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Clinical trials for Symptomatology

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    199 result(s) found for: Symptomatology. Displaying page 1 of 10.
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    EudraCT Number: 2014-004296-22 Sponsor Protocol Number: 2014-RdC-PRO-Th Start Date*: 2015-11-10
    Sponsor Name:Centre Eugène Marquis
    Full Title: Anticholinergics impact in the treatment of acute irritative urinary toxicity during radiotherapy for prostate cancer
    Medical condition: Symptomatology related to acute urinary toxicity occuring during prostate irradiation in patients suffering from prostate cancer.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004857 10004995 Bladder and urethral symptoms HLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002880-19 Sponsor Protocol Number: lapaz2006 Start Date*: 2006-09-14
    Sponsor Name:Servicio de psiquiatria. Hospital Universitario La Paz
    Full Title: Comparación de dos estrategias de intervención para el tratamiento de los trastornos depresivos en pacientes oncológicos
    Medical condition: Major depressive Disorder, one episode or several episodes. ICD: 296.2x, 296.3x
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000260-24 Sponsor Protocol Number: NAC600-ZI-L-01-06 Start Date*: 2007-05-21
    Sponsor Name:ZAMBON ITALIA
    Full Title: EVALUATION OF THE CLINICAL AND MICROBIOLOGICAL EFFICACY OF N-ACETILCISTEINA 600 MG, IN COMBINATION TO CEFPODOXIMA PROXETILE, IN THE THERAPY OF THE INFECTIONS OF THE HIGH RESPIRATORY WAYS IN ADULT P...
    Medical condition: Infection of the high respiratory ways in adult patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004054 Bacterial upper respiratory tract infections HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001482-17 Sponsor Protocol Number: F1D-MC-HGKQ(b) Start Date*: 2004-10-15
    Sponsor Name:Eli Lilly and Company
    Full Title: Olanzapine Versus Divalproex and Placebo in the Treatment of Mild to Moderate Mania Associated with Bipolar I disorder.
    Medical condition: Manic or Mixed Episodes Associated with Bipolar I Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001539-39 Sponsor Protocol Number: NV18-04-00260 Start Date*: 2019-06-17
    Sponsor Name:Národní ústav duševního zdraví
    Full Title: Clinical and neurobiological predictors of response to ketamine: towards personalized treatment of depression
    Medical condition: Moderate to severe depression without psychotic symptoms
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004984-31 Sponsor Protocol Number: DR180133 Start Date*: 2021-04-21
    Sponsor Name:CHRU TOURS
    Full Title: Nitrous Oxide in Resistant Depression in Elderly Subjects: A Randomized, Double-blind, Comparator Trial
    Medical condition: Resistant Depression in the Elderly Subject
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2007-005882-37 Sponsor Protocol Number: 524 Start Date*: 2008-01-17
    Sponsor Name:BAUSCH&LOMB
    Full Title: RANDOMIZED CONTROLLED CLINICAL STUDY ON THE EFFICACY AND TOLERABILITY OF 0.4% HYALURONIC ACID HYPOTONIC EYE DROPS (IALUREX) VS. HYDROXYPROPYL-GUAR EYE DROPS (SYSTANE) IN THE TREATMENT OF DRY EYE SY...
    Medical condition: Dry eye syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023350 Keratoconjunctivitis sicca LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005460-80 Sponsor Protocol Number: JMV001 Start Date*: 2006-12-05
    Sponsor Name:N/A
    Full Title: A single center, randomized, open-label, comparative study to assess efficacy and safety of piracetam 4.8g/d administered for 6 months as adjuvant to standard vestibular rehabilitation (VR) therapy...
    Medical condition: moderate to severe vertigo of peripheral origin
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001278-44 Sponsor Protocol Number: CLZ_TRS_TEA Start Date*: 2021-05-26
    Sponsor Name:Fundación Hospital Provincial de Castellón
    Full Title: Comparative analysis of the effectiveness of clozapine in resistant schizophrenia and schizoafective disorder.
    Medical condition: Treatment-resistant schizophrenia and schizoafective disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003529-41 Sponsor Protocol Number: ABR58805 Start Date*: 2017-02-22
    Sponsor Name:University Medical Center Utrecht
    Full Title: CANGLIA: Endocannabinoid control of microglia activation as a new therapeutic target in the treatment of schizophrenia
    Medical condition: Schizophrenia patients
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-001398-19 Sponsor Protocol Number: Exposition-DCS Start Date*: 2011-06-27
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: D-cycloserine augmented exposure therapy in patients with agoraphobia
    Medical condition: agarophobia with or without panic disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003842-27 Sponsor Protocol Number: Studio-flourochinoloni-in-BPCO. Start Date*: 2008-10-14
    Sponsor Name:CENTRO STUDI FADOI
    Full Title: Randomized, single-blind, parallel groups, controlled study to compare levofloxacin and prulifloxacin in patients with exacerbations of COPD previously treated with different antibiotics and admitt...
    Medical condition: - Patients with acute exacerbation of COPD of possible infectious origin, previously treated with antibiotic therapy (no quinolones), without clinical improvement, and hospitalized in Internal Medi...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005975-13 Sponsor Protocol Number: V00114 CP 201 Start Date*: 2006-04-25
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: Randomised, double-blind, placebo-controlled dose-effect study of V0114 (2.5, 5, 7.5 and 10 mg) versus mequitazine 10 mg and placebo in the treatment of seasonal allergic rhinitis.
    Medical condition: Prospective, multicentric, international, randomised, double-blind trial in six parallel groups: 4 doses of the test product, active control and placebo. This study is intended to evaluate the ef...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) FR (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002979-17 Sponsor Protocol Number: MANCOR Start Date*: 2014-01-27
    Sponsor Name:IVI Sevilla
    Full Title: Comparative study between the usage of corifollitropin alfa and daily recombinant FSH in the ovarian stimulation of low responders
    Medical condition: Low response to ovarian stimulation
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004527-32 Sponsor Protocol Number: SITADS Start Date*: 2016-11-22
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Kings College Hospital NHS Foundation Trust
    Full Title: Pilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes
    Medical condition: Depression in type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012378 Depression PT
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000762-35 Sponsor Protocol Number: ID_2882 Start Date*: 2011-11-18
    Sponsor Name:A.O. UNIVERSITARIA INTEGRATA DI VERONA
    Full Title: EFFECTS OF THE VITAMIN D ADMINISTRATION ON RESPIRATORY FUNCTIONS IN PAEDIATRIC PATIENTS SUFFERING FROM EFFORT ASTHMA
    Medical condition: paediatric patients suffering from effort asthma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003558 Asthma extrinsic LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001347-31 Sponsor Protocol Number: M13-954 Start Date*: 2013-11-12
    Sponsor Name:Abbott Laboratories GmbH
    Full Title: A Double-blind, Randomized, Multi-center, Placebo-controlled, Parallel-group Study to Assess the Effect of Creon® on Pancreatic Exocrine Insufficiency in Subjects with Diabetes Mellitus type 2
    Medical condition: Pancreatic exocrine insufficiency in diabetes type II
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004624-30 Sponsor Protocol Number: TOC17_01 Start Date*: 2018-05-16
    Sponsor Name:Linköping University
    Full Title: Modulating proinflammatory processes using tocilizumab in major depressive disorder
    Medical condition: Major depressive disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003971-20 Sponsor Protocol Number: ROS031019 Start Date*: 2020-03-03
    Sponsor Name:Rigshospitalet Glostrup
    Full Title: An open label study to evaluate the efficacy and tolerability of erenumab in the management of persistent redness and flushing in rosacea
    Medical condition: Rosacea
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10039218 Rosacea PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001085-15 Sponsor Protocol Number: LLB-2018-01 Start Date*: 2019-11-06
    Sponsor Name:LABO’LIFE Belgium sprl
    Full Title: Randomized, placebo-controlled, double-blind study to evaluate the efficacy of 2LHERP® in patients with recurrent orofacial herpes infections.
    Medical condition: Patients presenting recurrent orofacial herpes infections (6 or more episodes within the 12-months’ period prior to their study entry).
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10019972 Herpes viral infections HLT
    20.1 10021881 - Infections and infestations 10067152 Oral herpes PT
    21.1 10021881 - Infections and infestations 10019948 Herpes simplex PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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