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Clinical trials for Preconditioning

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    17 result(s) found for: Preconditioning. Displaying page 1 of 1.
    EudraCT Number: 2007-006233-14 Sponsor Protocol Number: 2007-006233-14 Start Date*: 2008-01-03
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – Helium induced Early and Late Preconditioning (HELP) in human endothelium
    Medical condition: healthy volunteers helium induced organ protection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004746-28 Sponsor Protocol Number: POR-TAP-16-007 Start Date*: 2017-10-05
    Sponsor Name:UNIVERSITÀ CATTOLICA DEL SACRO CUORE- POLICLINICO A. GEMELLI
    Full Title: Ticagrelor And PrEconditioning in patients with stable coronaRy artery diSease: a randomized pilot trial (TAPER-S trial)
    Medical condition: Patients with multivessel coronary artery disease requiring staged, ischemia-guided PCI
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10074572 Multiple vessel coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002288-32 Sponsor Protocol Number: ESR-14-10310 Start Date*: 2016-11-14
    Sponsor Name:Greek Corporation of Invasive Cardiology
    Full Title: Ticagrelor Potentiation of Remote Ischemic Preconditioning: The Ticagrelor in Remote Ischemic Preconditioning (TRIP) study
    Medical condition: Patient with NSTE-ACS referred for coronary angiography
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003556-23 Sponsor Protocol Number: PROMIT Start Date*: 2019-10-15
    Sponsor Name:University Hospital of the Friedrich-Alexander University Erlangen-Nürnberg
    Full Title: A Phase 2, single arm study on dacarbazine (DTIC) followed by immunotherapy re-challenge in unresectable or metastatic melanoma with primary resistance to PD-1/PD-L1 or PD-1 + CTLA4 Blockade Pre...
    Medical condition: Melanoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10027481 Metastatic melanoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-004398-76 Sponsor Protocol Number: gjnh/mccormick/01 Start Date*: 2006-03-22
    Sponsor Name:Golden Jubilee National Hospital
    Full Title: A comparison of Myocardial Protection Using Preconditioning with Sevoflurane Against High Thoracic Epidural Analgesia for CABG Surgery
    Medical condition: Ischaemic heart disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-000992-12 Sponsor Protocol Number: HIPP-CABG Start Date*: 2008-03-27
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – A clinical study to investigate Helium induced Pre- and Postconditioning in patients undergoing coronary artery bypass surgery (HIPP-CABG).
    Medical condition: patients undergoing coronary artery bypass surgery, helium induced pre- and postconditioning
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004723-35 Sponsor Protocol Number: SEVO-DIP Start Date*: 2005-01-27
    Sponsor Name:OSPEDALE S. RAFFAELE DI MILANO
    Full Title: PRECONDITIONING EFFECT OF INALATORY ANESTHETICS
    Medical condition: SEVOFLURANE USED AS ANESTETIC IN ORDER TO OBTAIN A MYOCARDIAL PROTECTION
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001690-62 Sponsor Protocol Number: HE2016 Start Date*: 2014-09-16
    Sponsor Name:University of Birmingham
    Full Title: A randomised phase II clinical trial of conditioning cyclophosphamide and chemoembolisation with or without vaccination with dendritic cells pulsed with HepG2 lysate ex vivo in patients with Hepato...
    Medical condition: Hepatocellular carcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10049010 Carcinoma hepatocellular LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-005445-16 Sponsor Protocol Number: NL74623.078.20 Start Date*: 2021-02-23
    Sponsor Name:Erasmus MC, University Medical Center Rotterdam
    Full Title: Fasting before live kidney donation, effect on donor wellbeing and postoperative recovery
    Medical condition: Preoperative fasting in combination with a low-dose laxative and postoperative recovery and complications in living kidney donors
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001922-24 Sponsor Protocol Number: 120541 Start Date*: 2013-07-12
    Sponsor Name:University College London (UCL)
    Full Title: The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study)- a four arm randomised controlled trial
    Medical condition: We are investigating the phenomenon of ischaemic-reperfusion injury. Reperfusion of the ischaemic myocardium is known to cause further myocardial damage. We wish to investigate the phenomenon of Re...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000205-22 Sponsor Protocol Number: CYAD-N2T-005 Start Date*: 2018-06-04
    Sponsor Name:Celyad Onclogy SA
    Full Title: An open-label, Phase I/II study to assess the safety and clinical activity of NKR-2 treatment administration after a non-myeloablative preconditioning chemotherapy in relapse/refractory acute myelo...
    Medical condition: NKR-2 has the potential to treat many distinct tumor-types. This trial will focus on Relapsed and/or refractory (r/r) acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003858-14 Sponsor Protocol Number: HBO-SHA Start Date*: 2014-12-01
    Sponsor Name:Multidisciplinary Pain Center 7612, Rigshospitalet
    Full Title: Does Hyperbaric Oxygen Therapy Attenuate Secondary Hyperalgesia Areas Induced by a Thermal Injury in Human Volunteers? A Randomized Controlled Cross-over Study with a Blinded Observer.
    Medical condition: Experimental Inflammation
    Disease: Version SOC Term Classification Code Term Level
    17.1 10042613 - Surgical and medical procedures 10057480 Hyperbaric oxygen therapy PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001304-11 Sponsor Protocol Number: ACDHUVV-13 Start Date*: 2014-01-02
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    Full Title: Evaluation of myocardial and clinical beneficial effect of sevoflurane in intraoperative and postoperative myocardial revascularization surgery, compared with propofol
    Medical condition: Assessment of the beneficial effects of sevoflurane during the intraoperative and immediate postoperative myocardial revascularization surgery. Assessment will be through biochemical markers of myo...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005893-29 Sponsor Protocol Number: atp01 Start Date*: 2008-08-14
    Sponsor Name:RUNMC
    Full Title: Does ATP cause Annexin A5 targeting in the human forearm?
    Medical condition: atherosclerosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003601 Atherosclerosis LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-001965-26 Sponsor Protocol Number: AUTO4-TL1 Start Date*: 2018-02-01
    Sponsor Name:Autolus Ltd
    Full Title: A SINGLE ARM, OPEN-LABEL, MULTI-CENTRE, PHASE I/II STUDY EVALUATING THE SAFETY AND CLINICAL ACTIVITY OF AUTO4, A CAR T CELL TREATMENT TARGETING TRBC1, IN PATIENTS WITH RELAPSED OR REFRACTORY TRBC1 ...
    Medical condition: Relapsed or refractory T cell Non-Hodgkin Lymphoma (T-NHL)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10025321 Lymphomas non-Hodgkin's T-cell HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005327-33 Sponsor Protocol Number: CFTSp060 Start Date*: 2013-06-28
    Sponsor Name:The Christie NHS Foundation Trust
    Full Title: A Phase II Trial to Assess the Activity of NY-ESO-1 Targeted T Cells in Advanced Oesophagogastric Cancer
    Medical condition: Advanced Oesophago-gastric Cancer
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10056267 Gastroesophageal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000760-15 Sponsor Protocol Number: C-144-01 Start Date*: 2017-11-15
    Sponsor Name:Iovance Biotherapeutics, Inc.
    Full Title: A Phase 2, Multicenter Study to Assess the Efficacy and Safety of Autologous Tumor Infiltrating Lymphocytes (LN 144) for Treatment of Patients with Metastatic Melanoma
    Medical condition: Metastatic melanoma
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10027480 Metastatic malignant melanoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) HU (Completed) DE (Completed) ES (Ongoing) FR (Completed) IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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