imaging in primary hyperparathyroidism using dual-isotope subtraction scintigraphy (SPECT/C...
    Medical condition: Primary hyperparathyroidism
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10036693 Primary hyperparathyroidism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002385-39 Sponsor Protocol Number: HSPOD Start Date*: 2018-12-06
    Sponsor Name:County Council of Västerbotten
    Full Title: Infusion of hypertonic solutions: A risk factor for delirium after cardiac surgery? A randomised double blinded controlled trial.
    Medical condition: The present investigation aims to investigate the risk of developing delirium after cardiac surgery, when using a hyperosmolar priming solution for cardiopulmonary bypass
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-000402-30 Sponsor Protocol Number: SO_SH_01_2019 Start Date*: 2019-04-10
    Sponsor Name:Viktoria Lindberg-Larsen
    Full Title: The effect of perioperative dexamethasone administration on postoperative pain in patients undergoing periacetabular osteotomy: A randomised double-blind, placebo-controlled trial
    Medical condition: Dysplasia of the hip
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10063175 Hip dysplasia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003682-19 Sponsor Protocol Number: OxyPir1 Start Date*: 2020-12-18
    Sponsor Name:UZ Brussel
    Full Title: Post-operative patient controlled intravenous oxyco-done vs patient controlled intrav nous piritramide. A randomized controlled trial.
    Medical condition: To determine whether oxycodone gives better postoperative pain relief (using VAS scores) than IV piritramide in abdominal and gynecological surgery.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004707-38 Sponsor Protocol Number: CCR 3065 Start Date*: 2005-04-08
    Sponsor Name:Royal Marsden NHS Trust
    Full Title: A multicentre randomised phase II clinical trial comparing oxaliplatin (Eloxatin), capecitabine (Xeloda) and pre-operative radiotherapy with or without cetuximab followed by total mesorectal excisi...
    Medical condition: High risk operable rectal adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10038038 Rectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) ES (Ongoing) SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023839-42 Sponsor Protocol Number: H8O-CY-O027 Start Date*: 2011-04-29
    Sponsor Name:General University Hospital in Prague
    Full Title: EXEnatide in patients undergoing Coronary artery bypass grafting for improved glUcose conTrol and hemodynamIc ValuEs
    Medical condition: Patients with elective coronary artery bypass grafting with LV systolic dysfunction (EF LV ≤ 50%)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    14.1 10014698 - Endocrine disorders 10012602 Diabetes mellitus (incl subtypes) HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002670-39 Sponsor Protocol Number: PROXI2017 Start Date*: 2018-02-01
    Sponsor Name:Bispebjerg Hospital
    Full Title: Hyperoxia and antioxidant intervention during major non-cardiac surgery and risk of cerebral and cardiovascular complications, a blinded 2x2 factorial randomized clinical trial
    Medical condition: Patients undergoing major non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10007654 Cardiovascular injuries HLT
    20.0 10042613 - Surgical and medical procedures 10064939 Cardiovascular event prophylaxis PT
    20.1 100000004849 10007648 Cardiovascular disease, unspecified LLT
    20.0 100000004849 10032964 Other symptoms involving cardiovascular system LLT
    20.0 100000004869 10078955 Cardiovascular risk LLT
    20.0 10042613 - Surgical and medical procedures 10052616 Intraoperative care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004602-86 Sponsor Protocol Number: Start Date*: 2005-11-21
    Sponsor Name:Medical University of Vienna
    Full Title: A comparison of crystalloids vs. colloids for intraoperative goal-directed fluid management
    Medical condition: Fluid optimization has been considered as major contributor to improved oxygen delivery, and thus improved outcome in patients. Hypovolemia has been associated with significant increases in morbid...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-003238-15 Sponsor Protocol Number: Schaefers0711 Start Date*: 2012-12-12
    Sponsor Name:KKRN Katholisches Klinikum Ruhrgebiet Nord GmbH
    Full Title: Quality of analgesia and side effect incidence and severity during postoperative pain management with Palexia® compared to Targin®
    Medical condition: Management of postoperative pain in trauma surgery patients (adults) requiring postoperative opiates for the management of postoperative pain.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
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