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Clinical trials for Systolic dysfunction

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    211 result(s) found for: Systolic dysfunction. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2009-011006-42 Sponsor Protocol Number: vs.3.23-02-2009 Start Date*: 2009-07-13
    Sponsor Name:Rigshospitalet, Hjertemedicinsk afd. B
    Full Title: Sildenafil and diastolic dysfunction after AMI
    Medical condition: Diastolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052337 Diastolic dysfunction LLT
    9.1 10052337 Diastolic dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001150-88 Sponsor Protocol Number: MEN/03/ZOF-CHF/001 Start Date*: 2005-05-06
    Sponsor Name:Menarini International Operation Luxembourg -SA
    Full Title: Comparison between zofenopril and ramipril in combination with ASA on the extent of cardiovascular risk in patients with systolic left ventricular dysfunction after acute myocardial infarction (SMI...
    Medical condition: Systolic left ventricular dysfunction after AMI
    Disease: Version SOC Term Classification Code Term Level
    7.0 10049694 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-002020-25 Sponsor Protocol Number: 052017 Start Date*: 2018-08-31
    Sponsor Name:Odense University Hospital
    Full Title: ANGIOTENSIN–NEPRILYSIN INHIBITION IN DIASTOLIC DYSFUNCTION AFTER AMI
    Medical condition: Diastolic dysfunction after acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004849 10076396 Heart failure with preserved ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-011559-38 Sponsor Protocol Number: CL2-44121-004 Start Date*: 2010-03-16
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Evaluation of the effects of 4 oral dosages of S 44121 versus placebo on cardiac function and NT-proBNP in patients with chronic heart failure and left ventricular dysfunction not treated with a be...
    Medical condition: Chronic heart failure and left ventricular dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007558 Cardiac failure chronic PT
    14.1 10007541 - Cardiac disorders 10049694 Left ventricular dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) DE (Completed) ES (Completed) IT (Completed) GB (Completed) LV (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2017-000896-99 Sponsor Protocol Number: AC16148 Start Date*: 2017-06-20
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: A multicentre prospective randomised open-label blinded end-point controlled trial of high-sensitivity cardiac troponin I-guided combination angiotensin receptor blockade and beta blocker therapy t...
    Medical condition: Myocardial toxicity and the development of left ventricular systolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10007612 Cardiac troponin I increased LLT
    20.0 100000004849 10069501 Left ventricular systolic dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2018-003905-25 Sponsor Protocol Number: HAC2018-001 Start Date*: 2019-06-27
    Sponsor Name:H.A.C. Pharma
    Full Title: Evaluation of efficacy and tolerance of fludrocortisone (Flucortac) in the treatment of neurogenic orthostatic hypotension
    Medical condition: Neurogenic Orthostatic Hypotension (NOH)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10031127 Orthostatic hypotension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-014940-12 Sponsor Protocol Number: CL2-44121-006 Start Date*: 2010-03-11
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Evaluation of the anti-arrhythmic effects of 3 oral dosages of S 44121 versus placebo in patients with chronic heart failure and left ventricular systolic dysfunction at risk for ventricular arrhyt...
    Medical condition: Chronic Heart Failure and left ventricular systolic dysfunction at risk for ventricular arrhythmia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10007558 Cardiac failure chronic LLT
    12.1 10049694 Left ventricular dysfunction LLT
    12.1 10047281 Ventricular arrhythmia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Completed) SK (Completed) ES (Completed) PT (Completed) GB (Completed) CZ (Completed) DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011558-16 Sponsor Protocol Number: CL2-44121-003 Start Date*: 2010-03-16
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Evaluation of the effects of 4 oral dosages of S 44121 versus placebo on cardiac function and NT-proBNP in patients with chronic heart failure and left ventricular dysfunction. A 12-week, randomize...
    Medical condition: Chronic heart failure and left ventricular dysfunction
    Disease: Version SOC Term Classification Code Term Level
    12.0 10007558 Cardiac failure chronic LLT
    12.0 10049694 Left ventricular dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed) DE (Completed) ES (Completed) IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005278-59 Sponsor Protocol Number: 20050222 Start Date*: 2006-12-22
    Sponsor Name:Amgen Inc.
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Darbepoetin Alfa Treatment on Mortality and Morbidity in Heart Failure (HF) Subjects with Symp...
    Medical condition: Heart Failure Subjects with Symptomatic Left Ventricular Systolic Dysfunction and Anemia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10007559 Cardiac failure congestive PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed) LT (Completed) SK (Completed) BE (Completed) EE (Completed) FI (Completed) HU (Completed) DK (Completed) DE (Completed) CZ (Completed) ES (Completed) SE (Completed) AT (Completed) PT (Completed) NL (Completed) LV (Completed) IT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2006-003075-12 Sponsor Protocol Number: 290478 Start Date*: Information not available in EudraCT
    Sponsor Name:Department Of Paediatric Cardiology
    Full Title: Effect of carvedilol on left ventricular systolic and diastolic function and the neurohormonal axis in patients with Duchenne muscular dystrophy and left ventricular dysfunction.
    Medical condition: Duchenne muscular dystrophy is an X-linked inherited disorder which primarily affects skeletal muscle through a mutation in dystrophin which maps to the long arm of the X chromosome (Xp21). Patient...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002520-33 Sponsor Protocol Number: SNT-II-1 Start Date*: 2005-09-06
    Sponsor Name:Santhera Pharmaceuticals LLC
    Full Title: A Phase IIa double blind, randomised, placebo controlled, single centre study at the university of Leuven to assess the efficacy and tolerability of idebenone in 10 - 16 year old males with cardiac...
    Medical condition: Duchenne Muscular Dystrophy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004683-38 Sponsor Protocol Number: G113 Start Date*: 2015-01-26
    Sponsor Name:Fondazione per il Tuo cuore onlus-ANMCO
    Full Title: Effects of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin on left ventricular myocardial DYsfunction in patients with type 2 DiAbetes mellitus and concentric left ventricular geometry.
    Medical condition: Type 2 Diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    17.1 10014698 - Endocrine disorders 10018424 Glucose metabolism disorders (incl diabetes mellitus) HLGT
    17.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    17.1 10027433 - Metabolism and nutrition disorders 10027433 Metabolism and nutrition disorders SOC
    17.1 10014698 - Endocrine disorders 10012602 Diabetes mellitus (incl subtypes) HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001005-27 Sponsor Protocol Number: 1818 Start Date*: 2011-05-02
    Sponsor Name:Department of Anaesthesiology, University Hospital of Skejby
    Full Title: The effect of dobtutamin on postoperative systolic deformation and diastolic function in patients with concentric hypertrophy of the left ventricle
    Medical condition: Aortic stenosis Diastolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10002907 Aortic stenosis & incompetence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003273-42 Sponsor Protocol Number: 14AOI11 Start Date*: 2014-12-23
    Sponsor Name:CHU de Nice
    Full Title: Comparing a diuretic vascular filling in the initial management of acute pulmonary embolism with right ventricular dysfunction normotensive
    Medical condition: acute pulmonary embolism with right ventricular dysfunction normotensive
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004855 10050071 Embolism lung LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002269-21 Sponsor Protocol Number: 01.00240 Start Date*: 2013-12-06
    Sponsor Name:Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine, University of Porto
    Full Title: Metformin in diastolic dysfunction of metabolic syndrome
    Medical condition: Diastolic dysfunction in non-diabetic patients with metabolic syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-002627-15 Sponsor Protocol Number: BAY94-8862/14564 Start Date*: 2013-05-27
    Sponsor Name:Bayer HealthCare AG
    Full Title: A randomized, double-blind, double-dummy, multi-center study to assess safety and efficacy of BAY 94-8862 in subjects with emergency presentation at the hospital because of worsening chronic heart ...
    Medical condition: Subjects with worsening chronic heart failure (WCHF) and left ventricular systolic dysfunction and either type 2 diabetes mellitus (DM type 2) with or without chronic kidney disease (CKD) or modera...
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004857 10064848 Chronic kidney disease LLT
    16.1 100000004861 10045242 Type II diabetes mellitus LLT
    16.1 100000004849 10066498 Cardiac failure chronic aggravated LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) AT (Completed) SE (Completed) LT (Completed) DE (Completed) HU (Completed) CZ (Completed) NO (Completed) NL (Completed) PT (Completed) DK (Completed) IT (Completed) ES (Completed) BG (Completed) GR (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2015-001196-46 Sponsor Protocol Number: OPHT-240215 Start Date*: 2015-05-15
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of simvastatin withdrawal on ocular endothelial function
    Medical condition: endothelial dysfunction in cardiovascular diseases
    Disease: Version SOC Term Classification Code Term Level
    19.1 10047065 - Vascular disorders 10048554 Endothelial dysfunction PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002057-34 Sponsor Protocol Number: PRePED-01 Start Date*: 2020-02-07
    Sponsor Name:Fundación de Investigación Biomédica Hospital Puerta de Hierro
    Full Title: A RANDOMISED, DOUBLE-BLIND CONTROLLED TRIAL TO EVALUATE THE EFFICACY OF INTRACAVERNOSAL INFUSION OF PLATELET RICH PLASMA (PRP) AGAINST PLATELET POOR PLASMA (PPP) IN THE TREATMENT OF VASCULOGENIC ER...
    Medical condition: Vascular Erectile Dysfunction
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10061461 Erectile dysfunction PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001704-37 Sponsor Protocol Number: CSPP100A2340 Start Date*: 2006-11-03
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 36 week, multicenter, randomized, double-blind, placebo- controlled, parallel-group, pilot study to evaluate the efficacy and safety of aliskiren on the prevention of left ventricular remodeling ...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) DE (Completed) SE (Completed) BE (Completed) CZ (Completed) HU (Completed) GB (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-000191-15 Sponsor Protocol Number: CORO-RYC-001 Start Date*: 2018-06-13
    Sponsor Name:IRICYS- Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal
    Full Title: Effectiveness and Safety on Cardiac Frecuency Control With Ivabradine on the Cardiogenic Shock. (ES-FISH)
    Medical condition: Cardiogenic Shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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