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Clinical trials for Placebo comparator

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,804 result(s) found for: Placebo comparator. Displaying page 1 of 91.
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    EudraCT Number: 2019-000796-16 Sponsor Protocol Number: 000014/BT Start Date*: 2020-03-03
    Sponsor Name:Bone Therapeutics SA
    Full Title: A Multicenter, Randomized, Double-blind, Placebo- and Active-Controlled Phase III Study on the Safety and Efficacy of a Single Intra-articular Administration of JTA-004 in Symptomatic Knee Osteoart...
    Medical condition: Symptomatic osteoarthritis of the knee with Kellgren-Lawrence grade II and III
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) GB (GB - no longer in EU/EEA) PL (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2006-000905-41 Sponsor Protocol Number: none Start Date*: 2006-06-07
    Sponsor Name:ao. Univ. Prof. Dr. Elisabeth Aberer
    Full Title: Offene, monozentrische, randomisierte, placebo-kontrollierte, einfach blinde und Observer-blinde klinische Studie bei PatientInnen mit Raynaud Syndrom mit / ohne progressiver systemischer Skleroder...
    Medical condition: Raynaud syndrome with / without systemic sclerosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004803-30 Sponsor Protocol Number: R2060 Start Date*: 2017-03-31
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A multi-centre, randomised, placebo and active-controlled, double-blind, cross-over, phase IIa proof-of-concept trial to investigate the efficacy and safety of AX-8 Tablets 5 mg in patients with ch...
    Medical condition: Chronic refractory cough and associated upper airway symptoms.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004169-41 Sponsor Protocol Number: CQAB149B2329 Start Date*: 2006-01-19
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 52-week treatment, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety and tolerability of indacaterol (200 & 400 µg o.d) in patients wi...
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002876-15 Sponsor Protocol Number: MCMK0112 Start Date*: 2012-11-23
    Sponsor Name:Cassella-med GmbH & Co KG
    Full Title: A randomised, multi-centre, parallel group, double-blind, placebo- and active-controlled clinical study to assess the efficacy and safety of Octenidine lozenges in the treatment of acute sore throat.
    Medical condition: Acute pharyngitis
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003526-25 Sponsor Protocol Number: IC51-308 Start Date*: 2005-10-26
    Sponsor Name:Intercell AG
    Full Title: Safety and immunogenicity of concomitant vaccination with IC51 and Havrix 1440 in healthy subjects. A single-blind randomised, controlled phase 3 study.
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-003144-36 Sponsor Protocol Number: NAC.TEP16 Start Date*: 2020-11-18
    Sponsor Name:Radboud University Medical Centre
    Full Title: Pilot study: postoperative pain reduction by pre emptive N-Acetylcysteine
    Medical condition: postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-003660-38 Sponsor Protocol Number: 2005/3 Start Date*: 2005-10-31
    Sponsor Name:Medizinische Universitätsklinik
    Full Title: Effects of urapidil and doxazosin on heart rate
    Medical condition: Healthy males
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004098-17 Sponsor Protocol Number: 35195 Start Date*: 2009-03-31
    Sponsor Name:East Tallinn Central Hospital
    Full Title: Double-Blind, Randomized, Placebo -Controlled Study to Evaluate the Efficacy of Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in th...
    Medical condition: Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in the Treatment of Postoperative Pain in Patients Undergoing Gynaecologic Laparoscop...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: EE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002349-30 Sponsor Protocol Number: cod2017 Start Date*: 2017-09-12
    Sponsor Name:TARGID, KU Leuven
    Full Title: Effect of codeine on pharyngeal and esophageal motility in healthy subjects: a double-blind, placebo-controlled, randomized, cross-over study
    Medical condition: we will investigate the effect of codeine on motility in the pharynx and esophagus in healthy subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-004903-22 Sponsor Protocol Number: TOC110977 Start Date*: 2016-12-12
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A randomized, double-blind, multicenter, superiority Phase III study to assess the safety and efficacy of Topical Retapamulin Ointment 1%, applied twice daily versus Placebo Ointment in Adults and ...
    Medical condition: Secondarily-infected traumatic lesions (SITL), excluding those with abscesses.
    Disease:
    Population Age: Adolescents, Under 18, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-004168-21 Sponsor Protocol Number: CQAB149B2328 Start Date*: 2006-01-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 52-week treatment, multicenter, randomized, double-blind, double dummy, placebo-controlled, parallel-group study to assess the efficacy, safety and tolerability of indacaterol (200 & 400 µg o.d.)...
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006942-33 Sponsor Protocol Number: 13/06/IBL/TP3 Start Date*: 2007-03-30
    Sponsor Name:Zentiva a.s.
    Full Title: Randomised, Double Dummy, Placebo Controlled, Multicentre, Parallel-Group, Single Dose Study to Compare the Analgesic Efficacy and Safety of IBALGIN Extra Fast /ibuprofen lysin/ to conventional Ibu...
    Medical condition: subject is indicated for outpatient surgical removal of one or more third molars, at least one of which is impacted in bone
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028819 Nausea vomiting and diarrhea LLT
    9.1 10019211 Headache LLT
    9.1 10017822 Gastric ulcer LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-000693-57 Sponsor Protocol Number: Ledin03 Start Date*: 2011-11-29
    Sponsor Name:Håkan Ledin (investigator initiated trial)
    Full Title: A Randomized, Placebo-controlled, Double-blind, Two-center Study with Denosumab in Subjects Undergoing Elective Total Knee Replacement Surgery
    Medical condition: Patients with idiopathic osteoarthritis of the knee, scheduled for a cemented total knee prosthesis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004836-31 Sponsor Protocol Number: Tav01-13 Start Date*: 2014-04-07
    Sponsor Name:Montavit Ges.m.b.H.
    Full Title: Double-blind, randomised, placebo-controlled study evaluating the efficacy and safety of Tavipec capsules in acute Bronchitis A prsopective, multi-centre, parallel group, interventional clinical ph...
    Medical condition: acute bronchitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2023-000007-39 Sponsor Protocol Number: N/A. Start Date*: 2023-03-23
    Sponsor Name:Aarhus University Hospital, Department of Endocrinology and Internal Medicine
    Full Title: Bisphosphonate vs. Placebo Prior to Parathyroidectomy in Primary Hyperparathyroidisme: A Randomized, blinded Placebo-controlled Trial
    Medical condition: Osteopenia i.e. bone mineral density T-score < -1 in patients with primary hyperparathyroidism
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10005991 Bone mass decreased LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003425-42 Sponsor Protocol Number: PS0009 Start Date*: 2018-03-16
    Sponsor Name:UCB Biopharma SPRL
    Full Title: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- and Active Comparator-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects with Moderate ...
    Medical condition: Moderate to Severe Chronic Plaque Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10071117 Plaque psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) HU (Completed) BE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002046-16 Sponsor Protocol Number: MARS_2020 Start Date*: 2020-11-04
    Sponsor Name:Fakultní nemocnice Brno
    Full Title: A Randomised, double-blinded, placebo-controlled, multicenter study of efficacy, safety and side effects of highly diluted atropine collyrium in slowing the progression of myopia (shortsightedness)...
    Medical condition: Myopia in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-012855-90 Sponsor Protocol Number: BEDJ002 Start Date*: 2009-07-29
    Sponsor Name:Jelfa SA
    Full Title: Randomised, placebo-controlled, double-blind, parallel-group, comparative study of two topical products for the treatment of psoriasis
    Medical condition: mild to moderate plaque psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001511-70 Sponsor Protocol Number: 44313 Start Date*: 2015-08-05
    Sponsor Name:Maastricht University Medical Center
    Full Title: Efficacy, safety and tolerability of lacosamide in patients with gain-of-function Nav1.7 mutations related small fiber neuropathy: a randomized, double-blind, placebo controlled, crossover trial
    Medical condition: SCN9A mutation related small fiber neuropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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