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Clinical trials for Sevoflurane

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44356   clinical trials with a EudraCT protocol, of which   7382   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    97 result(s) found for: Sevoflurane. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2013-004582-14 Sponsor Protocol Number: XENOMICRO Start Date*: 2014-01-28
    Sponsor Name:Department of Anesthesiology and Perioperative Medicine
    Full Title: Haemodynamic effects of xenon or sevoflurane anesthesia on microcirculation
    Medical condition: Patients with ASA III classification (left ventricular failure) undergoing implantation of a defibrillator.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001552-29 Sponsor Protocol Number: 1271/2014 Start Date*: 2014-06-20
    Sponsor Name:Medizinische Universität Wien, Abteilung für Anästhesie und allgemeine Intensivmedizin
    Full Title: Determination of the minimal alveolar concentration of Sevoflurane in patient with end stage liver disease
    Medical condition: Orthotopic liver transplantation (OLT) is the only therapy for patients with liver failure. These patients have reduced anesthetic requirements compared with healthy patients. Sevoflurane has prove...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000071-90 Sponsor Protocol Number: AGO/2017/002 Start Date*: 2017-03-15
    Sponsor Name:Ghent University Hospital
    Full Title: Effect of sevoflurane and propofol on hepato-splanchnic pressure and flow during hepatobiliary surgery.
    Medical condition: patients scheduled for hepato-biliary surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003141-25 Sponsor Protocol Number: 1643/2015 Start Date*: 2015-10-06
    Sponsor Name:Medical University Vienna, Department of Anesthesia, Intensive Care Medicine and Pain Management
    Full Title: Determination of the minimal alveolar concentrations of sevoflurane in patients with end stage kidney disease
    Medical condition: Renal transplantation is the curative treatment in patients with end stage kidney disease. These patients have altered intraoperative anesthetic requirements compared with patients with maintained ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004604-29 Sponsor Protocol Number: 210710120713 Start Date*: 2015-04-27
    Sponsor Name:Jens Rolighed Larsen
    Full Title: Sevoflurane versus standard general anesthesia in elective open abdominal aortic aneurism surgery
    Medical condition: Abdominal aortic aneurism
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10002885 Aortic aneurysm repair PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-001379-34 Sponsor Protocol Number: SEVO-COVID19 Start Date*: 2020-04-14
    Sponsor Name:Instituto de Investigación Sanitaria INCLIVA
    Full Title: Sedation with sevoflurane versus propofol in patients with Acute Respiratory Distress Syndrome caused by COVID-19 infection
    Medical condition: Acute Respiratory Distress Syndrome caused by COVID19 infection
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001052 Acute respiratory distress syndrome PT
    20.0 100000004862 10051905 Coronavirus infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-004132-20 Sponsor Protocol Number: ALS-8-08-A-401 Start Date*: 2008-11-07
    Sponsor Name:Air Liquide Santé International
    Full Title: This protocol describes a total of three studies that are intrinsically linked. It does therefore have three titels. 1. The effect of xenon and sevoflurane on depth of hypnosis monitors when titrat...
    Medical condition: 1. The effect of xenon and sevoflurane on depth of hypnosis monitors when titrated to standard anesthesia parameter. 2. The efficacy of dexamethasone for prevention of PONV after xenon or sevoflura...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001908-38 Sponsor Protocol Number: 08042012 Start Date*: 2012-07-12
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: The effect of intravenous ketamine on the MAC of sevoflurane – a randomized, placebo controlled, double blinded clinical trial
    Medical condition: We want to test if intravenous s-ketamine of two different doses has an effect on MAC of sevoflurane
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-003737-19 Sponsor Protocol Number: CHUB-ITF-sevo-propofol Start Date*: 2023-01-10
    Sponsor Name:CHU Brugmann
    Full Title: Influence of sevoflurane and propofol on maximum muscular strength, speed of contraction and relaxation, in humans: A pilot study.
    Medical condition: Impact of anesthetic drugs on neuromuscular transmission
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002555-34 Sponsor Protocol Number: ECSEVO-LT-011 Start Date*: 2011-11-25
    Sponsor Name:FRANCISCO JAVIER BELDA
    Full Title: Study on the safety of administration of sevoflurane for long-term sedation in critical patients on assisted ventilation. A multicentric, randomised, controlled, prospective clinical trial.
    Medical condition: The general objective of this study is to perform an assessment of the safety of administration of sevoflurane for prolonged sedation of patients admitted to the Critical Care Unit.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10042613 Surgical and medical procedures SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-000556-11 Sponsor Protocol Number: RAPID_01 Start Date*: 2022-04-26
    Sponsor Name:Medical University of Vienna, Department of Anesthesia, Intensive Care Medicine and Pain Medicine
    Full Title: The effect of desflurane versus Sevoflurane on postoperative recovery in patients undergoing minor- to moderate-risk noncardiac surgery - a prospective double-blinded randomized clinical trial
    Medical condition: The evaluation of recovery times between desflurane and sevoflurane general anesthesia in patients ≥ 65 years of age undergoing minor- to moderate-risk noncardiac surgery
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001439-37 Sponsor Protocol Number: MACSevoPregabalin Start Date*: 2019-09-16
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Critical Care and Pain Management
    Full Title: The effect of pregabalin on the minimal alveolar concentration of sevoflurane
    Medical condition: This study aims to investigate the effect of clinically used doses of Pregabalin on the minimum alveolar concentration of sevoflurane to provide more information to clinicians using this adjunctive...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-000678-20 Sponsor Protocol Number: SEVODESHV Start Date*: 2014-09-02
    Sponsor Name:UZ Brussel
    Full Title: Does isocapnic hyperventilation hasten early recovery with sevoflurane and desflurane in O2/air?
    Medical condition: The absence of hypocapnia on the moment of emergence from general inhalatory anesthesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001304-11 Sponsor Protocol Number: ACDHUVV-13 Start Date*: 2014-01-02
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
    Full Title: Evaluation of myocardial and clinical beneficial effect of sevoflurane in intraoperative and postoperative myocardial revascularization surgery, compared with propofol
    Medical condition: Assessment of the beneficial effects of sevoflurane during the intraoperative and immediate postoperative myocardial revascularization surgery. Assessment will be through biochemical markers of myo...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001813-18 Sponsor Protocol Number: AOI_2019_JABAUDON Start Date*: 2020-07-29
    Sponsor Name:CHU de CLERMONT-FERRAND
    Full Title: Randomized Clinical Trial of Inhaled Sedation with Sevoflurane in Critically Ill Patients at Risk of Developing the Acute Respiratory Distress Syndrome
    Medical condition: Patients in ICU with risks of Acute Respiratory Distress Syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-000992-26 Sponsor Protocol Number: VAPOR002 Start Date*: 2016-06-29
    Sponsor Name:University Medical Center Groningen
    Full Title: Volatile Anesthetic Protection Of Renal transplants 2
    Medical condition: kidney transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) DK (Completed) ES (Completed) NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003151-36 Sponsor Protocol Number: AGO/2007/006 Start Date*: 2007-08-01
    Sponsor Name:University Hospital Ghent
    Full Title: Sevoflurane-Remifentanil interaction: Multiple response surfaces, validation of calibration stimuli, validation of the intraoperative isobole concept and investigating remifentanil induced opioid t...
    Medical condition: American Society of Anesthesia class I and II patients scheduled for surgery under general anesthesia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019420-31 Sponsor Protocol Number: no sponser Start Date*: 2011-04-22
    Sponsor Name:
    Full Title: ‘The influence of MAC values and behaviour of a child on emergence delirium after sevoflurane anaesthesia’
    Medical condition: ‘Emergence delirium’ (ED) is described as a mental disorder during recovery from general anaesthesia. After the introduction of new inhalation anaesthetics such as sevoflurane, this phenomenon agai...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002581-39 Sponsor Protocol Number: MISP-40750 Start Date*: 2014-05-05
    Sponsor Name:AZ Sint Jan Brugge-Oostende AV
    Full Title: Impact of deep neuromuscular block versus inhalation and TIVA on laparoscopic surgical workspace
    Medical condition: Not applicable
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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