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Clinical trials for Subfertility

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    18 result(s) found for: Subfertility. Displaying page 1 of 1.
    EudraCT Number: 2010-023867-17 Sponsor Protocol Number: S52775 Start Date*: 2011-03-25
    Sponsor Name:University Hospital Leuven
    Full Title: Impact of luteal phase support with vaginal progesterone on the clinical pregnancy rate in IUI cycles stimulated with gonadotrophins: a prospective randomized multicentre study.
    Medical condition: Subfertility
    Disease: Version SOC Term Classification Code Term Level
    12.1 10042391 Subfertility LLT
    12.1 10042392 Subfertility (female) LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004429-34 Sponsor Protocol Number: 2017.lipiodol.flush Start Date*: 2018-02-15
    Sponsor Name:UZ Brussel
    Full Title: Histological and Transcriptional Changes caused by Endometrial Flushing with Lipiodol: A Cross Over Study.
    Medical condition: Female subfertility
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042392 Subfertility (female) LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000993-32 Sponsor Protocol Number: S55300 Start Date*: 2013-05-07
    Sponsor Name:University Hospital Leuven
    Full Title: Does prolonged GnRH downregulation prior to ART improve the clinical pregnancy rate in postoperative endometriosis patients? A RCT
    Medical condition: endometriosis, subfertility
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004872 10042392 Subfertility (female) LLT
    15.1 100000004872 10014789 Endometriosis, site unspecified LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002000-13 Sponsor Protocol Number: rFSHdosingfinding.2018 Start Date*: 2019-01-09
    Sponsor Name:University hospital Brussel
    Full Title: Effect of recombinant FSH dosing following corifollitropin alfa in patients undergoing IVF/ICSI in a GnRH antagonist protocol: a randomized controlled dose-finding study.
    Medical condition: Subfertility in need of IVF and IVF-ICSI treatment
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042392 Subfertility (female) LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-002689-68 Sponsor Protocol Number: NL.23273.08 Start Date*: 2009-03-10
    Sponsor Name:Isala Klinieken, location Sophia
    Full Title: Cryo-thawed embryo transfer: natural versus artificial cycle. A non inferiority trial.
    Medical condition: Subfertility in need of IVF and IVF-ICSI treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012847-40 Sponsor Protocol Number: Pergoveris_Cetrorelix_1 Start Date*: 2009-11-11
    Sponsor Name:NHS Lothian [...]
    1. NHS Lothian
    2. The University of Edinburgh
    Full Title: A Randomised Study Comparing Two Different Regimens of Ovarian Stimulation Using Pergoveris and Cetrorelix for Controlled Ovarian Superovulation in Assisted Conception Treatment.
    Medical condition: Subfertility
    Disease: Version SOC Term Classification Code Term Level
    12. 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2018-000689-13 Sponsor Protocol Number: HRT1vs2week.2018 Start Date*: 2018-07-11
    Sponsor Name:University hospital Brussel
    Full Title: Clinical pregnancy rate for frozen embryo transfer with HRT: a pilot study comparing 1 versus 2 weeks of treatment
    Medical condition: Subfertility in need of IVF and IVF-ICSI treatment
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001034-18 Sponsor Protocol Number: NL43131-018-13 Start Date*: 2013-09-05
    Sponsor Name:AMC Amsterdam
    Full Title: Super ovulation in intrauterine insemination: FSH or Clomifene citrate
    Medical condition: Women diagnosed with unexplained subfertility or mild male factor subfertility with an indication for intra uterine insemination
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10021926 Infertility PT
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-005005-12 Sponsor Protocol Number: D2.D12.Bemfola Start Date*: 2018-05-28
    Sponsor Name:UZ Brussel
    Full Title: Initiation of ovarian stimulation with recombinant-human FSH (Bemfola®) in the late follicular phase, a randomised controlled study.
    Medical condition: Subfertility Oocyte donation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004872 10042392 Subfertility (female) LLT
    20.0 10042613 - Surgical and medical procedures 10053370 Oocyte donation PT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000106-29 Sponsor Protocol Number: T5/2013 Start Date*: 2013-03-19
    Sponsor Name:Turku University Hospital
    Full Title: GnRH analog as a luteal phase support in frozen-thawed embryo transfer cycles. A Pilot study
    Medical condition: Infertility
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004872 10042391 Subfertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001124-20 Sponsor Protocol Number: PCOS-5 Start Date*: 2005-04-18
    Sponsor Name:Sigrun Kjøtrød
    Full Title: Metformin treatment before IVF/ICSI in normal weight women with polycystic ovarian syndrome. A European, prospective, randomised, double blind, multicenter study.
    Medical condition: Polycystic ovary syndrome (PCOS) is a disorder characterized by polycystic ovaries, oligo-amenorrhea and hyperandrogenism. It is the most common endocrine disorder in women of fertile age. PCOS wom...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed) SE (Completed) FI (Completed) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-001014-15 Sponsor Protocol Number: S61372 Start Date*: 2018-06-26
    Sponsor Name:university hospital leuven
    Full Title: Frozen-thawed embryo transfer in a natural versus artificial cycle: a randomized clinical trial
    Medical condition: Patients with subfertility having frozen embryos after in vitro fertilization (IVF) or intracytoplasmatic sperm injection (ICSI)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-005420-42 Sponsor Protocol Number: S55983 Start Date*: 2014-02-06
    Sponsor Name:University Hospital Leuven
    Full Title: Is postoperative IUI better than expectant management in infertile endometriosis patients with good prognosis based on EFI score?
    Medical condition: (Sub)Fertility in endometriosis after laparoscopic removal of the endometriosos lesions: an RCT comparing intra-uterine insemination with expectant management
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004872 10042391 Subfertility LLT
    16.1 100000004872 10014789 Endometriosis, site unspecified LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001708-39 Sponsor Protocol Number: S54224 Start Date*: 2012-06-07
    Sponsor Name:University Hospital Leuven
    Full Title: Prospective randomized trial concerning three different stimulation methods in IVF/ICSI treatment in poor responders
    Medical condition: Subfertility
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038604 - Reproductive system and breast disorders 10016465 Fertility female decreased LLT
    14.1 10038604 - Reproductive system and breast disorders 10016398 Female infertility LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001307-35 Sponsor Protocol Number: FE999906 CS004 Start Date*: 2005-12-22
    Sponsor Name:Ferring Arzneimittel GmbH
    Full Title: A prospective, open label, randomised, parallel group, comparative pilot study to study the efficacy and safety of highly purified Menotrophin versus recombinant FSH (Follitropin alfa) administered...
    Medical condition: sub fertility
    Disease: Version SOC Term Classification Code Term Level
    7.1 10042391 LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2022-002310-16 Sponsor Protocol Number: LHinPOR001 Start Date*: 2023-02-01
    Sponsor Name:UZ Brussel
    Full Title: Endometrial gene expression profiles during ovarian stimulation with recombinant human FSH with or without the addition of recombinant human LH in genuine poor responders.
    Medical condition: Infertility
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-001835-22 Sponsor Protocol Number: MONACO Start Date*: 2021-10-20
    Sponsor Name:Ghent University Hospital
    Full Title: A randomized comparison of one controlled ovarian stimulation with corifollitropin alfa (CFA) versus up to three modified natural cycles (MNC) in expected and established poor responders
    Medical condition: this study will compare the efficacy of two different strategies for the management of predicted low prognosis patients under stimulation for IVF/ICSI: up to three MNCs (Modified Natural Cycle) (c...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-004985-21 Sponsor Protocol Number: BGB-A317-A1217-302(AdvanTIG-302) Start Date*: 2021-09-01
    Sponsor Name:BeiGene, Ltd.
    Full Title: A Phase 3, Randomized, Double-Blind Study of Ociperlimab, an Anti TIGIT Antibody, in Combination With Tislelizumab Compared to Pembrolizumab in Patients With Previously Untreated, PD L1 Selected, a...
    Medical condition: Previously Untreated, PD-L1-Selected, and Locally Advanced, Unresectable, or Metastatic Non-Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) FR (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned) PL (Trial now transitioned)
    Trial results: (No results available)
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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